Homo sapiens

45 known processes

APPL1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

(Aliases: APPL,DIP13alpha)

APPL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of synaptic vesicle transport GO:1902803 3 0.995
regulation of synaptic vesicle exocytosis GO:2000300 2 0.995
cilium assembly GO:0042384 63 0.971
cilium morphogenesis GO:0060271 75 0.967
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.962
ribonucleoside triphosphate metabolic process GO:0009199 412 0.955
glycosyl compound catabolic process GO:1901658 413 0.955
cilium organization GO:0044782 68 0.946
regulation of neurotransmitter secretion GO:0046928 3 0.940
nucleoside catabolic process GO:0009164 408 0.923
receptor internalization GO:0031623 43 0.901
plasma membrane to endosome transport GO:0048227 6 0.894
regulation of endosome size GO:0051036 3 0.878
ribonucleotide catabolic process GO:0009261 405 0.876
neurotransmitter secretion GO:0007269 4 0.825
response to oxygen containing compound GO:1901700 369 0.809
organophosphate catabolic process GO:0046434 430 0.796
purine nucleoside triphosphate catabolic process GO:0009146 392 0.788
cellular ketone metabolic process GO:0042180 80 0.783
chromatin organization GO:0006325 351 0.760
regulation of protein localization to plasma membrane GO:1903076 40 0.724
hexose transport GO:0008645 30 0.715
purine ribonucleoside metabolic process GO:0046128 437 0.712
regulation of cellular amino acid metabolic process GO:0006521 6 0.708
purine nucleoside catabolic process GO:0006152 398 0.616
regulation of cellular amine metabolic process GO:0033238 11 0.596
monosaccharide transport GO:0015749 32 0.591
nucleoside triphosphate metabolic process GO:0009141 422 0.583
exocytosis GO:0006887 71 0.577
regulation of locomotion GO:0040012 329 0.544
post embryonic development GO:0009791 2 0.523
purine ribonucleotide catabolic process GO:0009154 404 0.491
generation of neurons GO:0048699 152 0.481
purine nucleoside triphosphate metabolic process GO:0009144 412 0.475
vesicle mediated transport GO:0016192 371 0.474
cellular component morphogenesis GO:0032989 314 0.463
protein localization to plasma membrane GO:0072659 93 0.426
peptidyl serine phosphorylation GO:0018105 101 0.426
nucleotide catabolic process GO:0009166 408 0.426
membrane organization GO:0061024 292 0.418
positive regulation of cytoplasmic transport GO:1903651 82 0.417
single organism membrane organization GO:0044802 268 0.414
positive regulation of transport GO:0051050 336 0.414
negative regulation of cellular component organization GO:0051129 235 0.399
purine ribonucleoside catabolic process GO:0046130 398 0.392
carbohydrate transport GO:0008643 37 0.392
regulation of cell projection organization GO:0031344 107 0.377
peptidyl serine modification GO:0018209 106 0.369
nucleoside triphosphate catabolic process GO:0009143 394 0.363
regulation of cell motility GO:2000145 299 0.360
regulation of anatomical structure size GO:0090066 101 0.358
gtp catabolic process GO:0006184 237 0.347
lipid metabolic process GO:0006629 381 0.346
cell development GO:0048468 328 0.342
receptor internalization involved in canonical wnt signaling pathway GO:2000286 3 0.342
negative regulation of cellular amine metabolic process GO:0033239 3 0.334
endomembrane system organization GO:0010256 196 0.332
cellular amino acid metabolic process GO:0006520 116 0.320
mitotic cell cycle process GO:1903047 286 0.314
regulation of establishment of protein localization GO:0070201 242 0.313
cell projection organization GO:0030030 252 0.309
cellular response to oxygen containing compound GO:1901701 276 0.308
nervous system development GO:0007399 293 0.305
anatomical structure formation involved in morphogenesis GO:0048646 284 0.302
positive regulation of intracellular transport GO:0032388 104 0.301
purine nucleotide catabolic process GO:0006195 405 0.300
synaptic vesicle exocytosis GO:0016079 3 0.287
neuron projection development GO:0031175 106 0.282
regulation of protein kinase activity GO:0045859 289 0.267
cellular amine metabolic process GO:0044106 41 0.266
single organism cellular localization GO:1902580 332 0.265
canonical wnt signaling pathway GO:0060070 116 0.262
neuron development GO:0048666 113 0.255
regulation of map kinase activity GO:0043405 108 0.254
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.249
