IMP

Process View

Homo sapiens

1 genes annotated in human

mesendoderm development

The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesendoderm development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesendoderm development" (in gray)

Name	Description	Probability	Func Analog Organism
CTNND1	catenin (cadherin-associated protein), delta 1	1.000
BMP2	bone morphogenetic protein 2	1.000
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	1.000
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	1.000
BMPR1B	bone morphogenetic protein receptor, type IB	0.997
JUP	junction plakoglobin	0.994
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.975	Zebrafish
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.965
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.958
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.919	Zebrafish
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.916
NOG	noggin	0.814
GLIS2	GLIS family zinc finger 2	0.678
FRMD5	FERM domain containing 5	0.436
EGFR	epidermal growth factor receptor	0.377
BMP4	bone morphogenetic protein 4	0.358
ACTN4	actinin, alpha 4	0.290
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.281
PLEKHA7	pleckstrin homology domain containing, family A member 7	0.212
PRKCA	protein kinase C, alpha	0.151
MUC1	mucin 1, cell surface associated	0.149
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.137
CTNNBIP1	catenin, beta interacting protein 1	0.111
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.084
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.077
APC	adenomatous polyposis coli	0.077
COL2A1	collagen, type II, alpha 1	0.074
PVR	poliovirus receptor	0.059
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.049
GJD2	gap junction protein, delta 2, 36kDa	0.048
PITX2	paired-like homeodomain 2	0.047	Zebrafish
BTRC	beta-transducin repeat containing	0.044
PSEN1	presenilin 1	0.038
PRKG1	protein kinase, cGMP-dependent, type I	0.034
DSP	desmoplakin	0.034
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.032
ESRP1	epithelial splicing regulatory protein 1	0.032
NDRG1	N-myc downstream regulated 1	0.032
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.032
DOK5	docking protein 5	0.030
TCF4	transcription factor 4	0.030
EMD	emerin	0.029
TGFA	transforming growth factor, alpha	0.029
PPL	periplakin	0.028
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.027
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.026
FOXF2	forkhead box F2	0.026
COL17A1	collagen, type XVII, alpha 1	0.025
EGF	epidermal growth factor	0.025
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.025
HSPA1B	heat shock 70kDa protein 1B	0.024
ACAN	aggrecan	0.024
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.024
HOXA1	homeobox A1	0.023
BMP8A	bone morphogenetic protein 8a	0.023	Human
SOX1	SRY (sex determining region Y)-box 1	0.023
SPINT2	serine peptidase inhibitor, Kunitz type, 2	0.022
RAB25	RAB25, member RAS oncogene family	0.021
EFNB3	ephrin-B3	0.021
PRPH	peripherin	0.020
PYY	peptide YY	0.020
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.020
DLX5	distal-less homeobox 5	0.020
HOXB8	homeobox B8	0.019
AXIN1	axin 1	0.019
HOXC8	homeobox C8	0.019
FZD10	frizzled homolog 10 (Drosophila)	0.019
PTPRF	protein tyrosine phosphatase, receptor type, F	0.018
APC2	adenomatosis polyposis coli 2	0.018
NPPC	natriuretic peptide C	0.018
PRKD1	protein kinase D1	0.018
NTN1	netrin 1	0.017
NOS1	nitric oxide synthase 1 (neuronal)	0.017
HAND1	heart and neural crest derivatives expressed 1	0.017
SOX21	SRY (sex determining region Y)-box 21	0.017
RELN	reelin	0.017
PRSS8	protease, serine, 8	0.017
ITGB4	integrin, beta 4	0.017
CYP2F1	cytochrome P450, family 2, subfamily F, polypeptide 1	0.017
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.017
FOXF1	forkhead box F1	0.017
BMP7	bone morphogenetic protein 7	0.017	Human
KRT6A	keratin 6A	0.017
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.016
SOSTDC1	sclerostin domain containing 1	0.016
