Process View
The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "modification dependent macromolecule catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| UBC | ubiquitin C | 1.000 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 1.000 | ||
| RNF11 | ring finger protein 11 | 1.000 | ||
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 1.000 | Yeast Worm | |
| VCP | valosin containing protein | 1.000 | ||
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 1.000 | Yeast | |
| SMAD2 | SMAD family member 2 | 1.000 | Human | |
| CUL3 | cullin 3 | 1.000 | ||
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 1.000 | Yeast | |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 1.000 | Yeast | |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 1.000 | ||
| TP53 | tumor protein p53 | 1.000 | ||
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 1.000 | Human Yeast | |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.999 | Yeast | |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.999 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.999 | ||
| UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.999 | Mouse | |
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.998 | Fly | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.998 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.998 | ||
| RB1 | retinoblastoma 1 | 0.998 | ||
| CUL1 | cullin 1 | 0.998 | ||
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.997 | Yeast Fly | |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.997 | Yeast | |
| BTRC | beta-transducin repeat containing | 0.997 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.996 | ||
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.995 | Yeast | |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.994 | Yeast | |
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.992 | ||
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.991 | Yeast | |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.991 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.991 | ||
| RNF111 | ring finger protein 111 | 0.991 | Mouse | |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.990 | ||
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.990 | ||
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.990 | Yeast | |
| XIAP | X-linked inhibitor of apoptosis | 0.990 | Human | |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.990 | Yeast | |
| UBQLN1 | ubiquilin 1 | 0.989 | Human | |
| RNF5 | ring finger protein 5 | 0.989 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.988 | ||
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.986 | ||
| PLK1 | polo-like kinase 1 | 0.986 | ||
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.982 | ||
| SMAD4 | SMAD family member 4 | 0.978 | Human | |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.978 | ||
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.975 | ||
| CUL2 | cullin 2 | 0.973 | Worm | |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.973 | Yeast | |
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.970 | ||
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.968 | Yeast | |
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.967 | Mouse | |
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.966 | ||
| BRCA1 | breast cancer 1, early onset | 0.966 | ||
| EXOSC3 | exosome component 3 | 0.965 | Yeast | |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.965 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.963 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.961 | Mouse Fly | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.961 | Human Mouse | |
| POMP | proteasome maturation protein | 0.959 | ||
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.955 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.953 | ||
| CCNB1 | cyclin B1 | 0.952 | ||
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.948 | ||
| ZNRF1 | zinc and ring finger 1 | 0.945 | Mouse | |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.942 | Yeast | |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.939 | Worm | |
| SMAD7 | SMAD family member 7 | 0.938 | ||
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.935 | ||
| TRIM39 | tripartite motif containing 39 | 0.930 | ||
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.928 | Yeast | |
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.926 | ||
| MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.925 | ||
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.921 | Yeast | |
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.914 | Human | |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.913 | Fly | |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.912 | Yeast | |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.909 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.902 | Yeast | |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.893 | ||
| SMAD5 | SMAD family member 5 | 0.890 | Human | |
| HDAC1 | histone deacetylase 1 | 0.889 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.884 | Mouse Fly | |
| CCNA2 | cyclin A2 | 0.883 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.883 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.876 | ||
| AMFR | autocrine motility factor receptor | 0.875 | ||
| YY1 | YY1 transcription factor | 0.866 | ||