cell projection morphogenesis GO:0048858 129 0.242
ribonucleoside catabolic process GO:0042454 406 0.240
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.230
regulation of cell development GO:0060284 161 0.229
positive regulation of early endosome to late endosome transport GO:2000643 3 0.227
regulation of peptidyl serine phosphorylation GO:0033135 50 0.222
endosome organization GO:0007032 20 0.213
positive regulation of cellular component movement GO:0051272 181 0.212
protein localization to membrane GO:0072657 160 0.210
cell division GO:0051301 168 0.206
cellular lipid metabolic process GO:0044255 303 0.197
cell part morphogenesis GO:0032990 137 0.193
negative regulation of phosphorus metabolic process GO:0010563 267 0.190
regulation of viral genome replication GO:0045069 48 0.184
regulation of cellular ketone metabolic process GO:0010565 50 0.184
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.183
negative regulation of axonogenesis GO:0050771 4 0.182
viral process GO:0016032 146 0.181
ribonucleoside triphosphate catabolic process GO:0009203 391 0.180
multicellular organismal aging GO:0010259 3 0.179
glucose metabolic process GO:0006006 45 0.178
nucleosome positioning GO:0016584 3 0.177
cell morphogenesis GO:0000902 296 0.174
phagosome maturation GO:0090382 9 0.169
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.167
chromatin modification GO:0016568 298 0.166
plasma membrane organization GO:0007009 115 0.165
guanosine containing compound metabolic process GO:1901068 244 0.162
negative regulation of phosphorylation GO:0042326 174 0.160
regulation of mitotic cell cycle GO:0007346 189 0.159
regulation of kinase activity GO:0043549 314 0.159
neuron projection morphogenesis GO:0048812 50 0.158
negative regulation of developmental process GO:0051093 247 0.157
regulation of secretion by cell GO:1903530 177 0.157
cytoplasmic transport GO:0016482 379 0.157
endocytosis GO:0006897 159 0.156
amine metabolic process GO:0009308 44 0.154
regulation of exocytosis GO:0017157 46 0.148
neurogenesis GO:0022008 169 0.145
regulation of cellular component movement GO:0051270 334 0.144
secretion GO:0046903 254 0.143
regulation of synaptic plasticity GO:0048167 3 0.142
atp dependent chromatin remodeling GO:0043044 25 0.141
regulation of cytoplasmic transport GO:1903649 149 0.141
nucleoside monophosphate catabolic process GO:0009125 159 0.139
cellular carbohydrate biosynthetic process GO:0034637 21 0.137
purine containing compound catabolic process GO:0072523 411 0.134
wnt signaling pathway GO:0016055 156 0.132
mitotic cell cycle GO:0000278 326 0.130
cellular response to hormone stimulus GO:0032870 125 0.129
regulation of cell migration GO:0030334 289 0.128
regulation of protein localization GO:0032880 296 0.126
multivesicular body assembly GO:0036258 1 0.126
negative regulation of neuron projection development GO:0010977 15 0.125
fatty acid metabolic process GO:0006631 115 0.124
monosaccharide metabolic process GO:0005996 74 0.124
carbohydrate metabolic process GO:0005975 207 0.124
negative regulation of growth GO:0045926 97 0.123
neurotransmitter transport GO:0006836 10 0.123
negative regulation of neurogenesis GO:0050768 26 0.122
negative regulation of catalytic activity GO:0043086 335 0.122
signal release GO:0023061 70 0.121
single organism membrane fusion GO:0044801 37 0.120
growth GO:0040007 202 0.120
lipid modification GO:0030258 84 0.119
cellular response to endogenous stimulus GO:0071495 336 0.116
cellular carbohydrate metabolic process GO:0044262 84 0.115
monocarboxylic acid metabolic process GO:0032787 185 0.114
cell morphogenesis involved in differentiation GO:0000904 144 0.114
regulation of glucose transport GO:0010827 23 0.112
positive regulation of cell migration GO:0030335 172 0.110
positive regulation of cell motility GO:2000147 177 0.103
regulation of neurotransmitter transport GO:0051588 7 0.102
negative regulation of nervous system development GO:0051961 28 0.099
cellular heat acclimation GO:0070370 3 0.097
negative regulation of protein metabolic process GO:0051248 391 0.096
negative regulation of phosphate metabolic process GO:0045936 267 0.095
atp metabolic process GO:0046034 176 0.095
negative regulation of multicellular organismal process GO:0051241 317 0.091
hexose metabolic process GO:0019318 55 0.090
regulation of neurotransmitter levels GO:0001505 15 0.088
