Homo sapiens

83 known processes

SHC1

SHC (Src homology 2 domain containing) transforming protein 1

(Aliases: FLJ26504,SHC,SHCA)

SHC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
enzyme linked receptor protein signaling pathway GO:0007167 303 1.000
Mouse Rat Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 1.000
Mouse Rat Fly
regulation of kinase activity GO:0043549 314 1.000
positive regulation of map kinase activity GO:0043406 80 1.000
ras protein signal transduction GO:0007265 73 1.000
regulation of cellular amino acid metabolic process GO:0006521 6 1.000
regulation of cell migration GO:0030334 289 1.000
positive regulation of kinase activity GO:0033674 204 1.000
actin filament organization GO:0007015 128 1.000
regulation of map kinase activity GO:0043405 108 1.000
biological adhesion GO:0022610 331 1.000
Mouse
cellular response to endogenous stimulus GO:0071495 336 1.000
Rat
associative learning GO:0008306 1 1.000
positive regulation of transport GO:0051050 336 1.000
actin filament based process GO:0030029 224 1.000
Mouse Rat
cell activation GO:0001775 213 0.999
regulation of immune response GO:0050776 201 0.999
actin cytoskeleton organization GO:0030036 207 0.999
Mouse Rat
positive regulation of lipid metabolic process GO:0045834 50 0.999
leukocyte activation GO:0045321 164 0.999
positive regulation of cell proliferation GO:0008284 301 0.999
Rat
cellular response to nitrogen compound GO:1901699 144 0.999
Rat
regulation of locomotion GO:0040012 329 0.999
vesicle mediated transport GO:0016192 371 0.999
positive regulation of developmental process GO:0051094 314 0.999
regulation of cellular amine metabolic process GO:0033238 11 0.999
regulation of transferase activity GO:0051338 355 0.999
cell adhesion GO:0007155 325 0.999
Mouse
amine metabolic process GO:0009308 44 0.998
peptidyl tyrosine modification GO:0018212 170 0.998
phosphatidylinositol mediated signaling GO:0048015 55 0.997
negative regulation of cell death GO:0060548 345 0.997
cellular amine metabolic process GO:0044106 41 0.997
regulation of mapk cascade GO:0043408 262 0.997
response to organonitrogen compound GO:0010243 156 0.997
Rat
phospholipid metabolic process GO:0006644 99 0.997
cellular lipid metabolic process GO:0044255 303 0.997
regulation of protein serine threonine kinase activity GO:0071900 179 0.997
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.996
positive regulation of immune system process GO:0002684 283 0.996
positive regulation of cellular component organization GO:0051130 376 0.996
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.995
regulation of cell adhesion GO:0030155 166 0.995
positive regulation of protein kinase activity GO:0045860 190 0.995
cellular amino acid metabolic process GO:0006520 116 0.995
regulation of cellular component movement GO:0051270 334 0.994
positive regulation of cellular component movement GO:0051272 181 0.994
regulation of cell motility GO:2000145 299 0.993
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.993
positive regulation of mapk cascade GO:0043410 190 0.993
regulation of cellular ketone metabolic process GO:0010565 50 0.992
positive regulation of phosphorylation GO:0042327 394 0.992
peptidyl tyrosine phosphorylation GO:0018108 170 0.992
positive regulation of cell migration GO:0030335 172 0.991
cell development GO:0048468 328 0.991
Rat
protein autophosphorylation GO:0046777 123 0.991
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 12 0.990
inositol lipid mediated signaling GO:0048017 55 0.988
positive regulation of locomotion GO:0040017 186 0.988
regulation of neuron differentiation GO:0045664 70 0.988
single organismal cell cell adhesion GO:0016337 148 0.988
Mouse
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.987
regulation of secretion by cell GO:1903530 177 0.987
positive regulation of protein phosphorylation GO:0001934 313 0.986
immune response activating signal transduction GO:0002757 90 0.985
positive regulation of immune response GO:0050778 159 0.985
regulation of intracellular transport GO:0032386 195 0.984
positive regulation of transferase activity GO:0051347 227 0.984
secretion GO:0046903 254 0.984
lymphocyte activation GO:0046649 133 0.983
regulation of lipid kinase activity GO:0043550 19 0.981
positive regulation of lipid kinase activity GO:0090218 13 0.981
system process GO:0003008 349 0.980
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.980
tyrosine phosphorylation of stat protein GO:0007260 33 0.980
negative regulation of phosphate metabolic process GO:0045936 267 0.980
lipid metabolic process GO:0006629 381 0.979
positive regulation of protein kinase b signaling GO:0051897 42 0.979
negative regulation of cell proliferation GO:0008285 228 0.979
endomembrane system organization GO:0010256 196 0.978
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.977
regulation of leukocyte activation GO:0002694 115 0.977
regulation of protein secretion GO:0050708 86 0.977
muscle cell migration GO:0014812 19 0.977
regulation of protein localization GO:0032880 296 0.971
ribonucleotide catabolic process GO:0009261 405 0.969
motor neuron axon guidance GO:0008045 2 0.968
positive regulation of endothelial cell migration GO:0010595 39 0.967
positive regulation of cell adhesion GO:0045785 84 0.966
innate immune response GO:0045087 178 0.965
Fly
immune system development GO:0002520 195 0.964
positive regulation of protein transport GO:0051222 135 0.964
immune response regulating signaling pathway GO:0002764 97 0.964
single organism cellular localization GO:1902580 332 0.963
cellular response to organonitrogen compound GO:0071417 124 0.963
Rat
regulation of leukocyte proliferation GO:0070663 67 0.963
leukocyte differentiation GO:0002521 98 0.963
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.962
cellular component morphogenesis GO:0032989 314 0.960
dephosphorylation GO:0016311 209 0.958
regulation of cell differentiation GO:0045595 393 0.958
negative regulation of protein phosphorylation GO:0001933 140 0.958
behavior GO:0007610 112 0.957
activation of mapk activity GO:0000187 45 0.957
response to wounding GO:0009611 168 0.956
signal transduction by phosphorylation GO:0023014 297 0.955
regulation of vesicle mediated transport GO:0060627 130 0.954
immune response GO:0006955 307 0.953
Fly
regulation of cytokine production GO:0001817 232 0.951
secretion by cell GO:0032940 226 0.950
regulation of erk1 and erk2 cascade GO:0070372 99 0.949
anatomical structure formation involved in morphogenesis GO:0048646 284 0.949
Mouse
response to peptide GO:1901652 65 0.949
Rat
membrane organization GO:0061024 292 0.948
muscle structure development GO:0061061 98 0.948
cellular response to hormone stimulus GO:0032870 125 0.948
Rat
cellular response to peptide GO:1901653 59 0.948
Rat
positive regulation of secretion GO:0051047 116 0.946
positive regulation of cell development GO:0010720 92 0.944
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.944
glycosyl compound catabolic process GO:1901658 413 0.943
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.942
purine ribonucleoside metabolic process GO:0046128 437 0.941
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.941
cell projection organization GO:0030030 252 0.940
Rat
b cell activation GO:0042113 33 0.939
ameboidal type cell migration GO:0001667 135 0.939
regulation of body fluid levels GO:0050878 99 0.938
cellular protein complex assembly GO:0043623 188 0.937
regulation of lipid metabolic process GO:0019216 96 0.935
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.933
negative regulation of programmed cell death GO:0043069 321 0.932
response to oxygen containing compound GO:1901700 369 0.930
Rat
positive regulation of cell differentiation GO:0045597 211 0.930
jak stat cascade GO:0007259 46 0.930
response to growth factor GO:0070848 205 0.929
neuron differentiation GO:0030182 138 0.927
Rat