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.866 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.864 | ||
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.859 | Yeast | |
| CDK2 | cyclin-dependent kinase 2 | 0.849 | ||
| TRIM43 | tripartite motif containing 43 | 0.834 | ||
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.832 | Zebrafish | |
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.832 | ||
| FAF2 | Fas associated factor family member 2 | 0.832 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.830 | Rat | |
| ANAPC4 | anaphase promoting complex subunit 4 | 0.830 | ||
| HSPA8 | heat shock 70kDa protein 8 | 0.829 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.820 | ||
| ANAPC7 | anaphase promoting complex subunit 7 | 0.817 | ||
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.817 | Yeast | |
| FBXO5 | F-box protein 5 | 0.809 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.808 | ||
| ACTB | actin, beta | 0.805 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.804 | ||
| EP300 | E1A binding protein p300 | 0.802 | ||
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.801 | Yeast Mouse | |
| RFWD2 | ring finger and WD repeat domain 2 | 0.785 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.783 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.774 | ||
| FBXW2 | F-box and WD repeat domain containing 2 | 0.774 | ||
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.772 | ||
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.771 | ||
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.771 | ||
| PJA2 | praja ring finger 2 | 0.769 | ||
| UBXN7 | UBX domain protein 7 | 0.766 | Yeast | |
| CUL5 | cullin 5 | 0.766 | ||
| TRIM21 | tripartite motif containing 21 | 0.762 | Human | |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.762 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.749 | Human | |
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.747 | Human Yeast | |
| ATXN3 | ataxin 3 | 0.746 | Mouse | |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.744 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.739 | ||
| RYBP | RING1 and YY1 binding protein | 0.735 | Fly | |
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.716 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.716 | Human | |
| EXOSC7 | exosome component 7 | 0.714 | Yeast | |
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.706 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.697 | ||
| AXIN1 | axin 1 | 0.695 | Mouse Rat | |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.691 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.688 | ||
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.681 | ||
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.677 | ||
| HDAC2 | histone deacetylase 2 | 0.671 | ||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.668 | ||
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.668 | Yeast Fly | |
| CUL4A | cullin 4A | 0.665 | Mouse | |
| UBXN1 | UBX domain protein 1 | 0.660 | ||
| ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.659 | Human Mouse Fly | |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.659 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.657 | Fly | |
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.652 | Worm Fly | |
| PPP5C | protein phosphatase 5, catalytic subunit | 0.651 | ||
| HSPA4 | heat shock 70kDa protein 4 | 0.648 | ||
| DIS3L | DIS3 mitotic control homolog (S. cerevisiae)-like | 0.648 | ||
| TADA3 | transcriptional adaptor 3 | 0.647 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.647 | Human | |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.642 | Mouse | |
| ARRB1 | arrestin, beta 1 | 0.642 | ||
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.624 | ||
| ANKRD17 | ankyrin repeat domain 17 | 0.622 | ||
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.622 | ||
| CSNK1E | casein kinase 1, epsilon | 0.622 | Mouse Fly | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.621 | ||
| RNF14 | ring finger protein 14 | 0.618 | ||
| STAG1 | stromal antigen 1 | 0.618 | ||
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.611 | ||
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.609 | ||
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | 0.607 | ||
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.606 | Yeast | |
| EXOSC2 | exosome component 2 | 0.603 | Yeast | |
| SMAD3 | SMAD family member 3 | 0.594 | Human | |
| UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | 0.585 | Yeast Mouse | |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.581 | ||
| PRKCA | protein kinase C, alpha | 0.577 | ||
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.566 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.564 | ||
| UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 0.558 | ||
| MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.553 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.552 | ||
| FBXO7 | F-box protein 7 | 0.550 | ||
| RNF20 | ring finger protein 20 | 0.549 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.548 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.542 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.538 | ||
| CREBBP | CREB binding protein | 0.537 | ||
| DAXX | death-domain associated protein | 0.533 | ||
