IMP
Process View
dna damage response signal transduction by p53 class mediator
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dna damage response signal transduction by p53 class mediator"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BRCA1 | breast cancer 1, early onset | 1.000 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.983 | Human | |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.977 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.977 | ||
| ATM | ataxia telangiectasia mutated | 0.976 | ||
| TP53 | tumor protein p53 | 0.951 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.940 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.923 | Human | |
| CREBBP | CREB binding protein | 0.910 | ||
| NBN | nibrin | 0.904 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.900 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.899 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.838 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.780 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.774 | ||
| E2F7 | E2F transcription factor 7 | 0.766 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.738 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.727 | ||
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.712 | ||
| E2F8 | E2F transcription factor 8 | 0.689 | Human | |
| PML | promyelocytic leukemia | 0.683 | Mouse | |
| CDK2 | cyclin-dependent kinase 2 | 0.671 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.666 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.585 | ||
| H2AFX | H2A histone family, member X | 0.581 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.572 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.552 | ||
| EP300 | E1A binding protein p300 | 0.549 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.535 | Human | |
| BCAS2 | breast carcinoma amplified sequence 2 | 0.522 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.494 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.471 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.463 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.458 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.407 | ||
| TWIST1 | twist homolog 1 (Drosophila) | 0.393 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.387 | ||
| IER3 | immediate early response 3 | 0.384 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.382 | Human | |
| GSK3B | glycogen synthase kinase 3 beta | 0.378 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.358 | ||
| CCNE1 | cyclin E1 | 0.354 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.344 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.341 | ||
| APAF1 | apoptotic peptidase activating factor 1 | 0.339 | ||
| DAXX | death-domain associated protein | 0.320 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.313 | ||
| CCND3 | cyclin D3 | 0.311 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.282 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.280 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.271 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.270 | Human | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.262 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.258 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.252 | ||
| MYH7B | myosin, heavy chain 7B, cardiac muscle, beta | 0.249 | ||
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.248 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.242 | Human | |
| TNIP2 | TNFAIP3 interacting protein 2 | 0.240 | ||
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.239 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.238 | ||
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.234 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.212 | ||
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.211 | ||
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.208 | ||
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.207 | ||
| SP110 | SP110 nuclear body protein | 0.205 | Human | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.198 | Human | |
| MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 0.188 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.185 | ||
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.181 | ||
| HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 0.173 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.172 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.172 | Human | |
| HDAC1 | histone deacetylase 1 | 0.167 | ||
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.165 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.163 | ||
| MAPK3 | mitogen-activated protein kinase 3 | 0.159 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.158 | ||
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.154 | ||
| LRDD | leucine-rich repeats and death domain containing | 0.146 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.144 | ||
