The network for 'endonucleolytic cleavage involved in rrna processing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endonucleolytic cleavage involved in rrna processing

Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
NOP1 Nop1p 0.967
FAF1 Faf1p 0.962
UTP18 Utp18p 0.941
SOF1 Sof1p 0.938
ENP1 Enp1p 0.916
BFR2 Bfr2p 0.896
ECM16 Ecm16p 0.891
MRD1 Mrd1p 0.865
MPP10 Mpp10p 0.862
KRR1 Krr1p 0.858
DIP2 Dip2p 0.813
KRE33 Kre33p 0.756
ENP2 Enp2p 0.754
UBP10 Ubp10p 0.740
IMP3 Imp3p 0.726
NOP8 Nop8p 0.700
UTP8 Utp8p 0.616
ESF2 Esf2p 0.600
UTP7 Utp7p 0.594
BUD21 Bud21p 0.579
UTP13 Utp13p 0.579
UTP11 Utp11p 0.569
BMS1 Bms1p 0.542
UTP4 Utp4p 0.540
NOP14 Nop14p 0.538
UTP25 Utp25p 0.526
SLX9 Slx9p 0.498
UTP23 Utp23p 0.486
RRP5 Rrp5p 0.442
UTP10 Utp10p 0.430
UTP21 Utp21p 0.411
UTP30 Utp30p 0.396
TRM112 Trm112p 0.391
NAN1 Nan1p 0.369
ESF1 Esf1p 0.368
PXR1 Pxr1p 0.347
RRP36 Rrp36p 0.346
SAS10 Sas10p 0.330
UTP9 Utp9p 0.325
IMP4 Imp4p 0.298
RRP14 Rrp14p 0.282
RPS17A Rps17ap 0.262
RRP12 Rrp12p 0.261
EMG1 Emg1p 0.256
LCP5 Lcp5p 0.250
NOP6 Nop6p 0.240
RPS18B Rps18bp 0.230
RIO2 Rio2p 0.230
NOP2 Nop2p 0.211
PWP2 Pwp2p 0.210
RIO1 Rio1p 0.201
RRP9 Rrp9p 0.197
TSR1 Tsr1p 0.188
GAR1 Gar1p 0.182
NOB1 Nob1p 0.157
RRP7 Rrp7p 0.152
NOP56 Nop56p 0.144
EBP2 Ebp2p 0.144
RIX7 Rix7p 0.143
PNO1 Pno1p 0.124
UTP14 Utp14p 0.120
DHR2 Dhr2p 0.119
RPS28B Rps28bp 0.116
EFG1 Efg1p 0.115
RPL22A Rpl22ap 0.115
FYV7 Fyv7p 0.114
RRP3 Rrp3p 0.112
URA2 Ura2p 0.106
NSA2 Nsa2p 0.104
LRP1 Lrp1p 0.102
UTP15 Utp15p 0.099
SRP21 Srp21p 0.093
FUN12 Fun12p 0.092
RPS30B Rps30bp 0.092
MTR3 Mtr3p 0.089
GLN1 Gln1p 0.087
SGD1 Sgd1p 0.086
CBF5 Cbf5p 0.085
GRC3 Grc3p 0.085
RPF1 Rpf1p 0.084
PRS2 Prs2p 0.083
RET1 Ret1p 0.081
NOC4 Noc4p 0.081
RPP2A Rpp2ap 0.079
RCL1 Rcl1p 0.078
FCF1 Fcf1p 0.078
NSP1 Nsp1p 0.077
DED1 Ded1p 0.074
RPL37A Rpl37ap 0.073
RPS4A Rps4ap 0.072
ROK1 Rok1p 0.072
RPS21A Rps21ap 0.072
RPA43 Rpa43p 0.072
RSA4 Rsa4p 0.071
FCF2 Fcf2p 0.070
RPS29A Rps29ap 0.070
NOP9 Nop9p 0.068
PRS3 Prs3p 0.068
UTP20 Utp20p 0.067
PRP28 Prp28p 0.067
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
CELE_C24H12.4 Protein C24H12.4 0.860
W07E6.2 Protein W07E6.2 0.760
tag-184 Protein TAG-184 0.727
rbd-1 Protein RBD-1 0.713
F27C1.6 Protein F27C1.6 0.705
K07H8.10 Protein K07H8.10 0.643
CELE_T26G10.1 Protein T26G10.1 0.553
Y53C12B.1 Protein Y53C12B.1 0.510
pro-1 Protein PRO-1 0.476
K07C5.4 Protein K07C5.4 0.455
K12H4.3 Protein K12H4.3 0.425
wdr-46 Protein WDR-46 0.407
dao-5 Protein DAO-5 0.393
ZK512.2 Protein ZK512.2 0.388
ZK546.14 Protein ZK546.14 0.372
CELE_T06E6.1 Protein T06E6.1 0.367
rha-2 Protein RHA-2 0.364
ZK792.5 Protein ZK792.5 0.335
F54C9.9 Protein F54C9.9 0.334
CELE_F23B12.7 Protein F23B12.7 0.312
tag-151 Protein TAG-151 0.289
let-716 Protein LET-716 0.283
mrps-18C Protein MRPS-18C 0.270
Y45F10D.7 Protein Y45F10D.7 0.267
F55F8.2 Protein F55F8.2 0.264
nol-1 Protein NOL-1 0.251
nath-10 Protein NATH-10 0.246
CELE_F53F4.11 Protein F53F4.11 0.238
K04C2.2 Protein K04C2.2 0.229
F09F7.3 Protein F09F7.3 0.226
R02F2.7 Protein R02F2.7 0.217
puf-12 Protein PUF-12 0.214
fib-1 Protein FIB-1 0.213
C53H9.2 Protein C53H9.2 0.197
F58B3.4 Protein F58B3.4 0.192
W04C9.4 Protein W04C9.4 0.167
ZK686.2 Protein ZK686.2 0.145
H06I04.3 Protein H06I04.3 0.134
Y48G1A.4 Protein Y48G1A.4 0.131
CELE_Y54H5A.1 Protein Y54H5A.1 0.130
F49D11.10 Protein F49D11.10 0.119
rrbs-1 Protein RRBS-1 0.116
F25B5.5 Protein F25B5.5 0.109
nol-5 Protein NOL-5 0.107