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.532 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.531 | ||
| RNF7 | ring finger protein 7 | 0.528 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.525 | ||
| NCOA3 | nuclear receptor coactivator 3 | 0.522 | ||
| RNF2 | ring finger protein 2 | 0.516 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.514 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.513 | ||
| MIB1 | mindbomb homolog 1 (Drosophila) | 0.512 | ||
| SNX9 | sorting nexin 9 | 0.507 | ||
| AURKB | aurora kinase B | 0.504 | ||
| PSEN1 | presenilin 1 | 0.502 | Mouse | |
| RNF38 | ring finger protein 38 | 0.502 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.495 | ||
| UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.494 | Human Yeast Fly | |
| EXOSC9 | exosome component 9 | 0.492 | ||
| RNF144B | ring finger protein 144B | 0.482 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.477 | ||
| NCF2 | neutrophil cytosolic factor 2 | 0.468 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.465 | Yeast | |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.463 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.454 | ||
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.452 | ||
| MKRN1 | makorin ring finger protein 1 | 0.452 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.447 | Human | |
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.443 | ||
| MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.436 | ||
| HDAC6 | histone deacetylase 6 | 0.434 | Mouse | |
| BAG2 | BCL2-associated athanogene 2 | 0.432 | ||
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.430 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.427 | ||
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.427 | ||
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.426 | ||
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.423 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.423 | ||
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.422 | Fly | |
| SEC24B | SEC24 family, member B (S. cerevisiae) | 0.415 | ||
| SELS | selenoprotein S | 0.414 | ||
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.414 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.414 | Human | |
| PML | promyelocytic leukemia | 0.411 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.408 | ||
| ERBB2IP | erbb2 interacting protein | 0.408 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.403 | Human | |
| FOXM1 | forkhead box M1 | 0.402 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.398 | ||
| USP15 | ubiquitin specific peptidase 15 | 0.398 | Human | |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.395 | Human | |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.394 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.392 | Mouse | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.391 | ||
| ZNF263 | zinc finger protein 263 | 0.388 | ||
| DERL1 | Der1-like domain family, member 1 | 0.387 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.384 | ||
| TRIM5 | tripartite motif containing 5 | 0.379 | Human | |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.376 | ||
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.374 | ||
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.373 | Human | |
| RNF10 | ring finger protein 10 | 0.370 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.369 | ||
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.367 | Human | |
| RNF31 | ring finger protein 31 | 0.366 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.365 | Mouse | |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.365 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.364 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.363 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.360 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.355 | ||
| SMAD1 | SMAD family member 1 | 0.354 | Human | |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.347 | Yeast | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.345 | ||
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 | 0.340 | ||
| TRIM23 | tripartite motif containing 23 | 0.339 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.337 | Fly | |
| EAPP | E2F-associated phosphoprotein | 0.337 | ||
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.336 | Mouse | |
| EXOSC1 | exosome component 1 | 0.332 | Yeast | |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.330 | Human Yeast | |
| TRIM27 | tripartite motif containing 27 | 0.329 | Human | |
| ANXA7 | annexin A7 | 0.325 | ||
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.325 | ||
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.324 | Human | |
| CSNK1D | casein kinase 1, delta | 0.322 | Mouse Fly | |
| MYST1 | MYST histone acetyltransferase 1 | 0.322 | Human | |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.322 | Yeast | |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.322 | Human | |
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.319 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.319 | Human | |
| FBXW5 | F-box and WD repeat domain containing 5 | 0.318 | ||
| EPOR | erythropoietin receptor | 0.316 | ||
| CCNB2 | cyclin B2 | 0.312 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.311 | ||
| COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.310 | ||
| GFM1 | G elongation factor, mitochondrial 1 | 0.309 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.309 | ||