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.143 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.132 | ||
| PLK1 | polo-like kinase 1 | 0.132 | ||
| HIC2 | hypermethylated in cancer 2 | 0.131 | ||
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.125 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.121 | ||
| EGFR | epidermal growth factor receptor | 0.119 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.118 | Human | |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.115 | ||
| RB1 | retinoblastoma 1 | 0.114 | ||
| SP100 | SP100 nuclear antigen | 0.114 | ||
| RUNX1 | runt-related transcription factor 1 | 0.113 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.107 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.105 | ||
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.103 | ||
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.099 | ||
| PRKCA | protein kinase C, alpha | 0.097 | ||
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.097 | ||
| NMI | N-myc (and STAT) interactor | 0.096 | ||
| BTRC | beta-transducin repeat containing | 0.095 | ||
| WRN | Werner syndrome, RecQ helicase-like | 0.093 | ||
| CDK11B | cyclin-dependent kinase 11B | 0.092 | ||
| KIAA1267 | KIAA1267 | 0.086 | ||
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.085 | ||
| BCL2L1 | BCL2-like 1 | 0.085 | ||
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.084 | ||
| EGR1 | early growth response 1 | 0.083 | ||
| RIN1 | Ras and Rab interactor 1 | 0.080 | ||
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.078 | ||
| ZNF420 | zinc finger protein 420 | 0.078 | ||
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.077 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.076 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.075 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.073 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.073 | Human | |
| YAP1 | Yes-associated protein 1 | 0.070 | ||
| MSN | moesin | 0.068 | ||
| H3F3C | H3 histone, family 3C | 0.067 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.066 | ||
| WWOX | WW domain containing oxidoreductase | 0.066 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.065 | ||
| MKRN1 | makorin ring finger protein 1 | 0.065 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.064 | ||
| MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) | 0.064 | ||
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.063 | ||
| MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.063 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.062 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.062 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.062 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.061 | ||
| SIRT1 | sirtuin 1 | 0.060 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.060 | ||
| CCND2 | cyclin D2 | 0.059 | ||
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.058 | ||
| BID | BH3 interacting domain death agonist | 0.058 | ||
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.058 | ||
| RNF20 | ring finger protein 20 | 0.058 | ||
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.057 | ||
| EEF2K | eukaryotic elongation factor-2 kinase | 0.057 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.056 | ||
| CCND1 | cyclin D1 | 0.055 | ||
| SMAD7 | SMAD family member 7 | 0.054 | ||
| GATA2 | GATA binding protein 2 | 0.054 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.054 | Human | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.054 | ||
| CREB1 | cAMP responsive element binding protein 1 | 0.053 | ||
| COASY | CoA synthase | 0.053 | ||
| DUSP1 | dual specificity phosphatase 1 | 0.052 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.050 | ||
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.049 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.049 | ||
| SPRR2A | small proline-rich protein 2A | 0.047 | ||
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 0.047 | ||
| LIMD1 | LIM domains containing 1 | 0.047 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.047 | ||
| BAX | BCL2-associated X protein | 0.046 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.045 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.045 | ||
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | 0.044 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.044 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.043 | ||
| PAX3 | paired box 3 | 0.043 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.043 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.042 | ||
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.041 | ||
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.041 | ||
| PKM2 | pyruvate kinase, muscle | 0.041 | ||
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.041 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.041 | ||
| BARD1 | BRCA1 associated RING domain 1 | 0.040 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.040 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.039 | ||
| RIOK3 | RIO kinase 3 (yeast) | 0.039 | ||
| USP42 | ubiquitin specific peptidase 42 | 0.038 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.038 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.037 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.037 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.037 | ||
| POLH | polymerase (DNA directed), eta | 0.036 | ||
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.036 | Fly | |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.036 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.035 | ||
| ETS1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.035 | ||
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.035 | ||
| S100A4 | S100 calcium binding protein A4 | 0.035 | ||
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.035 | ||
| AR | androgen receptor | 0.034 | ||
| MLL4 | myeloid/lymphoid or mixed-lineage leukemia 4 | 0.034 | ||
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.033 | ||
| IFI35 | interferon-induced protein 35 | 0.033 | ||
| NOTCH1 | notch 1 | 0.033 | ||
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 0.033 | ||
| IRF1 | interferon regulatory factor 1 | 0.033 | ||
| MEN1 | multiple endocrine neoplasia I | 0.032 | ||
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.032 | ||
| MYOD1 | myogenic differentiation 1 | 0.032 | ||
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.031 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.031 | Human | |
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.031 | ||
| RAD51C | RAD51 homolog C (S. cerevisiae) | 0.031 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.031 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.030 | ||
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.030 | ||
| KRT5 | keratin 5 | 0.030 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.030 | ||
| OSGEP | O-sialoglycoprotein endopeptidase | 0.029 | ||
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.029 | ||
| CASP8AP2 | caspase 8 associated protein 2 | 0.029 | ||
| RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.029 | ||
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.028 | ||
| ELK1 | ELK1, member of ETS oncogene family | 0.028 | ||
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.028 | ||
| CWC15 | CWC15 spliceosome-associated protein homolog (S. cerevisiae) | 0.028 | ||
| FAM118B | family with sequence similarity 118, member B | 0.028 | ||
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.028 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.028 | ||
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.028 | ||
| LIMK2 | LIM domain kinase 2 | 0.028 | ||
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa | 0.027 | ||
| BLM | Bloom syndrome, RecQ helicase-like | 0.027 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.027 | ||
| SMAD2 | SMAD family member 2 | 0.027 | ||
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.027 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.026 | ||
| BIRC5 | baculoviral IAP repeat containing 5 | 0.026 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.026 | ||
| TSC22D1 | TSC22 domain family, member 1 | 0.026 | ||
| DUSP3 | dual specificity phosphatase 3 | 0.026 | ||
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.025 | ||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.025 | ||
| H3F3B | H3 histone, family 3B (H3.3B) | 0.025 | ||
| TOX4 | TOX high mobility group box family member 4 | 0.025 | ||
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | 0.025 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.025 | ||
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.025 | ||
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.025 | ||
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.024 | ||
| SMAD6 | SMAD family member 6 | 0.024 | ||
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.024 | ||
| E2F1 | E2F transcription factor 1 | 0.024 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.024 | ||
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.024 | ||
| CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.024 | ||
| MSH5 | mutS homolog 5 (E. coli) | 0.024 | ||
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.024 | ||
| DZIP1 | DAZ interacting protein 1 | 0.024 | ||
| BBC3 | BCL2 binding component 3 | 0.024 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.024 | ||
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) | 0.023 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.023 | ||
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.023 | ||
| C11orf16 | chromosome 11 open reading frame 16 | 0.023 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.023 | ||
| JUNB | jun B proto-oncogene | 0.023 | ||
