The network for 'death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

death

A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HSP82 Hsp82p 0.205
TEF4 Tef4p 0.180
SLT2 Slt2p 0.167
BMH1 Bmh1p 0.107
HYP2 Hyp2p 0.105
MSH2 Msh2p 0.099
RFC1 Rfc1p 0.093
ARB1 Arb1p 0.087
RAD3 Rad3p 0.083
RPS1A Rps1ap 0.079
DHH1 Dhh1p 0.078
SSA1 Ssa1p 0.073
RPS3 Rps3p 0.073
YAP1 Yap1p 0.070
TIF35 Tif35p 0.067
RPL10 Rpl10p 0.064
RPG1 Rpg1p 0.062
TSA1 Tsa1p 0.061
CCT6 Cct6p 0.060
TIF5 Tif5p 0.059
PRE10 Pre10p 0.059
PIL1 Pil1p 0.057
RPL19B Rpl19bp 0.057
STI1 Sti1p 0.056
SSA3 Ssa3p 0.055
CCR4 Ccr4p 0.054
AQY2 Aqy2p 0.054
CBF2 Cbf2p 0.052
YGL242C hypothetical protein 0.052
PKH2 Pkh2p 0.052
NDE1 Nde1p 0.051
DSK2 Dsk2p 0.051
RPL16B Rpl16bp 0.050
KSS1 Kss1p 0.047
CDC37 Cdc37p 0.047
RPT6 Rpt6p 0.046
VMA13 Vma13p 0.046
PIM1 Pim1p 0.046
RPS6B Rps6bp 0.045
ERB1 Erb1p 0.043
RAD54 Rad54p 0.043
SOD2 Sod2p 0.042
SAP1 Sap1p 0.042
TAF11 Taf11p 0.040
UBP9 Ubp9p 0.040
SUB2 Sub2p 0.040
SSA2 Ssa2p 0.040
MSH3 Msh3p 0.039
YHR033W hypothetical protein 0.039
TRA1 Tra1p 0.039
PRK1 Prk1p 0.039
YPK2 Ypk2p 0.038
KAR2 Kar2p 0.038
NBL1 Nbl1p 0.037
ECM29 Ecm29p 0.037
PBS2 Pbs2p 0.037
BFR1 Bfr1p 0.037
NSA1 Nsa1p 0.037
CDC55 Cdc55p 0.037
GUS1 Gus1p 0.037
CDC48 Cdc48p 0.036
MKT1 Mkt1p 0.036
SCH9 Sch9p 0.034
NUP157 Nup157p 0.034
VPS27 Vps27p 0.034
NMA111 Nma111p 0.034
RPL13A Rpl13ap 0.033
SSE1 Sse1p 0.033
SSZ1 Ssz1p 0.033
GUT2 Gut2p 0.033
GPM1 Gpm1p 0.033
SUI1 Sui1p 0.033
RPL1A Rpl1ap 0.032
ATG21 Atg21p 0.032
DNM1 Dnm1p 0.032
PPH3 Pph3p 0.032
RPS7A Rps7ap 0.032
TIM54 Tim54p 0.031
CCT3 Cct3p 0.031
YDJ1 Ydj1p 0.031
NOG2 Nog2p 0.031
ZDS2 Zds2p 0.031
STE5 Ste5p 0.030
SLI15 Sli15p 0.030
EAF3 Eaf3p 0.030
SCJ1 Scj1p 0.030
AKL1 Akl1p 0.029
NRP1 Nrp1p 0.029
MYO5 Myo5p 0.029
AHC1 Ahc1p 0.028
ATG14 Atg14p 0.028
TDH2 Tdh2p 0.028
RPL28 Rpl28p 0.028
RPT1 Rpt1p 0.028
VPS30 Vps30p 0.028
RPL32 Rpl32p 0.028
SSA4 Ssa4p 0.027
GCN20 Gcn20p 0.027
TEF2 Tef2p 0.027
SSL1 Ssl1p 0.027
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
kle-2 Protein KLE-2 0.908
hsp-1 Protein HSP-1 0.823
glp-1 Protein GLP-1 0.819
rpl-18 Protein RPL-18 0.798
crt-1 Protein CRT-1 0.761
gex-3 Protein GEX-3 0.756
mat-3 Protein MAT-3 0.734
egl-18 Protein EGL-18 0.723
atp-2 Protein ATP-2 0.721
vha-8 Protein VHA-8 0.721
ads-1 Protein ADS-1 0.712
rme-2 Protein RME-2 0.668
nud-2 Protein NUD-2 0.657
lsm-5 Protein LSM-5 0.657
vab-3 Protein VAB-3 0.651
CELE_F14E5.2 Protein F14E5.2 0.642
C28H8.3 Protein C28H8.3 0.629
tbb-2 Protein TBB-2 0.611
R10E4.1 Protein R10E4.1 0.605
egl-44 Protein EGL-44 0.602
zyg-9 Protein ZYG-9 0.592
unc-60 Protein UNC-60 0.587
ZK484.1 Protein ZK484.1 0.586
snr-1 Protein SNR-1 0.585
etr-1 Protein ETR-1 0.582
rps-0 Protein RPS-0 0.581
vha-19 Protein VHA-19 0.572
egl-46 Protein EGL-46 0.567
eftu-2 Protein EFTU-2 0.561
mut-7 Protein MUT-7 0.561
ftt-2 Protein FTT-2 0.558
egg-6 Protein EGG-6 0.557
C14C10.5 Protein C14C10.5 0.553
klp-15 Protein KLP-15 0.544
mdt-29 Protein MDT-29 0.542
icln-1 Protein ICLN-1 0.542
sta-1 Protein STA-1 0.542
rps-12 Protein RPS-12 0.540
rpl-38 Protein RPL-38 0.538
bec-1 Protein BEC-1 0.537
rme-4 Protein RME-4 0.537
dlc-1 Protein DLC-1 0.529
