Homo sapiens

64 known processes

TNK2

tyrosine kinase, non-receptor, 2

(Aliases: ACK,FLJ44758,ACK1,FLJ45547,p21cdc42Hs)

TNK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of kinase activity GO:0043549 314 0.891
Human
regulation of cellular component size GO:0032535 82 0.887
Human
ribonucleoside catabolic process GO:0042454 406 0.863
positive regulation of protein kinase activity GO:0045860 190 0.857
Human
regulation of actin filament polymerization GO:0030833 50 0.816
Human
positive regulation of protein phosphorylation GO:0001934 313 0.815
regulation of nucleoside metabolic process GO:0009118 209 0.791
regulation of gtp catabolic process GO:0033124 180 0.777
actin filament based process GO:0030029 224 0.776
Human
regulation of receptor mediated endocytosis GO:0048259 32 0.761
cellular component morphogenesis GO:0032989 314 0.756
Human
guanosine containing compound metabolic process GO:1901068 244 0.750
ribonucleoside triphosphate metabolic process GO:0009199 412 0.744
regulation of actin polymerization or depolymerization GO:0008064 56 0.730
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.717
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.703
guanosine containing compound catabolic process GO:1901069 239 0.683
actin cytoskeleton organization GO:0030036 207 0.679
Human
positive regulation of neurogenesis GO:0050769 49 0.678
Human
positive regulation of gtpase activity GO:0043547 166 0.673
ribonucleotide catabolic process GO:0009261 405 0.664
nucleoside triphosphate catabolic process GO:0009143 394 0.652
rho protein signal transduction GO:0007266 26 0.635
negative regulation of cellular component organization GO:0051129 235 0.634
keratinization GO:0031424 2 0.629
gtp metabolic process GO:0046039 239 0.624
purine nucleoside catabolic process GO:0006152 398 0.608
nucleoside phosphate catabolic process GO:1901292 412 0.601
regulation of cell projection organization GO:0031344 107 0.580
Human
gtp catabolic process GO:0006184 237 0.577
regulation of protein complex assembly GO:0043254 147 0.543
Human
actin filament polymerization GO:0030041 45 0.532
Human
glycosyl compound catabolic process GO:1901658 413 0.525
regulation of transferase activity GO:0051338 355 0.523
Human
actin polymerization or depolymerization GO:0008154 56 0.518
Human
cell projection organization GO:0030030 252 0.516
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.510
regulation of actin cytoskeleton organization GO:0032956 116 0.505
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.490
regulation of protein kinase activity GO:0045859 289 0.485
Human
vesicle mediated transport GO:0016192 371 0.479
positive regulation of actin filament polymerization GO:0030838 38 0.464
Human
activation of protein kinase activity GO:0032147 90 0.445
Human
nucleotide catabolic process GO:0009166 408 0.443
purine ribonucleoside catabolic process GO:0046130 398 0.439
positive regulation of transferase activity GO:0051347 227 0.437
Human
regulation of cell shape GO:0008360 48 0.426
Human
purine containing compound catabolic process GO:0072523 411 0.410
positive regulation of developmental process GO:0051094 314 0.405
Human
regulation of cellular component biogenesis GO:0044087 281 0.403
Human
neuron projection development GO:0031175 106 0.396
Human
small gtpase mediated signal transduction GO:0007264 78 0.392
regulation of nucleotide catabolic process GO:0030811 205 0.389
membrane organization GO:0061024 292 0.375
vesicle organization GO:0016050 62 0.373
purine nucleotide catabolic process GO:0006195 405 0.369
cellular ketone metabolic process GO:0042180 80 0.356
nucleoside catabolic process GO:0009164 408 0.341
ribonucleoside triphosphate catabolic process GO:0009203 391 0.333
regulation of gtpase activity GO:0043087 180 0.331
organophosphate catabolic process GO:0046434 430 0.324
regulation of protein polymerization GO:0032271 63 0.314
Human
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.313
ras protein signal transduction GO:0007265 73 0.313
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.308
locomotory behavior GO:0007626 1 0.307
cell development GO:0048468 328 0.280
Human Fly
cell cell adhesion mediated by cadherin GO:0044331 4 0.273
g protein coupled receptor signaling pathway GO:0007186 207 0.270
positive regulation of gtp catabolic process GO:0033126 166 0.269
nervous system development GO:0007399 293 0.266
Human
cell morphogenesis GO:0000902 296 0.263
Human
positive regulation of phosphorylation GO:0042327 394 0.260
regulation of cytoskeleton organization GO:0051493 177 0.260
Human
positive regulation of catabolic process GO:0009896 310 0.257
mitotic cell cycle process GO:1903047 286 0.242
cellular protein complex assembly GO:0043623 188 0.241
Human
memory GO:0007613 3 0.225
positive regulation of hydrolase activity GO:0051345 331 0.224
positive regulation of cytoskeleton organization GO:0051495 83 0.213
Human
generation of neurons GO:0048699 152 0.210
Human
regulation of actin filament length GO:0030832 56 0.203
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.201
positive regulation of nucleotide metabolic process GO:0045981 230 0.199
protein polymerization GO:0051258 71 0.196
Human
cellular response to endogenous stimulus GO:0071495 336 0.196
Human
regulation of cellular response to stress GO:0080135 244 0.194
Human
positive regulation of cellular component organization GO:0051130 376 0.191
Human
cellular macromolecular complex assembly GO:0034622 324 0.190
Human
neurogenesis GO:0022008 169 0.189
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.189
positive regulation of map kinase activity GO:0043406 80 0.188
regulation of neurogenesis GO:0050767 82 0.184
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.180
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.178
mitotic cell cycle GO:0000278 326 0.173
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.173
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.173
carbohydrate metabolic process GO:0005975 207 0.171
positive regulation of protein complex assembly GO:0031334 86 0.168
Human
positive regulation of nervous system development GO:0051962 54 0.168
Human
post embryonic development GO:0009791 2 0.166
positive regulation of nucleoside metabolic process GO:0045979 186 0.163
regulation of rho protein signal transduction GO:0035023 79 0.161
membrane tubulation GO:0097320 12 0.158
neuron development GO:0048666 113 0.155
Human
regulation of jnk cascade GO:0046328 73 0.155
Human
neuromuscular junction development GO:0007528 3 0.155
protein autophosphorylation GO:0046777 123 0.155
Human
neurotrophin trk receptor signaling pathway GO:0048011 4 0.151
positive regulation of transport GO:0051050 336 0.147
central nervous system development GO:0007417 123 0.147
taxis GO:0042330 157 0.142
positive regulation of organelle organization GO:0010638 195 0.140
Human
endocytosis GO:0006897 159 0.137
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.136
Human
regulation of cellular amine metabolic process GO:0033238 11 0.135
positive regulation of cell migration GO:0030335 172 0.134
Human
hair follicle morphogenesis GO:0031069 2 0.133
cell cell signaling GO:0007267 155 0.132
regulation of cellular ketone metabolic process GO:0010565 50 0.128
regulation of vesicle mediated transport GO:0060627 130 0.127
positive regulation of kinase activity GO:0033674 204 0.127
Human
positive regulation of cell projection organization GO:0031346 64 0.126
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.126
Human
glycerolipid metabolic process GO:0046486 107 0.125
regulation of cell morphogenesis GO:0022604 153 0.124
Human
epithelium development GO:0060429 227 0.123
Fly
single organism membrane organization GO:0044802 268 0.122
mitotic nuclear division GO:0007067 119 0.119
cell morphogenesis involved in differentiation GO:0000904 144 0.115
endosomal transport GO:0016197 129 0.115
positive regulation of cell development GO:0010720 92 0.113
Human
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.113
negative regulation of neuron projection development GO:0010977 15 0.112
regulation of endocytosis GO:0030100 72 0.111
negative regulation of catalytic activity GO:0043086 335 0.110
positive regulation of cellular catabolic process GO:0031331 284 0.109
brain development GO:0007420 97 0.107
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.105
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.104
synaptic vesicle endocytosis GO:0048488 2 0.103
convergent extension involved in gastrulation GO:0060027 1 0.102
cytoskeleton dependent cytokinesis GO:0061640 22 0.101
positive regulation of ras gtpase activity GO:0032320 117 0.101
purine ribonucleoside metabolic process GO:0046128 437 0.099
cellular amine metabolic process GO:0044106 41 0.099
response to hormone GO:0009725 175 0.097
Human
actin filament organization GO:0007015 128 0.097
Human
positive regulation of proteolysis GO:0045862 142 0.096
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.096