| BAK1 | BCL2-antagonist/killer 1 | 0.023 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.023 | ||
| FAM117B | family with sequence similarity 117, member B | 0.023 | ||
| ENO1 | enolase 1, (alpha) | 0.023 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.022 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.022 | Human | |
| CUL7 | cullin 7 | 0.022 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.022 | ||
| BAD | BCL2-associated agonist of cell death | 0.022 | ||
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | 0.022 | ||
| RBBP5 | retinoblastoma binding protein 5 | 0.022 | ||
| PCNA | proliferating cell nuclear antigen | 0.022 | ||
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.021 | ||
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.021 | ||
| PLSCR1 | phospholipid scramblase 1 | 0.021 | ||
| CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.021 | ||
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.021 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.021 | ||
| MARCKSL1 | MARCKS-like 1 | 0.020 | ||
| MAGEA2 | melanoma antigen family A, 2 | 0.020 | ||
| TCF12 | transcription factor 12 | 0.020 | ||
| MEST | mesoderm specific transcript homolog (mouse) | 0.020 | ||
| FAM20C | family with sequence similarity 20, member C | 0.020 | ||
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.020 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.020 | ||
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.020 | ||
| SMAD1 | SMAD family member 1 | 0.020 | ||
| SPTBN4 | spectrin, beta, non-erythrocytic 4 | 0.020 | ||
| VEZF1 | vascular endothelial zinc finger 1 | 0.020 | ||
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.020 | ||
| ZNF746 | zinc finger protein 746 | 0.020 | ||
| WASF1 | WAS protein family, member 1 | 0.020 | ||
| SGOL1 | shugoshin-like 1 (S. pombe) | 0.019 | ||
| CTBP1 | C-terminal binding protein 1 | 0.019 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.019 | ||
| HSPA8 | heat shock 70kDa protein 8 | 0.019 | ||
| WDYHV1 | WDYHV motif containing 1 | 0.019 | ||
| RBM4B | RNA binding motif protein 4B | 0.019 | ||
| C19orf46 | chromosome 19 open reading frame 46 | 0.019 | ||
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.019 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.019 | ||
| PDX1 | pancreatic and duodenal homeobox 1 | 0.019 | ||
| A2M | alpha-2-macroglobulin | 0.018 | ||
| RNF8 | ring finger protein 8 | 0.018 | ||
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.018 | ||
| ING4 | inhibitor of growth family, member 4 | 0.018 | ||
| FBN3 | fibrillin 3 | 0.018 | ||
| NGFR | nerve growth factor receptor | 0.018 | ||
| CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.018 | ||
| SP140L | SP140 nuclear body protein-like | 0.018 | Human | |
| DUSP6 | dual specificity phosphatase 6 | 0.018 | ||
| FZD5 | frizzled homolog 5 (Drosophila) | 0.018 | ||
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.018 | ||
| RNF19A | ring finger protein 19A | 0.018 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.017 | ||
| PIM1 | pim-1 oncogene | 0.017 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.017 | ||
| PAX6 | paired box 6 | 0.017 | ||
| SAP30 | Sin3A-associated protein, 30kDa | 0.017 | ||
| C17orf79 | chromosome 17 open reading frame 79 | 0.017 | ||
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.017 | ||
| CDC25B | cell division cycle 25 homolog B (S. pombe) | 0.017 | ||
| ADSS | adenylosuccinate synthase | 0.017 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.017 | ||
| TMSB4X | thymosin beta 4, X-linked | 0.017 | ||
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.017 | ||
| CCNA1 | cyclin A1 | 0.017 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.017 | ||
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.017 | ||
| KAT5 | K(lysine) acetyltransferase 5 | 0.017 | ||
| FOXG1 | forkhead box G1 | 0.017 | ||
| CTSS | cathepsin S | 0.017 | ||
| MAPK7 | mitogen-activated protein kinase 7 | 0.017 | ||
| TTN | titin | 0.017 | ||
| MAPT | microtubule-associated protein tau | 0.017 | ||
| PHF11 | PHD finger protein 11 | 0.017 | ||
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.016 | ||
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.016 | ||
| APRT | adenine phosphoribosyltransferase | 0.016 | ||
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.016 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.016 | ||
| TCAP | titin-cap (telethonin) | 0.016 | ||
| SMS | spermine synthase | 0.016 | ||
| BCL2A1 | BCL2-related protein A1 | 0.016 | ||
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.016 | ||
| DMC1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | 0.016 | ||
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.016 | ||
| TRIM22 | tripartite motif containing 22 | 0.016 | ||
| PGK1 | phosphoglycerate kinase 1 | 0.016 | ||
| TERF2 | telomeric repeat binding factor 2 | 0.016 | ||