| MED21 | mediator complex subunit 21 | 0.307 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.307 | ||
| TRIM32 | tripartite motif containing 32 | 0.306 | ||
| ATXN1 | ataxin 1 | 0.306 | ||
| MED15 | mediator complex subunit 15 | 0.306 | ||
| CHMP4B | chromatin modifying protein 4B | 0.304 | ||
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.302 | Yeast | |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.300 | ||
| HSPA1B | heat shock 70kDa protein 1B | 0.299 | ||
| FLNB | filamin B, beta | 0.299 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.298 | ||
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.296 | Mouse | |
| DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.294 | Human | |
| SSR1 | signal sequence receptor, alpha | 0.290 | ||
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.287 | ||
| INO80 | INO80 homolog (S. cerevisiae) | 0.286 | ||
| RNF168 | ring finger protein 168 | 0.285 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.284 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.284 | ||
| EXOSC10 | exosome component 10 | 0.280 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.276 | ||
| FBXO33 | F-box protein 33 | 0.275 | ||
| AR | androgen receptor | 0.275 | ||
| ZNF496 | zinc finger protein 496 | 0.275 | ||
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.274 | ||
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.272 | ||
| TBK1 | TANK-binding kinase 1 | 0.266 | ||
| FBXO3 | F-box protein 3 | 0.264 | ||
| KCTD10 | potassium channel tetramerisation domain containing 10 | 0.262 | Human | |
| UBE2K | ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) | 0.261 | Yeast Mouse | |
| DTX3L | deltex 3-like (Drosophila) | 0.261 | ||
| QKI | quaking homolog, KH domain RNA binding (mouse) | 0.260 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.257 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.257 | ||
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.255 | ||
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.252 | ||
| NBN | nibrin | 0.251 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.247 | ||
| RNF185 | ring finger protein 185 | 0.247 | Human | |
| DIS3 | DIS3 mitotic control homolog (S. cerevisiae) | 0.247 | ||
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.246 | ||
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.246 | ||
| UBXN6 | UBX domain protein 6 | 0.244 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.243 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.242 | ||
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.240 | ||
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.237 | ||
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.231 | ||
| PCM1 | pericentriolar material 1 | 0.229 | ||
| USP38 | ubiquitin specific peptidase 38 | 0.227 | ||
| SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.227 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.227 | ||
| MBD3 | methyl-CpG binding domain protein 3 | 0.226 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.226 | ||
| ANKRD13A | ankyrin repeat domain 13A | 0.224 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.223 | ||
| MTA2 | metastasis associated 1 family, member 2 | 0.223 | Human | |
| CUL4B | cullin 4B | 0.221 | ||
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.220 | ||
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.219 | ||
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.219 | ||
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.217 | Human | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.217 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.216 | Mouse | |
| RANBP9 | RAN binding protein 9 | 0.216 | ||
| CCDC101 | coiled-coil domain containing 101 | 0.215 | ||
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.212 | ||
| CDYL | chromodomain protein, Y-like | 0.209 | ||
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.209 | ||
| VPRBP | Vpr (HIV-1) binding protein | 0.208 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.207 | ||
| RANBP2 | RAN binding protein 2 | 0.206 | ||
| SIRT2 | sirtuin 2 | 0.206 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.204 | ||
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.202 | Yeast | |
| SNIP1 | Smad nuclear interacting protein 1 | 0.202 | ||
| NCAM1 | neural cell adhesion molecule 1 | 0.201 | ||
| RNF8 | ring finger protein 8 | 0.201 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.199 | ||
| INCENP | inner centromere protein antigens 135/155kDa | 0.198 | ||
| SIRT1 | sirtuin 1 | 0.198 | ||
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.198 | ||
| CHFR | checkpoint with forkhead and ring finger domains | 0.196 | ||
| WDR26 | WD repeat domain 26 | 0.195 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.195 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.195 | ||
| RNF4 | ring finger protein 4 | 0.194 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.193 | Mouse | |
| CLOCK | clock homolog (mouse) | 0.191 | Mouse | |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.191 | ||
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.191 | ||
| APC | adenomatous polyposis coli | 0.190 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.190 | ||
| RNF126 | ring finger protein 126 | 0.189 | ||
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.189 | ||
