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Homo sapiens

2 genes annotated in human

phylloquinone metabolic process

The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "phylloquinone metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "phylloquinone metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.998
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.974
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.949
RAB35	RAB35, member RAS oncogene family	0.917
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.887	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.784
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.559
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.518
KNG1	kininogen 1	0.430
HAL	histidine ammonia-lyase	0.401
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.390
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.387
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.336	Human
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.283
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.248
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.245
C8A	complement component 8, alpha polypeptide	0.239
ADH6	alcohol dehydrogenase 6 (class V)	0.214
G6PC	glucose-6-phosphatase, catalytic subunit	0.202
DAO	D-amino-acid oxidase	0.158
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.158
PLG	plasminogen	0.157
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.148
FABP1	fatty acid binding protein 1, liver	0.145
HPD	4-hydroxyphenylpyruvate dioxygenase	0.142
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.136
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.129
ARG1	arginase, liver	0.126
MAT1A	methionine adenosyltransferase I, alpha	0.121
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.113	Human
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.106
RDH16	retinol dehydrogenase 16 (all-trans)	0.103
F9	coagulation factor IX	0.094
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.094
OTC	ornithine carbamoyltransferase	0.089
DIO1	deiodinase, iodothyronine, type I	0.081
MASP2	mannan-binding lectin serine peptidase 2	0.076
BHMT	betaine--homocysteine S-methyltransferase	0.070
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.067
AADAC	arylacetamide deacetylase (esterase)	0.066
C8B	complement component 8, beta polypeptide	0.066
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.064
HNF4A	hepatocyte nuclear factor 4, alpha	0.062
GSTA3	glutathione S-transferase alpha 3	0.058
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.055
PKLR	pyruvate kinase, liver and RBC	0.054
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.054
C9	complement component 9	0.053
PAH	phenylalanine hydroxylase	0.053
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.052
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.051	Human
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.049
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.045
HGD	homogentisate 1,2-dioxygenase	0.044
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.043
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.042
FETUB	fetuin B	0.042
C6	complement component 6	0.041
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.041
AQP7	aquaporin 7	0.040
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.040
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.039
EPHX2	epoxide hydrolase 2, cytoplasmic	0.038
F13B	coagulation factor XIII, B polypeptide	0.037
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.036
APOF	apolipoprotein F	0.036
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.035
DEFB1	defensin, beta 1	0.034
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.033
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.032
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.031
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.031
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.031
CFHR4	complement factor H-related 4	0.031
FMO4	flavin containing monooxygenase 4	0.031
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.031
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.029
PIP	prolactin-induced protein	0.029
LIPC	lipase, hepatic	0.029
PRLR	prolactin receptor	0.027
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.027
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.026
CRP	C-reactive protein, pentraxin-related	0.026
ORM1	orosomucoid 1	0.026
APOC3	apolipoprotein C-III	0.025
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.025
CBR1	carbonyl reductase 1	0.025
C4BPA	complement component 4 binding protein, alpha	0.025
SPP2	secreted phosphoprotein 2, 24kDa	0.025
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.024
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.023
DPYS	dihydropyrimidinase	0.023
MTTP	microsomal triglyceride transfer protein	0.022
ORM2	orosomucoid 2	0.022
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.022
ALDOB	aldolase B, fructose-bisphosphate	0.021
FLG	filaggrin	0.021
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.021
SCGB2A1	secretoglobin, family 2A, member 1	0.020
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.020
F5	coagulation factor V (proaccelerin, labile factor)	0.020
HPX	hemopexin	0.020
CPB2	carboxypeptidase B2 (plasma)	0.020
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.020
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.019
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.019
CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1	0.019
PIPOX	pipecolic acid oxidase	0.019
LPA	lipoprotein, Lp(a)	0.019
GSTT1	glutathione S-transferase theta 1	0.019
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.019
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.019
CRISP2	cysteine-rich secretory protein 2	0.018
UNC93A	unc-93 homolog A (C. elegans)	0.018
AGXT	alanine-glyoxylate aminotransferase	0.018
CRISP3	cysteine-rich secretory protein 3	0.018
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.017
ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.017
KRT13	keratin 13	0.017
KHK	ketohexokinase (fructokinase)	0.017
IL22RA1	interleukin 22 receptor, alpha 1	0.017
C8G	complement component 8, gamma polypeptide	0.017
ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12	0.017
ANXA13	annexin A13	0.017
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.017
CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22	0.016	Human
GYS2	glycogen synthase 2 (liver)	0.016
ADRA1A	adrenergic, alpha-1A-, receptor	0.016
PRODH	proline dehydrogenase (oxidase) 1	0.016
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.016
C4BPB	complement component 4 binding protein, beta	0.016
ANGPTL3	angiopoietin-like 3	0.016
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.016
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.016
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.016
TMPRSS4	transmembrane protease, serine 4	0.016
F12	coagulation factor XII (Hageman factor)	0.015
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.015
CA5A	carbonic anhydrase VA, mitochondrial	0.015
CCL16	chemokine (C-C motif) ligand 16	0.015
LECT2	leukocyte cell-derived chemotaxin 2	0.014
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.014
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.014
CDHR5	cadherin-related family member 5	0.014
CES1	carboxylesterase 1	0.013
FMO5	flavin containing monooxygenase 5	0.013
IL1RL2	interleukin 1 receptor-like 2	0.013
GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.013
MOSC1	MOCO sulphurase C-terminal domain containing 1	0.013
ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.013
HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2	0.013
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.013
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.012
C9orf68	chromosome 9 open reading frame 68	0.012
UPB1	ureidopropionase, beta	0.012
TMEM40	transmembrane protein 40	0.012
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.012
S100A14	S100 calcium binding protein A14	0.012
KRT4	keratin 4	0.012
MGAM	maltase-glucoamylase (alpha-glucosidase)	0.012
MSMB	microseminoprotein, beta-	0.012
B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.012
PON1	paraoxonase 1	0.012
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.011
AGXT2	alanine--glyoxylate aminotransferase 2	0.011
FAM164C	family with sequence similarity 164, member C	0.011
C14orf105	chromosome 14 open reading frame 105	0.011
TTPA	tocopherol (alpha) transfer protein	0.011
ATP10B	ATPase, class V, type 10B	0.011
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.011
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.011
AGXT2L1	alanine-glyoxylate aminotransferase 2-like 1	0.011
CNGA1	cyclic nucleotide gated channel alpha 1	0.011
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.011
SCGB1D2	secretoglobin, family 1D, member 2	0.011
ADAM2	ADAM metallopeptidase domain 2	0.011
PON3	paraoxonase 3	0.011
CPS1	carbamoyl-phosphate synthase 1, mitochondrial	0.011
VTCN1	V-set domain containing T cell activation inhibitor 1	0.011
POF1B	premature ovarian failure, 1B	0.011
VIL1	villin 1	0.011
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	0.011
FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	0.011
CDA	cytidine deaminase	0.011
FCGBP	Fc fragment of IgG binding protein	0.010
SLC26A3	solute carrier family 26, member 3	0.010
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.010
ARIH2	ariadne homolog 2 (Drosophila)	0.010
LIN7A	lin-7 homolog A (C. elegans)	0.010
ANXA10	annexin A10	0.010