Homo sapiens

186 known processes

TRIM5

tripartite motif containing 5

(Aliases: RNF88,TRIM5alpha)

TRIM5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 0.956
negative regulation of viral release from host cell GO:1902187 12 0.805
regulation of interleukin 2 secretion GO:1900040 2 0.804
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.798
positive regulation of viral entry into host cell GO:0046598 3 0.716
Human Mouse
positive regulation of rig i signaling pathway GO:1900246 4 0.590
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.573
protein modification by small protein conjugation GO:0032446 342 0.555
protein autoubiquitination GO:0051865 37 0.541
Human Mouse
regulation of viral transcription GO:0046782 34 0.526
Human
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.466
Human
modification dependent protein catabolic process GO:0019941 209 0.416
Human
multi organism cellular process GO:0044764 156 0.400
interleukin 2 secretion GO:0070970 3 0.400
Human
negative regulation of protein deubiquitination GO:0090086 3 0.386
Human
modification dependent macromolecule catabolic process GO:0043632 212 0.379
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.378
ubiquitin dependent protein catabolic process GO:0006511 206 0.362
Human
negative regulation of viral process GO:0048525 66 0.353
regulation of intracellular transport of viral material GO:1901252 2 0.329
Human
viral life cycle GO:0019058 132 0.306
cellular protein catabolic process GO:0044257 261 0.303
Human
defense response GO:0006952 315 0.300
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.295
actin nucleation GO:0045010 21 0.293
Human
movement in host environment GO:0052126 25 0.276
regulation of multi organism process GO:0043900 157 0.275
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.270
multi organism metabolic process GO:0044033 41 0.269
Human
viral process GO:0016032 146 0.267
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.266
Human
immune response activating signal transduction GO:0002757 90 0.265
protein deubiquitination GO:0016579 79 0.264
Human
defense response to virus GO:0051607 71 0.262
Human
immune response regulating signaling pathway GO:0002764 97 0.257
cellular macromolecule catabolic process GO:0044265 380 0.253
Human
negative regulation of interleukin 2 secretion GO:1900041 2 0.240
Human
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.233
Human
negative regulation of calcium ion import GO:0090281 1 0.233
Human
regulation of locomotion GO:0040012 329 0.232
regulation of cytokine production GO:0001817 232 0.231
Human Mouse
positive regulation of cytokine production GO:0001819 167 0.225
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.220
viral release from host cell GO:0019076 21 0.219
ion transmembrane transport GO:0034220 338 0.212
Human
activation of innate immune response GO:0002218 55 0.208
regulation of viral release from host cell GO:1902186 20 0.193
negative regulation of cytokine production GO:0001818 82 0.192
Human Mouse
protein monoubiquitination GO:0006513 39 0.188
Human
regulation of viral process GO:0050792 103 0.186
arp2 3 complex mediated actin nucleation GO:0034314 17 0.186
Human
transmembrane transport GO:0055085 399 0.185
Human
calcium ion import GO:0070509 23 0.184
Human
regulation of response to external stimulus GO:0032101 222 0.179
regulation of protein transport GO:0051223 213 0.176
Human
protein ubiquitination GO:0016567 314 0.174
protein catabolic process GO:0030163 325 0.172
Human Mouse
viral gene expression GO:0019080 35 0.170
Human
regulation of innate immune response GO:0045088 97 0.164
negative regulation of ion transmembrane transport GO:0034766 26 0.163
Human
innate immune response activating signal transduction GO:0002758 48 0.159
signal transduction by phosphorylation GO:0023014 297 0.156
positive regulation of immune response GO:0050778 159 0.151
regulation of defense response GO:0031347 154 0.149
regulation of ion transmembrane transport GO:0034765 132 0.148
Human
innate immune response GO:0045087 178 0.148
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.145
regulation of protein localization GO:0032880 296 0.141
Human
response to biotic stimulus GO:0009607 276 0.141
intracellular receptor signaling pathway GO:0030522 104 0.140
Human
divalent inorganic cation transport GO:0072511 158 0.136
Human
