IMP
Process View
negative regulation of actin filament polymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of actin filament polymerization"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BAIAP2 | BAI1-associated protein 2 | 0.824 | ||
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.566 | ||
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.531 | ||
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.470 | Human | |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) | 0.364 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.362 | ||
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.355 | ||
| ABI1 | abl-interactor 1 | 0.280 | ||
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.279 | ||
| ACTG1 | actin, gamma 1 | 0.274 | ||
| ACTB | actin, beta | 0.258 | ||
| MYH9 | myosin, heavy chain 9, non-muscle | 0.243 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.212 | ||
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.171 | ||
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.163 | ||
| SQSTM1 | sequestosome 1 | 0.144 | ||
| RFX1 | regulatory factor X, 1 (influences HLA class II expression) | 0.131 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.128 | ||
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.119 | ||
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.104 | ||
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.102 | ||
| C3orf15 | chromosome 3 open reading frame 15 | 0.090 | ||
| MYPN | myopalladin | 0.081 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.079 | ||
| TTN | titin | 0.076 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.073 | ||
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.067 | ||
| OPTN | optineurin | 0.065 | ||
| CFL1 | cofilin 1 (non-muscle) | 0.058 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.051 | ||
| ATN1 | atrophin 1 | 0.048 | ||
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.044 | ||
| C14orf1 | chromosome 14 open reading frame 1 | 0.043 | ||
| MOBKL1B | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.042 | ||
| CD2AP | CD2-associated protein | 0.040 | ||
| WASF1 | WAS protein family, member 1 | 0.038 | ||
| VASP | vasodilator-stimulated phosphoprotein | 0.037 | ||
| C16orf53 | chromosome 16 open reading frame 53 | 0.033 | ||
| MYCBP | c-myc binding protein | 0.031 | ||
| CORO1C | coronin, actin binding protein, 1C | 0.030 | ||
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.030 | ||
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.027 | ||
| GOLGB1 | golgin B1 | 0.025 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.025 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.024 | ||
| TWF2 | twinfilin, actin-binding protein, homolog 2 (Drosophila) | 0.023 | ||
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.023 | ||
| MRPL20 | mitochondrial ribosomal protein L20 | 0.022 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.022 | ||
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.021 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.020 | ||
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.020 | ||
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.020 | ||
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.020 | ||
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.019 | ||
| CDCP1 | CUB domain containing protein 1 | 0.019 | ||
| WASF2 | WAS protein family, member 2 | 0.019 | ||
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.019 | ||
| NCKIPSD | NCK interacting protein with SH3 domain | 0.019 | ||
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.018 | ||
| CRMP1 | collapsin response mediator protein 1 | 0.017 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.017 | ||
| DNM2 | dynamin 2 | 0.017 | ||
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | 0.017 | ||
| KIF21A | kinesin family member 21A | 0.016 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.016 | ||
| RHOA | ras homolog gene family, member A | 0.016 | ||
| SNX2 | sorting nexin 2 | 0.016 | ||
| DLG5 | discs, large homolog 5 (Drosophila) | 0.016 | ||
| CAPNS1 | calpain, small subunit 1 | 0.015 | ||
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.014 | ||
| ZYX | zyxin | 0.014 | ||
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.014 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.014 | ||
| MYL12B | myosin, light chain 12B, regulatory | 0.014 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.013 | ||
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.013 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.013 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.013 | ||
| RXRA | retinoid X receptor, alpha | 0.012 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.012 | ||
| TAGLN2 | transgelin 2 | 0.012 | ||
| FLNA | filamin A, alpha | 0.012 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.012 | ||
| SNX9 | sorting nexin 9 | 0.011 | ||
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.011 | ||
| ADAM10 | ADAM metallopeptidase domain 10 | 0.011 | ||
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 0.011 | ||
| SVIL | supervillin | 0.011 | ||
| VCL | vinculin | 0.011 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.010 | ||
| ILK | integrin-linked kinase | 0.010 | ||
| HTT | huntingtin | 0.010 | ||
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.010 | Mouse Fly | |
| NBR1 | neighbor of BRCA1 gene 1 | 0.010 | ||
| RALB | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 0.010 | ||
| PRKCI | protein kinase C, iota | 0.010 |