The network for 'response to temperature stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to temperature stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HSP42 Hsp42p 0.817
CLA4 Cla4p 0.672
PBS2 Pbs2p 0.527
STI1 Sti1p 0.495
ROM2 Rom2p 0.450
SSA4 Ssa4p 0.423
BTN2 Btn2p 0.423
MOB1 Mob1p 0.405
YDJ1 Ydj1p 0.363
HSP104 Hsp104p 0.358
GLN3 Gln3p 0.339
AHA1 Aha1p 0.333
SSE1 Sse1p 0.317
CTI6 Cti6p 0.315
CPR6 Cpr6p 0.289
SIN3 Sin3p 0.275
SSK1 Ssk1p 0.275
NUP116 Nup116p 0.214
STE5 Ste5p 0.208
NUP170 Nup170p 0.206
RPN4 Rpn4p 0.206
BOI1 Boi1p 0.204
GIS1 Gis1p 0.203
SCH9 Sch9p 0.195
ATG32 Atg32p 0.193
SSK2 Ssk2p 0.186
NTO1 Nto1p 0.174
RIM101 Rim101p 0.169
BUR6 Bur6p 0.159
NUP100 Nup100p 0.159
MIG2 Mig2p 0.157
NUP120 Nup120p 0.155
SYP1 Syp1p 0.151
SSE2 Sse2p 0.138
HCH1 Hch1p 0.133
NBP2 Nbp2p 0.132
PPZ1 Ppz1p 0.127
NUP145 Nup145p 0.126
GIP2 Gip2p 0.124
RXT2 Rxt2p 0.124
FES1 Fes1p 0.116
SSA2 Ssa2p 0.115
NUP157 Nup157p 0.112
CSR2 Csr2p 0.112
CUP9 Cup9p 0.107
TSL1 Tsl1p 0.106
RPO21 Rpo21p 0.105
FZO1 Fzo1p 0.104
HSP78 Hsp78p 0.103
UFD2 Ufd2p 0.102
TIF4631 Tif4631p 0.102
NUP49 Nup49p 0.100
SNF1 Snf1p 0.100
MIG3 Mig3p 0.094
CRZ1 Crz1p 0.094
SUI3 Sui3p 0.093
SAP30 Sap30p 0.090
UGP1 Ugp1p 0.090
CTK3 Ctk3p 0.088
RXT3 Rxt3p 0.087
OPY2 Opy2p 0.087
BBC1 Bbc1p 0.086
CDC4 Cdc4p 0.084
CNB1 Cnb1p 0.084
MSC1 Msc1p 0.084
EHT1 Eht1p 0.083
MOT3 Mot3p 0.083
ASH1 Ash1p 0.083
BCK1 Bck1p 0.083
HSP31 Hsp31p 0.082
RAS2 Ras2p 0.082
RLM1 Rlm1p 0.082
CDC25 Cdc25p 0.081
URA2 Ura2p 0.079
CSE1 Cse1p 0.079
NAP1 Nap1p 0.079
POM34 Pom34p 0.079
SHE4 She4p 0.079
SUI2 Sui2p 0.078
MDM32 Mdm32p 0.076
TPK2 Tpk2p 0.075
RIM4 Rim4p 0.074
TPS1 Tps1p 0.074
MBR1 Mbr1p 0.074
SIS1 Sis1p 0.073
GAC1 Gac1p 0.073
CNA1 Cna1p 0.073
KEM1 Kem1p 0.072
LRE1 Lre1p 0.072
SUR1 Sur1p 0.071
RPB11 Rpb11p 0.071
VAC7 Vac7p 0.071
HSF1 Hsf1p 0.070
IMD3 Imd3p 0.069
THP2 Thp2p 0.069
SSA1 Ssa1p 0.068
IQG1 Iqg1p 0.068
GND2 Gnd2p 0.067
ARP8 Arp8p 0.067
SUB2 Sub2p 0.067
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
hsp-16.2 Protein HSP-16.2 0.434
hsp-70 Protein HSP-70 0.383
hsp-16.41 Protein HSP-16.41 0.382
hsp-16.1 Protein HSP-16.1 0.241
vab-3 Protein VAB-3 0.225
ZC449.5 Protein ZC449.5 0.211
cat-1 Protein CAT-1 0.203
F44E5.4 Protein F44E5.4 0.171
mpk-1 Protein MPK-1 0.168
hsp-16.48 Protein HSP-16.48 0.161
pal-1 Protein PAL-1 0.121
nhr-17 Protein NHR-17 0.116
itr-1 Protein ITR-1 0.106
goa-1 Protein GOA-1 0.091
egal-1 Protein EGAL-1 0.090
vav-1 Protein VAV-1 0.088
unc-9 Protein UNC-9 0.084
daf-11 Protein DAF-11 0.080
zfp-1 Protein ZFP-1 0.080
unc-43 Protein UNC-43 0.077
aph-2 Protein APH-2 0.075
tax-2 Protein TAX-2 0.074
osm-6 Protein OSM-6 0.071
arf-1.2 Protein ARF-1.2 0.070
unc-18 Protein UNC-18 0.067
unc-62 Protein UNC-62 0.064
sca-1 Protein SCA-1 0.061
nhr-67 Protein NHR-67 0.060
paqr-1 Protein PAQR-1 0.058
tax-6 Protein TAX-6 0.057
ncam-1 Protein NCAM-1 0.055
CELE_F55C5.8 Protein F55C5.8 0.055
cpn-1 Protein CPN-1 0.053
CELE_H28G03.1 Protein H28G03.1 0.051
par-3 Protein PAR-3 0.051
ipp-5 Protein IPP-5 0.050
sax-7 Protein SAX-7 0.050
rsks-1 Protein RSKS-1 0.050
svh-2 Protein SVH-2 0.050
dnj-12 Protein DNJ-12 0.050
unc-32 Protein UNC-32 0.050
kin-29 Protein KIN-29 0.049
inx-1 Protein INX-1 0.049
F58B3.6 Protein F58B3.6 0.049
soc-2 Protein SOC-2 0.049
F35F11.1 Protein F35F11.1 0.047
R05F9.6 Protein R05F9.6 0.046
F28B4.3 Protein F28B4.3 0.045
ugt-22 Protein UGT-22 0.045
pup-2 Protein PUP-2 0.044
apl-1 Protein APL-1 0.044
mat-3 Protein MAT-3 0.044
R166.2 Protein R166.2 0.044
egl-8 Protein EGL-8 0.044
mig-15 Protein MIG-15 0.043
unc-36 Protein UNC-36 0.043
rgs-7 Protein RGS-7 0.042
nhr-34 Protein NHR-34 0.042
unc-42 Protein UNC-42 0.042
rab-1 Protein RAB-1 0.041
rfp-1 Protein RFP-1 0.041
zip-7 Protein ZIP-7 0.041
odr-1 Protein ODR-1 0.041
tag-53 Protein TAG-53 0.040
pes-7 Protein PES-7 0.040
sos-1 Protein SOS-1 0.040