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.189 | ||
| PCBP2 | poly(rC) binding protein 2 | 0.186 | ||
| UBE3A | ubiquitin protein ligase E3A | 0.181 | Mouse Fly | |
| AXIN2 | axin 2 | 0.181 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.180 | ||
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.179 | Yeast | |
| NCK2 | NCK adaptor protein 2 | 0.179 | ||
| UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.178 | ||
| BMI1 | BMI1 polycomb ring finger oncogene | 0.178 | ||
| TPBG | trophoblast glycoprotein | 0.178 | ||
| TRAF4 | TNF receptor-associated factor 4 | 0.178 | ||
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.178 | Mouse | |
| MYO1C | myosin IC | 0.177 | ||
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.177 | ||
| RC3H2 | ring finger and CCCH-type domains 2 | 0.176 | ||
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.176 | ||
| USP2 | ubiquitin specific peptidase 2 | 0.175 | Yeast | |
| RBL1 | retinoblastoma-like 1 (p107) | 0.174 | Human | |
| CCND1 | cyclin D1 | 0.173 | ||
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.173 | Mouse | |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.171 | ||
| RNF114 | ring finger protein 114 | 0.170 | ||
| TRIM25 | tripartite motif containing 25 | 0.167 | ||
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.166 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.166 | ||
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.166 | ||
| C11orf58 | chromosome 11 open reading frame 58 | 0.166 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.166 | Mouse | |
| ORC1 | origin recognition complex, subunit 1 | 0.166 | ||
| LPXN | leupaxin | 0.166 | Human | |
| BABAM1 | BRISC and BRCA1 A complex member 1 | 0.165 | ||
| FEM1B | fem-1 homolog b (C. elegans) | 0.163 | ||
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | 0.162 | ||
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.161 | ||
| EXOSC4 | exosome component 4 | 0.160 | Yeast | |
| TFDP1 | transcription factor Dp-1 | 0.160 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.157 | ||
| KDM1A | lysine (K)-specific demethylase 1A | 0.156 | ||
| DCTN4 | dynactin 4 (p62) | 0.156 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.155 | ||
| CDKN2AIP | CDKN2A interacting protein | 0.155 | ||
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.155 | ||
| TLK1 | tousled-like kinase 1 | 0.154 | Human | |
| AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | 0.154 | ||
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.154 | ||
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.154 | ||
| NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.153 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.153 | ||
| ATF3 | activating transcription factor 3 | 0.153 | ||
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.153 | ||
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.153 | Human | |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.152 | ||
| SFN | stratifin | 0.152 | ||
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.151 | ||
| ATM | ataxia telangiectasia mutated | 0.151 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.150 | ||
| ING2 | inhibitor of growth family, member 2 | 0.149 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.149 | Rat | |
| HERC2 | hect domain and RLD 2 | 0.149 | ||
| RPN1 | ribophorin I | 0.149 | ||
| UBXN2A | UBX domain protein 2A | 0.149 | ||
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.148 | ||
| TMEM173 | transmembrane protein 173 | 0.148 | ||
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.147 | Human Yeast Mouse | |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.147 | ||
| TRIM37 | tripartite motif containing 37 | 0.147 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.146 | Human | |
| MLL2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.145 | ||
| ATF5 | activating transcription factor 5 | 0.145 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.145 | ||
| C11orf2 | chromosome 11 open reading frame 2 | 0.144 | ||
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.143 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.143 | ||
| TSG101 | tumor susceptibility gene 101 | 0.143 | ||
| RNF181 | ring finger protein 181 | 0.142 | ||
| PRKCD | protein kinase C, delta | 0.142 | ||
| ZYG11B | zyg-11 homolog B (C. elegans) | 0.142 | ||
| KIAA0232 | KIAA0232 | 0.142 | ||
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 0.141 | ||
| NOMO1 | NODAL modulator 1 | 0.140 | ||
| KPNB1 | karyopherin (importin) beta 1 | 0.140 | ||
| IER3 | immediate early response 3 | 0.139 | ||
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.139 | ||
| TGS1 | trimethylguanosine synthase 1 | 0.139 | ||
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.139 | ||
| BTBD10 | BTB (POZ) domain containing 10 | 0.138 | ||
| TBP | TATA box binding protein | 0.137 | ||
| SGOL2 | shugoshin-like 2 (S. pombe) | 0.135 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.135 | ||
| RBBP7 | retinoblastoma binding protein 7 | 0.134 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.133 | ||
| NUDCD3 | NudC domain containing 3 | 0.133 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.133 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.133 | ||
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.133 | ||