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.088
phospholipid metabolic process GO:0006644 99 0.087
locomotory behavior GO:0007626 1 0.086
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.085
ribonucleoside monophosphate metabolic process GO:0009161 187 0.083
negative regulation of cell growth GO:0030308 83 0.082
negative regulation of cell development GO:0010721 48 0.082
tissue migration GO:0090130 119 0.081
cellular response to organonitrogen compound GO:0071417 124 0.081
epithelium migration GO:0090132 119 0.081
ribonucleoside monophosphate catabolic process GO:0009158 158 0.080
negative regulation of mapk cascade GO:0043409 56 0.080
protein catabolic process GO:0030163 325 0.080
response to hormone GO:0009725 175 0.079
regulation of cell growth GO:0001558 135 0.079
tube morphogenesis GO:0035239 95 0.078
response to abiotic stimulus GO:0009628 336 0.078
gtp metabolic process GO:0046039 239 0.077
regulation of protein serine threonine kinase activity GO:0071900 179 0.077
establishment of organelle localization GO:0051656 59 0.076
regulation of intracellular transport GO:0032386 195 0.076
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.075
positive regulation of cellular amine metabolic process GO:0033240 7 0.075
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.074
regulation of cell cycle GO:0051726 393 0.074
mapk cascade GO:0000165 288 0.073
cell fate commitment GO:0045165 27 0.071
purine nucleoside monophosphate catabolic process GO:0009128 158 0.069
establishment of protein localization to membrane GO:0090150 121 0.069
protein localization to organelle GO:0033365 280 0.069
regulation of cell differentiation GO:0045595 393 0.069
organelle localization GO:0051640 84 0.069
embryonic digestive tract morphogenesis GO:0048557 2 0.068
rna interference GO:0016246 4 0.068
regulation of single stranded viral rna replication via double stranded dna intermediate GO:0045091 8 0.067
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.067
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.067
histone acetylation GO:0016573 93 0.067
interspecies interaction between organisms GO:0044419 156 0.067
rostrocaudal neural tube patterning GO:0021903 1 0.066
intracellular protein transport GO:0006886 270 0.065
regulation of chemotaxis GO:0050920 74 0.065
negative regulation of apoptotic process GO:0043066 316 0.065
multi organism cellular process GO:0044764 156 0.064
synaptic transmission GO:0007268 61 0.064
glycerolipid metabolic process GO:0046486 107 0.064
macromolecule methylation GO:0043414 97 0.063
cell cell signaling GO:0007267 155 0.063
negative regulation of protein kinase activity GO:0006469 98 0.062
nucleoside phosphate catabolic process GO:1901292 412 0.062
regulation of cellular component size GO:0032535 82 0.062
rab protein signal transduction GO:0032482 4 0.061
negative regulation of transferase activity GO:0051348 124 0.061
regulation of growth GO:0040008 165 0.060
neuron differentiation GO:0030182 138 0.060
taxis GO:0042330 157 0.059
regulation of neuron differentiation GO:0045664 70 0.058
glycogen metabolic process GO:0005977 22 0.058
negative regulation of protein phosphorylation GO:0001933 140 0.057
regulation of transferase activity GO:0051338 355 0.057
regulation of gene expression epigenetic GO:0040029 73 0.056
regulation of secretion GO:0051046 194 0.056
nucleoside monophosphate metabolic process GO:0009123 191 0.055
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.054
regulation of protein transport GO:0051223 213 0.054
regulation of receptor mediated endocytosis GO:0048259 32 0.054
positive regulation of epithelial cell migration GO:0010634 55 0.053
positive regulation of cell proliferation GO:0008284 301 0.053
signal transduction by phosphorylation GO:0023014 297 0.053
purine nucleoside monophosphate metabolic process GO:0009126 186 0.053
positive regulation of locomotion GO:0040017 186 0.052
vesicle organization GO:0016050 62 0.052
response to inorganic substance GO:0010035 127 0.052
negative regulation of map kinase activity GO:0043407 27 0.052
oogenesis GO:0048477 2 0.051
determination of adult lifespan GO:0008340 2 0.051
cell growth GO:0016049 160 0.051
negative regulation of cell differentiation GO:0045596 171 0.050
regulation of neuron projection development GO:0010975 57 0.049
embryonic morphogenesis GO:0048598 85 0.049
chromatin remodeling GO:0006338 55 0.049
single stranded viral rna replication via double stranded dna intermediate GO:0039692 9 0.048
regulation of intracellular protein transport GO:0033157 123 0.048
regulation of epithelial cell migration GO:0010632 93 0.048
organelle fusion GO:0048284 36 0.048
positive regulation of catabolic process GO:0009896 310 0.047
regulation of cellular response to stress GO:0080135 244 0.046
regulation of cell cycle process GO:0010564 266 0.046
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.046
regulation of neurogenesis GO:0050767 82 0.046
negative regulation of programmed cell death GO:0043069 321 0.046
organic hydroxy compound metabolic process GO:1901615 147 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
negative regulation of neuron differentiation GO:0045665 21 0.046
regulation of cytoskeleton organization GO:0051493 177 0.045
glycogen biosynthetic process GO:0005978 16 0.045
epithelial cell migration GO:0010631 119 0.045
organelle assembly GO:0070925 176 0.044
regulation of endocytosis GO:0030100 72 0.044
dephosphorylation GO:0016311 209 0.044
cytokinesis GO:0000910 96 0.043
organ morphogenesis GO:0009887 147 0.043
filopodium assembly GO:0046847 18 0.042
histone deacetylation GO:0016575 32 0.042
fatty acid oxidation GO:0019395 31 0.042
regulation of mapk cascade GO:0043408 262 0.042
peptidyl lysine acetylation GO:0018394 101 0.041
response to organic cyclic compound GO:0014070 204 0.041
internal peptidyl lysine acetylation GO:0018393 97 0.041
embryonic epithelial tube formation GO:0001838 4 0.041
ameboidal type cell migration GO:0001667 135 0.040
chemotaxis GO:0006935 157 0.040
negative regulation of cell projection organization GO:0031345 22 0.039
regulation of nervous system development GO:0051960 88 0.039
response to wounding GO:0009611 168 0.039
photoreceptor cell differentiation GO:0046530 2 0.039
memory GO:0007613 3 0.039
single organism carbohydrate metabolic process GO:0044723 193 0.038
epithelium development GO:0060429 227 0.038
neural tube formation GO:0001841 3 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
nuclear division GO:0000280 128 0.037
organelle fission GO:0048285 149 0.037
atp catabolic process GO:0006200 157 0.037
cellular macromolecule catabolic process GO:0044265 380 0.037
cellular protein catabolic process GO:0044257 261 0.037
cell projection assembly GO:0030031 126 0.037
digestive tract development GO:0048565 75 0.036
cellular polysaccharide biosynthetic process GO:0033692 21 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
segmentation GO:0035282 4 0.036
phosphatidylinositol metabolic process GO:0046488 53 0.036
protein ubiquitination GO:0016567 314 0.036
circulatory system development GO:0072359 262 0.035
nitrogen compound transport GO:0071705 191 0.035
negative regulation of intracellular signal transduction GO:1902532 183 0.035
endosomal transport GO:0016197 129 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.035
response to oxidative stress GO:0006979 121 0.035
protein modification by small protein conjugation GO:0032446 342 0.035
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.035
small molecule catabolic process GO:0044282 92 0.035
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.034
wound healing GO:0042060 115 0.033
axonogenesis GO:0007409 31 0.033
cellular glucan metabolic process GO:0006073 22 0.033
negative regulation of cell proliferation GO:0008285 228 0.033
proteasomal protein catabolic process GO:0010498 176 0.033
regulation of synaptic transmission GO:0050804 11 0.033
cell type specific apoptotic process GO:0097285 125 0.033
oocyte differentiation GO:0009994 2 0.033
covalent chromatin modification GO:0016569 254 0.033
establishment of vesicle localization GO:0051650 23 0.033
peptidyl lysine modification GO:0018205 144 0.033
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.032
ras protein signal transduction GO:0007265 73 0.032
maintenance of location GO:0051235 112 0.032
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.032
mesendoderm development GO:0048382 1 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.031
nucleosome assembly GO:0006334 50 0.031
axon cargo transport GO:0008088 2 0.031
embryo development GO:0009790 123 0.031
histone modification GO:0016570 251 0.030
negative regulation of protein modification process GO:0031400 200 0.030
