The network for 'maturation of lsu rrna' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

maturation of lsu rrna

Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
NOP7 Nop7p 0.996
MAK21 Mak21p 0.993
NOP4 Nop4p 0.990
NOC2 Noc2p 0.988
SSF1 Ssf1p 0.988
RLP7 Rlp7p 0.986
RPF2 Rpf2p 0.981
DBP10 Dbp10p 0.980
NOP2 Nop2p 0.980
BRX1 Brx1p 0.980
NOG1 Nog1p 0.978
CIC1 Cic1p 0.967
NIP7 Nip7p 0.967
TIF6 Tif6p 0.958
NSA1 Nsa1p 0.958
PUF6 Puf6p 0.956
HAS1 Has1p 0.943
ERB1 Erb1p 0.935
DRS1 Drs1p 0.933
NOC3 Noc3p 0.911
YTM1 Ytm1p 0.910
MAK11 Mak11p 0.880
RPF1 Rpf1p 0.875
NUG1 Nug1p 0.768
NOP12 Nop12p 0.763
LOC1 Loc1p 0.739
NOP15 Nop15p 0.730
EBP2 Ebp2p 0.715
RRS1 Rrs1p 0.693
RPL8B Rpl8bp 0.637
DBP7 Dbp7p 0.559
NOP8 Nop8p 0.540
RPL5 Rpl5p 0.526
MAK5 Mak5p 0.513
NOP13 Nop13p 0.512
RRP15 Rrp15p 0.506
RRP5 Rrp5p 0.490
RIX7 Rix7p 0.436
MRT4 Mrt4p 0.433
ARX1 Arx1p 0.410
RIX1 Rix1p 0.343
MTR4 Mtr4p 0.329
RRP14 Rrp14p 0.317
SPB4 Spb4p 0.304
RRP17 Rrp17p 0.292
NOG2 Nog2p 0.267
PWP1 Pwp1p 0.258
URB2 Urb2p 0.248
NOP16 Nop16p 0.237
NOP6 Nop6p 0.219
RRP36 Rrp36p 0.211
HCA4 Hca4p 0.208
RRP1 Rrp1p 0.165
DBP2 Dbp2p 0.164
NOP1 Nop1p 0.163
RAI1 Rai1p 0.163
RPL3 Rpl3p 0.151
NSA2 Nsa2p 0.147
RLP24 Rlp24p 0.146
DBP3 Dbp3p 0.142
CBF5 Cbf5p 0.136
FYV7 Fyv7p 0.129
UBP10 Ubp10p 0.116
RRP12 Rrp12p 0.105
RPL7B Rpl7bp 0.103
FPR4 Fpr4p 0.103
MDN1 Mdn1p 0.101
RPL1B Rpl1bp 0.100
KRI1 Kri1p 0.100
PXR1 Pxr1p 0.095
RPL4B Rpl4bp 0.090
UAF30 Uaf30p 0.090
NOP58 Nop58p 0.090
GLN4 Gln4p 0.080
FUN12 Fun12p 0.077
YLR063W hypothetical protein 0.071
RPL2B Rpl2bp 0.071
DBP9 Dbp9p 0.071
RPL19A Rpl19ap 0.067
RPA135 Rpa135p 0.065
SPB1 Spb1p 0.063
RAT1 Rat1p 0.063
FPR3 Fpr3p 0.059
RPL27A Rpl27ap 0.058
RPL30 Rpl30p 0.057
LAS1 Las1p 0.055
RRP40 Rrp40p 0.055
BUD23 Bud23p 0.054
ARB1 Arb1p 0.054
GAR1 Gar1p 0.053
FRK1 Frk1p 0.052
RSA3 Rsa3p 0.051
TMA46 Tma46p 0.051
TRZ1 Trz1p 0.049
YLR264C-A hypothetical protein 0.047
SRD1 Srd1p 0.046
TRL1 Trl1p 0.046
YGR283C hypothetical protein 0.045
ARG8 Arg8p 0.044
NOB1 Nob1p 0.042
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
LYAR Ly1 antibody reactive homolog (mouse) 0.991
MYBBP1A MYB binding protein (P160) 1a 0.861
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.855
NOP56 NOP56 ribonucleoprotein homolog (yeast) 0.750
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.649
NOP2 NOP2 nucleolar protein homolog (yeast) 0.611
C10orf2 chromosome 10 open reading frame 2 0.534
PUS1 pseudouridylate synthase 1 0.513
PPAN peter pan homolog (Drosophila) 0.443
PAK1IP1 PAK1 interacting protein 1 0.425
PDCD11 programmed cell death 11 0.418
DKC1 dyskeratosis congenita 1, dyskerin 0.403
RBM28 RNA binding motif protein 28 0.387
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.375
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.375
WDR3 WD repeat domain 3 0.337
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) 0.334
BOP1 block of proliferation 1 0.326
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 0.269
IPO4 importin 4 0.267
PES1 pescadillo homolog 1, containing BRCT domain (zebrafish) 0.245
NOP58 NOP58 ribonucleoprotein homolog (yeast) 0.241
WDR75 WD repeat domain 75 0.218
TRMT1 TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae) 0.213
PUS7 pseudouridylate synthase 7 homolog (S. cerevisiae) 0.189
NOL8 nucleolar protein 8 0.189
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.147
NSUN2 NOP2/Sun domain family, member 2 0.141
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.126
WDR74 WD repeat domain 74 0.121
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 0.121
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 0.120
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.109
NOL11 nucleolar protein 11 0.098
HEATR1 HEAT repeat containing 1 0.098
DDX21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 0.096
WDR43 WD repeat domain 43 0.089
KIAA0020 KIAA0020 0.083
GTPBP4 GTP binding protein 4 0.078
RPL29 ribosomal protein L29 0.077
U2SURP U2 snRNP-associated SURP domain containing 0.075
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.073
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.071
BMS1 BMS1 homolog, ribosome assembly protein (yeast) 0.067
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.062
NOP14 NOP14 nucleolar protein homolog (yeast) 0.060
RIOK1 RIO kinase 1 (yeast) 0.056
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.056
DIEXF digestive organ expansion factor homolog (zebrafish) 0.055
DPH2 DPH2 homolog (S. cerevisiae) 0.055
NAT10 N-acetyltransferase 10 (GCN5-related) 0.054
FTSJ3 FtsJ homolog 3 (E. coli) 0.052
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.052
EIF3H eukaryotic translation initiation factor 3, subunit H 0.052
WDR12 WD repeat domain 12 0.049
MAK16 MAK16 homolog (S. cerevisiae) 0.048
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.048
PTRH2 peptidyl-tRNA hydrolase 2 0.046
GAR1 GAR1 ribonucleoprotein homolog (yeast) 0.045
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.045
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.044
ATAD3A ATPase family, AAA domain containing 3A 0.044
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.043
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.043
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 0.043
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.042
PWP1 PWP1 homolog (S. cerevisiae) 0.042
EIF3B eukaryotic translation initiation factor 3, subunit B 0.041
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.040
EIF5B eukaryotic translation initiation factor 5B 0.040
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 0.039
C12orf11 chromosome 12 open reading frame 11 0.039
WDR46 WD repeat domain 46 0.038
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.037
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.037
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 0.037
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 0.035
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.035
PELP1 proline, glutamate and leucine rich protein 1 0.035
ASCC3 activating signal cointegrator 1 complex subunit 3 0.033
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.033
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 0.032
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.032
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 0.031
LAS1L LAS1-like (S. cerevisiae) 0.031
CUL1 cullin 1 0.030
TDG thymine-DNA glycosylase 0.029
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.029
OTUD6B OTU domain containing 6B 0.028
ZC3H15 zinc finger CCCH-type containing 15 0.028
RPL36 ribosomal protein L36 0.028
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 0.028
NOM1 nucleolar protein with MIF4G domain 1 0.028
TTC27 tetratricopeptide repeat domain 27 0.028
BRIX1 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) 0.027
AMD1 adenosylmethionine decarboxylase 1 0.027
RPL4 ribosomal protein L4 0.027
METTL1 methyltransferase like 1 0.027
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.026
GRWD1 glutamate-rich WD repeat containing 1 0.026
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Mus musculus
Name Description Probability Func Analog Organism
Mybbp1a MYB binding protein (P160) 1a 0.608
Nop2 NOP2 nucleolar protein homolog (yeast) 0.606
Ppan peter pan homolog (Drosophila) 0.405
Wdr74 WD repeat domain 74 0.404
Nop56 NOP56 ribonucleoprotein homolog (yeast) 0.232
Ccdc86 coiled-coil domain containing 86 0.196
Pprc1 peroxisome proliferative activated receptor, gamma, coactivator-related 1 0.173
Eed embryonic ectoderm development 0.157
Wdr46 WD repeat domain 46 0.121
Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.111
Eif3d eukaryotic translation initiation factor 3, subunit D 0.109
Wdr43 WD repeat domain 43 0.098
Srsf7 serine/arginine-rich splicing factor 7 0.092
Pus1 pseudouridine synthase 1 0.087
Ddx21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 0.087
Utp20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.085
Rrp1b ribosomal RNA processing 1 homolog B (S. cerevisiae) 0.084
Cirh1a cirrhosis, autosomal recessive 1A (human) 0.081
Grwd1 glutamate-rich WD repeat containing 1 0.078
Nolc1 nucleolar and coiled-body phosphoprotein 1 0.075
Gnl3 guanine nucleotide binding protein-like 3 (nucleolar) 0.075
Srm spermidine synthase 0.065
Gpatch4 G patch domain containing 4 0.063
D19Bwg1357e DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed 0.060
Pwp2 PWP2 periodic tryptophan protein homolog (yeast) 0.054
Rars arginyl-tRNA synthetase 0.050
Eif3g eukaryotic translation initiation factor 3, subunit G 0.050
Mak16 MAK16 homolog (S. cerevisiae) 0.048
Gtf2f1 general transcription factor IIF, polypeptide 1 0.047
Smn1 survival motor neuron 1 0.043
Nop58 NOP58 ribonucleoprotein homolog (yeast) 0.040
Ftsj3 FtsJ homolog 3 (E. coli) 0.037
Zfp259 zinc finger protein 259 0.036
Abt1 activator of basal transcription 1 0.036
Aatf apoptosis antagonizing transcription factor 0.034
Elac2 elaC homolog 2 (E. coli) 0.034
Smyd5 SET and MYND domain containing 5 0.033
Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 0.033
Nop14 NOP14 nucleolar protein homolog (yeast) 0.031
Exosc10 exosome component 10 0.031
Rbm19 RNA binding motif protein 19 0.030
Nip7 nuclear import 7 homolog (S. cerevisiae) 0.029
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.028
Surf6 surfeit gene 6 0.027
Nufip1 nuclear fragile X mental retardation protein interacting protein 1 0.027
Mrto4 MRT4, mRNA turnover 4, homolog (S. cerevisiae) 0.027
Rrp15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.026
Abcf1 ATP-binding cassette, sub-family F (GCN20), member 1 0.026
Ipo4 importin 4 0.026
Fbl fibrillarin 0.026
Prmt5 protein arginine N-methyltransferase 5 0.026
Rrp9 RRP9, small subunit (SSU) processome component, homolog (yeast) 0.025
Dimt1 DIM1 dimethyladenosine transferase 1-like (S. cerevisiae) 0.025
Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.024
Gnl2 guanine nucleotide binding protein-like 2 (nucleolar) 0.023
Sdad1 SDA1 domain containing 1 0.023
Ddx10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.022
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.022
Ltv1 LTV1 homolog (S. cerevisiae) 0.022
Mrps18b mitochondrial ribosomal protein S18B 0.021
Heatr1 HEAT repeat containing 1 0.021
Ttc27 tetratricopeptide repeat domain 27 0.021
Ruvbl2 RuvB-like protein 2 0.021
Eif6 eukaryotic translation initiation factor 6 0.021
Rnaseh1 ribonuclease H1 0.020
Cct2 chaperonin containing Tcp1, subunit 2 (beta) 0.020
Polr1e polymerase (RNA) I polypeptide E 0.019
Trp53 transformation related protein 53 0.017
Dnajc2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.017
Imp4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 0.017
Mettl1 methyltransferase like 1 0.017
Usp39 ubiquitin specific peptidase 39 0.017
Cct8 chaperonin containing Tcp1, subunit 8 (theta) 0.017
Gar1 GAR1 ribonucleoprotein homolog (yeast) 0.016
Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.016
Myc myelocytomatosis oncogene 0.015
Igh immunoglobulin heavy chain complex 0.015
Rrp7a ribosomal RNA processing 7 homolog A (S. cerevisiae) 0.015
Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha 0.014
Farsa phenylalanyl-tRNA synthetase, alpha subunit 0.014
Hars histidyl-tRNA synthetase 0.014
Exosc1 exosome component 1 0.014
Surf2 surfeit gene 2 0.014
Ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.014
Ddx51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 0.014
Jmjd6 jumonji domain containing 6 0.013
Ddx49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 0.013
Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.013
Nop16 NOP16 nucleolar protein homolog (yeast) 0.013
Nmd3 NMD3 homolog (S. cerevisiae) 0.013
Ebna1bp2 EBNA1 binding protein 2 0.013
Adrm1 adhesion regulating molecule 1 0.013
Trmt1 TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae) 0.012
Qtrt1 queuine tRNA-ribosyltransferase 1 0.012
Wdr75 WD repeat domain 75 0.012
Ddx41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 0.012
Dph5 DPH5 homolog (S. cerevisiae) 0.012
Las1l LAS1-like (S. cerevisiae) 0.012
Utp14a UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.012
Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism