Homo sapiens

11 known processes

PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

(Aliases: MGC116717,F6PK,PFRX,HL2K,MGC116715)

PFKFB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism carbohydrate metabolic process GO:0044723 193 0.390
Human Yeast Rat
monocarboxylic acid metabolic process GO:0032787 185 0.223
Human
cellular ketone metabolic process GO:0042180 80 0.221
carbohydrate metabolic process GO:0005975 207 0.217
Human Yeast Rat
oxidation reduction process GO:0055114 396 0.195
monosaccharide metabolic process GO:0005996 74 0.158
Yeast Rat
lipid metabolic process GO:0006629 381 0.134
cofactor metabolic process GO:0051186 87 0.131
chemical homeostasis GO:0048878 306 0.130
regulation of cellular ketone metabolic process GO:0010565 50 0.121
cation transport GO:0006812 331 0.108
response to oxygen containing compound GO:1901700 369 0.097
Rat
small molecule biosynthetic process GO:0044283 157 0.094
hexose metabolic process GO:0019318 55 0.081
Yeast Rat
pyruvate metabolic process GO:0006090 26 0.080
Human
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.079
Rat
cellular carbohydrate metabolic process GO:0044262 84 0.079
Human Rat
alkaloid catabolic process GO:0009822 3 0.079
carboxylic acid biosynthetic process GO:0046394 97 0.078
cellular amino acid metabolic process GO:0006520 116 0.077
cellular lipid metabolic process GO:0044255 303 0.075
metal ion transport GO:0030001 272 0.075
regulation of carbohydrate metabolic process GO:0006109 54 0.074
Rat
epoxygenase p450 pathway GO:0019373 3 0.072
response to nitrogen compound GO:1901698 184 0.068
Rat
response to organonitrogen compound GO:0010243 156 0.068
Rat
post embryonic development GO:0009791 2 0.067
transmembrane transport GO:0055085 399 0.067
regulation of cellular amine metabolic process GO:0033238 11 0.065
response to organic cyclic compound GO:0014070 204 0.064
Rat
single organism carbohydrate catabolic process GO:0044724 33 0.062
Human
inorganic ion transmembrane transport GO:0098660 231 0.062
amine metabolic process GO:0009308 44 0.061
phenylpropanoid metabolic process GO:0009698 3 0.060
coenzyme metabolic process GO:0006732 65 0.059
regulation of ion transport GO:0043269 189 0.057
muscle contraction GO:0006936 73 0.057
organonitrogen compound biosynthetic process GO:1901566 200 0.056
carbohydrate catabolic process GO:0016052 36 0.054
Human
organic acid biosynthetic process GO:0016053 97 0.053
positive regulation of transport GO:0051050 336 0.052
naphthalene containing compound metabolic process GO:0090420 1 0.052
regulation of cellular amino acid metabolic process GO:0006521 6 0.051
fatty acid metabolic process GO:0006631 115 0.051
glycerolipid metabolic process GO:0046486 107 0.050
generation of precursor metabolites and energy GO:0006091 68 0.050
Human
regulation of secretion GO:0051046 194 0.049
cellular homeostasis GO:0019725 196 0.049
alkaloid metabolic process GO:0009820 4 0.048
nitrogen compound transport GO:0071705 191 0.048
ion homeostasis GO:0050801 230 0.048
lipid biosynthetic process GO:0008610 177 0.048
system process GO:0003008 349 0.047
cellular amine metabolic process GO:0044106 41 0.047
multicellular organismal aging GO:0010259 3 0.045
organic hydroxy compound metabolic process GO:1901615 147 0.045
ion transmembrane transport GO:0034220 338 0.045
positive regulation of cellular amine metabolic process GO:0033240 7 0.043
cell cell signaling GO:0007267 155 0.042
female gamete generation GO:0007292 2 0.041
cytokine production GO:0001816 247 0.041
cellular response to endogenous stimulus GO:0071495 336 0.040
response to metal ion GO:0010038 84 0.040
locomotory behavior GO:0007626 1 0.040
secretion by cell GO:0032940 226 0.039
defense response GO:0006952 315 0.038
cellular chemical homeostasis GO:0055082 180 0.038
determination of adult lifespan GO:0008340 2 0.038
organic hydroxy compound transport GO:0015850 63 0.038
cation transmembrane transport GO:0098655 238 0.037
negative regulation of catalytic activity GO:0043086 335 0.037
regulation of protein kinase activity GO:0045859 289 0.037
organic anion transport GO:0015711 103 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
oogenesis GO:0048477 2 0.036
lipid catabolic process GO:0016042 84 0.036
negative regulation of phosphate metabolic process GO:0045936 267 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
positive regulation of catabolic process GO:0009896 310 0.034
response to hormone GO:0009725 175 0.034
Rat
lipid localization GO:0010876 106 0.034
cellular polysaccharide metabolic process GO:0044264 27 0.034
muscle system process GO:0003012 81 0.034
anion transport GO:0006820 161 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