| NEK1 | NIMA (never in mitosis gene a)-related kinase 1 | 0.016 | ||
| ARRB2 | arrestin, beta 2 | 0.016 | ||
| KRT6C | keratin 6C | 0.016 | ||
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.016 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.015 | ||
| IP6K2 | inositol hexakisphosphate kinase 2 | 0.015 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.015 | ||
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa | 0.015 | ||
| GATA4 | GATA binding protein 4 | 0.015 | ||
| UBA7 | ubiquitin-like modifier activating enzyme 7 | 0.015 | ||
| RAI1 | retinoic acid induced 1 | 0.015 | ||
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.015 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.015 | ||
| LMO4 | LIM domain only 4 | 0.015 | ||
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.015 | ||
| MED1 | mediator complex subunit 1 | 0.015 | ||
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.015 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.015 | ||
| SALL2 | sal-like 2 (Drosophila) | 0.015 | ||
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 | 0.015 | ||
| BECN1 | beclin 1, autophagy related | 0.015 | ||
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.015 | ||
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.015 | Mouse | |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.015 | ||
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 0.014 | ||
| SF1 | splicing factor 1 | 0.014 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.014 | ||
| BANP | BTG3 associated nuclear protein | 0.014 | ||
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | 0.014 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.014 | ||
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.014 | ||
| HIST1H3B | histone cluster 1, H3b | 0.014 | ||
| SCAF8 | SR-related CTD-associated factor 8 | 0.014 | ||
| TRIM38 | tripartite motif containing 38 | 0.014 | ||
| FOSL2 | FOS-like antigen 2 | 0.014 | ||
| PPAT | phosphoribosyl pyrophosphate amidotransferase | 0.014 | ||
| DUSP7 | dual specificity phosphatase 7 | 0.014 | ||
| LHX5 | LIM homeobox 5 | 0.014 | ||
| MLKL | mixed lineage kinase domain-like | 0.014 | ||
| EZR | ezrin | 0.014 | ||
| CSNK1D | casein kinase 1, delta | 0.014 | ||
| FANCE | Fanconi anemia, complementation group E | 0.014 | ||
| MDFI | MyoD family inhibitor | 0.014 | ||
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.014 | ||
| CLEC3B | C-type lectin domain family 3, member B | 0.014 | ||
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 0.014 | ||
| ZFP36L1 | zinc finger protein 36, C3H type-like 1 | 0.014 | ||
| ING5 | inhibitor of growth family, member 5 | 0.014 | Human | |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.014 | ||
| CTBP2 | C-terminal binding protein 2 | 0.014 | ||
| VASP | vasodilator-stimulated phosphoprotein | 0.014 | ||
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.013 | Human | |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.013 | ||
| TRIM21 | tripartite motif containing 21 | 0.013 | ||
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 0.013 | ||
| PBK | PDZ binding kinase | 0.013 | ||
| ZIC3 | Zic family member 3 (odd-paired homolog, Drosophila) | 0.013 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.013 | ||
| RNF11 | ring finger protein 11 | 0.013 | ||
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.013 | ||
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.013 | ||
| CDK5 | cyclin-dependent kinase 5 | 0.013 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.013 | ||
| VIM | vimentin | 0.013 | ||
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.013 | ||
| SOX1 | SRY (sex determining region Y)-box 1 | 0.013 | Human | |
| RYBP | RING1 and YY1 binding protein | 0.013 | ||
| GORASP1 | golgi reassembly stacking protein 1, 65kDa | 0.013 | ||
| BRCA2 | breast cancer 2, early onset | 0.013 | Mouse | |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.013 | ||
| CDK4 | cyclin-dependent kinase 4 | 0.013 | ||
| PHOX2A | paired-like homeobox 2a | 0.013 | ||
| NUCB2 | nucleobindin 2 | 0.013 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.013 | ||
| HOXD8 | homeobox D8 | 0.013 | ||
| TP73 | tumor protein p73 | 0.013 | Human | |
| HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.012 | ||
| MSI1 | musashi homolog 1 (Drosophila) | 0.012 | ||
| FES | feline sarcoma oncogene | 0.012 | ||
| PDLIM1 | PDZ and LIM domain 1 | 0.012 | ||
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.012 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.012 | ||
| SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 0.012 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.012 | Human Fly | |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.012 | Human | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.012 | ||
| CARD16 | caspase recruitment domain family, member 16 | 0.012 | ||
