Homo sapiens

24 known processes

IL1R1

interleukin 1 receptor, type I

(Aliases: CD121A,IL1R,P80,IL1RA,D2S1473,IL-1R-alpha)

IL1R1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of interferon gamma secretion GO:1902714 1 1.000
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 1.000
negative regulation of amine transport GO:0051953 1 1.000
positive regulation of myosin light chain kinase activity GO:0035505 1 1.000
positive regulation of calcidiol 1 monooxygenase activity GO:0060559 3 1.000
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 1.000
positive regulation of alcohol biosynthetic process GO:1902932 9 1.000
monocyte aggregation GO:0070487 4 0.999
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 4 0.999
positive regulation of vitamin metabolic process GO:0046136 3 0.999
regulation of chemokine production GO:0032642 31 0.997
cell cell adhesion involved in gastrulation GO:0070586 6 0.996
activation of mapk activity GO:0000187 45 0.995
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.994
amino acid transport GO:0006865 28 0.994
negative regulation of lipid catabolic process GO:0050995 9 0.993
activation of protein kinase activity GO:0032147 90 0.993
regulation of amine transport GO:0051952 5 0.992
negative regulation of interleukin 1 mediated signaling pathway GO:2000660 2 0.992
regulation of lipid catabolic process GO:0050994 23 0.990
anion transport GO:0006820 161 0.988
fat soluble vitamin metabolic process GO:0006775 19 0.987
chemokine production GO:0032602 32 0.983
sequestering of triglyceride GO:0030730 11 0.982
positive regulation of steroid biosynthetic process GO:0010893 6 0.975
cytokine production GO:0001816 247 0.972
response to interleukin 1 GO:0070555 47 0.968
aminoglycan metabolic process GO:0006022 39 0.967
positive regulation of lipid biosynthetic process GO:0046889 22 0.966
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.965
Human
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.963
negative regulation of interleukin 17 production GO:0032700 5 0.962
positive regulation of acute inflammatory response GO:0002675 2 0.959
positive regulation of stress activated mapk cascade GO:0032874 60 0.957
reactive nitrogen species metabolic process GO:2001057 3 0.955
regulation of chemokine biosynthetic process GO:0045073 4 0.953
negative regulation of lipid metabolic process GO:0045833 38 0.949
cytokine mediated signaling pathway GO:0019221 109 0.948
positive regulation of jun kinase activity GO:0043507 23 0.947
response to cytokine GO:0034097 232 0.944
positive regulation of steroid metabolic process GO:0045940 13 0.943
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.939
negative regulation of cytokine production GO:0001818 82 0.939
reactive oxygen species biosynthetic process GO:1903409 4 0.937
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.937
positive regulation of kinase activity GO:0033674 204 0.936
positive regulation of protein phosphorylation GO:0001934 313 0.935
cellular response to cytokine stimulus GO:0071345 181 0.932
interleukin 2 production GO:0032623 20 0.932
nitric oxide biosynthetic process GO:0006809 20 0.929
organic anion transport GO:0015711 103 0.928
vitamin d metabolic process GO:0042359 10 0.928
chemokine metabolic process GO:0050755 4 0.926
negative regulation of multicellular organismal process GO:0051241 317 0.923
negative regulation of cell adhesion GO:0007162 64 0.922
regulation of cytokine mediated signaling pathway GO:0001959 41 0.922
acute phase response GO:0006953 5 0.920
positive regulation of interferon gamma production GO:0032729 26 0.918
membrane protein ectodomain proteolysis GO:0006509 33 0.914
lipid biosynthetic process GO:0008610 177 0.911
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.910
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.909
positive regulation of nf kappab import into nucleus GO:0042346 13 0.908
positive regulation of vitamin d biosynthetic process GO:0060557 3 0.908
reactive oxygen species metabolic process GO:0072593 75 0.906
positive regulation of lymphocyte proliferation GO:0050671 46 0.905
heterotypic cell cell adhesion GO:0034113 28 0.904
positive regulation of phosphorylation GO:0042327 394 0.904
regulation of myosin light chain kinase activity GO:0035504 1 0.903
regulation of cytokine production GO:0001817 232 0.900
vitamin metabolic process GO:0006766 26 0.899
lipid catabolic process GO:0016042 84 0.897
positive regulation of nitric oxide biosynthetic process GO:0045429 13 0.893
positive regulation of transcription factor import into nucleus GO:0042993 25 0.890
positive regulation of heterotypic cell cell adhesion GO:0034116 8 0.889
steroid biosynthetic process GO:0006694 46 0.887
cytokine biosynthetic process GO:0042089 37 0.887
regulation of jun kinase activity GO:0043506 27 0.883
regulation of jnk cascade GO:0046328 73 0.883
regulation of stress activated mapk cascade GO:0032872 84 0.882
regulation of map kinase activity GO:0043405 108 0.876
positive regulation of gliogenesis GO:0014015 4 0.871
chemokine biosynthetic process GO:0042033 4 0.869
positive regulation of chemokine production GO:0032722 22 0.868
positive regulation of protein import into nucleus GO:0042307 46 0.865
regulation of gastrulation GO:0010470 12 0.864
regulation of interleukin 17 production GO:0032660 12 0.859
granulocyte macrophage colony stimulating factor production GO:0032604 5 0.856
interleukin 6 production GO:0032635 37 0.853
multicellular organismal homeostasis GO:0048871 67 0.851
i kappab kinase nf kappab signaling GO:0007249 166 0.850
response to activity GO:0014823 0 0.847
positive regulation of cytokine production GO:0001819 167 0.846
regulation of anion transport GO:0044070 25 0.843
positive regulation of organic acid transport GO:0032892 3 0.839
interleukin 17 production GO:0032620 12 0.838
positive regulation of protein kinase activity GO:0045860 190 0.835
organic acid transport GO:0015849 65 0.830
positive regulation of transferase activity GO:0051347 227 0.830
positive regulation of mapk cascade GO:0043410 190 0.829
interleukin 1 mediated signaling pathway GO:0070498 12 0.819
regulation of reactive oxygen species metabolic process GO:2000377 41 0.815
regulation of steroid metabolic process GO:0019218 32 0.815
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 5 0.814
acid secretion GO:0046717 12 0.814
hormone metabolic process GO:0042445 61 0.805
lymphocyte activation GO:0046649 133 0.804
regulation of mitosis GO:0007088 63 0.801
positive regulation of fatty acid transport GO:2000193 3 0.800
carboxylic acid transport GO:0046942 63 0.797
lipid metabolic process GO:0006629 381 0.792
cellular lipid metabolic process GO:0044255 303 0.791
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.791
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.790
cellular response to interleukin 1 GO:0071347 35 0.785
glycosaminoglycan biosynthetic process GO:0006024 27 0.784
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.779
mucopolysaccharide metabolic process GO:1903510 27 0.776
leukocyte aggregation GO:0070486 8 0.776
steroid metabolic process GO:0008202 94 0.775
negative regulation of heterotypic cell cell adhesion GO:0034115 6 0.775
regulation of nitric oxide biosynthetic process GO:0045428 17 0.775
negative regulation of cell cell adhesion GO:0022408 27 0.772
isoprenoid metabolic process GO:0006720 39 0.770
membrane protein proteolysis GO:0033619 38 0.769
organonitrogen compound biosynthetic process GO:1901566 200 0.768
positive regulation of icosanoid secretion GO:0032305 3 0.766
memory GO:0007613 3 0.764
positive regulation of t cell proliferation GO:0042102 33 0.759
peptide secretion GO:0002790 51 0.759
cellular response to mechanical stimulus GO:0071260 39 0.758
cellular response to abiotic stimulus GO:0071214 117 0.752
regulation of lymphocyte activation GO:0051249 103 0.751
leukocyte proliferation GO:0070661 74 0.751
positive regulation of leukocyte activation GO:0002696 80 0.748
positive regulation of immune system process GO:0002684 283 0.742
inflammatory response to antigenic stimulus GO:0002437 4 0.742
response to oxygen containing compound GO:1901700 369 0.739
Rat
negative regulation of response to cytokine stimulus GO:0060761 25 0.739
positive regulation of jnk cascade GO:0046330 52 0.736
regulation of protein secretion GO:0050708 86 0.736
regulation of transferase activity GO:0051338 355 0.734
positive regulation of cell division GO:0051781 59 0.734
positive regulation of mononuclear cell proliferation GO:0032946 47 0.733
small molecule biosynthetic process GO:0044283 157 0.731
tube morphogenesis GO:0035239 95 0.729
digestive tract morphogenesis GO:0048546 56 0.725
regulation of hormone levels GO:0010817 125 0.724
organic hydroxy compound metabolic process GO:1901615 147 0.717
regulation of cell migration GO:0030334 289 0.716
response to oxidative stress GO:0006979 121 0.715
Rat
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.715
cellular response to oxygen containing compound GO:1901701 276 0.713
Rat
defense response GO:0006952 315 0.710
Mouse
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.710
organic hydroxy compound biosynthetic process GO:1901617 71 0.707
cellular response to biotic stimulus GO:0071216 71 0.707
positive regulation of protein catabolic process GO:0045732 75 0.702
positive regulation of interleukin 6 production GO:0032755 21 0.701
positive regulation vascular endothelial growth factor production GO:0010575 12 0.697
regulation of vitamin metabolic process GO:0030656 9 0.693
cellular hormone metabolic process GO:0034754 41 0.691
response to organonitrogen compound GO:0010243 156 0.688
positive regulation of mitosis GO:0045840 25 0.683
regulation of protein localization to nucleus GO:1900180 85 0.682
cellular response to external stimulus GO:0071496 111 0.681
positive regulation of angiogenesis GO:0045766 51 0.681
alcohol metabolic process GO:0006066 114 0.680
hormone secretion GO:0046879 65 0.671
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.667
cellular response to molecule of bacterial origin GO:0071219 62 0.667
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.665
cellular response to lipid GO:0071396 127 0.655
regulation of neural precursor cell proliferation GO:2000177 4 0.653
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.653
cellular response to endogenous stimulus GO:0071495 336 0.652
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.649
regulation of locomotion GO:0040012 329 0.648
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.647
regulation of vitamin d biosynthetic process GO:0060556 8 0.646
acute inflammatory response GO:0002526 21 0.643
signal transduction by phosphorylation GO:0023014 297 0.642
developmental programmed cell death GO:0010623 3 0.640
positive regulation of t cell activation GO:0050870 54 0.635
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.627
cellular response to organic cyclic compound GO:0071407 127 0.623
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.621
leukocyte activation GO:0045321 164 0.613
vascular endothelial growth factor production GO:0010573 15 0.611
positive regulation of map kinase activity GO:0043406 80 0.607
positive regulation of interleukin 8 production GO:0032757 36 0.607
regulation of kinase activity GO:0043549 314 0.606
regulation of lymphocyte proliferation GO:0050670 64 0.605
regulation of mononuclear cell proliferation GO:0032944 65 0.602
morphogenesis of a branching structure GO:0001763 21 0.602
regulation of protein serine threonine kinase activity GO:0071900 179 0.597
regulation of lipid metabolic process GO:0019216 96 0.592
regulation of protein catabolic process GO:0042176 155 0.590
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.589
protein targeting GO:0006605 187 0.586
regulation of alcohol biosynthetic process GO:1902930 22 0.585
regulation of t cell activation GO:0050863 77 0.585
regulation of lipid biosynthetic process GO:0046890 47 0.582
response to molecule of bacterial origin GO:0002237 82 0.580
interferon gamma production GO:0032609 39 0.580
regulation of monocyte chemotactic protein 1 production GO:0071637 6 0.577
mitotic cell cycle process GO:1903047 286 0.576
negative regulation of cellular component movement GO:0051271 106 0.572
t cell activation GO:0042110 99 0.571
endocrine process GO:0050886 25 0.571
positive regulation of chemokine biosynthetic process GO:0045080 3 0.567
endocrine hormone secretion GO:0060986 13 0.567
t cell differentiation in thymus GO:0033077 4 0.562
regulation of steroid biosynthetic process GO:0050810 23 0.559
regulation of response to cytokine stimulus GO:0060759 46 0.558
regulation of t cell proliferation GO:0042129 42 0.557
positive regulation of cell activation GO:0050867 81 0.557
protein targeting to nucleus GO:0044744 104 0.556
positive regulation of protein transport GO:0051222 135 0.554
positive regulation of proteolysis GO:0045862 142 0.554
nucleocytoplasmic transport GO:0006913 176 0.546
glycosaminoglycan metabolic process GO:0030203 35 0.542
hyaluronan metabolic process GO:0030212 15 0.541
positive regulation of intracellular transport GO:0032388 104 0.530
nitric oxide metabolic process GO:0046209 22 0.528
blood vessel morphogenesis GO:0048514 162 0.526
regulation of cytokine biosynthetic process GO:0042035 35 0.525
embryonic morphogenesis GO:0048598 85 0.523
prostaglandin transport GO:0015732 2 0.522
positive regulation of oxidoreductase activity GO:0051353 26 0.521
regulation of protein kinase activity GO:0045859 289 0.520
glucose homeostasis GO:0042593 31 0.519
Rat
regulation of heterotypic cell cell adhesion GO:0034114 14 0.518
regulation of protein targeting GO:1903533 91 0.516
positive regulation of cytokine biosynthetic process GO:0042108 25 0.515
negative regulation of locomotion GO:0040013 118 0.514
regulation of astrocyte differentiation GO:0048710 3 0.513
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.513
regulation of mapk cascade GO:0043408 262 0.510
cellular response to monoamine stimulus GO:0071868 7 0.508
nf kappab import into nucleus GO:0042348 22 0.505
cellular response to nitrogen compound GO:1901699 144 0.505
regulation of icosanoid secretion GO:0032303 4 0.505
interleukin 8 production GO:0032637 51 0.502
regulation of vascular endothelial growth factor production GO:0010574 13 0.501
regulation of cell motility GO:2000145 299 0.500
regulation of oxidoreductase activity GO:0051341 43 0.499
negative regulation of catabolic process GO:0009895 104 0.498
positive regulation of intracellular protein transport GO:0090316 76 0.497
positive regulation of cell cell adhesion GO:0022409 22 0.491
jnk cascade GO:0007254 80 0.490
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.489
peptide transport GO:0015833 74 0.484
terpenoid metabolic process GO:0006721 27 0.483
estrogen metabolic process GO:0008210 6 0.482
regulation of leukocyte activation GO:0002694 115 0.482
immune response GO:0006955 307 0.479
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.479
interleukin 2 biosynthetic process GO:0042094 7 0.478
response to extracellular stimulus GO:0009991 85 0.475
icosanoid transport GO:0071715 11 0.474
positive regulation of catabolic process GO:0009896 310 0.473
regulation of protein transport GO:0051223 213 0.473
positive regulation of leukocyte proliferation GO:0070665 48 0.472
regulation of secretion by cell GO:1903530 177 0.469
protein secretion GO:0009306 98 0.466
negative regulation of protein metabolic process GO:0051248 391 0.463
fatty acid derivative transport GO:1901571 11 0.458
positive regulation of developmental process GO:0051094 314 0.456
female gamete generation GO:0007292 2 0.448
Rat
lipid localization GO:0010876 106 0.446
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.444
astrocyte differentiation GO:0048708 4 0.442
regulation of nuclear division GO:0051783 65 0.440
nucleobase metabolic process GO:0009112 8 0.440
regulation of proteolysis GO:0030162 293 0.439
regulation of peptide hormone secretion GO:0090276 41 0.437
positive regulation of lipid metabolic process GO:0045834 50 0.437
anatomical structure formation involved in morphogenesis GO:0048646 284 0.435
stress activated mapk cascade GO:0051403 93 0.432
regulation of cellular amino acid metabolic process GO:0006521 6 0.432
regulation of insulin secretion GO:0050796 33 0.432
response to lipid GO:0033993 206 0.430
transcription factor import into nucleus GO:0042991 40 0.427
mapk cascade GO:0000165 288 0.426
vasculature development GO:0001944 181 0.425
positive regulation of lymphocyte activation GO:0051251 73 0.424
regulation of glial cell differentiation GO:0045685 3 0.421
monocyte chemotactic protein 1 production GO:0071605 6 0.419
gastrulation GO:0007369 51 0.418
cell division GO:0051301 168 0.416
mitotic cell cycle GO:0000278 326 0.416
regulation of intracellular transport GO:0032386 195 0.408
positive regulation of cellular catabolic process GO:0031331 284 0.406
lipid transport GO:0006869 90 0.404
nuclear transport GO:0051169 179 0.404
regulation of cell cycle process GO:0010564 266 0.401
positive regulation of nuclear division GO:0051785 27 0.398
alcohol biosynthetic process GO:0046165 52 0.397
negative regulation of transport GO:0051051 176 0.396
regulation of mitotic cell cycle GO:0007346 189 0.396
interleukin 1 production GO:0032612 26 0.393
cytokine metabolic process GO:0042107 38 0.391
regulation of cellular response to stress GO:0080135 244 0.388
regulation of cell cell adhesion GO:0022407 57 0.381
peptide hormone secretion GO:0030072 50 0.381
negative regulation of ion transport GO:0043271 39 0.380
regulation of ion transport GO:0043269 189 0.379
hormone transport GO:0009914 68 0.378
positive regulation of organelle organization GO:0010638 195 0.377
response to glucocorticoid GO:0051384 13 0.376
leukocyte cell cell adhesion GO:0007159 37 0.376
response to nutrient levels GO:0031667 81 0.375
carbohydrate derivative biosynthetic process GO:1901137 207 0.372
regulation of intracellular protein transport GO:0033157 123 0.371
protein localization to nucleus GO:0034504 136 0.371
circulatory system development GO:0072359 262 0.363
regulation of nucleocytoplasmic transport GO:0046822 98 0.363
cellular response to organonitrogen compound GO:0071417 124 0.350
regulation of apoptotic signaling pathway GO:2001233 175 0.346
response to drug GO:0042493 81 0.343
response to steroid hormone GO:0048545 80 0.341
hexose transport GO:0008645 30 0.341
apoptotic signaling pathway GO:0097190 268 0.337
angiogenesis GO:0001525 147 0.337
regulation of hormone secretion GO:0046883 57 0.336
enzyme linked receptor protein signaling pathway GO:0007167 303 0.335
protein kinase b signaling GO:0043491 69 0.333
positive regulation of interleukin 6 biosynthetic process GO:0045410 1 0.332
regulation of monooxygenase activity GO:0032768 22 0.332
vitamin biosynthetic process GO:0009110 11 0.332
positive regulation of protein localization to nucleus GO:1900182 48 0.329
regulation of cytoplasmic transport GO:1903649 149 0.329
regulation of establishment of protein localization GO:0070201 242 0.327
positive regulation of interleukin 2 production GO:0032743 11 0.327
single organism cellular localization GO:1902580 332 0.319
regulation of protein localization GO:0032880 296 0.317
regulation of anatomical structure morphogenesis GO:0022603 286 0.315
insulin secretion GO:0030073 39 0.315
organelle fission GO:0048285 149 0.313
response to phenylpropanoid GO:0080184 1 0.313
polyketide metabolic process GO:0030638 8 0.312
positive regulation of transport GO:0051050 336 0.311
regulation of cell development GO:0060284 161 0.310
regulation of prostaglandin secretion GO:0032306 2 0.309
response to organic cyclic compound GO:0014070 204 0.308
positive regulation of cell adhesion GO:0045785 84 0.308
regulation of interferon gamma production GO:0032649 36 0.308
system process GO:0003008 349 0.307
regulation of calcidiol 1 monooxygenase activity GO:0060558 6 0.307
cytokine secretion GO:0050663 64 0.306
response to monosaccharide GO:0034284 20 0.305
Rat
positive regulation of defense response GO:0031349 87 0.305
cellular amine metabolic process GO:0044106 41 0.301
regulation of cell differentiation GO:0045595 393 0.301
negative regulation of cell proliferation GO:0008285 228 0.300
digestive system development GO:0055123 75 0.300
tube development GO:0035295 125 0.300
regulation of cell activation GO:0050865 125 0.298
negative regulation of apoptotic signaling pathway GO:2001234 97 0.295
regulation of cell adhesion GO:0030155 166 0.291
positive regulation of prostaglandin secretion GO:0032308 1 0.290
regulation of endocrine process GO:0044060 12 0.288
protein import GO:0017038 130 0.283
positive regulation of cell cycle GO:0045787 140 0.280
cellular response to toxic substance GO:0097237 4 0.279
digestive tract development GO:0048565 75 0.277
t cell proliferation GO:0042098 45 0.274
response to transition metal nanoparticle GO:1990267 29 0.273
signal transduction in absence of ligand GO:0038034 22 0.273
regulation of organic acid transport GO:0032890 8 0.272
negative regulation of cell death GO:0060548 345 0.271
regulation of leukocyte proliferation GO:0070663 67 0.270
regulation of nf kappab import into nucleus GO:0042345 22 0.268
positive regulation of cell development GO:0010720 92 0.268
response to other organism GO:0051707 261 0.267
regulation of cell cell adhesion involved in gastrulation GO:0070587 6 0.265
positive regulation of lipid catabolic process GO:0050996 13 0.264
secretion by cell GO:0032940 226 0.264
negative regulation of neural precursor cell proliferation GO:2000178 1 0.264
negative regulation of cellular protein metabolic process GO:0032269 353 0.263
response to hormone GO:0009725 175 0.261
positive regulation of secretion by cell GO:1903532 108 0.260
protein import into nucleus GO:0006606 104 0.258
negative regulation of secretion by cell GO:1903531 52 0.258
protein catabolic process GO:0030163 325 0.255
response to dsrna GO:0043331 25 0.255
amide transport GO:0042886 76 0.252
cell activation GO:0001775 213 0.252
positive regulation of toll like receptor signaling pathway GO:0034123 10 0.251
fat soluble vitamin biosynthetic process GO:0042362 11 0.251
response to organophosphorus GO:0046683 41 0.250
regulation of secretion GO:0051046 194 0.248
regulation of lipid transport GO:0032368 44 0.248
response to fungus GO:0009620 4 0.243
negative regulation of catalytic activity GO:0043086 335 0.240
negative regulation of secretion GO:0051048 58 0.240
lymphocyte proliferation GO:0046651 70 0.237
negative regulation of developmental process GO:0051093 247 0.236
cellular response to lipopolysaccharide GO:0071222 57 0.235
vitamin d biosynthetic process GO:0042368 9 0.235
antifungal humoral response GO:0019732 2 0.231
regulation of cytokine secretion GO:0050707 57 0.230
positive regulation of mitotic cell cycle GO:0045931 60 0.230
carbohydrate homeostasis GO:0033500 31 0.229
Rat
regulation of interleukin 2 biosynthetic process GO:0045076 7 0.228
intracellular protein transport GO:0006886 270 0.228
monocarboxylic acid transport GO:0015718 32 0.224
regulation of peptide secretion GO:0002791 42 0.224
single organismal cell cell adhesion GO:0016337 148 0.219
regulation of cell division GO:0051302 116 0.215
response to vitamin d GO:0033280 10 0.215
response to external biotic stimulus GO:0043207 261 0.214
fatty acid metabolic process GO:0006631 115 0.208
mitotic nuclear division GO:0007067 119 0.208
response to bacterium GO:0009617 144 0.208
mononuclear cell proliferation GO:0032943 71 0.206
blood vessel development GO:0001568 172 0.206
glycoprotein metabolic process GO:0009100 110 0.205
positive regulation of cellular component organization GO:0051130 376 0.204
response to lipopolysaccharide GO:0032496 70 0.204
regulation of cell cycle GO:0051726 393 0.202
stress activated protein kinase signaling cascade GO:0031098 94 0.201
defense response to fungus GO:0050832 4 0.200
response to abiotic stimulus GO:0009628 336 0.200
Rat
humoral immune response GO:0006959 49 0.200
establishment of protein localization to organelle GO:0072594 172 0.197
response to corticosteroid GO:0031960 15 0.197
negative regulation of cell differentiation GO:0045596 171 0.197
cellular response to drug GO:0035690 27 0.196
regulation of cellular amine metabolic process GO:0033238 11 0.196
negative regulation of map kinase activity GO:0043407 27 0.194
negative regulation of cell migration GO:0030336 102 0.193
neurological system process GO:0050877 163 0.192
response to biotic stimulus GO:0009607 276 0.191
amine transport GO:0015837 7 0.191
reproductive process GO:0022414 106 0.190
Rat
cellular response to hormone stimulus GO:0032870 125 0.190
regulation of protein import into nucleus GO:0042306 78 0.190
activation of immune response GO:0002253 114 0.189
nik nf kappab signaling GO:0038061 12 0.188
response to nitrogen compound GO:1901698 184 0.186
Rat
cellular glucose homeostasis GO:0001678 11 0.184
Rat
regulation of response to wounding GO:1903034 101 0.183
Mouse
positive regulation of apoptotic process GO:0043065 246 0.182
signal release GO:0023061 70 0.181
nuclear division GO:0000280 128 0.180
negative regulation of apoptotic process GO:0043066 316 0.180
positive regulation of locomotion GO:0040017 186 0.180
cytoplasmic transport GO:0016482 379 0.179
negative regulation of organic acid transport GO:0032891 6 0.178
negative regulation of phosphate metabolic process GO:0045936 267 0.176
regulation of cellular component movement GO:0051270 334 0.175
monocarboxylic acid metabolic process GO:0032787 185 0.174
defense response to other organism GO:0098542 129 0.174
regulation of cellular ketone metabolic process GO:0010565 50 0.174
cellular response to antibiotic GO:0071236 1 0.173
regulation of innate immune response GO:0045088 97 0.172
regulation of membrane protein ectodomain proteolysis GO:0051043 17 0.171
negative regulation of programmed cell death GO:0043069 321 0.169
secretion GO:0046903 254 0.168
nitrogen compound transport GO:0071705 191 0.167
response to oxygen levels GO:0070482 100 0.163
response to copper ion GO:0046688 8 0.162
aminoglycan biosynthetic process GO:0006023 29 0.160
extrinsic apoptotic signaling pathway GO:0097191 119 0.159
regulation of insulin receptor signaling pathway GO:0046626 13 0.159
response to nutrient GO:0007584 20 0.158
regulation of defense response GO:0031347 154 0.158
Mouse
ion homeostasis GO:0050801 230 0.158
regulation of embryonic development GO:0045995 20 0.157
response to peptide GO:1901652 65 0.157
cellular response to heat GO:0034605 14 0.157
response to reactive oxygen species GO:0000302 61 0.156
Rat
positive regulation of protein secretion GO:0050714 60 0.155
positive regulation of cytokine secretion GO:0050715 42 0.152
positive regulation of neutrophil chemotaxis GO:0090023 7 0.150
negative regulation of protein modification process GO:0031400 200 0.148
regulation of acute inflammatory response GO:0002673 13 0.148
negative regulation of cell development GO:0010721 48 0.145
cellular response to catecholamine stimulus GO:0071870 7 0.143
regulation of peptide transport GO:0090087 62 0.140
nuclear import GO:0051170 106 0.139
chemical homeostasis GO:0048878 306 0.139
Rat
negative regulation of protein phosphorylation GO:0001933 140 0.138
negative regulation of phosphorus metabolic process GO:0010563 267 0.138
positive regulation of cell migration GO:0030335 172 0.137
response to estrogen GO:0043627 47 0.136
negative regulation of cell motility GO:2000146 104 0.134
positive regulation of cell differentiation GO:0045597 211 0.133
regulation of vasculature development GO:1901342 97 0.131
erk1 and erk2 cascade GO:0070371 104 0.130
response to ionizing radiation GO:0010212 65 0.129
negative regulation of hormone secretion GO:0046888 15 0.129

IL1R1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.931
cancer DOID:162 167 0.874
organ system cancer DOID:0050686 164 0.874
gastrointestinal system cancer DOID:3119 52 0.731
stomach cancer DOID:10534 12 0.449