bub-1 Protein BUB-1 0.529
ceh-20 Protein CEH-20 0.529
pdfr-1 Protein PDFR-1 0.528
rpl-16 Protein RPL-16 0.527
unc-108 Protein UNC-108 0.521
gld-2 Protein GLD-2 0.521
rps-2 Protein RPS-2 0.521
H21P03.2 Protein H21P03.2 0.516
inx-13 Protein INX-13 0.516
gei-11 Protein GEI-11 0.514
skr-8 Protein SKR-8 0.512
tag-319 Protein TAG-319 0.508
Y71F9AL.1 Protein Y71F9AL.1 0.507
rps-4 Protein RPS-4 0.502
nmt-1 Protein NMT-1 0.499
cgr-1 Protein CGR-1 0.497
sax-7 Protein SAX-7 0.491
Y65B4BR.5 Protein Y65B4BR.5 0.490
rars-1 Protein RARS-1 0.486
rpl-5 Protein RPL-5 0.485
C53B4.4 Protein C53B4.4 0.485
F39B2.1 Protein F39B2.1 0.483
icd-1 Protein ICD-1 0.483
mua-6 Protein MUA-6 0.471
unc-9 Protein UNC-9 0.467
rpl-13 Protein RPL-13 0.466
pry-1 Protein PRY-1 0.463
ran-5 Protein RAN-5 0.460
hpo-32 Protein HPO-32 0.457
ehs-1 Protein EHS-1 0.456
gpb-2 Protein GPB-2 0.454
F18A1.7 Protein F18A1.7 0.451
exoc-7 Protein EXOC-7 0.451
acs-4 Protein ACS-4 0.450
hid-1 Protein HID-1 0.446
npp-7 Protein NPP-7 0.445
unc-120 Protein UNC-120 0.441
fbf-2 Protein FBF-2 0.435
rpa-1 Protein RPA-1 0.433
lmn-1 Protein LMN-1 0.433
nhr-2 Protein NHR-2 0.432
air-2 Protein AIR-2 0.432
W04D2.6 Protein W04D2.6 0.430
mpz-2 Protein MPZ-2 0.429
ubc-20 Protein UBC-20 0.428
rla-0 Protein RLA-0 0.427
tre-3 Protein TRE-3 0.427
cra-1 Protein CRA-1 0.425
C14B1.2 Protein C14B1.2 0.422
mrp-7 Protein MRP-7 0.422
srgp-1 Protein SRGP-1 0.421
rpl-4 Protein RPL-4 0.419
dbr-1 Protein DBR-1 0.416
K03E6.7 Protein K03E6.7 0.415
H28O16.1 Protein H28O16.1 0.413
rpl-11.1 Protein RPL-11.1 0.413
mel-26 Protein MEL-26 0.413
agef-1 Protein AGEF-1 0.413
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Danio rerio
Name Description Probability Func Analog Organism
bmp2b bone morphogenetic protein 2b 0.915
tbx1 T-box 1 0.902
fgfr1a fibroblast growth factor receptor 1a 0.783
osr1 odd-skipped related 1 (Drosophila) 0.782
shha sonic hedgehog a 0.763
runx2b runt-related transcription factor 2b 0.751
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.732
cmyb transcription factor cmyb 0.726
fgf3 fibroblast growth factor 3 0.705
gata3 GATA-binding protein 3 0.649
gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.624
bmp4 bone morphogenetic protein 4 0.598
rpsa ribosomal protein SA 0.582
gli1 GLI-Kruppel family member 1 0.545
efnb2a ephrin B2a 0.539
cct6a chaperonin containing TCP1, subunit 6A (zeta 1) 0.531
rpl18a ribosomal protein L18a 0.529
ndr2 nodal-related 2 0.521
tp63 tumor protein p63 0.511
gsc goosecoid 0.495
evpl envoplakin 0.492
rpl13 ribosomal protein L13 0.490
bbc3 BCL2 binding component 3 0.483
wnt4a wingless-type MMTV integration site family, member 4a 0.481
baxa bcl2-associated X protein, a 0.438
evx1 even-skipped homeobox 1 0.436
ctsl1a cathepsin L, 1 a 0.434
csnk1da casein kinase 1, delta a 0.427
foxo3b forkhead box O3b 0.410
rpl15 ribosomal protein L15 0.408
ptf1a pancreas specific transcription factor, 1a 0.403
boc brother of CDO 0.399
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.397
th tyrosine hydroxylase 0.396
dkk1b dickkopf 1b 0.396
ptgs2a prostaglandin-endoperoxide synthase 2a 0.392
met met proto-oncogene (hepatocyte growth factor receptor) 0.385