regulation of cell development GO:0060284 161 0.092
Human
establishment of neuroblast polarity GO:0045200 1 0.086
regulation of nucleotide metabolic process GO:0006140 269 0.085
response to abiotic stimulus GO:0009628 336 0.085
peptidyl tyrosine modification GO:0018212 170 0.082
plasma membrane organization GO:0007009 115 0.082
sensory perception of pain GO:0019233 4 0.082
negative regulation of cell size GO:0045792 3 0.081
regulation of anatomical structure size GO:0090066 101 0.080
Human
regulation of protein localization GO:0032880 296 0.080
lipid metabolic process GO:0006629 381 0.080
positive regulation of neuron projection development GO:0010976 34 0.080
Human
dephosphorylation GO:0016311 209 0.077
negative regulation of phosphate metabolic process GO:0045936 267 0.076
adult locomotory behavior GO:0008344 1 0.076
response to drug GO:0042493 81 0.075
ephrin receptor signaling pathway GO:0048013 15 0.075
Human
head development GO:0060322 108 0.074
epithelial cell migration GO:0010631 119 0.074
Human
spermatid development GO:0007286 4 0.074
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.074
positive regulation of rac gtpase activity GO:0032855 31 0.073
positive regulation of stress activated mapk cascade GO:0032874 60 0.073
Human
regulation of immune response GO:0050776 201 0.073
regulation of stress activated mapk cascade GO:0032872 84 0.070
Human
protein dephosphorylation GO:0006470 81 0.068
jnk cascade GO:0007254 80 0.068
Human
microtubule cytoskeleton organization GO:0000226 176 0.068
vasodilation GO:0042311 4 0.067
regulation of ras protein signal transduction GO:0046578 155 0.067
regulation of vasodilation GO:0042312 4 0.065
immune response activating signal transduction GO:0002757 90 0.063
stress activated mapk cascade GO:0051403 93 0.062
Human
defense response GO:0006952 315 0.060
regulation of anatomical structure morphogenesis GO:0022603 286 0.060
Human
biological adhesion GO:0022610 331 0.060
Human
axon development GO:0061564 34 0.060
transferrin transport GO:0033572 4 0.060
endochondral bone morphogenesis GO:0060350 3 0.060
receptor mediated endocytosis GO:0006898 84 0.059
regulation of ras gtpase activity GO:0032318 128 0.059
positive regulation of jnk cascade GO:0046330 52 0.059
Human
ossification GO:0001503 121 0.059
Human
response to organonitrogen compound GO:0010243 156 0.058
Human
cation transport GO:0006812 331 0.058
Human
regulation of nervous system development GO:0051960 88 0.058
Human
regulation of neuron differentiation GO:0045664 70 0.058
Human
positive regulation of rho gtpase activity GO:0032321 56 0.058
immune response GO:0006955 307 0.058
positive regulation of small gtpase mediated signal transduction GO:0051057 12 0.057
peptidyl serine modification GO:0018209 106 0.057
cellular response to oxygen containing compound GO:1901701 276 0.055
Human
regulation of cell adhesion GO:0030155 166 0.055
Human
neurotransmitter secretion GO:0007269 4 0.055
regulation of mapk cascade GO:0043408 262 0.055
Human
organelle localization GO:0051640 84 0.055
membrane budding GO:0006900 28 0.054
vacuole organization GO:0007033 44 0.054
secretion GO:0046903 254 0.054
neuron projection morphogenesis GO:0048812 50 0.053
cell division GO:0051301 168 0.053
associative learning GO:0008306 1 0.053
neuroblast division GO:0055057 1 0.053
negative regulation of cell death GO:0060548 345 0.052
Human Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.052
retinal ganglion cell axon guidance GO:0031290 2 0.051
regulation of potassium ion transport GO:0043266 24 0.051
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.050
Human
receptor internalization GO:0031623 43 0.050
dendritic spine morphogenesis GO:0060997 3 0.050
response to mechanical stimulus GO:0009612 51 0.050
cell type specific apoptotic process GO:0097285 125 0.049
negative regulation of protein kinase activity GO:0006469 98 0.049
cellular lipid metabolic process GO:0044255 303 0.049
positive regulation of nucleotide catabolic process GO:0030813 185 0.049
response to organic cyclic compound GO:0014070 204 0.048
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.048
regulation of jun kinase activity GO:0043506 27 0.048
actin nucleation GO:0045010 21 0.048
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.048
sensory perception of mechanical stimulus GO:0050954 37 0.047
positive regulation of endocytosis GO:0045807 42 0.047
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.047
negative regulation of protein phosphorylation GO:0001933 140 0.046
mapk cascade GO:0000165 288 0.046
Human
membrane depolarization GO:0051899 26 0.046
negative regulation of phosphorus metabolic process GO:0010563 267 0.046
regulation of mitosis GO:0007088 63 0.045
positive regulation of neuron differentiation GO:0045666 40 0.045
Human
regulation of leukocyte activation GO:0002694 115 0.045
trivalent inorganic cation transport GO:0072512 4 0.045
metal ion transport GO:0030001 272 0.044
Human
astrocyte cell migration GO:0043615 1 0.043
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.042
osteoblast differentiation GO:0001649 92 0.042
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.042
Human
response to oxygen containing compound GO:1901700 369 0.042
Human
single organismal cell cell adhesion GO:0016337 148 0.042
Human
epithelial cell development GO:0002064 34 0.042
nuclear division GO:0000280 128 0.040
purine ribonucleotide catabolic process GO:0009154 404 0.040
receptor transactivation GO:0035624 4 0.040
endochondral ossification GO:0001958 1 0.039
transition metal ion transport GO:0000041 23 0.039
negative regulation of kinase activity GO:0033673 106 0.039
regulation of locomotion GO:0040012 329 0.039
Human
regulation of cellular component movement GO:0051270 334 0.039
Human
response to steroid hormone GO:0048545 80 0.038
regulation of protein catabolic process GO:0042176 155 0.038
Human
neurological system process GO:0050877 163 0.037
response to inorganic substance GO:0010035 127 0.037
apoptotic signaling pathway GO:0097190 268 0.037
regulation of cell projection assembly GO:0060491 47 0.037
regulation of actin filament based process GO:0032970 141 0.036
Human
cellular response to hormone stimulus GO:0032870 125 0.036
Human
response to nitrogen compound GO:1901698 184 0.036
Human
regulation of protein kinase b signaling GO:0051896 61 0.035
Human
establishment of organelle localization GO:0051656 59 0.035
metencephalon development GO:0022037 2 0.035
cellular response to peptide GO:1901653 59 0.035
Human
negative regulation of transferase activity GO:0051348 124 0.035
ion transmembrane transport GO:0034220 338 0.035
regulation of map kinase activity GO:0043405 108 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
regulation of proteolysis GO:0030162 293 0.034
Human
cytokinesis GO:0000910 96 0.034
synaptic transmission GO:0007268 61 0.034
cell projection assembly GO:0030031 126 0.034
cell migration involved in gastrulation GO:0042074 1 0.033
regulation of lymphocyte activation GO:0051249 103 0.033
negative regulation of protein modification process GO:0031400 200 0.033
positive regulation of mapk cascade GO:0043410 190 0.033
Human
positive regulation of cell death GO:0010942 263 0.033
activation of mapk activity GO:0000187 45 0.033
regulation of nuclear division GO:0051783 65 0.032
leukocyte proliferation GO:0070661 74 0.032
circulatory system process GO:0003013 113 0.032
response to cytokine GO:0034097 232 0.032
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
cellular response to nitrogen compound GO:1901699 144 0.032
Human
regulation of cell migration GO:0030334 289 0.031
Human
chemotaxis GO:0006935 157 0.031
regulation of growth GO:0040008 165 0.031
positive regulation of cell growth GO:0030307 48 0.031
monovalent inorganic cation transport GO:0015672 128 0.031
Human
protein catabolic process GO:0030163 325 0.031
Human
asymmetric neuroblast division GO:0055059 1 0.030
response to other organism GO:0051707 261 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.030
cellular response to organic cyclic compound GO:0071407 127 0.030
regulation of cell junction assembly GO:1901888 29 0.030
lung alveolus development GO:0048286 4 0.030
cell growth GO:0016049 160 0.030
regulation of epidermis development GO:0045682 19 0.029
cerebellar cortex development GO:0021695 1 0.029
activation of mapkk activity GO:0000186 18 0.029
cell projection morphogenesis GO:0048858 129 0.029
negative regulation of programmed cell death GO:0043069 321 0.029
Human Fly
leukocyte activation GO:0045321 164 0.029
regulation of protein tyrosine kinase activity GO:0061097 36 0.029
endosome organization GO:0007032 20 0.028
organelle fission GO:0048285 149 0.028
regulation of neuron projection development GO:0010975 57 0.028
Human
erbb signaling pathway GO:0038127 44 0.028
ion homeostasis GO:0050801 230 0.028
organic hydroxy compound metabolic process GO:1901615 147 0.027
antigen receptor mediated signaling pathway GO:0050851 38 0.027
receptor metabolic process GO:0043112 81 0.027
glycerophospholipid metabolic process GO:0006650 84 0.027
carbohydrate derivative biosynthetic process GO:1901137 207 0.027
inositol lipid mediated signaling GO:0048017 55 0.027
Human
golgi organization GO:0007030 38 0.027
lymphocyte activation GO:0046649 133 0.026
establishment or maintenance of neuroblast polarity GO:0045196 1 0.026
hindbrain development GO:0030902 3 0.025
syncytium formation by plasma membrane fusion GO:0000768 2 0.025
positive regulation of immune system process GO:0002684 283 0.025
stress activated protein kinase signaling cascade GO:0031098 94 0.025
Human
cellular response to organonitrogen compound GO:0071417 124 0.024
Human
neuron differentiation GO:0030182 138 0.024
Human
regeneration GO:0031099 4 0.024
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.024
Human
neurotrophin signaling pathway GO:0038179 8 0.024
negative regulation of protein complex assembly GO:0031333 43 0.024
regulation of intracellular transport GO:0032386 195 0.023
positive regulation of protein ubiquitination GO:0031398 53 0.023
morphogenesis of a branching structure GO:0001763 21 0.023
cerebellum development GO:0021549 2 0.023
potassium ion transport GO:0006813 62 0.023
Human
cytokinetic process GO:0032506 12 0.023
leukocyte migration GO:0050900 107 0.023
positive regulation of protein polymerization GO:0032273 45 0.023
Human
regulation of response to external stimulus GO:0032101 222 0.022
positive regulation of apoptotic signaling pathway GO:2001235 70 0.022
regulation of cellular protein catabolic process GO:1903362 96 0.022
Human
phagocytosis GO:0006909 42 0.022
positive regulation of cell adhesion GO:0045785 84 0.022
Human
phagosome lysosome fusion GO:0090385 4 0.022
epidermis development GO:0008544 59 0.022
hemopoiesis GO:0030097 180 0.022
Human
maintenance of cell polarity GO:0030011 2 0.022
regulation of cell differentiation GO:0045595 393 0.021
Human
molting cycle GO:0042303 28 0.021
regulation of erbb signaling pathway GO:1901184 27 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
protein secretion GO:0009306 98 0.021
retrograde transport endosome to golgi GO:0042147 45 0.021
actin cytoskeleton reorganization GO:0031532 37 0.021
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.021
growth GO:0040007 202 0.020
cell substrate junction assembly GO:0007044 35 0.020
system process GO:0003008 349 0.020
phospholipid metabolic process GO:0006644 99 0.020
negative regulation of mitochondrial depolarization GO:0051902 2 0.020
negative regulation of growth GO:0045926 97 0.019
platelet derived growth factor receptor signaling pathway GO:0048008 14 0.019
rac protein signal transduction GO:0016601 12 0.019
cell part morphogenesis GO:0032990 137 0.019
microtubule based process GO:0007017 210 0.019
spermatid differentiation GO:0048515 4 0.019
Fly
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.019
integrin mediated signaling pathway GO:0007229 32 0.019
Human
regulation of receptor activity GO:0010469 47 0.019
determination of adult lifespan GO:0008340 2 0.019
regulation of potassium ion transmembrane transport GO:1901379 20 0.019
positive regulation of jun kinase activity GO:0043507 23 0.019
cell chemotaxis GO:0060326 112 0.018
multicellular organismal aging GO:0010259 3 0.018
positive regulation of cell activation GO:0050867 81 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
Human
axonogenesis GO:0007409 31 0.018
peptidyl serine phosphorylation GO:0018105 101 0.018
negative regulation of cell motility GO:2000146 104 0.018
negative regulation of immune system process GO:0002683 136 0.018
Human
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of membrane potential GO:0042391 95 0.017
positive regulation of actin filament bundle assembly GO:0032233 25 0.017
regulation of metal ion transport GO:0010959 120 0.017
Human
lamellipodium organization GO:0097581 30 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.017
neuron projection regeneration GO:0031102 1 0.017
arp2 3 complex mediated actin nucleation GO:0034314 17 0.017
negative regulation of cell projection organization GO:0031345 22 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
zymogen activation GO:0031638 70 0.017
response to growth factor GO:0070848 205 0.016
Human
positive regulation of immune response GO:0050778 159 0.016
single organism cellular localization GO:1902580 332 0.016
regulation of protein binding GO:0043393 66 0.016
nucleus localization GO:0051647 1 0.016
negative regulation of organelle organization GO:0010639 126 0.016