C10E2.6 Protein C10E2.6 0.040
hsp-4 Protein HSP-4 0.039
pgp-5 Protein PGP-5 0.039
hot-2 Protein HOT-2 0.039
prp-8 Protein PRP-8 0.039
pkg-1 Protein PKG-1 0.039
F31D4.2 Protein F31D4.2 0.039
rpl-16 Protein RPL-16 0.038
atg-2 Protein ATG-2 0.038
tag-320 Protein TAG-320 0.038
eat-4 Protein EAT-4 0.038
plc-1 Protein PLC-1 0.038
M57.2 Protein M57.2 0.038
rab-5 Protein RAB-5 0.037
M03F8.3 Protein M03F8.3 0.037
pct-1 Protein PCT-1 0.037
egg-6 Protein EGG-6 0.037
sec-8 Protein SEC-8 0.036
atx-2 Protein ATX-2 0.036
vab-10 Protein VAB-10 0.036
dmd-7 Protein DMD-7 0.036
ain-1 Protein AIN-1 0.036
C09G1.4 Protein C09G1.4 0.036
cdc-42 Protein CDC-42 0.036
par-1 Protein PAR-1 0.035
dnj-19 Protein DNJ-19 0.035
vpr-1 Protein VPR-1 0.035
mca-3 Protein MCA-3 0.035
rps-1 Protein RPS-1 0.035
C36E8.1 Protein C36E8.1 0.035
K06A9.1 Protein K06A9.1 0.035
capg-2 Protein CAPG-2 0.034
rps-27 Protein RPS-27 0.034
T03G11.6 Protein T03G11.6 0.034
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cry3 cryptochrome 3 0.623
hspa5 heat shock protein 5 0.588
atf3 activating transcription factor 3 0.420
per2 period homolog 2 (Drosophila) 0.390
hsp90a.2 heat shock protein 90-alpha 2 0.387
spry4 sprouty (Drosophila) homolog 4 0.292
glra1 glycine receptor, alpha 1 0.269
epas1b endothelial PAS domain protein 1b 0.261
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.225
th2 tyrosine hydroxylase 2 0.222
cry2b cryptochrome 2b 0.215
qk quaking 0.209
tardbp TAR DNA binding protein 0.205
trpa1b transient receptor potential cation channel, subfamily A, member 1b 0.180
calrl calreticulin like 0.172
adrb2a adrenergic receptor, beta 2a 0.168
nf1a neurofibromin 1a 0.164
ncl nucleolin 0.161
cry1a cryptochrome 1a 0.160
atp1b1b ATPase, Na+/K+ transporting, beta 1b polypeptide 0.159
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.158
wnt10a wingless-type MMTV integration site family, member 10a 0.128
egr1 early growth response 1 0.123
pdip5 protein disulfide isomerase-related protein (provisional) 0.120
gpia glucose phosphate isomerase a 0.116
junb jun B proto-oncogene 0.116
igfbp1b insulin-like growth factor binding protein 1b 0.115
gadd45aa growth arrest and DNA-damage-inducible, alpha, a 0.114
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.110
ef1a elongation factor 1-alpha 0.109
opn4x1 opsin 4x1 0.103
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.103
psen1 presenilin 1 0.099
aldocb aldolase C, fructose-bisphosphate, b 0.095
dag1 dystroglycan 1 0.093
opn1sw1 opsin 1 (cone pigments), short-wave-sensitive 1 0.088
sae1 SUMO1 activating enzyme subunit 1 0.087
bbc3 BCL2 binding component 3 0.086
pcna proliferating cell nuclear antigen 0.085
cat catalase 0.085
pdia3 protein disulfide isomerase family A, member 3 0.084
igf1rb insulin-like growth factor 1b receptor 0.082
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.080
cdkrap3 CDK5 regulatory subunit associated protein 3 0.079
prox2 prospero homeobox 2 0.079
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.074
foxo3b forkhead box O3b 0.074
lass2 LAG1 homolog, ceramide synthase 2 (S. cerevisiae) 0.073
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.068
setb SET translocation (myeloid leukemia-associated) B 0.068
sgk1 serum/glucocorticoid regulated kinase 1 0.067
efnb2a ephrin B2a 0.067
p2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.066
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.065
znf395b zinc finger protein 395b 0.064
hsp70l heat shock cognate 70-kd protein, like 0.064
si:rp71-39b20.7 si:rp71-39b20.7 0.062
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.060
copeb core promoter element binding protein 0.059
pdia4 protein disulfide isomerase associated 4 0.057
manf mesencephalic astrocyte-derived neurotrophic factor 0.057
smyhc1 slow myosin heavy chain 1 0.056
ptprf protein tyrosine phosphatase, receptor type, F 0.056
prmt1 protein arginine methyltransferase 1 0.056
fgfr1a fibroblast growth factor receptor 1a 0.055
jun jun proto-oncogene 0.054
hmgb1b high-mobility group box 1b 0.054
entpd3 ectonucleoside triphosphate diphosphohydrolase 3 0.053
tp73 tumor protein p73 0.052
neurod neurogenic differentiation 0.050
atp1b1a ATPase, Na+/K+ transporting, beta 1a polypeptide 0.050
otx1b orthodenticle homolog 1b 0.050
slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.049
col14a1 collagen, type XIV, alpha 1 0.049
si:dkey-228g21.4 si:dkey-228g21.4 0.049
irf9 interferon regulatory factor 9 0.048
fas Fas (TNF receptor superfamily, member 6) 0.048
tubb2c tubulin, beta 2c 0.048
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.045
bmp4 bone morphogenetic protein 4 0.044
bactin2 bactin2 0.044
myf6 myogenic factor 6 0.044
bsk146 brain specific kinase 146 0.044
rag1 recombination activating gene 1 0.043
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.043
sod1 superoxide dismutase 1, soluble 0.043
gnat2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.042
ppia peptidylprolyl isomerase A (cyclophilin A) 0.041
zgc:171872 zgc:171872 0.041
lama2 laminin, alpha 2 0.040
agr2 anterior gradient homolog 2 (Xenopus laevis) 0.040
epo erythropoietin 0.040
kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.039
nr1d1 nuclear receptor subfamily 1, group d, member 1 0.039
runx1 runt-related transcription factor 1 0.038
eny2 enhancer of yellow 2 homolog (Drosophila) 0.038
tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) 0.038
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.038
atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide 0.037
ncam1b neural cell adhesion molecule 1b 0.037
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
GstD1 Glutathione S transferase D1 0.950
Hsp68 Heat shock protein 68 0.888
GstE6 Glutathione S transferase E6 0.877
shi shibire 0.853
Hsp70Ab Heat-shock-protein-70Ab 0.791
sgg shaggy 0.779
GstE7 Glutathione S transferase E7 0.723
Ace Acetylcholine esterase 0.710
slo slowpoke 0.705
norpA no receptor potential A 0.695
stv starvin 0.648
tipE temperature-induced paralytic E 0.643
CG11347 CG11347 gene product from transcript CG11347-RE 0.638
5-HT1A Serotonin receptor 1A 0.626
Hsp70Aa Heat-shock-protein-70Aa 0.606
Tbh Tyramine beta hydroxylase 0.575
Pka-C1 cAMP-dependent protein kinase 1 0.568
Arr2 Arrestin 2 0.564
rdgC retinal degeneration C 0.552
GstD5 Glutathione S transferase D5 0.550
G-salpha60A G protein salpha 60A 0.532
btv beethoven 0.524
na narrow abdomen 0.508
Ras85D Ras oncogene at 85D 0.497
Hsp70Bc Heat-shock-protein-70Bc 0.497
Hsp26 Heat shock protein 26 0.487
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.475
Ugt35a UDP-glycosyltransferase 35a 0.468
CG10911 CG10911 gene product from transcript CG10911-RA 0.466
Fmr1 CG6203 gene product from transcript CG6203-RC 0.461
Hsp23 Heat shock protein 23 0.459
CG6283 CG6283 gene product from transcript CG6283-RA 0.455
Cat Catalase 0.455
ppk pickpocket 0.451
fru fruitless 0.433
NLaz Neural Lazarillo 0.430
dnc dunce 0.426
rut rutabaga 0.403
nonA no on or off transient A 0.400
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.378
Hsp27 Heat shock protein 27 0.368
CG13568 CG13568 gene product from transcript CG13568-RG 0.364
Nf1 Neurofibromin 1 0.350
drpr draper 0.349
Rac1 CG2248 gene product from transcript CG2248-RA 0.347
Nlp Nucleoplasmin 0.347
TrpA1 Transient receptor potential A1 0.317
Csp Cysteine string protein 0.305
Nmdar1 NMDA receptor 1 0.291
cpx complexin 0.287
Tre Trehalose-sensitivity 0.282
Hsp70Bb Heat-shock-protein-70Bb 0.280
myoglianin CG1838 gene product from transcript CG1838-RD 0.279
scb scab 0.279
LvpH Larval visceral protein H 0.272
pain painless 0.271
CG14933 CG14933 gene product from transcript CG14933-RA 0.261
bsk basket 0.259