response to abiotic stimulus GO:0009628 336 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.033
regeneration GO:0031099 4 0.033
Rat
isoquinoline alkaloid metabolic process GO:0033076 1 0.032
small molecule catabolic process GO:0044282 92 0.032
monovalent inorganic cation transport GO:0015672 128 0.032
memory GO:0007613 3 0.032
cellular response to nitrogen compound GO:1901699 144 0.031
coumarin metabolic process GO:0009804 2 0.031
drug catabolic process GO:0042737 10 0.031
cation homeostasis GO:0055080 189 0.030
regulation of metal ion transport GO:0010959 120 0.030
potassium ion transport GO:0006813 62 0.030
nucleotide catabolic process GO:0009166 408 0.030
response to lipid GO:0033993 206 0.030
Rat
regulation of response to external stimulus GO:0032101 222 0.030
secretion GO:0046903 254 0.029
g protein coupled receptor signaling pathway GO:0007186 207 0.029
purine containing compound catabolic process GO:0072523 411 0.029
immune response GO:0006955 307 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
protein catabolic process GO:0030163 325 0.028
carbohydrate transport GO:0008643 37 0.028
carbohydrate biosynthetic process GO:0016051 42 0.028
carboxylic acid catabolic process GO:0046395 71 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
mitochondrion organization GO:0007005 156 0.028
regulation of cytokine production GO:0001817 232 0.027
cellular response to oxygen containing compound GO:1901701 276 0.027
lipid transport GO:0006869 90 0.027
demethylation GO:0070988 37 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
protein localization to organelle GO:0033365 280 0.027
response to inorganic substance GO:0010035 127 0.027
glycogen metabolic process GO:0005977 22 0.027
growth GO:0040007 202 0.027
regulation of secretion by cell GO:1903530 177 0.026
divalent inorganic cation homeostasis GO:0072507 136 0.026
cellular organohalogen metabolic process GO:0090345 2 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
neuromuscular junction development GO:0007528 3 0.025
protein oligomerization GO:0051259 173 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
oxidative demethylation GO:0070989 11 0.025
striated muscle contraction GO:0006941 52 0.025
positive regulation of secretion GO:0051047 116 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
organic acid catabolic process GO:0016054 71 0.025
cellular polysaccharide biosynthetic process GO:0033692 21 0.025
peptide transport GO:0015833 74 0.025
negative regulation of transport GO:0051051 176 0.024
glycolytic process GO:0006096 17 0.024
Human
blood circulation GO:0008015 113 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
regulation of defense response GO:0031347 154 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
innate immune response GO:0045087 178 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
regulation of glucose metabolic process GO:0010906 28 0.023
Rat
metal ion homeostasis GO:0055065 169 0.023
cellular response to organonitrogen compound GO:0071417 124 0.023
quinone catabolic process GO:1901662 2 0.023
regulation of protein serine threonine kinase activity GO:0071900 179 0.023
protein processing GO:0016485 226 0.023
organophosphate catabolic process GO:0046434 430 0.023
glucan metabolic process GO:0044042 22 0.023
cellular glucan metabolic process GO:0006073 22 0.022
positive regulation of organelle organization GO:0010638 195 0.022
positive regulation of developmental process GO:0051094 314 0.022
naphthalene metabolic process GO:0018931 1 0.022
ras protein signal transduction GO:0007265 73 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
apoptotic mitochondrial changes GO:0008637 57 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
single organism membrane organization GO:0044802 268 0.022
energy reserve metabolic process GO:0006112 22 0.022
protein maturation GO:0051604 233 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
regulation of transferase activity GO:0051338 355 0.021
Rat
purine ribonucleotide catabolic process GO:0009154 404 0.021
monocarboxylic acid biosynthetic process GO:0072330 67 0.021
maintenance of location GO:0051235 112 0.021
nucleoside catabolic process GO:0009164 408 0.021
cellular lipid catabolic process GO:0044242 65 0.021
arachidonic acid metabolic process GO:0019369 14 0.021
response to extracellular stimulus GO:0009991 85 0.021
Rat
regulation of kinase activity GO:0043549 314 0.021
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
regulation of cellular component movement GO:0051270 334 0.021
regulation of hormone secretion GO:0046883 57 0.021
mitotic cell cycle GO:0000278 326 0.021