negative regulation of apoptotic process GO:0043066 316 0.923
cellular response to growth factor stimulus GO:0071363 197 0.923
regulation of protein kinase activity GO:0045859 289 0.922
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.917
taxis GO:0042330 157 0.916
neurogenesis GO:0022008 169 0.916
Rat
positive regulation of cell motility GO:2000147 177 0.916
tube development GO:0035295 125 0.914
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.914
wound healing GO:0042060 115 0.913
mast cell degranulation GO:0043303 4 0.913
regulation of lymphocyte proliferation GO:0050670 64 0.912
hemopoiesis GO:0030097 180 0.912
epithelial cell migration GO:0010631 119 0.911
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.910
cellular macromolecular complex assembly GO:0034622 324 0.910
positive regulation of cytoplasmic transport GO:1903651 82 0.906
positive regulation of neuron projection development GO:0010976 34 0.904
cellular response to peptide hormone stimulus GO:0071375 56 0.904
Rat
cellular ketone metabolic process GO:0042180 80 0.902
cellular response to oxygen containing compound GO:1901701 276 0.900
Rat
striated muscle cell differentiation GO:0051146 43 0.899
purine nucleoside catabolic process GO:0006152 398 0.892
response to drug GO:0042493 81 0.892
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.889
regulation of ion transport GO:0043269 189 0.887
small gtpase mediated signal transduction GO:0007264 78 0.886
activation of immune response GO:0002253 114 0.886
regulation of cell morphogenesis GO:0022604 153 0.886
regulation of protein transport GO:0051223 213 0.883
antigen receptor mediated signaling pathway GO:0050851 38 0.880
positive regulation of intracellular protein transport GO:0090316 76 0.873
regulation of apoptotic signaling pathway GO:2001233 175 0.870
nervous system development GO:0007399 293 0.869
Rat
erk1 and erk2 cascade GO:0070371 104 0.863
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.862
circulatory system development GO:0072359 262 0.858
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 156 0.854
muscle cell differentiation GO:0042692 63 0.853
nucleoside phosphate catabolic process GO:1901292 412 0.851
cellular divalent inorganic cation homeostasis GO:0072503 128 0.850
regulation of wound healing GO:0061041 56 0.849
cell morphogenesis involved in differentiation GO:0000904 144 0.845
glycerophospholipid metabolic process GO:0006650 84 0.844
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.841
mapk cascade GO:0000165 288 0.841
regulation of cytoskeleton organization GO:0051493 177 0.840
epithelium development GO:0060429 227 0.840
regulation of cell activation GO:0050865 125 0.837
post embryonic development GO:0009791 2 0.836
defense response GO:0006952 315 0.835
Fly
negative regulation of cell adhesion GO:0007162 64 0.834
neurological system process GO:0050877 163 0.833
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.827
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.827
cellular response to dna damage stimulus GO:0006974 379 0.826
single organism cell adhesion GO:0098602 179 0.826
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.824
extracellular structure organization GO:0043062 41 0.823
nucleoside triphosphate metabolic process GO:0009141 422 0.823
negative regulation of protein metabolic process GO:0051248 391 0.822
growth GO:0040007 202 0.821
dna replication GO:0006260 116 0.819
Rat
cell type specific apoptotic process GO:0097285 125 0.819
regulation of immune effector process GO:0002697 91 0.814
negative regulation of phosphorylation GO:0042326 174 0.813
synaptic vesicle recycling GO:0036465 3 0.813
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.812
ribonucleoside catabolic process GO:0042454 406 0.808
regulation of protein tyrosine kinase activity GO:0061097 36 0.807
apoptotic signaling pathway GO:0097190 268 0.805
positive regulation of secretion by cell GO:1903532 108 0.804
regulation of response to wounding GO:1903034 101 0.801
regulation of establishment of protein localization GO:0070201 242 0.801
extrinsic apoptotic signaling pathway GO:0097191 119 0.796
myeloid cell differentiation GO:0030099 117 0.792
cytokine production GO:0001816 247 0.784
cell cell signaling GO:0007267 155 0.782
positive regulation of cellular catabolic process GO:0031331 284 0.780
negative regulation of cellular protein metabolic process GO:0032269 353 0.779
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.778
negative regulation of protein kinase activity GO:0006469 98 0.765
negative regulation of cellular amine metabolic process GO:0033239 3 0.763
muscle cell proliferation GO:0033002 35 0.763
Rat
response to nitrogen compound GO:1901698 184 0.749
Rat
negative regulation of apoptotic signaling pathway GO:2001234 97 0.748
neural crest cell migration GO:0001755 2 0.743
tissue morphogenesis GO:0048729 96 0.739
positive regulation of phagocytosis GO:0050766 15 0.727
positive regulation of dna metabolic process GO:0051054 73 0.725
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.724
nerve development GO:0021675 4 0.724
regulation of t cell activation GO:0050863 77 0.723
skeletal system development GO:0001501 79 0.721
regulation of endocytosis GO:0030100 72 0.717
regulation of lymphocyte activation GO:0051249 103 0.712
negative regulation of phosphorus metabolic process GO:0010563 267 0.707
negative regulation of phagocytosis GO:0050765 4 0.706
positive regulation of fibroblast migration GO:0010763 3 0.703
cell junction assembly GO:0034329 67 0.698
nucleoside catabolic process GO:0009164 408 0.697
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 12 0.688
multicellular organismal homeostasis GO:0048871 67 0.686
lipid modification GO:0030258 84 0.684
cell chemotaxis GO:0060326 112 0.683
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.677
intracellular protein transport GO:0006886 270 0.674
response to external biotic stimulus GO:0043207 261 0.673
protein targeting GO:0006605 187 0.669
regulation of calcium ion transport into cytosol GO:0010522 33 0.669
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.668
immune effector process GO:0002252 159 0.668
Fly
regulation of nucleotide catabolic process GO:0030811 205 0.660
positive regulation of cellular amine metabolic process GO:0033240 7 0.657
tissue regeneration GO:0042246 3 0.653
regulation of neurogenesis GO:0050767 82 0.644
t cell activation GO:0042110 99 0.642
organophosphate catabolic process GO:0046434 430 0.635
regulation of cytoplasmic transport GO:1903649 149 0.635
divalent inorganic cation homeostasis GO:0072507 136 0.633
protein import into nucleus GO:0006606 104 0.631
cell projection assembly GO:0030031 126 0.631
positive regulation of protein import into nucleus GO:0042307 46 0.630
forebrain generation of neurons GO:0021872 3 0.626
protein localization to membrane GO:0072657 160 0.623
negative regulation of cell migration GO:0030336 102 0.619
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.616
erbb signaling pathway GO:0038127 44 0.613
Mouse Fly
mitotic cell cycle GO:0000278 326 0.608
blood coagulation GO:0007596 76 0.605
response to peptide hormone GO:0043434 61 0.603
Rat
organ morphogenesis GO:0009887 147 0.600
regulation of endothelial cell apoptotic process GO:2000351 24 0.600
lymphocyte proliferation GO:0046651 70 0.599
positive regulation of exocytosis GO:0045921 35 0.596
regulation of cell growth GO:0001558 135 0.591
purine ribonucleotide catabolic process GO:0009154 404 0.590
regulation of mononuclear cell proliferation GO:0032944 65 0.583
regulation of growth GO:0040008 165 0.582
response to organic cyclic compound GO:0014070 204 0.576
Rat
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.568
peptidyl threonine phosphorylation GO:0018107 41 0.568
regulation of coagulation GO:0050818 44 0.559
purine nucleotide catabolic process GO:0006195 405 0.557