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.257
CG14634 CG14634 gene product from transcript CG14634-RB 0.256
Adh Alcohol dehydrogenase 0.255
nos nanos 0.255
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.247
Fps85D Fps oncogene analog 0.246
inaD inactivation no afterpotential D 0.246
stnA stoned A 0.245
Trx-2 thioredoxin-2 0.240
CG42629 CG42629 gene product from transcript CG42629-RB 0.240
Galpha49B G protein alpha49B 0.240
Parg Poly(ADP-ribose) glycohydrolase 0.237
Thor CG8846 gene product from transcript CG8846-RA 0.237
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.228
ple pale 0.227
CG10550 CG10550 gene product from transcript CG10550-RB 0.219
Tao-1 CG14217 gene product from transcript CG14217-RF 0.219
Parp Poly-(ADP-ribose) polymerase 0.218
Rdl Resistant to dieldrin 0.213
trx trithorax 0.212
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.211
Hsp70Ba Heat-shock-protein-70Ba 0.205
laza lazaro 0.200
foxo forkhead box, sub-group O 0.198
Rh6 Rhodopsin 6 0.198
unc-13 CG2999 gene product from transcript CG2999-RA 0.197
LamC Lamin C 0.194
amn amnesiac 0.193
E23 Early gene at 23 0.193
stai stathmin 0.192
Hsp22 Heat shock protein 22 0.192
ninaE neither inactivation nor afterpotential E 0.189
Ork1 Open rectifier K[+] channel 1 0.188
krz kurtz 0.187
bel belle 0.184
cdm cadmus 0.182
CG9796 CG9796 gene product from transcript CG9796-RA 0.181
alphaTry alphaTrypsin 0.179
CG30069 CG30069 gene product from transcript CG30069-RA 0.178
CG9472 CG9472 gene product from transcript CG9472-RA 0.173
mav maverick 0.170
CG12672 CG12672 gene product from transcript CG12672-RA 0.170
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.990
HSPB8 heat shock 22kDa protein 8 0.959
CRYAB crystallin, alpha B 0.943
HSPA8 heat shock 70kDa protein 8 0.911
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.902
BAG3 BCL2-associated athanogene 3 0.847
MAPK8 mitogen-activated protein kinase 8 0.777
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.708
JUN jun proto-oncogene 0.696
FGFR2 fibroblast growth factor receptor 2 0.605
RB1 retinoblastoma 1 0.567
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.559
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.491
HSPA1B heat shock 70kDa protein 1B 0.403
HSPH1 heat shock 105kDa/110kDa protein 1 0.402
HSPB1 heat shock 27kDa protein 1 0.380
TP53 tumor protein p53 0.356
FKBP4 FK506 binding protein 4, 59kDa 0.316
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.313
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.308
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.305
FGFR1 fibroblast growth factor receptor 1 0.301
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.294
IL1B interleukin 1, beta 0.284
ATF2 activating transcription factor 2 0.269
MAP2K4 mitogen-activated protein kinase kinase 4 0.228
HSPA1A heat shock 70kDa protein 1A 0.225
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.206
MAPK1 mitogen-activated protein kinase 1 0.203
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 0.189
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.186
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.181
APP amyloid beta (A4) precursor protein 0.176
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.159
MAPK14 mitogen-activated protein kinase 14 0.150
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.135
RPLP1 ribosomal protein, large, P1 0.132
CXCL3 chemokine (C-X-C motif) ligand 3 0.127
PPID peptidylprolyl isomerase D 0.118
CDK9 cyclin-dependent kinase 9 0.116
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.115
UBC ubiquitin C 0.113
ATF3 activating transcription factor 3 0.113
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.111
RBBP4 retinoblastoma binding protein 4 0.110
DUSP1 dual specificity phosphatase 1 0.110
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.107
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.106
IL8 interleukin 8 0.100
RPS3A ribosomal protein S3A 0.100
C2orf65 chromosome 2 open reading frame 65 0.099
RPS24 ribosomal protein S24 0.092
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.092
ARRB1 arrestin, beta 1 0.090
FGF10 fibroblast growth factor 10 0.087
BAG2 BCL2-associated athanogene 2 0.086
STIP1 stress-induced-phosphoprotein 1 0.081
LRRK2 leucine-rich repeat kinase 2 0.079
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.078
NOSTRIN nitric oxide synthase trafficker 0.077
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.077
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.077
CRYGC crystallin, gamma C 0.066
IGF1R insulin-like growth factor 1 receptor 0.066
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.066
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.064
ARRB2 arrestin, beta 2 0.063
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.063
EGFR epidermal growth factor receptor 0.062
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.062
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.062
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.060
CXCL2 chemokine (C-X-C motif) ligand 2 0.060
PDIA6 protein disulfide isomerase family A, member 6 0.060
THOC5 THO complex 5 0.058
CALB1 calbindin 1, 28kDa 0.058
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.057
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.057
HSPB2 heat shock 27kDa protein 2 0.055
GCLM glutamate-cysteine ligase, modifier subunit 0.054
CRYBB2 crystallin, beta B2 0.054
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.054
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.052
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.052
HDAC1 histone deacetylase 1 0.052
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.052
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.050
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.047
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.047
RPS23 ribosomal protein S23 0.045
PPP5C protein phosphatase 5, catalytic subunit 0.044
BAG1 BCL2-associated athanogene 0.042
SIRT1 sirtuin 1 0.042
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.042
PARP1 poly (ADP-ribose) polymerase 1 0.041
THOC1 THO complex 1 0.040
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.040
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.040
HNRPDL heterogeneous nuclear ribonucleoprotein D-like 0.039
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.038
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 0.787
Nos1 nitric oxide synthase 1, neuronal 0.764
Lepr leptin receptor 0.707
Per2 period homolog 2 (Drosophila) 0.619
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.574
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.574
Cry2 cryptochrome 2 (photolyase-like) 0.527
Pnpla2 patatin-like phospholipase domain containing 2 0.506
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.472
Ret ret proto-oncogene 0.442
Hspa1b heat shock protein 1B 0.418
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.418
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.394
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.387
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.381
Trp53 transformation related protein 53 0.375
Ar androgen receptor 0.303
Hbb-b1 hemoglobin, beta adult major chain 0.302
Chrd chordin 0.276
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.266
Thra thyroid hormone receptor alpha 0.258
Rpgrip1l Rpgrip1-like 0.248
Thrb thyroid hormone receptor beta 0.247
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.239
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.213
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.189
Drd2 dopamine receptor D2 0.187
Hspa8 heat shock protein 8 0.186
Pparg peroxisome proliferator activated receptor gamma 0.172
Mmp17 matrix metallopeptidase 17 0.156
Rarg retinoic acid receptor, gamma 0.149
Hnrpdl heterogeneous nuclear ribonucleoprotein D-like 0.149
Tlr4 toll-like receptor 4 0.149
Esr1 estrogen receptor 1 (alpha) 0.148
Ghr growth hormone receptor 0.142
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.141
Cav1 caveolin 1, caveolae protein 0.139
Suds3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.134
Hdac1 histone deacetylase 1 0.125
Kl klotho 0.120
Cd44 CD44 antigen 0.120
Bdnf brain derived neurotrophic factor 0.118
Ccl2 chemokine (C-C motif) ligand 2 0.118
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.113
Plcg1 phospholipase C, gamma 1 0.112
Hspa1a heat shock protein 1A 0.112
Gna11 guanine nucleotide binding protein, alpha 11 0.108
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.106
Lep leptin 0.104
Prkce protein kinase C, epsilon 0.103
Rxra retinoid X receptor alpha 0.101
Pax8 paired box gene 8 0.100
Trpc4 transient receptor potential cation channel, subfamily C, member 4 0.098
Prox1 prospero-related homeobox 1 0.098
Pax2 paired box gene 2 0.098
Clock circadian locomotor output cycles kaput 0.095
Col1a1 collagen, type I, alpha 1 0.094
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.093
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.093
Nf1 neurofibromatosis 1 0.092
Il10 interleukin 10 0.091
Insr insulin receptor 0.088
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.084
Cry1 cryptochrome 1 (photolyase-like) 0.083
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.082
Gclm glutamate-cysteine ligase, modifier subunit 0.082
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.081
Vegfa vascular endothelial growth factor A 0.079
Adrb1 adrenergic receptor, beta 1 0.078
Nr2f1 nuclear receptor subfamily 2, group F, member 1 0.078
Apc adenomatosis polyposis coli 0.077
Hsph1 heat shock 105kDa/110kDa protein 1 0.077
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.076
Ppara peroxisome proliferator activated receptor alpha 0.076
Per3 period homolog 3 (Drosophila) 0.075
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.075
Pax6 paired box gene 6 0.074
Mapk14 mitogen-activated protein kinase 14 0.073
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.072
Lhx3 LIM homeobox protein 3 0.069
Lhx6 LIM homeobox protein 6 0.069
Wnt1 wingless-related MMTV integration site 1 0.068
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.068
Cltc clathrin, heavy polypeptide (Hc) 0.066
Lrrk2 leucine-rich repeat kinase 2 0.066
L1cam L1 cell adhesion molecule 0.066
Prkcc protein kinase C, gamma 0.063
E2f1 E2F transcription factor 1 0.063
Emx1 empty spiracles homolog 1 (Drosophila) 0.063
Zfp651 zinc finger protein 651 0.063
Nt5e 5' nucleotidase, ecto 0.062
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.062
Fgfr2 fibroblast growth factor receptor 2 0.062
Nos3 nitric oxide synthase 3, endothelial cell 0.062
Pou4f2 POU domain, class 4, transcription factor 2 0.062
Wt1 Wilms tumor 1 homolog 0.061
Itga3 integrin alpha 3 0.060
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.060
Srsf3 serine/arginine-rich splicing factor 3 0.060
Epha4 Eph receptor A4 0.059
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.656
Il1b interleukin 1 beta 0.603
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.584
Fosl1 fos-like antigen 1 0.544
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.532
Mcpt1 mast cell protease 1 0.516
Cxcl2 chemokine (C-X-C motif) ligand 2 0.479
Hspb1 heat shock protein 1 0.472
Fkbp4 FK506 binding protein 4 0.460
Stip1 stress-induced phosphoprotein 1 0.414
COX3 cytochrome c oxidase subunit 3 0.409
ND3 NADH dehydrogenase subunit 3 0.405
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.375
Socs3 suppressor of cytokine signaling 3 0.366
Cd14 CD14 molecule 0.364
