|
|
vesicle organization
|
GO:0016050 |
62 |
1.000
|
Human |
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
1.000
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
1.000
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.999
|
Fly |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.999
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.998
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.997
|
Fly |
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.996
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.996
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.996
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.996
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.995
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.993
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.992
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.989
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.987
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.983
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.982
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.981
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.981
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.980
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.977
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.976
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.971
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.968
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.967
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.965
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.962
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.962
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.961
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.954
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.953
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.952
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.949
|
Human |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
5 |
0.948
|
Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.941
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.932
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.930
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.929
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.924
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.920
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.905
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.894
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.891
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.889
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.878
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.874
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.867
|
Mouse Fly |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.864
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.862
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.860
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.847
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.845
|
Human Yeast Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.843
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.843
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.843
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.841
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.837
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.835
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.825
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.821
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.805
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.802
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.800
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.777
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.770
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.746
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.745
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.699
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.697
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.696
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.688
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.686
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.686
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.686
|
Fly |
|
|
endosome organization
|
GO:0007032 |
20 |
0.678
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.674
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.644
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.629
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.616
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.613
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.608
|
Fly |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.605
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.578
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.568
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.568
|
Yeast |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.565
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.559
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.553
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.551
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.542
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.537
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.534
|
Fly |
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.533
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.525
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.522
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.521
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.519
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.514
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.507
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.504
|
Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.496
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.496
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.484
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.474
|
Yeast Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.467
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.459
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.459
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.456
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.450
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.449
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.447
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.441
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.441
|
|
|
|
positive regulation of protein localization to cell surface
|
GO:2000010 |
6 |
0.440
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.439
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.427
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.406
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.402
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.400
|
|
|
|
protein lipid complex subunit organization
|
GO:0071825 |
24 |
0.388
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.375
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.366
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.360
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.345
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.326
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.326
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.303
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.298
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.297
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.296
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.293
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.287
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.287
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.286
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.279
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.278
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.274
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.272
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.270
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.270
|
Yeast |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.257
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.255
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.252
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.246
|
Fly |
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.245
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.234
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.231
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.223
|
Fly |
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.216
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.215
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.210
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.202
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.199
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.197
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.195
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.192
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.188
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.187
|
|
|
|
phagosome lysosome fusion
|
GO:0090385 |
4 |
0.186
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.182
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.176
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.172
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.172
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.168
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.161
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.158
|
Fly |
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.158
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.157
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.153
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.152
|
|
|
|
phagolysosome assembly
|
GO:0001845 |
5 |
0.149
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.144
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.143
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.143
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.142
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.139
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.138
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.133
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.133
|
|
|
|
lysosome organization
|
GO:0007040 |
24 |
0.132
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.130
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.129
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.125
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.124
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.123
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.121
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.120
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.119
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.119
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.118
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.114
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.114
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.113
|
|
|
|
protein lipid complex assembly
|
GO:0065005 |
12 |
0.111
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.111
|
|
|
|
regulation of membrane tubulation
|
GO:1903525 |
2 |
0.109
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.108
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.108
|
|
|
|
regulation of short term neuronal synaptic plasticity
|
GO:0048172 |
1 |
0.106
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.106
|
|
|
|
memory
|
GO:0007613 |
3 |
0.104
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.104
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.102
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
7 |
0.098
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.097
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.095
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.094
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.094
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.094
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.093
|
Fly |
|
|
clathrin mediated endocytosis
|
GO:0072583 |
8 |
0.093
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.093
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.092
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.091
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.091
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.091
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.087
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.087
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.086
|
Mouse |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.085
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.084
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.083
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.083
|
|
|
|
lipid tube assembly
|
GO:0060988 |
2 |
0.081
|
|
|
|
negative regulation of actin nucleation
|
GO:0051126 |
3 |
0.080
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.080
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.080
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.077
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.076
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.076
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.075
|
Mouse |
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.075
|
|
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.072
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.071
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.070
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.069
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.068
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.068
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.068
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.067
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.067
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.067
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.066
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.066
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.065
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.065
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
1 |
0.064
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.064
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.064
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.063
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.063
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.063
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.063
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.063
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.062
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.062
|
Fly |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.062
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.062
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.061
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.061
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.061
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.060
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.060
|
Fly |
|
|
phagocytosis
|
GO:0006909 |
42 |
0.060
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.060
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.060
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.060
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.060
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.059
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.059
|
|
|
|
regulation of cell cell adhesion mediated by cadherin
|
GO:2000047 |
4 |
0.059
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.059
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.058
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.057
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.057
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.057
|
|
|
|
lytic vacuole organization
|
GO:0080171 |
24 |
0.057
|
|
|
|
growth
|
GO:0040007 |
202 |
0.056
|
Fly |
|
|
cilium assembly
|
GO:0042384 |
63 |
0.056
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.056
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.056
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.055
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.055
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.054
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.053
|
Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.053
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.052
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.052
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.052
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.052
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.052
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.051
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.051
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.051
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.051
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.051
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.050
|
|
|
|
vesicle transport along actin filament
|
GO:0030050 |
2 |
0.049
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.049
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.047
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.047
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.047
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.047
|
|
|
|
membrane invagination
|
GO:0010324 |
10 |
0.047
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.046
|
|
|
|
head development
|
GO:0060322 |
108 |
0.046
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.045
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.044
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.044
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.044
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.043
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.043
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.043
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.042
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.042
|
Fly |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.042
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.042
|
|
|
|
negative regulation of membrane tubulation
|
GO:1903526 |
2 |
0.042
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.042
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.042
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.041
|
Yeast |
|
|
positive regulation of astrocyte differentiation
|
GO:0048711 |
2 |
0.040
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.040
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.040
|
|
|
|
transferrin transport
|
GO:0033572 |
4 |
0.039
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.039
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.039
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.039
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.039
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.038
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.037
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.037
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.037
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.037
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.036
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.036
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.036
|
|
|
|
histone h2a s1 phosphorylation
|
GO:0043990 |
1 |
0.036
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.036
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.036
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.036
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.036
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.036
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.035
|
|
|
|
establishment or maintenance of neuroblast polarity
|
GO:0045196 |
1 |
0.035
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.035
|
Fly |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.034
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.034
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.034
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.034
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.034
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.034
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.034
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.034
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.033
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.033
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.033
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.033
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.033
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.033
|
Yeast |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.032
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.032
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.032
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.032
|
Human |
|
|
pinocytosis
|
GO:0006907 |
8 |
0.032
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.032
|
Yeast |
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.032
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.031
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.031
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.031
|
Fly |
|
|
barbed end actin filament capping
|
GO:0051016 |
3 |
0.031
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.031
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.031
|
|
|
|
positive regulation of synapse structural plasticity
|
GO:0051835 |
2 |
0.031
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.031
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.030
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.030
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.030
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.030
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
4 |
0.029
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
1 |
0.029
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.029
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.029
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.028
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.028
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.028
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.028
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.028
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.028
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.028
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.028
|
|
|
|
negative regulation of protein polymerization
|
GO:0032272 |
16 |
0.027
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.027
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.027
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.027
|
Yeast |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.027
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.027
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.027
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.027
|
Fly |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.027
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.027
|
|
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.027
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.026
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.026
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.026
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.026
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.026
|
|
|
|
learning
|
GO:0007612 |
11 |
0.025
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.025
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.025
|
|
|
|
fibroblast activation
|
GO:0072537 |
3 |
0.025
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.025
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.025
|
|
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.025
|
|
|
|
histone h3 s10 phosphorylation
|
GO:0043987 |
3 |
0.025
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.025
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.025
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.025
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.024
|
Mouse |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.024
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.024
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
17 |
0.024
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.024
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.024
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.024
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.024
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.024
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.024
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.023
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.023
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.023
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.023
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.023
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.023
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.023
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.023
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.023
|
Human |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.022
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.022
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.022
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.022
|
|
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.022
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.022
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.022
|
|
|
|
glial cell differentiation
|
GO:0010001 |
11 |
0.022
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.021
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.021
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.021
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.021
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.021
|
|
|
|
positive regulation of protein localization to plasma membrane
|
GO:1903078 |
20 |
0.021
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.021
|
|
|
|
toxin transport
|
GO:1901998 |
4 |
0.021
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
8 |
0.021
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.021
|
|
|
|
regulation of synaptic vesicle endocytosis
|
GO:1900242 |
1 |
0.020
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.020
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.020
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.020
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.020
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.020
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.020
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.020
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.020
|
Mouse |
|
|
response to virus
|
GO:0009615 |
126 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.020
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.020
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.020
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.020
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.020
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.020
|
Fly |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.019
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.019
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.019
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.019
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.019
|
|