| HNRNPCL1 | heterogeneous nuclear ribonucleoprotein C-like 1 | 0.012 | ||
| MAPK9 | mitogen-activated protein kinase 9 | 0.012 | ||
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.012 | ||
| GSTM4 | glutathione S-transferase mu 4 | 0.012 | ||
| MRPS23 | mitochondrial ribosomal protein S23 | 0.012 | ||
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.012 | ||
| MXI1 | MAX interactor 1 | 0.012 | ||
| TRIM14 | tripartite motif containing 14 | 0.012 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.012 | ||
| SOX4 | SRY (sex determining region Y)-box 4 | 0.012 | ||
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 0.012 | ||
| MT1A | metallothionein 1A | 0.012 | ||
| E2F2 | E2F transcription factor 2 | 0.012 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.012 | ||
| HAND2 | heart and neural crest derivatives expressed 2 | 0.012 | Human | |
| TNS4 | tensin 4 | 0.012 | ||
| POU3F1 | POU class 3 homeobox 1 | 0.012 | ||
| ABI2 | abl-interactor 2 | 0.012 | ||
| HOXD12 | homeobox D12 | 0.012 | ||
| ALDOA | aldolase A, fructose-bisphosphate | 0.012 | ||
| SOX11 | SRY (sex determining region Y)-box 11 | 0.012 | Human | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.012 | ||
| MSH6 | mutS homolog 6 (E. coli) | 0.012 | ||
| CCDC106 | coiled-coil domain containing 106 | 0.011 | ||
| SOX8 | SRY (sex determining region Y)-box 8 | 0.011 | Human | |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 0.011 | ||
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.011 | ||
| NUDCD2 | NudC domain containing 2 | 0.011 | ||
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | 0.011 | ||
| IER2 | immediate early response 2 | 0.011 | ||
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.011 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.011 | ||
| IRS4 | insulin receptor substrate 4 | 0.011 | ||
| CUX1 | cut-like homeobox 1 | 0.011 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.011 | ||
| S1PR5 | sphingosine-1-phosphate receptor 5 | 0.011 | ||
| LYL1 | lymphoblastic leukemia derived sequence 1 | 0.011 | Human | |
| OPTN | optineurin | 0.011 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.011 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.011 | ||
| TTC19 | tetratricopeptide repeat domain 19 | 0.011 | ||
| SFRP5 | secreted frizzled-related protein 5 | 0.011 | ||
| PRPF19 | PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) | 0.011 | Zebrafish | |
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.011 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.011 | ||
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | 0.011 | ||
| RPS27L | ribosomal protein S27-like | 0.011 | ||
| PRKCE | protein kinase C, epsilon | 0.011 | ||
| SAMD9 | sterile alpha motif domain containing 9 | 0.011 | ||
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.011 | ||
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 0.011 | ||
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.011 | ||
| PTRH2 | peptidyl-tRNA hydrolase 2 | 0.011 | ||
| FOXB1 | forkhead box B1 | 0.011 | ||
| MAGED1 | melanoma antigen family D, 1 | 0.011 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.011 | ||
| HIC1 | hypermethylated in cancer 1 | 0.011 | Mouse | |
| GDF6 | growth differentiation factor 6 | 0.011 | ||
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.011 | ||
| KIAA0020 | KIAA0020 | 0.011 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.010 | ||
| MTA2 | metastasis associated 1 family, member 2 | 0.010 | ||
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.010 | ||
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.010 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.010 | ||
| CCNG2 | cyclin G2 | 0.010 | ||
| SOX14 | SRY (sex determining region Y)-box 14 | 0.010 | ||
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' | 0.010 | ||
| IL8 | interleukin 8 | 0.010 | ||
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.010 | ||
| HOXD13 | homeobox D13 | 0.010 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.010 | ||
| SATB1 | SATB homeobox 1 | 0.010 | ||
| SIAH2 | seven in absentia homolog 2 (Drosophila) | 0.010 | ||
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.010 | ||
| SCGN | secretagogin, EF-hand calcium binding protein | 0.010 | ||
| UTP18 | UTP18, small subunit (SSU) processome component, homolog (yeast) | 0.010 | ||
| S100A8 | S100 calcium binding protein A8 | 0.010 | ||
| PPP1R13B | protein phosphatase 1, regulatory (inhibitor) subunit 13B | 0.010 | ||
| CELF1 | CUGBP, Elav-like family member 1 | 0.010 | ||
| ANGPT2 | angiopoietin 2 | 0.010 | ||
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.010 | ||
| VSX1 | visual system homeobox 1 | 0.010 | ||
| RLF | rearranged L-myc fusion | 0.010 | ||
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | 0.010 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.010 | ||
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.010 |