ACVR1	activin A receptor, type I	0.016
GRHL2	grainyhead-like 2 (Drosophila)	0.016
AR	androgen receptor	0.016
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.016
RB1	retinoblastoma 1	0.016
GRB10	growth factor receptor-bound protein 10	0.015
HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	0.015
NIPSNAP1	nipsnap homolog 1 (C. elegans)	0.015
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.015
FOXC1	forkhead box C1	0.015
TRIM29	tripartite motif containing 29	0.015
TG	thyroglobulin	0.015
PDZK1	PDZ domain containing 1	0.015
HOXD10	homeobox D10	0.015
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.015
PTK7	PTK7 protein tyrosine kinase 7	0.015
NPY2R	neuropeptide Y receptor Y2	0.014
FOXD3	forkhead box D3	0.014
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.014
ADRBK1	adrenergic, beta, receptor kinase 1	0.014
COL13A1	collagen, type XIII, alpha 1	0.014
HOXD11	homeobox D11	0.014
ITGB6	integrin, beta 6	0.014
WNT6	wingless-type MMTV integration site family, member 6	0.014
FGF16	fibroblast growth factor 16	0.014
C11orf20	chromosome 11 open reading frame 20	0.014
LECT1	leukocyte cell derived chemotaxin 1	0.013
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.013
REG3A	regenerating islet-derived 3 alpha	0.013
WNT11	wingless-type MMTV integration site family, member 11	0.013
NXPH3	neurexophilin 3	0.013
FGD1	FYVE, RhoGEF and PH domain containing 1	0.013
GPR143	G protein-coupled receptor 143	0.013
PDE7B	phosphodiesterase 7B	0.013
CSHL1	chorionic somatomammotropin hormone-like 1	0.013
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.013
CXADR	coxsackie virus and adenovirus receptor	0.013
DLX4	distal-less homeobox 4	0.013
TNS4	tensin 4	0.013
ZMYND11	zinc finger, MYND-type containing 11	0.012
PSORS1C2	psoriasis susceptibility 1 candidate 2	0.012
DSC3	desmocollin 3	0.012
S100A7	S100 calcium binding protein A7	0.012
EPCAM	epithelial cell adhesion molecule	0.012
ST14	suppression of tumorigenicity 14 (colon carcinoma)	0.012
NKX3-2	NK3 homeobox 2	0.012
ACVR2B	activin A receptor, type IIB	0.012
EFNA2	ephrin-A2	0.012
DMRT1	doublesex and mab-3 related transcription factor 1	0.012
BHLHE22	basic helix-loop-helix family, member e22	0.012
EDN3	endothelin 3	0.012
ESRP2	epithelial splicing regulatory protein 2	0.012
PMEL	premelanosome protein	0.012
GDNF	glial cell derived neurotrophic factor	0.012
PLEKHA4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.012
KRT1	keratin 1	0.011
CLDN17	claudin 17	0.011
AFP	alpha-fetoprotein	0.011
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.011
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.011
TMEM30B	transmembrane protein 30B	0.011
CRTAC1	cartilage acidic protein 1	0.011
SOD3	superoxide dismutase 3, extracellular	0.011
EN2	engrailed homeobox 2	0.011
HOXB13	homeobox B13	0.011
KRT19	keratin 19	0.011
EYA2	eyes absent homolog 2 (Drosophila)	0.011
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.011
BMP3	bone morphogenetic protein 3	0.011	Human
PDE6G	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.011
FXYD3	FXYD domain containing ion transport regulator 3	0.011
SOX14	SRY (sex determining region Y)-box 14	0.011
OLIG2	oligodendrocyte lineage transcription factor 2	0.011
GDF9	growth differentiation factor 9	0.011
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	0.011
FOLR3	folate receptor 3 (gamma)	0.011
WNT2	wingless-type MMTV integration site family member 2	0.011
RUNX2	runt-related transcription factor 2	0.011
NGF	nerve growth factor (beta polypeptide)	0.011
OVOL2	ovo-like 2 (Drosophila)	0.011
ALX4	ALX homeobox 4	0.011
C8orf84	chromosome 8 open reading frame 84	0.011
IL1RL2	interleukin 1 receptor-like 2	0.010
CST1	cystatin SN	0.010
GPR50	G protein-coupled receptor 50	0.010
SCUBE3	signal peptide, CUB domain, EGF-like 3	0.010
ZBTB33	zinc finger and BTB domain containing 33	0.010
SMAD6	SMAD family member 6	0.010
TM4SF4	transmembrane 4 L six family member 4	0.010
LAD1	ladinin 1	0.010
PRPH2	peripherin 2 (retinal degeneration, slow)	0.010