IMP
Process View
The network for 'attachment of mitotic spindle microtubules to kinetochore' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
attachment of mitotic spindle microtubules to kinetochore
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during mitosis. During mitosis, the kinetochores of sister chromosomes are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| MTW1 | Mtw1p | 0.083 | |
| SLI15 | Sli15p | 0.070 | |
| TID3 | Tid3p | 0.057 | |
| DSN1 | Dsn1p | 0.050 | |
| KIP1 | Kip1p | 0.041 | |
| NUF2 | Nuf2p | 0.038 | |
| MIF2 | Mif2p | 0.037 | |
| SLK19 | Slk19p | 0.036 | |
| NSL1 | Nsl1p | 0.035 | |
| IPL1 | Ipl1p | 0.032 | |
| SPC24 | Spc24p | 0.027 | |
| SMC4 | Smc4p | 0.027 | |
| CTF3 | Ctf3p | 0.025 | |
| CIN8 | Cin8p | 0.025 | |
| NBL1 | Nbl1p | 0.023 | |
| SPC105 | Spc105p | 0.022 | |
| NNF1 | Nnf1p | 0.021 | |
| MAD1 | Mad1p | 0.020 | |
| PPH21 | Pph21p | 0.020 | |
| MPS1 | Mps1p | 0.020 | |
| STU1 | Stu1p | 0.018 | |
| CSE4 | Cse4p | 0.018 | |
| BRN1 | Brn1p | 0.018 | |
| PPH22 | Pph22p | 0.015 | |
| OKP1 | Okp1p | 0.014 | |
| DAM1 | Dam1p | 0.013 | |
| CHL1 | Chl1p | 0.013 | |
| MAD2 | Mad2p | 0.013 | |
| SPC25 | Spc25p | 0.013 | |
| VIK1 | Vik1p | 0.012 | |
| SMC2 | Smc2p | 0.012 | |
| KAR3 | Kar3p | 0.011 | |
| YBP2 | Ybp2p | 0.011 |
Loading network...
Caenorhabditis elegans
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| gpr-1 | Protein GPR-1 | 0.540 | |
| mcm-7 | Protein MCM-7 | 0.490 | |
| aspm-1 | Protein ASPM-1 | 0.425 | |
| knl-1 | Protein KNL-1 | 0.415 | |
| klp-19 | Protein KLP-19 | 0.222 | |
| bub-1 | Protein BUB-1 | 0.178 | |
| F54E12.2 | Protein F54E12.2 | 0.171 | |
| rnr-1 | Protein RNR-1 | 0.124 | |
| mcm-6 | Protein MCM-6 | 0.120 | |
| mel-28 | Protein MEL-28 | 0.118 | |
| lin-13 | Protein LIN-13 | 0.109 | |
| top-2 | Protein TOP-2 | 0.106 | |
| CELE_F59A6.5 | Protein F59A6.5 | 0.103 | |
| smc-4 | Protein SMC-4 | 0.099 | |
| hcp-4 | Protein HCP-4 | 0.093 | |
| cls-2 | Protein CLS-2 | 0.087 | |
| hcp-2 | Protein HCP-2 | 0.079 | |
| T07C4.10 | Protein T07C4.10 | 0.067 | |
| CELE_Y53F4B.9 | Protein Y53F4B.9 | 0.066 | |
| scc-1 | Protein SCC-1 | 0.064 | |
| gpr-2 | Protein GPR-2 | 0.059 | |
| smc-5 | Protein SMC-5 | 0.055 | |
| F11E6.7 | Protein F11E6.7 | 0.055 | |
| cin-4 | Protein CIN-4 | 0.047 | |
| him-10 | Protein HIM-10 | 0.046 | |
| F33H2.5 | Protein F33H2.5 | 0.041 | |
| clp-2 | Protein CLP-2 | 0.041 | |
| CELE_C39E9.12 | Protein C39E9.12 | 0.040 | |
| Y47D3A.29 | Protein Y47D3A.29 | 0.039 | |
| bmk-1 | Protein BMK-1 | 0.033 | |
| ttm-4 | Protein TTM-4 | 0.032 | |
| prp-8 | Protein PRP-8 | 0.032 | |
| hcp-6 | Protein HCP-6 | 0.032 | |
| M03C11.8 | Protein M03C11.8 | 0.032 | |
| ruvb-2 | Protein RUVB-2 | 0.031 | |
| R05D3.2 | Protein R05D3.2 | 0.031 | |
| mcm-3 | Protein MCM-3 | 0.030 | |
| F22G12.5 | Protein F22G12.5 | 0.027 | |
| grp-1 | Protein GRP-1 | 0.026 | |
| T24H10.1 | Protein T24H10.1 | 0.026 | |
| let-858 | Protein LET-858 | 0.022 | |
| zyg-9 | Protein ZYG-9 | 0.021 | |
| isw-1 | Protein ISW-1 | 0.021 | |
| tbb-1 | Protein TBB-1 | 0.021 | |
| inft-2 | Protein INFT-2 | 0.020 | |
| knl-2 | Protein KNL-2 | 0.019 | |
| rpl-11.1 | Protein RPL-11.1 | 0.019 | |
| atl-1 | Protein ATL-1 | 0.018 | |
| msh-2 | Protein MSH-2 | 0.018 | |
| cye-1 | Protein CYE-1 | 0.017 | |
| pis-1 | Protein PIS-1 | 0.017 | |
| W02B8.2 | Protein W02B8.2 | 0.017 | |
| acs-4 | Protein ACS-4 | 0.016 | |
| T08A11.2 | Protein T08A11.2 | 0.016 | |
| ima-3 | Protein IMA-3 | 0.015 | |
| rpn-1 | Protein RPN-1 | 0.014 | |
| szy-20 | Protein SZY-20 | 0.014 | |
| sas-4 | Protein SAS-4 | 0.014 | |
| set-16 | Protein SET-16 | 0.013 | |
| swsn-2.1 | Protein SWSN-2.1 | 0.013 | |
| CELE_F19F10.9 | Protein F19F10.9 | 0.013 | |
| Y4C6B.1 | Protein Y4C6B.1 | 0.013 | |
| syn-16 | Protein SYN-16 | 0.012 | |
| clpf-1 | Protein CLPF-1 | 0.012 | |
| lmn-1 | Protein LMN-1 | 0.012 | |
| ZK418.9 | Protein ZK418.9 | 0.012 | |
| wrm-1 | Protein WRM-1 | 0.012 | |
| unc-59 | Protein UNC-59 | 0.012 | |
| F25H5.5 | Protein F25H5.5 | 0.011 | |
| zwl-1 | Protein ZWL-1 | 0.011 | |
| ndc-80 | Protein NDC-80 | 0.011 | |
| mars-1 | Protein MARS-1 | 0.011 | |
| taf-2 | Protein TAF-2 | 0.011 | |
| rrf-3 | Protein RRF-3 | 0.010 | |
| CELE_F23C8.9 | Protein F23C8.9 | 0.010 | |
| tbb-2 | Protein TBB-2 | 0.010 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| NUP133 | nucleoporin 133kDa | 0.712 | |
| CENPE | centromere protein E, 312kDa | 0.491 | |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.413 | |
| SMC2 | structural maintenance of chromosomes 2 | 0.400 | |
| NUF2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.274 | |
| NCAPG | non-SMC condensin I complex, subunit G | 0.262 | |
| SMC4 | structural maintenance of chromosomes 4 | 0.238 | |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.217 | |
| KIF14 | kinesin family member 14 | 0.163 | |
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.148 | |
| FANCI | Fanconi anemia, complementation group I | 0.137 | |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.124 | |
| KIF23 | kinesin family member 23 | 0.114 | |
| ECT2 | epithelial cell transforming sequence 2 oncogene | 0.109 | |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.107 | |
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.087 | |
| NCAPH2 | non-SMC condensin II complex, subunit H2 | 0.073 | |
| LBR | lamin B receptor | 0.069 | |
| KIF1B | kinesin family member 1B | 0.068 | |
| RACGAP1 | Rac GTPase activating protein 1 | 0.067 | |
| NCAPH | non-SMC condensin I complex, subunit H | 0.065 | |
| KIF15 | kinesin family member 15 | 0.061 | |
| RBBP8 | retinoblastoma binding protein 8 | 0.057 | |
| PHAX | phosphorylated adaptor for RNA export | 0.055 | |
| KIF18A | kinesin family member 18A | 0.055 | |
| MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.055 | |
| DEPDC1 | DEP domain containing 1 | 0.055 | |
| ZWINT | ZW10 interactor | 0.053 | |
| VCP | valosin containing protein | 0.052 | |
| TMEM194A | transmembrane protein 194A | 0.051 | |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.050 | |
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.049 | |
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.047 | |
| AKAP9 | A kinase (PRKA) anchor protein (yotiao) 9 | 0.045 | |
| GPSM2 | G-protein signaling modulator 2 | 0.044 | |
| UBXN2A | UBX domain protein 2A | 0.043 | |
| SGOL2 | shugoshin-like 2 (S. pombe) | 0.042 | |
| SASS6 | spindle assembly 6 homolog (C. elegans) | 0.039 | |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.037 | |
| SPC25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.037 | |
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.034 | |
| PRC1 | protein regulator of cytokinesis 1 | 0.034 | |
| ATXN3 | ataxin 3 | 0.032 | |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.032 | |
| E2F5 | E2F transcription factor 5, p130-binding | 0.031 | |
| LIN52 | lin-52 homolog (C. elegans) | 0.030 | |
| CASC5 | cancer susceptibility candidate 5 | 0.030 | |
| MIS18BP1 | MIS18 binding protein 1 | 0.029 | |
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.029 | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.029 | |
| LIN54 | lin-54 homolog (C. elegans) | 0.028 | |
| STIL | SCL/TAL1 interrupting locus | 0.028 | |
| ANLN | anillin, actin binding protein | 0.026 | |
| TTF2 | transcription termination factor, RNA polymerase II | 0.024 | |
| KIF11 | kinesin family member 11 | 0.024 | |
| HELLS | helicase, lymphoid-specific | 0.024 | |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 0.024 | |
| CEP55 | centrosomal protein 55kDa | 0.024 | |
| KIF20B | kinesin family member 20B | 0.024 | |
| RBL2 | retinoblastoma-like 2 (p130) | 0.022 | |
| GEN1 | Gen homolog 1, endonuclease (Drosophila) | 0.022 | |
| DSN1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.022 | |
| AMFR | autocrine motility factor receptor | 0.021 | |
| CEP152 | centrosomal protein 152kDa | 0.021 | |
| NSL1 | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.021 | |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.021 | |
| TTK | TTK protein kinase | 0.020 | |
| C12orf48 | chromosome 12 open reading frame 48 | 0.020 | |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.020 | |
| OR5AR1 | olfactory receptor, family 5, subfamily AR, member 1 | 0.019 | |
| DNA2 | DNA replication helicase 2 homolog (yeast) | 0.019 | |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.019 | |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.019 | |
| CCNE2 | cyclin E2 | 0.018 | |
| TROAP | trophinin associated protein (tastin) | 0.018 | |
| CENPQ | centromere protein Q | 0.018 | |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 | 0.017 | |
| CDC7 | cell division cycle 7 homolog (S. cerevisiae) | 0.016 | |
| C1orf109 | chromosome 1 open reading frame 109 | 0.016 | |
| MELK | maternal embryonic leucine zipper kinase | 0.015 | |
| KIF20A | kinesin family member 20A | 0.014 | |
| CCDC138 | coiled-coil domain containing 138 | 0.014 | |
| ZW10 | ZW10, kinetochore associated, homolog (Drosophila) | 0.014 | |
| RBL1 | retinoblastoma-like 1 (p107) | 0.013 | |
| ANAPC7 | anaphase promoting complex subunit 7 | 0.013 | |
| WDR67 | WD repeat domain 67 | 0.013 | |
| SMC1A | structural maintenance of chromosomes 1A | 0.013 | |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.013 | |
| TTI1 | Tel2 interacting protein 1 homolog (S. pombe) | 0.013 | |
| CENPI | centromere protein I | 0.013 | |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.013 | |
| PLK4 | polo-like kinase 4 | 0.013 | |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.012 | |
| CBX5 | chromobox homolog 5 | 0.012 | |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.012 | |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.012 | |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.011 | |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.011 | |
| CREBBP | CREB binding protein | 0.011 | |
| NUP107 | nucleoporin 107kDa | 0.011 |