CELE_Y48B6A.1 Protein Y48B6A.1 0.105
R05D11.4 Protein R05D11.4 0.102
lpd-2 Protein LPD-2 0.101
C18A3.3 Protein C18A3.3 0.100
C47E12.7 Protein C47E12.7 0.093
tag-124 Protein TAG-124 0.088
Y66H1A.4 Protein Y66H1A.4 0.087
ZK430.7 Protein ZK430.7 0.087
T08B2.5 Protein T08B2.5 0.084
ZK1127.4 Protein ZK1127.4 0.082
C05C8.2 Protein C05C8.2 0.073
K01G5.5 Protein K01G5.5 0.068
Y46E12BL.2 Protein Y46E12BL.2 0.068
toe-1 Protein TOE-1 0.066
K05C4.5 Protein K05C4.5 0.066
F18C12.3 Protein F18C12.3 0.060
Y37E11B.5 Protein Y37E11B.5 0.054
F13H8.2 Protein F13H8.2 0.054
rpb-2 Protein RPB-2 0.052
CELE_ZK795.3 Protein ZK795.3 0.052
pro-2 Protein PRO-2 0.051
T20B12.3 Protein T20B12.3 0.050
C37H5.5 Protein C37H5.5 0.050
CELE_Y52B11A.10 Protein Y52B11A.10 0.048
tut-1 Protein TUT-1 0.048
ngp-1 Protein NGP-1 0.044
Y48E1A.1 Protein Y48E1A.1 0.039
ears-1 Protein EARS-1 0.039
eif-3.B Protein EIF-3.B 0.037
F11A10.7 Protein F11A10.7 0.036
Y73E7A.2 Protein Y73E7A.2 0.034
glh-1 Protein GLH-1 0.034
Y94H6A.5 Protein Y94H6A.5 0.034
CELE_T04A8.6 Protein T04A8.6 0.033
nst-1 Protein NST-1 0.033
Y23H5B.6 Protein Y23H5B.6 0.033
CELE_Y54E5B.2 Protein Y54E5B.2 0.032
F55F8.3 Protein F55F8.3 0.032
ama-1 Protein AMA-1 0.032
lpd-6 Protein LPD-6 0.030
T10B5.3 Protein T10B5.3 0.030
ruvb-2 Protein RUVB-2 0.029
T12E12.3 Protein T12E12.3 0.028
F55A3.2 Protein F55A3.2 0.028
dis-3 Protein DIS-3 0.028
prmt-7 Protein PRMT-7 0.027
fust-1 Protein FUST-1 0.027
abcf-3 Protein ABCF-3 0.024
egl-45 Protein EGL-45 0.023
acin-1 Protein ACIN-1 0.023
CELE_F07E5.5 Protein F07E5.5 0.022
fbf-2 Protein FBF-2 0.021
T23D8.3 Protein T23D8.3 0.019
C44E4.4 Protein C44E4.4 0.019
Y71G12B.8 Protein Y71G12B.8 0.019
B0024.11 Protein B0024.11 0.018
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Gnl3 guanine nucleotide binding protein-like 3 (nucleolar) 0.758
Mybbp1a MYB binding protein (P160) 1a 0.705
Wdr43 WD repeat domain 43 0.615
Grwd1 glutamate-rich WD repeat containing 1 0.510
Nop2 NOP2 nucleolar protein homolog (yeast) 0.414
Polr1b polymerase (RNA) I polypeptide B 0.264
Ddx21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 0.253
Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.233
Utp20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.233
Eed embryonic ectoderm development 0.225
Rrp9 RRP9, small subunit (SSU) processome component, homolog (yeast) 0.220
Tsr1 TSR1, 20S rRNA accumulation, homolog (yeast) 0.213
Ppan peter pan homolog (Drosophila) 0.200
Pprc1 peroxisome proliferative activated receptor, gamma, coactivator-related 1 0.190
Smyd5 SET and MYND domain containing 5 0.173
Mettl1 methyltransferase like 1 0.172
Srm spermidine synthase 0.163
Wdr46 WD repeat domain 46 0.162
Ftsj3 FtsJ homolog 3 (E. coli) 0.158
Tex10 testis expressed gene 10 0.136
Fam203a family with sequence similarity 203, member A 0.124
Pwp2 PWP2 periodic tryptophan protein homolog (yeast) 0.109
Rbm19 RNA binding motif protein 19 0.108
Bysl bystin-like 0.096
Tbrg4 transforming growth factor beta regulated gene 4 0.089
Cebpz CCAAT/enhancer binding protein zeta 0.084
Rrp15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.082
D19Bwg1357e DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed 0.072
Rrp1b ribosomal RNA processing 1 homolog B (S. cerevisiae) 0.069
Suz12 suppressor of zeste 12 homolog (Drosophila) 0.067
Nsun2 NOL1/NOP2/Sun domain family member 2 0.065
Ccdc86 coiled-coil domain containing 86 0.064
Cirh1a cirrhosis, autosomal recessive 1A (human) 0.063
Polr1a polymerase (RNA) I polypeptide A 0.055
Elac2 elaC homolog 2 (E. coli) 0.055
2610027L16Rik RIKEN cDNA 2610027L16 gene 0.052
Eif1a eukaryotic translation initiation factor 1A 0.049
Spata5 spermatogenesis associated 5 0.048
Xpo5 exportin 5 0.048
Nop14 NOP14 nucleolar protein homolog (yeast) 0.047
Pus7l pseudouridylate synthase 7 homolog (S. cerevisiae)-like 0.040
Heatr1 HEAT repeat containing 1 0.040
Pus1 pseudouridine synthase 1 0.040
Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 0.040
Ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.039
Brix1 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) 0.038
Ddx51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 0.037
Gtpbp4 GTP binding protein 4 0.036
Pdcd11 programmed cell death 11 0.032
Nol8 nucleolar protein 8 0.032
Igh immunoglobulin heavy chain complex 0.031
Bop1 block of proliferation 1 0.030
Vars valyl-tRNA synthetase 0.028
Dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 0.028
Gnl2 guanine nucleotide binding protein-like 2 (nucleolar) 0.027
Noc3l nucleolar complex associated 3 homolog (S. cerevisiae) 0.026
Dph2 DPH2 homolog (S. cerevisiae) 0.025
Ddx10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.025
Zfp259 zinc finger protein 259 0.025
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.025
Eif3b eukaryotic translation initiation factor 3, subunit B 0.025
Kat2a K(lysine) acetyltransferase 2A 0.025
Ddx20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.024
Ipo4 importin 4 0.022
Nop56 NOP56 ribonucleoprotein homolog (yeast) 0.022
Nolc1 nucleolar and coiled-body phosphoprotein 1 0.021
Aen apoptosis enhancing nuclease 0.020
Mki67ip Mki67 (FHA domain) interacting nucleolar phosphoprotein 0.019
Btaf1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae) 0.018
Dis3 DIS3 mitotic control homolog (S. cerevisiae) 0.018
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.018
Rbm34 RNA binding motif protein 34 0.017
Imp4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 0.017
Ino80e INO80 complex subunit E 0.016
Ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.016
Exosc10 exosome component 10 0.016
Dcaf13 DDB1 and CUL4 associated factor 13 0.016
Trp53 transformation related protein 53 0.016
Sdad1 SDA1 domain containing 1 0.016
Rrs1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.015
Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.015
Nufip1 nuclear fragile X mental retardation protein interacting protein 1 0.014
Nubp1 nucleotide binding protein 1 0.014
Atp13a1 ATPase type 13A1 0.014
Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.014
Ccar1 cell division cycle and apoptosis regulator 1 0.014
Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.013
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.013
Wdr75 WD repeat domain 75 0.013
Tomm40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.012
Dohh deoxyhypusine hydroxylase/monooxygenase 0.012
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.012
Zzz3 zinc finger, ZZ domain containing 3 0.012
Polr3a polymerase (RNA) III (DNA directed) polypeptide A 0.011
Rcl1 RNA terminal phosphate cyclase-like 1 0.011
Adrm1 adhesion regulating molecule 1 0.011
Thoc5 THO complex 5 0.011
Eif3a eukaryotic translation initiation factor 3, subunit A 0.010
Ltv1 LTV1 homolog (S. cerevisiae) 0.010
Nle1 notchless homolog 1 (Drosophila) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism