IMP

Process View

Homo sapiens

15 genes annotated in human

vascular endothelial growth factor production

The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "vascular endothelial growth factor production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "vascular endothelial growth factor production" (in gray)

Name	Description	Probability	Func Analog Organism
VEGFA	vascular endothelial growth factor A	0.762
EPAS1	endothelial PAS domain protein 1	0.617	Human
IL1R1	interleukin 1 receptor, type I	0.611
AHR	aryl hydrocarbon receptor	0.536
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.472
IL1B	interleukin 1, beta	0.410
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.372	Human
NRP1	neuropilin 1	0.325
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.298	Human
EGLN1	egl nine homolog 1 (C. elegans)	0.167
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.166
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.115
EGLN3	egl nine homolog 3 (C. elegans)	0.094
IL6R	interleukin 6 receptor	0.080
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.076	Human
PGF	placental growth factor	0.076
CLOCK	clock homolog (mouse)	0.073
IL1RN	interleukin 1 receptor antagonist	0.069	Human
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.066	Human
BMPR1B	bone morphogenetic protein receptor, type IB	0.065
VHL	von Hippel-Lindau tumor suppressor	0.065
CDH5	cadherin 5, type 2 (vascular endothelium)	0.065
IL1RAP	interleukin 1 receptor accessory protein	0.058
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.049
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.046
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.042
SSX4	synovial sarcoma, X breakpoint 4	0.039
KITLG	KIT ligand	0.036
CD86	CD86 molecule	0.034
APOE	apolipoprotein E	0.034
CLEC7A	C-type lectin domain family 7, member A	0.034
PLAUR	plasminogen activator, urokinase receptor	0.032
VSIG4	V-set and immunoglobulin domain containing 4	0.032
IL8	interleukin 8	0.028
IL1R2	interleukin 1 receptor, type II	0.027
ARNT	aryl hydrocarbon receptor nuclear translocator	0.025
CFH	complement factor H	0.025
PDGFA	platelet-derived growth factor alpha polypeptide	0.024
CCR1	chemokine (C-C motif) receptor 1	0.022
STAB1	stabilin 1	0.022
CLEC4A	C-type lectin domain family 4, member A	0.021
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.021
GAB1	GRB2-associated binding protein 1	0.020
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.019
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.019
LAT	linker for activation of T cells	0.018
FGFR1	fibroblast growth factor receptor 1	0.017
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.017	Rat
SP1	Sp1 transcription factor	0.017
TBX5	T-box 5	0.017
BCL2A1	BCL2-related protein A1	0.017
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.016
VCAN	versican	0.016
CSF1R	colony stimulating factor 1 receptor	0.016	Human
TLR2	toll-like receptor 2	0.016
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.016
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.015
CYBB	cytochrome b-245, beta polypeptide	0.014	Human
LDLR	low density lipoprotein receptor	0.014
FPR1	formyl peptide receptor 1	0.014
FGL2	fibrinogen-like 2	0.014
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.014
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
NOG	noggin	0.014
SLA	Src-like-adaptor	0.014
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.013
CLEC5A	C-type lectin domain family 5, member A	0.013
MSR1	macrophage scavenger receptor 1	0.013
CCL2	chemokine (C-C motif) ligand 2	0.013
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.013
NCOA2	nuclear receptor coactivator 2	0.013
VEGFC	vascular endothelial growth factor C	0.013
NCF2	neutrophil cytosolic factor 2	0.012
STC1	stanniocalcin 1	0.012
PDGFC	platelet derived growth factor C	0.012
AQP9	aquaporin 9	0.012
CCR2	chemokine (C-C motif) receptor 2	0.012	Mouse
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.012
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.011
CD163	CD163 molecule	0.011
PTPRB	protein tyrosine phosphatase, receptor type, B	0.011
WISP1	WNT1 inducible signaling pathway protein 1	0.011
PLEK	pleckstrin	0.011
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
GREM1	gremlin 1	0.011
CD93	CD93 molecule	0.011
HMGCL	3-hydroxymethyl-3-methylglutaryl-CoA lyase	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.010