Hspa8 heat shock protein 8 0.339
Foxa3 forkhead box A3 0.331
Kl Klotho 0.326
Icam1 intercellular adhesion molecule 1 0.324
ND1 NADH dehydrogenase subunit 1 0.323
Cxcl10 chemokine (C-X-C motif) ligand 10 0.323
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.318
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.311
CYTB cytochrome b 0.306
Prl prolactin 0.291
Dctn4 dynactin 4 0.288
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.286
Cish cytokine inducible SH2-containing protein 0.284
Reg3a regenerating islet-derived 3 alpha 0.275
Hspa1a heat shock 70kD protein 1A 0.267
Hnrpd heterogeneous nuclear ribonucleoprotein D 0.263
Galr1 galanin receptor 1 0.262
Hsph1 heat shock 105/110 protein 1 0.248
Il1r2 interleukin 1 receptor, type II 0.248
A3galt2 alpha 1,3-galactosyltransferase 2 0.246
Pebp1 phosphatidylethanolamine binding protein 1 0.241
Des desmin 0.232
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.230
Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon 0.227
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 0.226
Nras neuroblastoma ras oncogene 0.222
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.213
Cd44 Cd44 molecule 0.206
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.206
Ubb ubiquitin B 0.200
Ripk3 receptor-interacting serine-threonine kinase 3 0.198
Mmp12 matrix metallopeptidase 12 0.197
ND2 NADH dehydrogenase subunit 2 0.195
Il6 interleukin 6 0.192
P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.189
LOC293989 cytochrome P450-like 0.188
Gpi glucose phosphate isomerase 0.188
Myo1b myosin Ib 0.187
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.187
Ppard peroxisome proliferator-activated receptor delta 0.178
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.177
Tra2b transformer 2 beta homolog (Drosophila) 0.172
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.172
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.170
COX1 cytochrome c oxidase subunit 1 0.170
Crem cAMP responsive element modulator 0.170
Adar adenosine deaminase, RNA-specific 0.168
Casp1 caspase 1 0.167
Ccl2 chemokine (C-C motif) ligand 2 0.161
Ssb Sjogren syndrome antigen B 0.159
Fam38b family with sequence similarity 38, member B 0.158
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.158
Pcna proliferating cell nuclear antigen 0.157
Igfals insulin-like growth factor binding protein, acid labile subunit 0.156
Jak2 Janus kinase 2 0.156
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.155
Atf3 activating transcription factor 3 0.155
Phlda1 pleckstrin homology-like domain, family A, member 1 0.153
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.153
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.151
Ier5 immediate early response 5 0.150
Pyy peptide YY (mapped) 0.147
Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 0.143
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.143
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.141
Foxd3 forkhead box D3 0.141
Cyp51 cytochrome P450, family 51 0.141
Ptgs2 prostaglandin-endoperoxide synthase 2 0.141
Nfasc neurofascin 0.138
Mif macrophage migration inhibitory factor 0.138
Mmp3 matrix metallopeptidase 3 0.137
Mmp13 matrix metallopeptidase 13 0.132
Cct4 chaperonin containing Tcp1, subunit 4 (delta) 0.126
Hck hemopoietic cell kinase 0.125
Nudc nuclear distribution gene C homolog (A. nidulans) 0.125
Olr837 olfactory receptor 837 0.124
Akp3 alkaline phosphatase 3, intestine, not Mn requiring 0.124
Tacr1 tachykinin receptor 1 0.123
Mapk1 mitogen activated protein kinase 1 0.122
Plscr3 phospholipid scramblase 3 0.121
LOC60591 calcium-activated potassium channel beta subunit 0.120
Csf3 colony stimulating factor 3 (granulocyte) 0.120
Agtr1a angiotensin II receptor, type 1a 0.120
Pdk4 pyruvate dehydrogenase kinase, isozyme 4 0.119
Mstn myostatin 0.118