actin filament based movement GO:0030048 17 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
metal ion homeostasis GO:0055065 169 0.016
dendritic spine organization GO:0097061 4 0.016
negative regulation of nervous system development GO:0051961 28 0.016
regulation of actin nucleation GO:0051125 10 0.016
innate immune response GO:0045087 178 0.015
pinocytosis GO:0006907 8 0.015
transmembrane transport GO:0055085 399 0.015
positive regulation of synaptic transmission GO:0050806 4 0.015
activation of cysteine type endopeptidase activity GO:0097202 57 0.015
cellular response to acid chemical GO:0071229 44 0.015
Human
positive regulation of programmed cell death GO:0043068 249 0.015
positive regulation of vasodilation GO:0045909 4 0.015
collateral sprouting GO:0048668 2 0.015
actin mediated cell contraction GO:0070252 12 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
Human
negative regulation of cell differentiation GO:0045596 171 0.014
Human
positive regulation of apoptotic process GO:0043065 246 0.014
epithelial tube morphogenesis GO:0060562 38 0.014
neuron projection guidance GO:0097485 12 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
Human
respiratory tube development GO:0030323 20 0.014
neuroblast proliferation GO:0007405 4 0.014
ovulation cycle GO:0042698 9 0.014
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.014
immune response regulating signaling pathway GO:0002764 97 0.014
single organism behavior GO:0044708 28 0.014
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 6 0.014
negative regulation of cell matrix adhesion GO:0001953 14 0.014
polysaccharide biosynthetic process GO:0000271 27 0.014
establishment of nucleus localization GO:0040023 1 0.014
iron ion transport GO:0006826 12 0.014
autophagy GO:0006914 88 0.014
epidermal growth factor receptor signaling pathway GO:0007173 39 0.014
neuron death GO:0070997 65 0.014
regulation of protein localization to cell surface GO:2000008 15 0.014
glycerolipid biosynthetic process GO:0045017 51 0.014
regulation of endothelial cell migration GO:0010594 67 0.014
Human
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.014
exocytosis GO:0006887 71 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.013
myeloid cell differentiation GO:0030099 117 0.013
Human
regulation of peptidase activity GO:0052547 180 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
regulation of t cell activation GO:0050863 77 0.013
epidermis morphogenesis GO:0048730 3 0.013
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.013
adherens junction organization GO:0034332 36 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
response to increased oxygen levels GO:0036296 4 0.013
divalent metal ion transport GO:0070838 152 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
Human
immune effector process GO:0002252 159 0.013
asymmetric stem cell division GO:0098722 1 0.013
embryo development GO:0009790 123 0.013
Fly
myoblast fusion GO:0007520 1 0.013
positive regulation of metalloenzyme activity GO:0048554 2 0.013
regulation of natural killer cell proliferation GO:0032817 4 0.013
central nervous system neuron axonogenesis GO:0021955 3 0.013
regulation of ion homeostasis GO:2000021 73 0.012
positive regulation of synapse structural plasticity GO:0051835 2 0.012
endomembrane system organization GO:0010256 196 0.012
response to lipid GO:0033993 206 0.012
Human
regulation of immune effector process GO:0002697 91 0.012
positive regulation of gliogenesis GO:0014015 4 0.012
negative regulation of cytoskeleton organization GO:0051494 45 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.012
Human
maintenance of location GO:0051235 112 0.012
protein processing GO:0016485 226 0.012
establishment of vesicle localization GO:0051650 23 0.012

TNK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.107
disease of metabolism DOID:0014667 295 0.051
central nervous system disease DOID:331 186 0.034
nervous system disease DOID:863 431 0.034
inherited metabolic disorder DOID:655 242 0.033
neurodegenerative disease DOID:1289 102 0.031
carbohydrate metabolism disease DOID:0050013 32 0.029
acquired metabolic disease DOID:0060158 58 0.029
immune system disease DOID:2914 155 0.028
musculoskeletal system disease DOID:17 223 0.027
muscular disease DOID:0080000 114 0.023
muscle tissue disease DOID:66 113 0.023
diabetes mellitus DOID:9351 31 0.019
glucose metabolism disease DOID:4194 32 0.019
type 2 diabetes mellitus DOID:9352 28 0.015
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.012