|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.985
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.960
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.939
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.933
|
Human Mouse Rat Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.931
|
Human Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.926
|
Human |
|
|
basement membrane organization
|
GO:0071711 |
3 |
0.914
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.909
|
Rat |
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.907
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.874
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.865
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.854
|
Human Rat |
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.852
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.850
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.835
|
Human Mouse Rat Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.831
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.816
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.811
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.810
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.809
|
Human Mouse Rat Fly |
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.774
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.752
|
Human |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.746
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.744
|
|
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.707
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.700
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.696
|
Human Mouse Rat Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.695
|
Human Rat |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.695
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.682
|
Human Mouse Rat Fly |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.655
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.649
|
Mouse Fly |
|
|
positive regulation of autophagy
|
GO:0010508 |
24 |
0.642
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
7 |
0.638
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.637
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.625
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.612
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.587
|
Human Mouse Rat Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.584
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.561
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.543
|
Human Mouse Rat Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.540
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.512
|
Human Mouse Rat Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.466
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.464
|
Fly |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.448
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.443
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.442
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.438
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.437
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.403
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.380
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.372
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.371
|
Fly |
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.364
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.363
|
Rat |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.363
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.360
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.359
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.358
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.352
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.350
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.340
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.339
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.332
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.328
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.326
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.322
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.314
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.313
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.304
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.304
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
12 |
0.300
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.293
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.291
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.290
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.283
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.281
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.281
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.278
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.277
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.264
|
|
|
|
basement membrane disassembly
|
GO:0034769 |
2 |
0.262
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.259
|
Human Mouse Rat Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.259
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.253
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.251
|
Rat |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.249
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.247
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.244
|
Rat |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.242
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.242
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.231
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.230
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.225
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.225
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.222
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.221
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.216
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.213
|
Fly |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.210
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.204
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.197
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.195
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.194
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.193
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.193
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.191
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.184
|
|
|
|
cellular response to cadmium ion
|
GO:0071276 |
8 |
0.183
|
|
|
|
growth
|
GO:0040007 |
202 |
0.182
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.180
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.179
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.177
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.175
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.174
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.173
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.173
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.165
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.165
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.163
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.161
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.159
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.159
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.158
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.156
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.156
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.153
|
|
|
|
acylglycerol homeostasis
|
GO:0055090 |
14 |
0.148
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.146
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.146
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.145
|
Rat |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.144
|
|
|
|
mating
|
GO:0007618 |
1 |
0.140
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.140
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.139
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.139
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.138
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.136
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.135
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.134
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.132
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.132
|
Human Mouse Rat Fly |
|
|
axon regeneration
|
GO:0031103 |
1 |
0.131
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.129
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.129
|
Rat |
|
|
system process
|
GO:0003008 |
349 |
0.128
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.123
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.121
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.120
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.120
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.120
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.119
|
Mouse Rat |
|
|
visual learning
|
GO:0008542 |
1 |
0.118
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.117
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.115
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.115
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.114
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.114
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.112
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.111
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.110
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.110
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.109
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.109
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.108
|
Rat |
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.108
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.106
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.103
|
Fly |
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.102
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.101
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.101
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.098
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.097
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.097
|
Mouse Rat |
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.097
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.096
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.095
|
|
|
|
extracellular matrix disassembly
|
GO:0022617 |
16 |
0.093
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.092
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.092
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.091
|
|
|
|
pigment metabolic process
|
GO:0042440 |
16 |
0.090
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.089
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.088
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.088
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.086
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.086
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.084
|
|
|
|
memory
|
GO:0007613 |
3 |
0.084
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.083
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.083
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.083
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.082
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.080
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.079
|
|
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
16 |
0.078
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.078
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.077
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.077
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.077
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.076
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.076
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.075
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.074
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.073
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.073
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.073
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.072
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.072
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.072
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.072
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.071
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.071
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.071
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.071
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.067
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.067
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.065
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.065
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.064
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.064
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.063
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.063
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.063
|
Rat |
|
|
axon extension
|
GO:0048675 |
13 |
0.063
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.063
|
Rat |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.062
|
|
|
|
response to cadmium ion
|
GO:0046686 |
10 |
0.062
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.062
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.062
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.061
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.061
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.060
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.059
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.059
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.059
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.058
|
Mouse Rat |
|
|
neurological system process
|
GO:0050877 |
163 |
0.057
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.057
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
11 |
0.057
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.057
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.056
|
|
|
|
triglyceride homeostasis
|
GO:0070328 |
14 |
0.056
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.056
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.056
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.056
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.056
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.055
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.055
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.055
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.053
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.052
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.051
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.051
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.051
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.050
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.050
|
Rat |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.049
|
Fly |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.048
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.048
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.048
|
Rat |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.048
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.048
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.048
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.047
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.047
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.046
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.046
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.046
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.046
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.045
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.045
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.045
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.045
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.045
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.044
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.044
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.044
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.044
|
Rat |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.044
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.044
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.043
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.043
|
Rat |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.043
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.042
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.042
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.042
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.042
|
|
|
|
somite development
|
GO:0061053 |
7 |
0.041
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.041
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.041
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.041
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.041
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.041
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.040
|
Rat |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.040
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.040
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.040
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.040
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.040
|
Rat |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.039
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.039
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.039
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.038
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.038
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.038
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.038
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.036
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.036
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.036
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.036
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.036
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.036
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.035
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.035
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.034
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.034
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.034
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.034
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.034
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.034
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.034
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.033
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.033
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.033
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.033
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.033
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.032
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.032
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.032
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.031
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.031
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.031
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.031
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.031
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.030
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.030
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.030
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.030
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.030
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.030
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.030
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.030
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.030
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.030
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.030
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.030
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.029
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.029
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.029
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.029
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.029
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.029
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.029
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.029
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.029
|
Fly |
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.029
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.028
|
Mouse Rat |
|
|
dna conformation change
|
GO:0071103 |
113 |
0.028
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.028
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.028
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.028
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.028
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.028
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.028
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.028
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.028
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.027
|
|
|
|
aging
|
GO:0007568 |
66 |
0.027
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.027
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.026
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.026
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.026
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.026
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.026
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.026
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.026
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.026
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.026
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.025
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.025
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.025
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.025
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.025
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.025
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.025
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.025
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.025
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.025
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.025
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.025
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.025
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.025
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.025
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.024
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.024
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.023
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.023
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.023
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.023
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.023
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.023
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.023
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.023
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.023
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.023
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.023
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.022
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.022
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.022
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.022
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.022
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.022
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.022
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.022
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.022
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.022
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.022
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.022
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.022
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.022
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.022
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.021
|
Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.021
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.021
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.021
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
6 |
0.021
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.021
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.021
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.021
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.021
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.021
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.021
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.021
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.021
|
|
|
|
microtubule based transport
|
GO:0010970 |
21 |
0.021
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.021
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.021
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.020
|
Mouse Rat |
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.020
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.020
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.020
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.020
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.020
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.020
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.020
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.020
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.020
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.019
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.019
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.019
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.019
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.019
|
Rat |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.019
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.019
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.019
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.019
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.019
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.019
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.019
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.019
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.019
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.019
|
Mouse |
|
|
cellular response to reactive nitrogen species
|
GO:1902170 |
2 |
0.019
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.018
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.018
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.018
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.018
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.018
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.018
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.018
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.018
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.018
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.018
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.018
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.018
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.018
|
Rat |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.018
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.018
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.017
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.017
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.017
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.017
|
|