gene silencing GO:0016458 49 0.030
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.030
glycerophospholipid metabolic process GO:0006650 84 0.030
protein kinase b signaling GO:0043491 69 0.029
negative regulation of cellular component movement GO:0051271 106 0.029
double strand break repair GO:0006302 101 0.029
tissue regeneration GO:0042246 3 0.029
carbohydrate biosynthetic process GO:0016051 42 0.028
organophosphate biosynthetic process GO:0090407 163 0.028
negative regulation of neuron apoptotic process GO:0043524 23 0.028
developmental growth GO:0048589 48 0.028
regulation of endothelial cell migration GO:0010594 67 0.028
membrane fusion GO:0061025 43 0.028
regulation of carbohydrate metabolic process GO:0006109 54 0.028
regulation of dna metabolic process GO:0051052 153 0.027
modulation by host of viral transcription GO:0043921 20 0.027
mitotic nuclear division GO:0007067 119 0.027
autophagy GO:0006914 88 0.027
negative regulation of transport GO:0051051 176 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
embryonic hemopoiesis GO:0035162 4 0.027
head development GO:0060322 108 0.027
synaptic vesicle localization GO:0097479 5 0.026
female gamete generation GO:0007292 2 0.026
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.026
positive regulation of smooth muscle cell migration GO:0014911 6 0.026
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.026
aging GO:0007568 66 0.026
secretion by cell GO:0032940 226 0.025
rhythmic behavior GO:0007622 2 0.025
response to insulin GO:0032868 45 0.025
cellular component assembly involved in morphogenesis GO:0010927 73 0.025
regulation of viral process GO:0050792 103 0.024
positive regulation of cell death GO:0010942 263 0.024
regulation of neuronal synaptic plasticity GO:0048168 1 0.024
protein acetylation GO:0006473 116 0.024
positive regulation of cellular component organization GO:0051130 376 0.024
negative regulation of organelle organization GO:0010639 126 0.024
energy reserve metabolic process GO:0006112 22 0.024
hindbrain development GO:0030902 3 0.024
peptidyl threonine modification GO:0018210 45 0.024
receptor mediated endocytosis GO:0006898 84 0.024
regulation of cell projection assembly GO:0060491 47 0.024
modification of morphology or physiology of other organism GO:0035821 43 0.023
synaptic vesicle recycling GO:0036465 3 0.023
regulation of ion transport GO:0043269 189 0.023
response to metal ion GO:0010038 84 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
muscle organ development GO:0007517 56 0.023
brain development GO:0007420 97 0.023
neuromuscular junction development GO:0007528 3 0.023
heat acclimation GO:0010286 3 0.023
regulation of smooth muscle cell proliferation GO:0048660 28 0.023
positive regulation of dna metabolic process GO:0051054 73 0.023
chromosome segregation GO:0007059 114 0.023
dna conformation change GO:0071103 113 0.023
posttranscriptional gene silencing by rna GO:0035194 25 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
organic hydroxy compound catabolic process GO:1901616 22 0.022
cytoskeleton dependent cytokinesis GO:0061640 22 0.022
establishment of protein localization to organelle GO:0072594 172 0.022
regulation of axon guidance GO:1902667 3 0.022
response to nitrogen compound GO:1901698 184 0.022
viral life cycle GO:0019058 132 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
modification dependent protein catabolic process GO:0019941 209 0.021
cellular homeostasis GO:0019725 196 0.021
endothelial cell proliferation GO:0001935 65 0.021
negative regulation of kinase activity GO:0033673 106 0.021
muscle cell proliferation GO:0033002 35 0.021
protein acylation GO:0043543 138 0.020
vesicle localization GO:0051648 26 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
negative regulation of mitotic cell cycle GO:0045930 102 0.020
regulation of jnk cascade GO:0046328 73 0.020
meiotic chromosome segregation GO:0045132 4 0.020
developmental cell growth GO:0048588 18 0.019
chemical homeostasis GO:0048878 306 0.019
circadian behavior GO:0048512 2 0.019
associative learning GO:0008306 1 0.019
dna packaging GO:0006323 77 0.019
positive regulation of endocytosis GO:0045807 42 0.019
digestive tract morphogenesis GO:0048546 56 0.019
histone methylation GO:0016571 60 0.019
lipid catabolic process GO:0016042 84 0.018