| BFAR | bifunctional apoptosis regulator | 0.133 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.132 | ||
| ILK | integrin-linked kinase | 0.131 | ||
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.131 | ||
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.131 | ||
| GATAD2B | GATA zinc finger domain containing 2B | 0.130 | ||
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.130 | ||
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.130 | ||
| TRIM33 | tripartite motif containing 33 | 0.130 | ||
| TRIM41 | tripartite motif containing 41 | 0.129 | Human | |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.129 | Mouse | |
| COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.128 | ||
| DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.128 | ||
| BAG1 | BCL2-associated athanogene | 0.128 | ||
| CDC37L1 | cell division cycle 37 homolog (S. cerevisiae)-like 1 | 0.127 | ||
| RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.127 | ||
| RNF130 | ring finger protein 130 | 0.127 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.127 | ||
| FBXO28 | F-box protein 28 | 0.126 | ||
| ZNF207 | zinc finger protein 207 | 0.126 | ||
| KARS | lysyl-tRNA synthetase | 0.125 | ||
| SAE1 | SUMO1 activating enzyme subunit 1 | 0.125 | ||
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.124 | Yeast | |
| SKIL | SKI-like oncogene | 0.124 | ||
| STIP1 | stress-induced-phosphoprotein 1 | 0.123 | ||
| NEURL4 | neuralized homolog 4 (Drosophila) | 0.123 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.123 | ||
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.123 | ||
| MTA1 | metastasis associated 1 | 0.122 | ||
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.122 | ||
| UBD | ubiquitin D | 0.122 | ||
| ANKRD13C | ankyrin repeat domain 13C | 0.122 | ||
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.121 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.120 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.119 | ||
| ASF1A | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.119 | ||
| ANAPC10 | anaphase promoting complex subunit 10 | 0.118 | Yeast | |
| ZMYM2 | zinc finger, MYM-type 2 | 0.118 | ||
| CCDC99 | coiled-coil domain containing 99 | 0.117 | ||
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.117 | Human | |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.117 | ||
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.117 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.117 | ||
| CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.117 | ||
| RIOK2 | RIO kinase 2 (yeast) | 0.117 | ||
| RHOB | ras homolog gene family, member B | 0.117 | ||
| PRKCB | protein kinase C, beta | 0.116 | ||
| KEAP1 | kelch-like ECH-associated protein 1 | 0.116 | Human | |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 0.116 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.116 | ||
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.116 | ||
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.116 | Human | |
| RFWD3 | ring finger and WD repeat domain 3 | 0.115 | ||
| MTMR6 | myotubularin related protein 6 | 0.115 | ||
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.115 | ||
| PAPOLA | poly(A) polymerase alpha | 0.115 | ||
| BTBD2 | BTB (POZ) domain containing 2 | 0.113 | ||
| RANGAP1 | Ran GTPase activating protein 1 | 0.113 | ||
| SIAH2 | seven in absentia homolog 2 (Drosophila) | 0.113 | Human | |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.112 | ||
| TOR1AIP2 | torsin A interacting protein 2 | 0.112 | ||
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.112 | ||
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.112 | ||
| DERL2 | Der1-like domain family, member 2 | 0.112 | ||
| GORAB | golgin, RAB6-interacting | 0.111 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.111 | ||
| HSPA1A | heat shock 70kDa protein 1A | 0.111 | ||
| ATMIN | ATM interactor | 0.111 | ||
| LAP3 | leucine aminopeptidase 3 | 0.111 | ||
| KSR1 | kinase suppressor of ras 1 | 0.110 | Human | |
| RBBP5 | retinoblastoma binding protein 5 | 0.109 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.109 | ||
| DAPK1 | death-associated protein kinase 1 | 0.109 | ||
| PHF20 | PHD finger protein 20 | 0.109 | ||
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.109 | ||
| RNF103 | ring finger protein 103 | 0.108 | ||
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.108 | ||
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.108 | ||
| KIF5B | kinesin family member 5B | 0.108 | ||
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.107 | ||
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.107 | ||
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | 0.106 | ||
| PHF21A | PHD finger protein 21A | 0.106 | ||
| BTBD1 | BTB (POZ) domain containing 1 | 0.106 | ||
| RAD18 | RAD18 homolog (S. cerevisiae) | 0.106 | ||
| OTUD5 | OTU domain containing 5 | 0.105 | ||
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.105 | ||
| LIN28B | lin-28 homolog B (C. elegans) | 0.105 | ||
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.105 | ||
| MAPK9 | mitogen-activated protein kinase 9 | 0.105 | ||
| COIL | coilin | 0.105 | ||
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.104 | ||
| STMN1 | stathmin 1 | 0.104 | ||
| CCND3 | cyclin D3 | 0.103 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.102 | ||