vesicle mediated transport GO:0016192 371 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
regulation of hormone levels GO:0010817 125 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
regulation of transmembrane transport GO:0034762 139 0.020
mapk cascade GO:0000165 288 0.020
response to nutrient levels GO:0031667 81 0.020
Rat
cellular response to hormone stimulus GO:0032870 125 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
nitrogen cycle metabolic process GO:0071941 3 0.020
polysaccharide metabolic process GO:0005976 33 0.020
membrane organization GO:0061024 292 0.020
amide transport GO:0042886 76 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
divalent inorganic cation transport GO:0072511 158 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.019
detection of stimulus GO:0051606 85 0.019
regulation of proteolysis GO:0030162 293 0.019
intracellular protein transport GO:0006886 270 0.019
cellular amino acid biosynthetic process GO:0008652 30 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
hormone transport GO:0009914 68 0.019
positive regulation of transferase activity GO:0051347 227 0.019
Rat
response to other organism GO:0051707 261 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
reactive oxygen species biosynthetic process GO:1903409 4 0.019
response to biotic stimulus GO:0009607 276 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
alpha amino acid metabolic process GO:1901605 72 0.019
menaquinone metabolic process GO:0009233 3 0.019
phylloquinone catabolic process GO:0042376 2 0.019
cytoplasmic transport GO:0016482 379 0.019
regulation of membrane potential GO:0042391 95 0.019
response to activity GO:0014823 0 0.018
single organism cellular localization GO:1902580 332 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
oocyte development GO:0048599 1 0.018
positive regulation of ion transport GO:0043270 87 0.018
cellular response to external stimulus GO:0071496 111 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
cellular protein catabolic process GO:0044257 261 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
negative regulation of protein modification process GO:0031400 200 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
regulation of protein transport GO:0051223 213 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
regulation of generation of precursor metabolites and energy GO:0043467 27 0.018
steroid metabolic process GO:0008202 94 0.018
monosaccharide transport GO:0015749 32 0.018
adult locomotory behavior GO:0008344 1 0.018
glucan biosynthetic process GO:0009250 16 0.018
cellular carbohydrate biosynthetic process GO:0034637 21 0.018
protein targeting GO:0006605 187 0.018
mitotic cell cycle process GO:1903047 286 0.018
calcium ion transport GO:0006816 147 0.018
carbohydrate homeostasis GO:0033500 31 0.018
regulation of cell cycle GO:0051726 393 0.017
synaptic transmission cholinergic GO:0007271 2 0.017
response to wounding GO:0009611 168 0.017
cellular response to organic cyclic compound GO:0071407 127 0.017
visual behavior GO:0007632 2 0.017
cell development GO:0048468 328 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
cellular ion homeostasis GO:0006873 168 0.017
regulation of mapk cascade GO:0043408 262 0.017
circulatory system process GO:0003013 113 0.017
vitamin k catabolic process GO:0042377 2 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
response to external biotic stimulus GO:0043207 261 0.017
response to drug GO:0042493 81 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
positive regulation of immune system process GO:0002684 283 0.016
nucleoside monophosphate metabolic process GO:0009123 191 0.016
oocyte differentiation GO:0009994 2 0.016
cellular cation homeostasis GO:0030003 163 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
divalent metal ion transport GO:0070838 152 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
Rat
atp metabolic process GO:0046034 176 0.016
regulation of glycogen metabolic process GO:0070873 15 0.016
regulation of ion transmembrane transporter activity GO:0032412 72 0.016
positive regulation of cytokine production GO:0001819 167 0.016
response to organophosphorus GO:0046683 41 0.016
Rat
apoptotic signaling pathway GO:0097190 268 0.016
long chain fatty acid metabolic process GO:0001676 30 0.016
regulation of muscle contraction GO:0006937 45 0.016
tissue regeneration GO:0042246 3 0.016
mating GO:0007618 1 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
regulation of system process GO:0044057 101 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
negative regulation of cellular organofluorine metabolic process GO:0090350 1 0.015
negative regulation of cellular organohalogen metabolic process GO:0090349 1 0.015
urea metabolic process GO:0019627 3 0.015
cell growth GO:0016049 160 0.015
response to cytokine GO:0034097 232 0.015
regulation of feeding behavior GO:0060259 3 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
regulation of cellular response to stress GO:0080135 244 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
segmentation GO:0035282 4 0.015
regulation of protein localization GO:0032880 296 0.015
protein homooligomerization GO:0051260 100 0.015
protein autophosphorylation GO:0046777 123 0.015
spermatid differentiation GO:0048515 4 0.015
rho protein signal transduction GO:0007266 26 0.015
negative regulation of protein processing GO:0010955 142 0.015
hormone secretion GO:0046879 65 0.015
positive regulation of synaptic transmission GO:0050806 4 0.015
associative learning GO:0008306 1 0.015
response to purine containing compound GO:0014074 40 0.015
Rat
cellular macromolecular complex assembly GO:0034622 324 0.015
cell morphogenesis GO:0000902 296 0.015
regulation of growth GO:0040008 165 0.015
protein ubiquitination GO:0016567 314 0.015
heart contraction GO:0060047 62 0.015
protein localization to nucleus GO:0034504 136 0.015
regulation of protein catabolic process GO:0042176 155 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
positive regulation of hydrolase activity GO:0051345 331 0.014
actin filament based process GO:0030029 224 0.014
peptide secretion GO:0002790 51 0.014
regulation of anatomical structure size GO:0090066 101 0.014
response to fungus GO:0009620 4 0.014
regulation of locomotion GO:0040012 329 0.014
response to mercury ion GO:0046689 4 0.014
atp catabolic process GO:0006200 157 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
regulation of peptide secretion GO:0002791 42 0.014
regulation of binding GO:0051098 111 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
regulation of response to wounding GO:1903034 101 0.014
covalent chromatin modification GO:0016569 254 0.014
positive regulation of organic acid transport GO:0032892 3 0.014
negative regulation of transferase activity GO:0051348 124 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
interspecies interaction between organisms GO:0044419 156 0.014
regulation of intracellular transport GO:0032386 195 0.014
hexose transport GO:0008645 30 0.014
regulation of immune response GO:0050776 201 0.014
regulation of cell cycle process GO:0010564 266 0.014
sulfur compound metabolic process GO:0006790 101 0.014
negative regulation of catabolic process GO:0009895 104 0.014
glycogen biosynthetic process GO:0005978 16 0.014
nuclear transport GO:0051169 179 0.014
cell cycle phase transition GO:0044770 173 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.014
spermatid development GO:0007286 4 0.014
activation of immune response GO:0002253 114 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
cell activation GO:0001775 213 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
icosanoid metabolic process GO:0006690 35 0.014
hyperosmotic response GO:0006972 4 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
regulation of transporter activity GO:0032409 82 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
carboxylic acid transport GO:0046942 63 0.013
cell division GO:0051301 168 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
regulation of peptide hormone secretion GO:0090276 41 0.013
cellular component morphogenesis GO:0032989 314 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
glucose homeostasis GO:0042593 31 0.013
positive regulation of kinase activity GO:0033674 204 0.013
Rat
glycoprotein biosynthetic process GO:0009101 91 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
phospholipid metabolic process GO:0006644 99 0.013
quorum sensing GO:0009372 1 0.013
blastoderm segmentation GO:0007350 2 0.013
circadian behavior GO:0048512 2 0.013
signal release GO:0023061 70 0.013
replicative cell aging GO:0001302 3 0.013
wound healing GO:0042060 115 0.013
linoleic acid metabolic process GO:0043651 4 0.013
regulation of cell differentiation GO:0045595 393 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
cardiovascular system development GO:0072358 262 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
organelle fission GO:0048285 149 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
response to xenobiotic stimulus GO:0009410 30 0.013
rhythmic behavior GO:0007622 2 0.013
negative regulation of icosanoid secretion GO:0032304 2 0.013
positive regulation of carbohydrate metabolic process GO:0045913 21 0.013
Rat
positive regulation of cell proliferation GO:0008284 301 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