regulation of blood coagulation GO:0030193 42 0.557
receptor mediated endocytosis GO:0006898 84 0.555
negative regulation of kinase activity GO:0033673 106 0.548
phosphatidylinositol metabolic process GO:0046488 53 0.548
endocytosis GO:0006897 159 0.540
platelet activation GO:0030168 44 0.538
chemotaxis GO:0006935 157 0.536
activation of protein kinase activity GO:0032147 90 0.534
osteoclast differentiation GO:0030316 21 0.532
regulation of erbb signaling pathway GO:1901184 27 0.531
positive regulation of cytoskeleton organization GO:0051495 83 0.531
positive regulation of glucose import in response to insulin stimulus GO:2001275 3 0.529
determination of adult lifespan GO:0008340 2 0.529
positive regulation of cell activation GO:0050867 81 0.528
cell morphogenesis GO:0000902 296 0.528
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.525
cellular response to insulin stimulus GO:0032869 41 0.523
Rat
insulin receptor signaling pathway GO:0008286 23 0.523
Rat
cell cell junction organization GO:0045216 69 0.520
positive regulation of neuron differentiation GO:0045666 40 0.519
positive regulation of b cell differentiation GO:0045579 1 0.519
regulation of cardiac muscle cell proliferation GO:0060043 4 0.514
multicellular organismal aging GO:0010259 3 0.510
negative regulation of multicellular organismal process GO:0051241 317 0.508
leukocyte proliferation GO:0070661 74 0.505
neural crest cell development GO:0014032 3 0.503
regulation of calcium ion transport GO:0051924 79 0.502
negative regulation of intracellular signal transduction GO:1902532 183 0.498
peripheral nervous system development GO:0007422 2 0.496
cellular response to growth hormone stimulus GO:0071378 10 0.492
regulation of endothelial cell migration GO:0010594 67 0.488
regulation of epithelial cell migration GO:0010632 93 0.481
protein localization to organelle GO:0033365 280 0.480
hexose transport GO:0008645 30 0.480
metal ion homeostasis GO:0055065 169 0.476
coagulation GO:0050817 78 0.476
cytosolic calcium ion homeostasis GO:0051480 89 0.475
exocytosis GO:0006887 71 0.475
regulation of anatomical structure morphogenesis GO:0022603 286 0.473
glycerolipid biosynthetic process GO:0045017 51 0.471
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.471
stem cell differentiation GO:0048863 93 0.469
positive regulation of epithelial cell proliferation GO:0050679 65 0.468
protein kinase b signaling GO:0043491 69 0.468
cell junction organization GO:0034330 79 0.459
lymphocyte differentiation GO:0030098 35 0.454
regulation of ras protein signal transduction GO:0046578 155 0.454
regulation of intracellular protein transport GO:0033157 123 0.454
melanin metabolic process GO:0006582 1 0.454
Fly
positive regulation of neurogenesis GO:0050769 49 0.453
cellular homeostasis GO:0019725 196 0.451
regulation of gtpase activity GO:0043087 180 0.451
tissue migration GO:0090130 119 0.450
positive regulation of epithelial cell migration GO:0010634 55 0.445
cell matrix adhesion GO:0007160 85 0.443
positive regulation of rac gtpase activity GO:0032855 31 0.439
regulation of protein kinase b signaling GO:0051896 61 0.439
cytoplasmic transport GO:0016482 379 0.437
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.437
fc receptor signaling pathway GO:0038093 2 0.436
regulation of neuron death GO:1901214 56 0.436
negative regulation of catalytic activity GO:0043086 335 0.427
positive regulation of cell cycle GO:0045787 140 0.419
signal transduction in absence of ligand GO:0038034 22 0.416
mast cell activation involved in immune response GO:0002279 4 0.415
positive regulation of leukocyte activation GO:0002696 80 0.413
regulation of cell cycle process GO:0010564 266 0.412
visual learning GO:0008542 1 0.411
ribonucleoside triphosphate catabolic process GO:0009203 391 0.411
astrocyte differentiation GO:0048708 4 0.410
rho protein signal transduction GO:0007266 26 0.410
regulation of neural precursor cell proliferation GO:2000177 4 0.408