cellular component disassembly GO:0022411 92 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
single organism reproductive process GO:0044702 98 0.018
cell adhesion GO:0007155 325 0.018
mating GO:0007618 1 0.018
negative regulation of cell migration GO:0030336 102 0.018
immune effector process GO:0002252 159 0.018
regulation of protein targeting GO:1903533 91 0.018
cellular response to insulin stimulus GO:0032869 41 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
regulation of cell morphogenesis GO:0022604 153 0.017
angiogenesis GO:0001525 147 0.017
positive regulation of cell development GO:0010720 92 0.017
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
negative regulation of apoptotic signaling pathway GO:2001234 97 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
positive regulation of dendrite morphogenesis GO:0050775 3 0.017
positive regulation of gtpase activity GO:0043547 166 0.017
regulation of behavior GO:0050795 82 0.016
system process GO:0003008 349 0.016
dna repair GO:0006281 198 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
protein targeting GO:0006605 187 0.016
axon development GO:0061564 34 0.016
glucan biosynthetic process GO:0009250 16 0.016
late endosome to vacuole transport GO:0045324 2 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
regulation of transporter activity GO:0032409 82 0.016
stress activated mapk cascade GO:0051403 93 0.016
multivesicular body organization GO:0036257 2 0.016
synaptic vesicle endocytosis GO:0048488 2 0.016
oxidation reduction process GO:0055114 396 0.016
positive regulation of immune system process GO:0002684 283 0.016
positive regulation of intracellular protein transport GO:0090316 76 0.016
negative regulation by host of viral transcription GO:0043922 12 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
protein dna complex assembly GO:0065004 64 0.016
mitotic cytokinesis GO:0000281 19 0.016
response to virus GO:0009615 126 0.016
response to cytokine GO:0034097 232 0.015
regulation of transmembrane transporter activity GO:0022898 74 0.015
positive regulation of secretion GO:0051047 116 0.015
somitogenesis GO:0001756 2 0.015
neuron death GO:0070997 65 0.015
negative regulation of peptidyl serine phosphorylation GO:0033137 8 0.015
regulation of ras protein signal transduction GO:0046578 155 0.015
sleep GO:0030431 2 0.015
chromatin silencing GO:0006342 12 0.015
regulation of protein kinase b signaling GO:0051896 61 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
polysaccharide metabolic process GO:0005976 33 0.015
meiosis i GO:0007127 4 0.015
cellular ion homeostasis GO:0006873 168 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
protein secretion GO:0009306 98 0.015
phagocytosis GO:0006909 42 0.014
polysaccharide biosynthetic process GO:0000271 27 0.014
regulation of generation of precursor metabolites and energy GO:0043467 27 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
regulation of transmembrane transport GO:0034762 139 0.014
mitotic sister chromatid segregation GO:0000070 53 0.014
central nervous system development GO:0007417 123 0.014
cellular response to peptide hormone stimulus GO:0071375 56 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
metal ion transport GO:0030001 272 0.014
muscle structure development GO:0061061 98 0.014
regulation of cellular response to insulin stimulus GO:1900076 17 0.014
regulation of response to external stimulus GO:0032101 222 0.013
regulation of axonogenesis GO:0050770 16 0.013
rna replication GO:0039703 9 0.013
alcohol metabolic process GO:0006066 114 0.013
antigen processing and presentation GO:0019882 33 0.013
nuclear transport GO:0051169 179 0.013
positive regulation of transferase activity GO:0051347 227 0.013
pituitary gland development GO:0021983 2 0.013
response to lipid GO:0033993 206 0.013

APPL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
glycogen storage disease DOID:2747 10 0.114
disease of metabolism DOID:0014667 295 0.114
carbohydrate metabolic disorder DOID:2978 55 0.114
glycogen metabolism disorder DOID:0050728 10 0.114
inherited metabolic disorder DOID:655 242 0.114
disease of cellular proliferation DOID:14566 174 0.094
cancer DOID:162 167 0.088
organ system cancer DOID:0050686 164 0.088
musculoskeletal system disease DOID:17 223 0.047
muscular disease DOID:0080000 114 0.030
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020