|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
1.000
|
Mouse |
|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
1.000
|
|
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
1.000
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
1.000
|
Mouse |
|
|
skeletal muscle satellite cell proliferation
|
GO:0014841 |
1 |
1.000
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
1.000
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
1.000
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
1.000
|
Mouse |
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
1.000
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
1.000
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
1.000
|
Mouse |
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
1.000
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
1.000
|
Mouse |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
1.000
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
1.000
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
1.000
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
1.000
|
|
|
|
protein processing
|
GO:0016485 |
226 |
1.000
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
1.000
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
1.000
|
Human Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
1.000
|
Human Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
1.000
|
|
|
|
response to cobalt ion
|
GO:0032025 |
1 |
1.000
|
Rat |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
1.000
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
1.000
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
1.000
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
1.000
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
1.000
|
Mouse |
|
|
activation induced cell death of t cells
|
GO:0006924 |
2 |
1.000
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
1.000
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
1.000
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
1.000
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
1.000
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
1.000
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
1.000
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
1.000
|
|
|
|
necroptotic process
|
GO:0070266 |
16 |
1.000
|
Mouse |
|
|
necrotic cell death
|
GO:0070265 |
21 |
1.000
|
Mouse |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
1.000
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
1.000
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
1.000
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
1.000
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.999
|
Human Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.999
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.999
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.999
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.999
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.999
|
|
|
|
positive regulation of nik nf kappab signaling
|
GO:1901224 |
10 |
0.999
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.999
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.999
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
7 |
0.999
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.998
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.998
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
11 |
0.998
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.997
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.997
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.997
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.997
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.997
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.996
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.996
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.996
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
6 |
0.996
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.996
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.996
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.996
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.996
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.995
|
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.995
|
|
|
|
positive regulation of endothelial cell apoptotic process
|
GO:2000353 |
8 |
0.995
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.994
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.994
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.994
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.992
|
Human Mouse |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.992
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.992
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.992
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.991
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.991
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.991
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.990
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.990
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.989
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.989
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.989
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.988
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.987
|
Human |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.986
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.986
|
|
|
|
regulation of cellular extravasation
|
GO:0002691 |
8 |
0.985
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.982
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.981
|
Human |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.981
|
Mouse |
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.981
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.980
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.976
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.976
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.976
|
Human |
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.975
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.974
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.974
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.972
|
Human |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.972
|
Human |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.972
|
|
|
|
positive regulation of bone resorption
|
GO:0045780 |
2 |
0.971
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.971
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.968
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.966
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.966
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.965
|
Rat |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.964
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.963
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.963
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.962
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.961
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.961
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.960
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.958
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.955
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.955
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.948
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.947
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.947
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.947
|
|
|
|
activated t cell proliferation
|
GO:0050798 |
13 |
0.946
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.946
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.945
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.945
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.944
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.942
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.941
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.940
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.938
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.932
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.929
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.929
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.929
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.926
|
Human |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.925
|
Human |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.925
|
Human |
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.923
|
|
|
|
spleen development
|
GO:0048536 |
1 |
0.923
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.923
|
Human |
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.921
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.919
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.918
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.916
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.915
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.915
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.912
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.911
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.910
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.903
|
Human |
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.899
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.897
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.896
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.896
|
Human Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.893
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.891
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.883
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.883
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.882
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.881
|
Human |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.881
|
|
|
|
system process
|
GO:0003008 |
349 |
0.881
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.880
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.879
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
8 |
0.878
|
|
|
|
response to water
|
GO:0009415 |
2 |
0.875
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.867
|
Human |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.861
|
Human |
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.857
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.854
|
Mouse |
|
|
striated muscle adaptation
|
GO:0014888 |
4 |
0.853
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.852
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.852
|
Human |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.850
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.843
|
Rat |
|
|
regulation of necrotic cell death
|
GO:0010939 |
9 |
0.835
|
Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.829
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.828
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.824
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.822
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
4 |
0.820
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.813
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.812
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.812
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.811
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.804
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.794
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.791
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.779
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.766
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.765
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.759
|
Human |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.758
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.752
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.738
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.735
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.733
|
|
|
|
regulation of satellite cell proliferation
|
GO:0014842 |
1 |
0.728
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.726
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.720
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.719
|
Human |
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.715
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.712
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.709
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.709
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.708
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.707
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.707
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.704
|
|
|
|
neuron cellular homeostasis
|
GO:0070050 |
3 |
0.703
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.703
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.702
|
Human |
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.701
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.697
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.688
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.665
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.663
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.661
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.661
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.659
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.659
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
3 |
0.658
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.657
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.653
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.646
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.645
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.633
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.631
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.628
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.612
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.606
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.599
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.598
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.593
|
Human Mouse |
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.593
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.587
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.585
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.582
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.582
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.580
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.580
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.577
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.576
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.567
|
|
|
|
positive regulation of protein homooligomerization
|
GO:0032464 |
7 |
0.564
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.562
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.560
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.552
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.549
|
Human |
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.547
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.547
|
Rat |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.547
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.538
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.538
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.529
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.528
|
|
|
|
pigment metabolic process
|
GO:0042440 |
16 |
0.526
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.523
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.521
|
Human |
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.516
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.510
|
Human |
|
|
brain development
|
GO:0007420 |
97 |
0.505
|
Human |
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.500
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.500
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.489
|
Rat |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.486
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.481
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
8 |
0.480
|
|
|
|
regulation of cell killing
|
GO:0031341 |
22 |
0.479
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.475
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.469
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.450
|
|
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.446
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.446
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
12 |
0.436
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.436
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.435
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.435
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.420
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.411
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
2 |
0.408
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.406
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.403
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.396
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.391
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.391
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.391
|
Rat |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.389
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.387
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.386
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.383
|
|
|
|
cellular response to water stimulus
|
GO:0071462 |
1 |
0.371
|
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.368
|
|
|
|
fas signaling pathway
|
GO:0036337 |
3 |
0.367
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.366
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.364
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.361
|
|
|
|
head development
|
GO:0060322 |
108 |
0.359
|
Human |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.357
|
Human |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.357
|
Human |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.355
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.352
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.347
|
|
|
|
cellular response to estrogen stimulus
|
GO:0071391 |
16 |
0.344
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.341
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.339
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.338
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.335
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.333
|
Human |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.332
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.332
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.329
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.327
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.320
|
|
|
|
negative regulation of nf kappab import into nucleus
|
GO:0042347 |
12 |
0.318
|
|
|
|
regulation of skeletal muscle cell proliferation
|
GO:0014857 |
1 |
0.315
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.314
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.309
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.308
|
Mouse |
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.307
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.299
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.298
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.297
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.296
|
Human |
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.296
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.295
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.294
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.290
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.286
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.284
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.284
|
Human |
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.282
|
Rat |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.281
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.280
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.278
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.278
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.275
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.270
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.266
|
Human |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
22 |
0.264
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.261
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.258
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.253
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.252
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
159 |
0.251
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.243
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.241
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.240
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.240
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.237
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.236
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.235
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.235
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.230
|
|
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.228
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.227
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.226
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.225
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.224
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.224
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.223
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.222
|
Human |
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.218
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.218
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.216
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.216
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.214
|
Human |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.212
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.211
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.211
|
Mouse |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.207
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.205
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.203
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.202
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.201
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.201
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.199
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.198
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.197
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
11 |
0.196
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.194
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.191
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.188
|
|
|
|
ripoptosome assembly
|
GO:0097343 |
1 |
0.186
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.184
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.183
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.182
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.179
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.177
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.175
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.171
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.171
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.171
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.169
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.168
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.168
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.168
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.168
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.167
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.166
|
|
|
|
regulation of protein homooligomerization
|
GO:0032462 |
11 |
0.165
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.165
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
3 |
0.165
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.162
|
Human |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.161
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.159
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.156
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.156
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.156
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.153
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.149
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.149
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.146
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.145
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.144
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.142
|
Rat |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.140
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.140
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.139
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.137
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.135
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
11 |
0.135
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.134
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.134
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.134
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.132
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.128
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.128
|
Mouse |
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.128
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.128
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.124
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.124
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.123
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.122
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.121
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.121
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.120
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.120
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.120
|
Rat |
|
|
t cell migration
|
GO:0072678 |
16 |
0.119
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.118
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.117
|
|
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
11 |
0.116
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.116
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.113
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.111
|
Human |
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.111
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.111
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
7 |
0.109
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.109
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.108
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.108
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.108
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.107
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.107
|
|
|
|
carbohydrate derivative transport
|
GO:1901264 |
20 |
0.106
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.106
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.106
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.105
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.105
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.103
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.103
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.102
|
Rat |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.102
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.101
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.099
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.098
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.098
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.097
|
Rat |
|
|
positive regulation of cellular extravasation
|
GO:0002693 |
3 |
0.096
|
|
|
|
response to cycloheximide
|
GO:0046898 |
1 |
0.094
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.093
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.093
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.091
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.091
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
12 |
0.090
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.090
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.089
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.089
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.089
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.086
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.086
|
|
|
|
skeletal muscle cell proliferation
|
GO:0014856 |
1 |
0.086
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.085
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.082
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.082
|
|