myeloid leukocyte activation GO:0002274 34 0.408
stress activated mapk cascade GO:0051403 93 0.406
platelet aggregation GO:0070527 32 0.405
b cell proliferation GO:0042100 22 0.404
regulation of neuron projection development GO:0010975 57 0.394
positive regulation of cytokine production GO:0001819 167 0.393
cell projection morphogenesis GO:0048858 129 0.393
nucleotide catabolic process GO:0009166 408 0.390
positive regulation of protein localization to nucleus GO:1900182 48 0.386
myotube differentiation GO:0014902 22 0.386
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.385
cytokine mediated signaling pathway GO:0019221 109 0.383
negative regulation of epidermal growth factor activated receptor activity GO:0007175 6 0.382
regulation of actin cytoskeleton organization GO:0032956 116 0.382
positive regulation of intracellular transport GO:0032388 104 0.377
muscle tissue development GO:0060537 62 0.376
mitotic cell cycle process GO:1903047 286 0.376
blood vessel maturation GO:0001955 1 0.375
polysaccharide metabolic process GO:0005976 33 0.375
organelle localization GO:0051640 84 0.370
wnt signaling pathway GO:0016055 156 0.368
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.365
actin filament polymerization GO:0030041 45 0.365
glial cell migration GO:0008347 4 0.363
monosaccharide transport GO:0015749 32 0.359
cell substrate adhesion GO:0031589 132 0.358
cardiovascular system development GO:0072358 262 0.355
Mouse
organelle assembly GO:0070925 176 0.352
integrin mediated signaling pathway GO:0007229 32 0.351
positive regulation of endocytosis GO:0045807 42 0.350
generation of neurons GO:0048699 152 0.349
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.348
protein localization to nucleus GO:0034504 136 0.348
protein catabolic process GO:0030163 325 0.347
insulin like growth factor receptor signaling pathway GO:0048009 13 0.347
embryo development GO:0009790 123 0.347
positive regulation of nucleoside metabolic process GO:0045979 186 0.346
developmental growth GO:0048589 48 0.345
positive regulation of catabolic process GO:0009896 310 0.345
angiogenesis GO:0001525 147 0.337
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.335
fibroblast migration GO:0010761 7 0.333
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.333
positive regulation of muscle cell differentiation GO:0051149 15 0.326
cellular metal ion homeostasis GO:0006875 146 0.323
humoral immune response GO:0006959 49 0.323
regulation of nucleotide metabolic process GO:0006140 269 0.323
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.322
positive regulation of angiogenesis GO:0045766 51 0.320
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.317
regulation of cell division GO:0051302 116 0.317
myoblast fusion GO:0007520 1 0.314
blood vessel development GO:0001568 172 0.313
Mouse
positive regulation of glucose transport GO:0010828 17 0.312
mating GO:0007618 1 0.311
branching morphogenesis of an epithelial tube GO:0048754 19 0.310
regulation of dna repair GO:0006282 47 0.309
regulation of striated muscle cell differentiation GO:0051153 25 0.309
regulation of jak stat cascade GO:0046425 44 0.307
lipid biosynthetic process GO:0008610 177 0.307
anatomical structure homeostasis GO:0060249 100 0.307
epidermal growth factor receptor signaling pathway GO:0007173 39 0.306
Mouse Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.304
regulation of glucose import GO:0046324 21 0.303
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.303
regulation of mast cell degranulation GO:0043304 3 0.303
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.302
purine containing compound catabolic process GO:0072523 411 0.302
positive regulation of nervous system development GO:0051962 54 0.301
peptidyl serine modification GO:0018209 106 0.298
regulation of reactive oxygen species metabolic process GO:2000377 41 0.296
negative regulation of transferase activity GO:0051348 124 0.295