protein modification by small protein removal GO:0070646 92 0.135
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.134
negative regulation of immune system process GO:0002683 136 0.133
Human Mouse
regulation of calcium ion transport GO:0051924 79 0.131
Human
negative regulation of transport GO:0051051 176 0.130
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.129
Human
protein processing GO:0016485 226 0.128
Human
positive regulation of type i interferon production GO:0032481 20 0.128
Human
entry into host GO:0044409 25 0.128
cytokine secretion GO:0050663 64 0.123
Human
cytokine production GO:0001816 247 0.116
Human Mouse
secretion GO:0046903 254 0.113
Human
response to other organism GO:0051707 261 0.113
actin filament based process GO:0030029 224 0.110
Human
positive regulation of phosphorylation GO:0042327 394 0.109
regulation of apoptotic signaling pathway GO:2001233 175 0.106
Human
protein maturation GO:0051604 233 0.106
Human
negative regulation of protein processing GO:0010955 142 0.106
Human
negative regulation of secretion by cell GO:1903531 52 0.105
Human
positive regulation of programmed cell death GO:0043068 249 0.104
Human
positive regulation of cellular component organization GO:0051130 376 0.101
Human
pattern recognition receptor signaling pathway GO:0002221 48 0.101
negative regulation of intracellular transport of viral material GO:1901253 2 0.100
Human
protein destabilization GO:0031648 12 0.097
Human
type i interferon production GO:0032606 27 0.096
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.095
Human
immune response GO:0006955 307 0.094
vesicle mediated transport GO:0016192 371 0.094
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.093
Human
multi organism intracellular transport GO:1902583 14 0.093
Human
protein oligomerization GO:0051259 173 0.093
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.092
Human
entry into host cell GO:0030260 25 0.090
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.090
Human
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.090
Human
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.089
Human Mouse
calcium ion transport GO:0006816 147 0.089
Human
regulation of actin filament based process GO:0032970 141 0.088
Human
regulation of secretion by cell GO:1903530 177 0.088
Human
androgen receptor signaling pathway GO:0030521 34 0.086
Human
positive regulation of locomotion GO:0040017 186 0.086
Human Mouse
protein polymerization GO:0051258 71 0.086
Human
actin polymerization or depolymerization GO:0008154 56 0.085
Human
regulation of protein secretion GO:0050708 86 0.084
Human
negative regulation of protein maturation GO:1903318 142 0.084
Human
positive regulation of viral process GO:0048524 37 0.084
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.083
Human
divalent metal ion transport GO:0070838 152 0.082
Human
negative regulation of locomotion GO:0040013 118 0.082
negative regulation of proteolysis GO:0045861 132 0.082
Human
negative regulation of immune response GO:0050777 40 0.081
Human
negative regulation of viral transcription GO:0032897 23 0.080
Human
negative regulation of transmembrane transport GO:0034763 29 0.080
Human
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.079
regulation of actin polymerization or depolymerization GO:0008064 56 0.078
Human
regulation of secretion GO:0051046 194 0.078
Human
positive regulation of mapk cascade GO:0043410 190 0.078
response to virus GO:0009615 126 0.078
Human
activation of immune response GO:0002253 114 0.077
regulation of viral entry into host cell GO:0046596 17 0.077
regulation of cell cycle GO:0051726 393 0.077
Human
actin filament organization GO:0007015 128 0.077
Human
regulation of protein maturation GO:1903317 150 0.077
Human
positive regulation of actin filament polymerization GO:0030838 38 0.077
Human
metal ion transport GO:0030001 272 0.076
Human
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.076
positive regulation of cytoskeleton organization GO:0051495 83 0.075
Human
negative regulation of multi organism process GO:0043901 92 0.075
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.075
actin filament polymerization GO:0030041 45 0.074
Human
regulation of transmembrane transport GO:0034762 139 0.071
Human
negative regulation of protein metabolic process GO:0051248 391 0.071
Human
immune effector process GO:0002252 159 0.070
Human
cation transport GO:0006812 331 0.070
Human
cellular protein complex assembly GO:0043623 188 0.070
Human Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.070
positive regulation of immune system process GO:0002684 283 0.070
regulation of defense response to virus GO:0050688 33 0.070
Human
response to lipid GO:0033993 206 0.069
mapk cascade GO:0000165 288 0.069
regulation of protein catabolic process GO:0042176 155 0.067
Human Mouse
protein k48 linked ubiquitination GO:0070936 38 0.066
negative regulation of viral entry into host cell GO:0046597 12 0.065
negative regulation of phosphorus metabolic process GO:0010563 267 0.064
Human
protein k63 linked ubiquitination GO:0070534 31 0.064
viral transcription GO:0019083 35 0.064
Human
positive regulation of cell death GO:0010942 263 0.063
Human
regulation of actin filament polymerization GO:0030833 50 0.063
Human
regulation of actin cytoskeleton organization GO:0032956 116 0.062
Human
negative regulation of phosphorylation GO:0042326 174 0.062
Human
regulation of transferase activity GO:0051338 355 0.062
Human
cellular response to dna damage stimulus GO:0006974 379 0.061
positive regulation of innate immune response GO:0045089 79 0.061
positive regulation of response to external stimulus GO:0032103 88 0.061
Human
positive regulation of apoptotic process GO:0043065 246 0.060
Human
negative regulation of calcium ion transport GO:0051926 19 0.060
Human
regulation of cellular protein catabolic process GO:1903362 96 0.060
Human
interaction with host GO:0051701 42 0.060
interspecies interaction between organisms GO:0044419 156 0.059
response to external biotic stimulus GO:0043207 261 0.058
endosomal transport GO:0016197 129 0.058
Human
retrograde transport endosome to golgi GO:0042147 45 0.058
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.058
Human
regulation of type i interferon production GO:0032479 26 0.057
Human
positive regulation of cell cycle GO:0045787 140 0.057
Human
negative regulation of catalytic activity GO:0043086 335 0.056
Human
positive regulation of multi organism process GO:0043902 56 0.056
Human Mouse
regulation of immune response GO:0050776 201 0.056
negative regulation of secretion GO:0051048 58 0.056
Human
regulation of gene expression epigenetic GO:0040029 73 0.054
Human
cellular macromolecular complex assembly GO:0034622 324 0.054
Human Mouse
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.053
Human
regulation of protein stability GO:0031647 87 0.053
Human
multi organism localization GO:1902579 14 0.053
Human
regulation of intracellular transport GO:0032386 195 0.052
Human
regulation of mapk cascade GO:0043408 262 0.051
negative regulation of protein modification process GO:0031400 200 0.051
Human
negative regulation of ion transport GO:0043271 39 0.050
Human
response to oxygen containing compound GO:1901700 369 0.050
apoptotic signaling pathway GO:0097190 268 0.050
Human
regulation of protein deubiquitination GO:0090085 4 0.049
Human
negative regulation of multicellular organismal process GO:0051241 317 0.049
Human Mouse
negative regulation of protein phosphorylation GO:0001933 140 0.049
Human
negative regulation of transferase activity GO:0051348 124 0.049
Human
defense response to other organism GO:0098542 129 0.049
Human
regulation of kinase activity GO:0043549 314 0.049
Human
negative regulation of catabolic process GO:0009895 104 0.049
Human
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.049
Human
regulation of cytokine secretion GO:0050707 57 0.049
Human
actin cytoskeleton organization GO:0030036 207 0.047
Human
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.047
Human
positive regulation of defense response GO:0031349 87 0.046
negative regulation of protein ubiquitination GO:0031397 35 0.046
Human
regulation of cellular component size GO:0032535 82 0.045
Human
negative regulation of interleukin 2 production GO:0032703 7 0.045
Human
regulation of proteolysis GO:0030162 293 0.045
Human
regulation of response to biotic stimulus GO:0002831 55 0.045
regulation of actin filament length GO:0030832 56 0.045
Human
response to bacterium GO:0009617 144 0.045
negative regulation of cellular protein metabolic process GO:0032269 353 0.044
Human
regulation of establishment of protein localization GO:0070201 242 0.043
Human
regulation of cellular component biogenesis GO:0044087 281 0.043
Human Mouse
cellular response to molecule of bacterial origin GO:0071219 62 0.043
transport of virus GO:0046794 14 0.042
Human
positive regulation of organelle organization GO:0010638 195 0.041
Human
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.040
Human
multi organism transport GO:0044766 14 0.039
Human
positive regulation of proteolysis GO:0045862 142 0.038
positive regulation of response to biotic stimulus GO:0002833 18 0.037
Human
adaptive immune response GO:0002250 49 0.037
Human
regulation of protein complex assembly GO:0043254 147 0.037
Human Mouse
post embryonic development GO:0009791 2 0.037
negative regulation of tumor necrosis factor production GO:0032720 20 0.037
Human Mouse
regulation of cytoskeleton organization GO:0051493 177 0.037
Human
negative regulation of cell death GO:0060548 345 0.036
positive regulation of apoptotic signaling pathway GO:2001235 70 0.036
Human
negative regulation of protein catabolic process GO:0042177 59 0.035
Human
regulation of protein processing GO:0070613 150 0.035
Human
positive regulation of protein polymerization GO:0032273 45 0.034
Human
positive regulation of transport GO:0051050 336 0.034
negative regulation of programmed cell death GO:0043069 321 0.034
negative regulation of protein secretion GO:0050709 29 0.034
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.034
Human
positive regulation of immune effector process GO:0002699 40 0.034
Human
positive regulation of interferon beta production GO:0032728 17 0.033
regulation of cell motility GO:2000145 299 0.033
cellular response to lipopolysaccharide GO:0071222 57 0.033
negative regulation of apoptotic process GO:0043066 316 0.033
determination of adult lifespan GO:0008340 2 0.033
regulation of cellular response to stress GO:0080135 244 0.032
cellular response to oxygen containing compound GO:1901701 276 0.031
negative regulation of cellular protein catabolic process GO:1903363 38 0.031
Human
regulation of protein kinase activity GO:0045859 289 0.031
Human
protein trimerization GO:0070206 20 0.031
multicellular organismal aging GO:0010259 3 0.031
cellular response to virus GO:0098586 9 0.031
Human
regulation of cell migration GO:0030334 289 0.031
regulation of interleukin 2 production GO:0032663 19 0.030
Human
cellular amino acid metabolic process GO:0006520 116 0.030
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.030
Human
regulation of protein polymerization GO:0032271 63 0.030
Human
negative regulation of protein transport GO:0051224 75 0.030
Human
response to cytokine GO:0034097 232 0.029
regulation of metal ion transport GO:0010959 120 0.028
Human
response to lipopolysaccharide GO:0032496 70 0.028
protein secretion GO:0009306 98 0.028
Human
proteasomal protein catabolic process GO:0010498 176 0.028
negative regulation of protein kinase activity GO:0006469 98 0.028
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.028
cellular response to biotic stimulus GO:0071216 71 0.028
regulation of immune effector process GO:0002697 91 0.027
Human
positive regulation of catabolic process GO:0009896 310 0.027
Mouse
negative regulation of adaptive immune response GO:0002820 9 0.027
Human
chromatin organization GO:0006325 351 0.027
single organism cellular localization GO:1902580 332 0.026
response to abiotic stimulus GO:0009628 336 0.026
regulation of cellular component movement GO:0051270 334 0.025
rna interference GO:0016246 4 0.025
intracellular protein transport GO:0006886 270 0.024
regulation of ion transport GO:0043269 189 0.024
Human
cellular response to lipid GO:0071396 127 0.024
mitotic cell cycle GO:0000278 326 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
response to molecule of bacterial origin GO:0002237 82 0.024
glycoprotein metabolic process GO:0009100 110 0.024
negative regulation of cellular catabolic process GO:0031330 83 0.023
Human
nucleotide catabolic process GO:0009166 408 0.023
protein localization to organelle GO:0033365 280 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
regulation of anatomical structure size GO:0090066 101 0.023
Human
female gamete generation GO:0007292 2 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
locomotory behavior GO:0007626 1 0.022
intrinsic apoptotic signaling pathway GO:0097193 127 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
neuromuscular junction development GO:0007528 3 0.021
chemical homeostasis GO:0048878 306 0.021
single organism membrane organization GO:0044802 268 0.020
nervous system development GO:0007399 293 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
purine nucleotide biosynthetic process GO:0006164 84 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.020
purine containing compound catabolic process GO:0072523 411 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
regulation of cell cycle process GO:0010564 266 0.020
negative regulation of gene expression epigenetic GO:0045814 19 0.019
Human
carbohydrate metabolic process GO:0005975 207 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
regulation of tumor necrosis factor production GO:0032680 43 0.019
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
interleukin 2 production GO:0032623 20 0.019
Human
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.019
Human
secretion by cell GO:0032940 226 0.019
Human
membrane organization GO:0061024 292 0.019
response to nitrogen compound GO:1901698 184 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
negative regulation of kinase activity GO:0033673 106 0.018
Human
organophosphate catabolic process GO:0046434 430 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
dna repair GO:0006281 198 0.018
nucleoside catabolic process GO:0009164 408 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
oogenesis GO:0048477 2 0.018
cell growth GO:0016049 160 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
nuclear transport GO:0051169 179 0.017
macromolecule glycosylation GO:0043413 63 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
cell development GO:0048468 328 0.017
positive regulation of protein transport GO:0051222 135 0.017
interferon gamma production GO:0032609 39 0.017
Human
positive regulation of intracellular protein transport GO:0090316 76 0.017
regulation of response to dna damage stimulus GO:2001020 94 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
cellular component morphogenesis GO:0032989 314 0.017
negative regulation of cell cycle GO:0045786 193 0.017
segmentation GO:0035282 4 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
rna processing GO:0006396 255 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
regulation of cell differentiation GO:0045595 393 0.016
cellular ketone metabolic process GO:0042180 80 0.016
wnt signaling pathway GO:0016055 156 0.016
protein localization to nucleus GO:0034504 136 0.016
rig i signaling pathway GO:0039529 7 0.016
Human
mrna metabolic process GO:0016071 175 0.016
adult locomotory behavior GO:0008344 1 0.016
entry into other organism involved in symbiotic interaction GO:0051828 25 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
negative regulation of cytokine secretion GO:0050710 20 0.016
Human
protein targeting GO:0006605 187 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
peripheral nervous system development GO:0007422 2 0.015
atp metabolic process GO:0046034 176 0.015
intracellular transport of virus GO:0075733 14 0.015
Human
regulation of protein localization to nucleus GO:1900180 85 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
regeneration GO:0031099 4 0.015
spermatid differentiation GO:0048515 4 0.015
response to radiation GO:0009314 151 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
chromatin modification GO:0016568 298 0.015
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
regulation of cell development GO:0060284 161 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
positive regulation of cellular component movement GO:0051272 181 0.014
organic acid biosynthetic process GO:0016053 97 0.014
cell morphogenesis GO:0000902 296 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
regulation of cellular amine metabolic process GO:0033238 11 0.014
positive regulation of cell motility GO:2000147 177 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
positive regulation of protein catabolic process GO:0045732 75 0.013
Mouse
regulation of cell growth GO:0001558 135 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
cytoplasmic transport GO:0016482 379 0.013
positive regulation of transferase activity GO:0051347 227 0.013
positive regulation of interferon alpha production GO:0032727 11 0.013
lipid metabolic process GO:0006629 381 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
amine metabolic process GO:0009308 44 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
Mouse
regulation of adaptive immune response GO:0002819 33 0.013
Human
fibroblast proliferation GO:0048144 33 0.013
neurogenesis GO:0022008 169 0.013
central nervous system development GO:0007417 123 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
ribonucleoprotein complex assembly GO:0022618 78 0.013
response to tumor necrosis factor GO:0034612 76 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
negative regulation of intracellular transport GO:0032387 60 0.013
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
organelle assembly GO:0070925 176 0.013
positive regulation of cell migration GO:0030335 172 0.013
mitotic cell cycle process GO:1903047 286 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
negative regulation of developmental process GO:0051093 247 0.013
translation GO:0006412 132 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
memory GO:0007613 3 0.013
positive regulation of developmental process GO:0051094 314 0.013
small molecule biosynthetic process GO:0044283 157 0.012
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
tumor necrosis factor production GO:0032640 43 0.012
Human Mouse
ncrna metabolic process GO:0034660 108 0.012
positive regulation of intracellular transport GO:0032388 104 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
spermatid development GO:0007286 4 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
circulatory system development GO:0072359 262 0.012
ras protein signal transduction GO:0007265 73 0.012
lipid biosynthetic process GO:0008610 177 0.012
rna catabolic process GO:0006401 71 0.012
regulation of rig i signaling pathway GO:0039535 6 0.012
Human
regulation of synaptic plasticity GO:0048167 3 0.012
viral entry into host cell GO:0046718 24 0.012
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.012
cellular lipid metabolic process GO:0044255 303 0.012
system process GO:0003008 349 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
actin filament based movement GO:0030048 17 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
compound eye development GO:0048749 1 0.012
ion homeostasis GO:0050801 230 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
atp catabolic process GO:0006200 157 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
rhythmic behavior GO:0007622 2 0.011
negative regulation of gliogenesis GO:0014014 3 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
cell adhesion GO:0007155 325 0.011
actin mediated cell contraction GO:0070252 12 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of growth GO:0040008 165 0.011
tissue regeneration GO:0042246 3 0.011
cell fate determination GO:0001709 3 0.011
hindbrain development GO:0030902 3 0.011
cellular response to external stimulus GO:0071496 111 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
cellular homeostasis GO:0019725 196 0.011
nerve development GO:0021675 4 0.011
positive regulation of kinase activity GO:0033674 204 0.011
blastoderm segmentation GO:0007350 2 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
microtubule based process GO:0007017 210 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
tripartite regional subdivision GO:0007351 2 0.011
response to uv GO:0009411 73 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
zymogen activation GO:0031638 70 0.011
response to dsrna GO:0043331 25 0.011
regulation of peptidase activity GO:0052547 180 0.011
autophagy GO:0006914 88 0.011
oocyte differentiation GO:0009994 2 0.011

TRIM5 disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.033
musculoskeletal system disease DOID:17 223 0.033
muscle tissue disease DOID:66 113 0.033
disease of metabolism DOID:0014667 295 0.027
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
myopathy DOID:423 104 0.019
muscular dystrophy DOID:9884 51 0.019
central nervous system disease DOID:331 186 0.016
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
limb girdle muscular dystrophy DOID:11724 25 0.015
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
inherited metabolic disorder DOID:655 242 0.014
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.013
organ system cancer DOID:0050686 164 0.013
acquired metabolic disease DOID:0060158 58 0.012
immune system disease DOID:2914 155 0.011