IMP

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Homo sapiens

17 genes annotated in human

Multi-species View

negative regulation of protein depolymerization

GO:1901880

Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein depolymerization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of protein depolymerization" (in gray)

Name	Description	Probability	Func Analog Organism
AURKB	aurora kinase B	0.355
INCENP	inner centromere protein antigens 135/155kDa	0.317
BIRC5	baculoviral IAP repeat containing 5	0.284
CKS2	CDC28 protein kinase regulatory subunit 2	0.221
APC	adenomatous polyposis coli	0.213
ITGB4	integrin, beta 4	0.197
TPM1	tropomyosin 1 (alpha)	0.179	Worm
TRIM63	tripartite motif containing 63	0.174
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.167
KIF23	kinesin family member 23	0.150
RACGAP1	Rac GTPase activating protein 1	0.149
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.143
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.136
CDK1	cyclin-dependent kinase 1	0.132
MYPN	myopalladin	0.126
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.123
TPM2	tropomyosin 2 (beta)	0.122	Worm
CDCA8	cell division cycle associated 8	0.118
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.100
EXOC1	exocyst complex component 1	0.087
CORO1C	coronin, actin binding protein, 1C	0.083
GLIS2	GLIS family zinc finger 2	0.073
PDLIM7	PDZ and LIM domain 7 (enigma)	0.066
MYH9	myosin, heavy chain 9, non-muscle	0.061
TPM4	tropomyosin 4	0.059	Worm
ANKRD28	ankyrin repeat domain 28	0.059
CENPE	centromere protein E, 312kDa	0.056
CDK2	cyclin-dependent kinase 2	0.053
PSEN2	presenilin 2 (Alzheimer disease 4)	0.052
DST	dystonin	0.052	Fly
GRB2	growth factor receptor-bound protein 2	0.049
KIF1B	kinesin family member 1B	0.045
KIF20A	kinesin family member 20A	0.043
RIPK3	receptor-interacting serine-threonine kinase 3	0.042
GAS2L3	growth arrest-specific 2 like 3	0.039	Human
WASL	Wiskott-Aldrich syndrome-like	0.039
EXOC7	exocyst complex component 7	0.033
ATF7IP	activating transcription factor 7 interacting protein	0.032
IQGAP1	IQ motif containing GTPase activating protein 1	0.032
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.032
SPTBN1	spectrin, beta, non-erythrocytic 1	0.031
MARK2	MAP/microtubule affinity-regulating kinase 2	0.031
CCNA2	cyclin A2	0.030
DISC1	disrupted in schizophrenia 1	0.030
CENPJ	centromere protein J	0.030
ADRBK1	adrenergic, beta, receptor kinase 1	0.028
LBR	lamin B receptor	0.028
STIL	SCL/TAL1 interrupting locus	0.026
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.025
SVIL	supervillin	0.024
ITSN1	intersectin 1 (SH3 domain protein)	0.024
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.024
EXOC2	exocyst complex component 2	0.024
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.023
SOS1	son of sevenless homolog 1 (Drosophila)	0.023
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.022
SASS6	spindle assembly 6 homolog (C. elegans)	0.022
MACF1	microtubule-actin crosslinking factor 1	0.022	Fly
XPO1	exportin 1 (CRM1 homolog, yeast)	0.022
ERBB2IP	erbb2 interacting protein	0.021
ACTA1	actin, alpha 1, skeletal muscle	0.020
SUFU	suppressor of fused homolog (Drosophila)	0.020
TEX11	testis expressed 11	0.020
CTTN	cortactin	0.019
CCDC85A	coiled-coil domain containing 85A	0.019
KIF5B	kinesin family member 5B	0.018
ZRANB1	zinc finger, RAN-binding domain containing 1	0.018
C6orf211	chromosome 6 open reading frame 211	0.017
ACTN1	actinin, alpha 1	0.016
TUBGCP5	tubulin, gamma complex associated protein 5	0.016
JUP	junction plakoglobin	0.016
TNIK	TRAF2 and NCK interacting kinase	0.016
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.015
ZFP106	zinc finger protein 106 homolog (mouse)	0.014
OPTN	optineurin	0.014
GPSM2	G-protein signaling modulator 2	0.014
VCL	vinculin	0.014
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.013
MYL9	myosin, light chain 9, regulatory	0.013
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.013
GULP1	GULP, engulfment adaptor PTB domain containing 1	0.012
CYLD	cylindromatosis (turban tumor syndrome)	0.012
ARIH2	ariadne homolog 2 (Drosophila)	0.012
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.012
CNN1	calponin 1, basic, smooth muscle	0.012
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.012
CP110	CP110 protein	0.011
COL17A1	collagen, type XVII, alpha 1	0.011
PBK	PDZ binding kinase	0.011
KIF2C	kinesin family member 2C	0.011
ZYX	zyxin	0.011
PHLDB2	pleckstrin homology-like domain, family B, member 2	0.011
PRKCA	protein kinase C, alpha	0.011
CD164	CD164 molecule, sialomucin	0.011
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.011
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.011
SNX9	sorting nexin 9	0.011
AKAP11	A kinase (PRKA) anchor protein 11	0.010
WDR1	WD repeat domain 1	0.010	Yeast
KIF20B	kinesin family member 20B	0.010
CDKN3	cyclin-dependent kinase inhibitor 3	0.010
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.010
CLIC4	chloride intracellular channel 4	0.010