photoreceptor cell differentiation GO:0046530 2 0.295
epithelial cell differentiation GO:0030855 141 0.293
organelle fission GO:0048285 149 0.293
regulation of purine nucleotide catabolic process GO:0033121 205 0.293
regulation of proteolysis GO:0030162 293 0.291
cellular calcium ion homeostasis GO:0006874 117 0.290
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.290
muscle cell development GO:0055001 29 0.290
neurotrophin trk receptor signaling pathway GO:0048011 4 0.289
regulation of homeostatic process GO:0032844 121 0.288
ion homeostasis GO:0050801 230 0.285
establishment of protein localization to organelle GO:0072594 172 0.282
central nervous system development GO:0007417 123 0.281
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.280
response to other organism GO:0051707 261 0.279
extracellular matrix organization GO:0030198 41 0.278
leukocyte mediated immunity GO:0002443 59 0.277
i kappab kinase nf kappab signaling GO:0007249 166 0.276
positive regulation of cellular response to insulin stimulus GO:1900078 6 0.273
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.272
t cell receptor signaling pathway GO:0050852 21 0.272
notch signaling pathway GO:0007219 31 0.272
purine ribonucleoside catabolic process GO:0046130 398 0.270
positive regulation of ras gtpase activity GO:0032320 117 0.270
regulation of rho protein signal transduction GO:0035023 79 0.269
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.269
memory GO:0007613 3 0.269
regulation of cell projection organization GO:0031344 107 0.269
neuron death GO:0070997 65 0.268
regulation of response to external stimulus GO:0032101 222 0.267
cellular ion homeostasis GO:0006873 168 0.265
plasma membrane organization GO:0007009 115 0.263
protein secretion GO:0009306 98 0.261
negative regulation of carbohydrate metabolic process GO:0045912 20 0.260
homotypic cell cell adhesion GO:0034109 47 0.257
hindbrain development GO:0030902 3 0.257
response to radiation GO:0009314 151 0.255
anatomical structure maturation GO:0071695 9 0.255
positive regulation of ion transport GO:0043270 87 0.253
regulation of leukocyte mediated immunity GO:0002703 38 0.253
cell growth GO:0016049 160 0.251
regulation of cell junction assembly GO:1901888 29 0.250
positive regulation of cell growth GO:0030307 48 0.247
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.245
carboxylic acid catabolic process GO:0046395 71 0.239
peptidyl tyrosine autophosphorylation GO:0038083 5 0.237
negative regulation of calcium mediated signaling GO:0050849 4 0.237
negative regulation of platelet aggregation GO:0090331 3 0.236
blood vessel morphogenesis GO:0048514 162 0.236
Mouse
modification dependent protein catabolic process GO:0019941 209 0.235
regeneration GO:0031099 4 0.233
Rat
negative regulation of immune response GO:0050777 40 0.232
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 22 0.232
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.230
guanosine containing compound catabolic process GO:1901069 239 0.230
oocyte development GO:0048599 1 0.229
striated muscle tissue development GO:0014706 59 0.229
purine nucleoside triphosphate metabolic process GO:0009144 412 0.228
tor signaling GO:0031929 39 0.228
Fly
syncytium formation by plasma membrane fusion GO:0000768 2 0.227
regulation of actin polymerization or depolymerization GO:0008064 56 0.226
endothelial cell migration GO:0043542 86 0.226
establishment of protein localization to membrane GO:0090150 121 0.226
negative regulation of cell differentiation GO:0045596 171 0.221
protein oligomerization GO:0051259 173 0.218
cognition GO:0050890 43 0.218
peptide hormone secretion GO:0030072 50 0.217
cellular cation homeostasis GO:0030003 163 0.216
glucose import GO:0046323 24 0.216
regulation of interleukin 2 secretion GO:1900040 2 0.216

SHC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.697
cancer DOID:162 167 0.301
organ system cancer DOID:0050686 164 0.291