pyruvate family amino acid catabolic process GO:0009080 3 0.013
regulation of cell migration GO:0030334 289 0.013
cardiac muscle contraction GO:0060048 34 0.013
somatic muscle development GO:0007525 1 0.013
negative regulation of organelle organization GO:0010639 126 0.013
phylloquinone metabolic process GO:0042374 2 0.013
actin filament based movement GO:0030048 17 0.013
positive regulation of protein transport GO:0051222 135 0.013
anterior posterior axis specification GO:0009948 2 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
nucleotide biosynthetic process GO:0009165 109 0.012
dephosphorylation GO:0016311 209 0.012
meiosis i GO:0007127 4 0.012
response to decreased oxygen levels GO:0036293 96 0.012
organic acid transport GO:0015849 65 0.012
biological adhesion GO:0022610 331 0.012
drug metabolic process GO:0017144 19 0.012
tripartite regional subdivision GO:0007351 2 0.012
nervous system development GO:0007399 293 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
nucleoside phosphate biosynthetic process GO:1901293 109 0.012
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.012
leukotriene catabolic process GO:0036100 2 0.012
negative regulation of proteolysis GO:0045861 132 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
micturition GO:0060073 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
glycoprotein metabolic process GO:0009100 110 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
startle response GO:0001964 3 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
calcium ion homeostasis GO:0055074 122 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
response to bacterium GO:0009617 144 0.012
reproductive process GO:0022414 106 0.012
immune effector process GO:0002252 159 0.012
polysaccharide biosynthetic process GO:0000271 27 0.012
endomembrane system organization GO:0010256 196 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
positive regulation of cell death GO:0010942 263 0.012
interspecies quorum sensing GO:0052097 1 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
multi organism cellular process GO:0044764 156 0.012
sleep GO:0030431 2 0.012
regulation of protein processing GO:0070613 150 0.012
multicellular organismal signaling GO:0035637 34 0.012
response to axon injury GO:0048678 1 0.012
negative regulation of kinase activity GO:0033673 106 0.012
glucose metabolic process GO:0006006 45 0.012
Yeast Rat
modification dependent protein catabolic process GO:0019941 209 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
visual learning GO:0008542 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
menaquinone catabolic process GO:0042361 2 0.011
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.011
regulation of gtpase activity GO:0043087 180 0.011
regulation of cellular component size GO:0032535 82 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
regulation of protein maturation GO:1903317 150 0.011
alcohol metabolic process GO:0006066 114 0.011
camp metabolic process GO:0046058 61 0.011
immune system development GO:0002520 195 0.011
response to radiation GO:0009314 151 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
alpha amino acid catabolic process GO:1901606 26 0.011
neurological system process GO:0050877 163 0.011
negative regulation of protein maturation GO:1903318 142 0.011
negative regulation of growth GO:0045926 97 0.011
compound eye development GO:0048749 1 0.011
myoblast fusion GO:0007520 1 0.011
chromatin organization GO:0006325 351 0.011
histone modification GO:0016570 251 0.011

PFKFB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.320
acquired metabolic disease DOID:0060158 58 0.101
musculoskeletal system disease DOID:17 223 0.048
muscular disease DOID:0080000 114 0.039
muscle tissue disease DOID:66 113 0.039
inherited metabolic disorder DOID:655 242 0.036
myopathy DOID:423 104 0.034
carbohydrate metabolism disease DOID:0050013 32 0.028
carbohydrate metabolic disorder DOID:2978 55 0.026
cardiovascular system disease DOID:1287 106 0.026
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.022
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
diabetes mellitus DOID:9351 31 0.021
glucose metabolism disease DOID:4194 32 0.021
heart disease DOID:114 68 0.019
sensory system disease DOID:0050155 203 0.016
type 2 diabetes mellitus DOID:9352 28 0.014
amino acid metabolic disorder DOID:9252 50 0.014
cardiomyopathy DOID:0050700 50 0.013
intrinsic cardiomyopathy DOID:0060036 50 0.013
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
neurodegenerative disease DOID:1289 102 0.013
disease of mental health DOID:150 70 0.012