| VTA1 | Vps20-associated 1 homolog (S. cerevisiae) | 0.102 | ||
| SLC38A2 | solute carrier family 38, member 2 | 0.102 | ||
| HDAC11 | histone deacetylase 11 | 0.102 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.102 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.102 | Fly | |
| E2F1 | E2F transcription factor 1 | 0.101 | ||
| UBB | ubiquitin B | 0.101 | ||
| ATF7IP | activating transcription factor 7 interacting protein | 0.100 | ||
| UBQLN4 | ubiquilin 4 | 0.100 | ||
| CDK17 | cyclin-dependent kinase 17 | 0.100 | ||
| DEPDC1 | DEP domain containing 1 | 0.099 | ||
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.098 | ||
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.098 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.097 | ||
| USO1 | USO1 vesicle docking protein homolog (yeast) | 0.097 | ||
| JUN | jun proto-oncogene | 0.097 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.096 | ||
| FBXW9 | F-box and WD repeat domain containing 9 | 0.096 | ||
| KLHL2 | kelch-like 2, Mayven (Drosophila) | 0.096 | Human | |
| TRIM34 | tripartite motif containing 34 | 0.096 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.096 | ||
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.095 | ||
| PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.095 | ||
| NPEPPS | aminopeptidase puromycin sensitive | 0.095 | ||
| THOC3 | THO complex 3 | 0.095 | ||
| USP25 | ubiquitin specific peptidase 25 | 0.095 | ||
| ARRB2 | arrestin, beta 2 | 0.095 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.095 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.094 | ||
| PAWR | PRKC, apoptosis, WT1, regulator | 0.094 | ||
| TRIM63 | tripartite motif containing 63 | 0.094 | Human Mouse | |
| VCL | vinculin | 0.094 | ||
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.093 | ||
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.093 | ||
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.093 | ||
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.093 | ||
| PXN | paxillin | 0.093 | Human | |
| CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.093 | ||
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.093 | ||
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.093 | Fly | |
| BCL2L1 | BCL2-like 1 | 0.093 | ||
| GLI1 | GLI family zinc finger 1 | 0.092 | ||
| SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.091 | ||
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 | 0.091 | ||
| MID1 | midline 1 (Opitz/BBB syndrome) | 0.090 | ||
| CBX5 | chromobox homolog 5 | 0.090 | ||
| WDR13 | WD repeat domain 13 | 0.090 | ||
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.090 | ||
| UNC45A | unc-45 homolog A (C. elegans) | 0.090 | ||
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.090 | ||
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.089 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.089 | ||
| DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.089 | ||
| RING1 | ring finger protein 1 | 0.089 | ||
| RAB21 | RAB21, member RAS oncogene family | 0.089 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.089 | ||
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.089 | ||
| TROVE2 | TROVE domain family, member 2 | 0.088 | ||
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.088 | ||
| CTR9 | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.088 | ||
| SOCS5 | suppressor of cytokine signaling 5 | 0.087 | ||
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.087 | ||
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.087 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.087 | ||
| MAK | male germ cell-associated kinase | 0.087 | ||
| OSTC | oligosaccharyltransferase complex subunit | 0.087 | ||
| NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.086 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.086 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.085 | ||
| FBXO30 | F-box protein 30 | 0.085 | ||
| BIRC8 | baculoviral IAP repeat containing 8 | 0.085 | Human | |
| ARMC7 | armadillo repeat containing 7 | 0.085 | ||
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.085 | ||
| RLIM | ring finger protein, LIM domain interacting | 0.085 | Mouse | |
| AUP1 | ancient ubiquitous protein 1 | 0.085 | ||
| SETX | senataxin | 0.085 | ||
| TRIM9 | tripartite motif containing 9 | 0.085 | ||
| TXNL1 | thioredoxin-like 1 | 0.084 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.084 | ||
| KDM4A | lysine (K)-specific demethylase 4A | 0.084 | ||
| SRP54 | signal recognition particle 54kDa | 0.084 | ||
| TUBB2C | tubulin, beta 2C | 0.083 | ||
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.083 | ||
| FBXO4 | F-box protein 4 | 0.083 | ||
| CCDC50 | coiled-coil domain containing 50 | 0.083 | ||
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.083 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.083 | ||
| POLH | polymerase (DNA directed), eta | 0.083 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.083 | ||
| HIST2H2AC | histone cluster 2, H2ac | 0.083 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.083 | ||
| DBP | D site of albumin promoter (albumin D-box) binding protein | 0.083 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.083 | ||
| UBOX5 | U-box domain containing 5 | 0.082 | ||
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.082 | ||
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.082 | ||