eif4e eukaryotic translation initiation factor 4e 0.384
kita kit receptor a 0.374
rarga retinoic acid receptor gamma a 0.371
eif3g eukaryotic translation initiation factor 3, subunit G 0.370
pcna proliferating cell nuclear antigen 0.369
faua Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a 0.354
lamb1a laminin, beta 1a 0.349
plcg1 phospholipase C, gamma 1 0.345
sgk1 serum/glucocorticoid regulated kinase 1 0.340
cct8 chaperonin containing TCP1, subunit 8 (theta) 0.336
fezf2 FEZ family zinc finger 2 0.336
etv2 ets variant gene 2 0.334
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.334
pea3 ETS-domain transcription factor pea3 0.333
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.333
dlx4a distal-less homeobox gene 4a 0.331
khdrbs1a KH domain containing, RNA binding, signal transduction associated 1a 0.331
ran ras-related nuclear protein 0.328
chd chordin 0.323
surf6 surfeit 6 0.312
tp53 tumor protein p53 0.305
dmrta2 doublesex and mab-3 related transcription factor like family A2 0.304
cnr1 cannabinoid receptor 1 0.299
dlx5a distal-less homeobox gene 5a 0.299
rpl35 ribosomal protein L35 0.295
nipblb novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila) 0.293
notch1a notch homolog 1a 0.293
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.293
gdnf glial cell derived neurotrophic factor 0.290
flncb filamin C, gamma b (actin binding protein 280) 0.290
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.289
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.286
eomesa eomesodermin homolog a 0.280
zgc:112329 zgc:112329 0.278
gpr126 G protein-coupled receptor 126 0.278
bnc2 basonuclin 2 0.278
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a 0.272
notch2 notch homolog 2 0.269
tshz1 teashirt family zinc finger 1 0.268
fabp11a fatty acid binding protein 11a 0.268
rpl7a ribosomal protein L7a 0.267
tbx20 T-box 20 0.265
pax5 paired box gene 5 0.265
hspa9 heat shock protein 9 0.263
col15a1b collagen, type XV, alpha 1b 0.262
nrg2a neuregulin 2a 0.262
sf3b4 splicing factor 3b, subunit 4 0.261
rpl19 ribosomal protein L19 0.261
col14a1 collagen, type XIV, alpha 1 0.260
alcamb activated leukocyte cell adhesion molecule b 0.259
marcksa myristoylated alanine rich protein kinase C substrate a 0.256
pkd2 polycystic kidney disease 2 0.256
lmna lamin A 0.255
gro1 groucho 1 0.254
neo1 neogenin 1 0.252
sfrp1a secreted frizzled-related protein 1a 0.248
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.248
ca8 carbonic anhydrase VIII 0.247
bcl2l1 bcl2-like 1 0.247
bmper BMP binding endothelial regulator 0.246
zgc:92237 zgc:92237 0.245
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.245
mecp2 methyl CpG binding protein 2 0.242
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Drosophila melanogaster
Name Description Probability Func Analog Organism
nej nejire 0.999
Akt1 CG4006 gene product from transcript CG4006-RA 0.988
slmb supernumerary limbs 0.976
ci cubitus interruptus 0.971
Atg1 Autophagy-specific gene 1 0.962
CG11347 CG11347 gene product from transcript CG11347-RE 0.949
Ras85D Ras oncogene at 85D 0.946
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.938
put punt 0.931
kay kayak 0.926
pnt pointed 0.926
lola longitudinals lacking 0.914
tkv thickveins 0.912
shn schnurri 0.901
hep hemipterous 0.894
Pak PAK-kinase 0.891
drpr draper 0.889
E(z) Enhancer of zeste 0.887
eff effete 0.880
Caps Calcium activated protein for secretion 0.864
crol crooked legs 0.843
milt milton 0.839
shi shibire 0.829
numb CG3779 gene product from transcript CG3779-RB 0.827
eIF-4a Eukaryotic initiation factor 4a 0.824
zip zipper 0.820
dom domino 0.819
EcR Ecdysone receptor 0.816
InR Insulin-like receptor 0.798
shg shotgun 0.789
Fmr1 CG6203 gene product from transcript CG6203-RC 0.788
Pka-C1 cAMP-dependent protein kinase 1 0.787
shot short stop 0.779
debcl death executioner Bcl-2 homologue 0.775
Atg18 Autophagy-specific gene 18 0.775
skpA CG16983 gene product from transcript CG16983-RD 0.769
CycG Cyclin G 0.761
Rac1 CG2248 gene product from transcript CG2248-RA 0.755
dac dachshund 0.749
rap retina aberrant in pattern 0.747
Eip93F CG18389 gene product from transcript CG18389-RB 0.743
Egfr Epidermal growth factor receptor 0.739
p53 CG33336 gene product from transcript CG33336-RB 0.736
Eip74EF Ecdysone-induced protein 74EF 0.736
Pvr PDGF- and VEGF-receptor related 0.734
phl pole hole 0.723
scny scrawny 0.722
Rho1 CG8416 gene product from transcript CG8416-RB 0.717
jing CG9397 gene product from transcript CG9397-RI 0.703
ago archipelago 0.695
drk downstream of receptor kinase 0.694
dm diminutive 0.693
Pi3K21B CG2699 gene product from transcript CG2699-RA 0.693
CG7998 CG7998 gene product from transcript CG7998-RA 0.684
Mad Mothers against dpp 0.674
Dad Daughters against dpp 0.671
Gyc76C Guanylyl cyclase at 76C 0.670
Rbf Retinoblastoma-family protein 0.665
Rel Relish 0.665
dally division abnormally delayed 0.664
mrn marionette 0.664
jar jaguar 0.661
spas spastin 0.658
tlk Tousled-like kinase 0.654
sax saxophone 0.649
arm armadillo 0.648
nub nubbin 0.648
Hsp83 Heat shock protein 83 0.643
eIF-4E Eukaryotic initiation factor 4E 0.642
bif bifocal 0.636
Pten CG5671 gene product from transcript CG5671-RB 0.628
sim single-minded 0.624
bel belle 0.624
Atpalpha Na pump alpha subunit 0.623
S6k RPS6-p70-protein kinase 0.623
sd scalloped 0.623
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.622
Trxr-1 Thioredoxin reductase-1 0.609
Ef2b Elongation factor 2b 0.607
Aos1 CG12276 gene product from transcript CG12276-RA 0.602
RpL7A Ribosomal protein L7A 0.596
bcd bicoid 0.593
G-salpha60A G protein salpha 60A 0.592
CkIIalpha Casein kinase II alpha subunit 0.588
p120ctn Adherens junction protein p120 0.585
CG5794 CG5794 gene product from transcript CG5794-RB 0.583
endoA endophilin A 0.574
alpha-Cat alpha Catenin 0.568
ush u-shaped 0.567
stck steamer duck 0.563
sop string of pearls 0.558
p38b CG7393 gene product from transcript CG7393-RA 0.557
Scm Sex comb on midleg 0.545
MAGE CG10059 gene product from transcript CG10059-RA 0.540
RpL9 Ribosomal protein L9 0.538
Atg8a Autophagy-specific gene 8a 0.537
Mov34 CG3416 gene product from transcript CG3416-RA 0.536
CycA Cyclin A 0.531
CkIalpha Casein kinase Ialpha 0.530
Moe Moesin 0.529
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism