IMP

Process View

Homo sapiens

19 genes annotated in human

Multi-species View

regulation of interleukin 2 production

GO:0032663

Any process that modulates the frequency, rate, or extent of interleukin-2 production.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 2 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 2 production" (in gray)

Name	Description	Probability	Func Analog Organism
TRAF6	TNF receptor-associated factor 6	0.772
LAT	linker for activation of T cells	0.623
TRIM21	tripartite motif containing 21	0.605	Human
BIRC3	baculoviral IAP repeat containing 3	0.598
CCR5	chemokine (C-C motif) receptor 5	0.563
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.544
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.489
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.488
MED15	mediator complex subunit 15	0.334
HDAC7	histone deacetylase 7	0.287
CD40	CD40 molecule, TNF receptor superfamily member 5	0.231
BCL10	B-cell CLL/lymphoma 10	0.205
CCL4	chemokine (C-C motif) ligand 4	0.199	Human
CD247	CD247 molecule	0.196
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.194
LCK	lymphocyte-specific protein tyrosine kinase	0.182
IL2RB	interleukin 2 receptor, beta	0.136
IRAK1	interleukin-1 receptor-associated kinase 1	0.127
TRAF3	TNF receptor-associated factor 3	0.115	Human
IL1R1	interleukin 1 receptor, type I	0.110
TNF	tumor necrosis factor	0.109
CCL22	chemokine (C-C motif) ligand 22	0.104	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.096
NMI	N-myc (and STAT) interactor	0.091
NUMBL	numb homolog (Drosophila)-like	0.089
CCR7	chemokine (C-C motif) receptor 7	0.088
CD86	CD86 molecule	0.081
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.077
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.075
MEF2C	myocyte enhancer factor 2C	0.072
CXCL10	chemokine (C-X-C motif) ligand 10	0.070
IRF1	interferon regulatory factor 1	0.069	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.069
NCOR1	nuclear receptor corepressor 1	0.068
CD80	CD80 molecule	0.063
IDE	insulin-degrading enzyme	0.062
PML	promyelocytic leukemia	0.058
ZNF263	zinc finger protein 263	0.058
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.057
ZMYND11	zinc finger, MYND-type containing 11	0.057
IRAK2	interleukin-1 receptor-associated kinase 2	0.055
ICAM1	intercellular adhesion molecule 1	0.055
TRAF1	TNF receptor-associated factor 1	0.054	Human
IRF9	interferon regulatory factor 9	0.054
PRKD2	protein kinase D2	0.050	Mouse
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.050	Human
GRAP2	GRB2-related adaptor protein 2	0.049
MYD88	myeloid differentiation primary response gene (88)	0.047
IL1RN	interleukin 1 receptor antagonist	0.047	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.046
KAT5	K(lysine) acetyltransferase 5	0.045
PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like	0.044
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.044
TRIM32	tripartite motif containing 32	0.044
EGFR	epidermal growth factor receptor	0.040
CXCL9	chemokine (C-X-C motif) ligand 9	0.038
CCL8	chemokine (C-C motif) ligand 8	0.037	Human
IL8	interleukin 8	0.034
BCL6	B-cell CLL/lymphoma 6	0.034
CCL13	chemokine (C-C motif) ligand 13	0.032	Human
CCL2	chemokine (C-C motif) ligand 2	0.030	Human
TRIM5	tripartite motif containing 5	0.030	Human
TRAF5	TNF receptor-associated factor 5	0.030	Human
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.030
NCOR2	nuclear receptor corepressor 2	0.029
IL1R2	interleukin 1 receptor, type II	0.029
HDAC9	histone deacetylase 9	0.027	Human
CD83	CD83 molecule	0.026	Mouse
IL7R	interleukin 7 receptor	0.026
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.026	Human
PLK3	polo-like kinase 3	0.026
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.025
HDAC3	histone deacetylase 3	0.025
PELI3	pellino homolog 3 (Drosophila)	0.024
CCR4	chemokine (C-C motif) receptor 4	0.023
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.023
DAXX	death-domain associated protein	0.023
FOXP3	forkhead box P3	0.021
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.021
CD48	CD48 molecule	0.021
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.020
TRIM17	tripartite motif containing 17	0.020	Human
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.020
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.020
PIAS4	protein inhibitor of activated STAT, 4	0.020
CCL7	chemokine (C-C motif) ligand 7	0.020	Human
CCL3	chemokine (C-C motif) ligand 3	0.020	Human
ATXN1	ataxin 1	0.020
TRIM39	tripartite motif containing 39	0.019	Human
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.019
RIN1	Ras and Rab interactor 1	0.019
CD1C	CD1c molecule	0.019
DPP4	dipeptidyl-peptidase 4	0.019
IRF8	interferon regulatory factor 8	0.018	Human
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.018
IL10	interleukin 10	0.018
TRAF2	TNF receptor-associated factor 2	0.018
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.017
C19orf66	chromosome 19 open reading frame 66	0.017
TRIM26	tripartite motif containing 26	0.017
CCL19	chemokine (C-C motif) ligand 19	0.017	Human
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.016
IL1B	interleukin 1, beta	0.015
SFN	stratifin	0.015
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.015
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.015
STAP2	signal transducing adaptor family member 2	0.014
SELE	selectin E	0.014
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.014
SMAD1	SMAD family member 1	0.014
TLR2	toll-like receptor 2	0.014
IL6	interleukin 6 (interferon, beta 2)	0.013
IFNG	interferon, gamma	0.013
MEF2A	myocyte enhancer factor 2A	0.013
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.013
HDAC4	histone deacetylase 4	0.013	Human
ZNF473	zinc finger protein 473	0.013
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.013
LY86	lymphocyte antigen 86	0.012
PPARA	peroxisome proliferator-activated receptor alpha	0.012
CCL11	chemokine (C-C motif) ligand 11	0.012	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.012
ATM	ataxia telangiectasia mutated	0.012
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.012
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.012
CCL20	chemokine (C-C motif) ligand 20	0.012	Human
SH2D1A	SH2 domain containing 1A	0.012
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.011
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.011
CCL1	chemokine (C-C motif) ligand 1	0.011	Human
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.011
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.011
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.011
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.011
ZNF512B	zinc finger protein 512B	0.011
CCL17	chemokine (C-C motif) ligand 17	0.011	Human
BLNK	B-cell linker	0.011
CD2	CD2 molecule	0.010
SYK	spleen tyrosine kinase	0.010
CLEC10A	C-type lectin domain family 10, member A	0.010
CCR1	chemokine (C-C motif) receptor 1	0.010