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.082 | ||
| CD44 | CD44 molecule (Indian blood group) | 0.082 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.082 | ||
| FAM175B | family with sequence similarity 175, member B | 0.082 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.081 | ||
| ANKRD28 | ankyrin repeat domain 28 | 0.081 | ||
| XBP1 | X-box binding protein 1 | 0.081 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.081 | ||
| KALRN | kalirin, RhoGEF kinase | 0.081 | ||
| MEX3B | mex-3 homolog B (C. elegans) | 0.081 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.081 | ||
| SNX18 | sorting nexin 18 | 0.081 | ||
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.081 | ||
| SP100 | SP100 nuclear antigen | 0.080 | ||
| VBP1 | von Hippel-Lindau binding protein 1 | 0.080 | ||
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.080 | ||
| TRIB3 | tribbles homolog 3 (Drosophila) | 0.080 | Fly | |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.080 | ||
| MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.080 | ||
| KIF2C | kinesin family member 2C | 0.080 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.080 | ||
| PHF20L1 | PHD finger protein 20-like 1 | 0.079 | ||
| EIF4E | eukaryotic translation initiation factor 4E | 0.079 | ||
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | 0.079 | ||
| RBM4 | RNA binding motif protein 4 | 0.079 | ||
| RNF40 | ring finger protein 40 | 0.079 | Human Rat | |
| MTDH | metadherin | 0.078 | ||
| NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.078 | ||
| RIF1 | RAP1 interacting factor homolog (yeast) | 0.078 | ||
| SLC25A36 | solute carrier family 25, member 36 | 0.077 | ||
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.077 | ||
| KLHL13 | kelch-like 13 (Drosophila) | 0.077 | Human | |
| RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.077 | ||
| MYD88 | myeloid differentiation primary response gene (88) | 0.077 | ||
| RNF26 | ring finger protein 26 | 0.077 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.077 | ||
| FUNDC2 | FUN14 domain containing 2 | 0.076 | ||
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.076 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.076 | Human | |
| FEN1 | flap structure-specific endonuclease 1 | 0.075 | ||
| DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.075 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.075 | ||
| MRPL10 | mitochondrial ribosomal protein L10 | 0.075 | ||
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.075 | ||
| RCOR1 | REST corepressor 1 | 0.075 | ||
| C12orf44 | chromosome 12 open reading frame 44 | 0.075 | ||
| MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.075 | ||
| MYO6 | myosin VI | 0.074 | ||
| LNX1 | ligand of numb-protein X 1 | 0.074 | Mouse | |
| UBA7 | ubiquitin-like modifier activating enzyme 7 | 0.074 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.074 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.074 | ||
| SQSTM1 | sequestosome 1 | 0.074 | ||
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.074 | ||
| DTX3 | deltex homolog 3 (Drosophila) | 0.073 | ||
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.073 | ||
| STAU1 | staufen, RNA binding protein, homolog 1 (Drosophila) | 0.073 | ||
| SNX16 | sorting nexin 16 | 0.073 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.073 | ||
| TRIP13 | thyroid hormone receptor interactor 13 | 0.073 | ||
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.073 | ||
| TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.073 | ||
| KIAA1524 | KIAA1524 | 0.073 | ||
| GRSF1 | G-rich RNA sequence binding factor 1 | 0.073 | ||
| SHPRH | SNF2 histone linker PHD RING helicase | 0.073 | ||
| DHPS | deoxyhypusine synthase | 0.072 | ||
| WDR45 | WD repeat domain 45 | 0.072 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.072 | ||
| COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.072 | Worm | |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 0.072 | ||
| TCP1 | t-complex 1 | 0.072 | ||
| RAB18 | RAB18, member RAS oncogene family | 0.072 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.072 | ||
| MBD1 | methyl-CpG binding domain protein 1 | 0.071 | ||
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 0.071 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.071 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.071 | ||
| NCSTN | nicastrin | 0.071 | ||
| MPHOSPH6 | M-phase phosphoprotein 6 | 0.071 | ||
| S100A4 | S100 calcium binding protein A4 | 0.070 | ||
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.070 | ||
| IRF9 | interferon regulatory factor 9 | 0.070 | ||
| PINK1 | PTEN induced putative kinase 1 | 0.070 | Fly | |
| WAC | WW domain containing adaptor with coiled-coil | 0.070 | ||
| FKBP3 | FK506 binding protein 3, 25kDa | 0.070 | ||
| HSF1 | heat shock transcription factor 1 | 0.070 | ||
| POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.070 | ||
| KCTD3 | potassium channel tetramerisation domain containing 3 | 0.070 | ||
| OTUD4 | OTU domain containing 4 | 0.069 | ||
| RIC8A | resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | 0.069 | ||
| DPP8 | dipeptidyl-peptidase 8 | 0.069 | ||
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.069 | ||
| SOD1 | superoxide dismutase 1, soluble | 0.069 | ||
| MATK | megakaryocyte-associated tyrosine kinase | 0.069 | Human |