Homo sapiens

215 known processes

TLR3

toll-like receptor 3

(Aliases: CD283)

TLR3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 315 0.367
Human Mouse Fly
regulation of response to external stimulus GO:0032101 222 0.275
Fly
lipid metabolic process GO:0006629 381 0.254
positive regulation of cytokine production GO:0001819 167 0.237
cellular lipid metabolic process GO:0044255 303 0.229
regulation of cellular amine metabolic process GO:0033238 11 0.218
response to other organism GO:0051707 261 0.187
Human Zebrafish Mouse Fly
response to external biotic stimulus GO:0043207 261 0.163
Human Zebrafish Mouse Fly
cellular amino acid metabolic process GO:0006520 116 0.155
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.155
positive regulation of immune system process GO:0002684 283 0.146
response to biotic stimulus GO:0009607 276 0.145
Human Zebrafish Mouse Fly
positive regulation of phosphorylation GO:0042327 394 0.144
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.140
cellular amine metabolic process GO:0044106 41 0.134
regulation of cellular ketone metabolic process GO:0010565 50 0.130
positive regulation of cell proliferation GO:0008284 301 0.127
innate immune response GO:0045087 178 0.124
negative regulation of apoptotic process GO:0043066 316 0.114
regulation of establishment of protein localization GO:0070201 242 0.110
immune effector process GO:0002252 159 0.108
Human Mouse Fly
immune response GO:0006955 307 0.108
Fly
regulation of kinase activity GO:0043549 314 0.103
regulation of locomotion GO:0040012 329 0.100
cellular ketone metabolic process GO:0042180 80 0.098
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.095
regulation of transferase activity GO:0051338 355 0.095
positive regulation of cell motility GO:2000147 177 0.092
regulation of protein kinase activity GO:0045859 289 0.088
regulation of immune response GO:0050776 201 0.086
cell chemotaxis GO:0060326 112 0.085
intracellular protein transport GO:0006886 270 0.084
positive regulation of kinase activity GO:0033674 204 0.081
regulation of immune effector process GO:0002697 91 0.080
Fly
negative regulation of programmed cell death GO:0043069 321 0.080
cytokine production GO:0001816 247 0.079
positive regulation of transport GO:0051050 336 0.079
cellular homeostasis GO:0019725 196 0.078
regulation of cytokine production GO:0001817 232 0.077
positive regulation of protein kinase activity GO:0045860 190 0.077
regulation of defense response GO:0031347 154 0.076
immune response regulating signaling pathway GO:0002764 97 0.075
positive regulation of leukocyte activation GO:0002696 80 0.074
activation of innate immune response GO:0002218 55 0.073
glycerolipid biosynthetic process GO:0045017 51 0.072
lipid biosynthetic process GO:0008610 177 0.072
negative regulation of cell death GO:0060548 345 0.071
amine metabolic process GO:0009308 44 0.071
pattern recognition receptor signaling pathway GO:0002221 48 0.070
transmembrane transport GO:0055085 399 0.070
multi organism cellular process GO:0044764 156 0.070
positive regulation of transferase activity GO:0051347 227 0.070
secretion GO:0046903 254 0.068
regulation of synaptic plasticity GO:0048167 3 0.068
chemical homeostasis GO:0048878 306 0.066
regulation of protein localization GO:0032880 296 0.066
phospholipid metabolic process GO:0006644 99 0.064
activation of immune response GO:0002253 114 0.063
positive regulation of locomotion GO:0040017 186 0.063
positive regulation of innate immune response GO:0045089 79 0.062
vesicle mediated transport GO:0016192 371 0.061
regulation of cellular amino acid metabolic process GO:0006521 6 0.060
cation transport GO:0006812 331 0.059
cell activation GO:0001775 213 0.059
interspecies interaction between organisms GO:0044419 156 0.059
g protein coupled receptor signaling pathway GO:0007186 207 0.059
metal ion transport GO:0030001 272 0.059
regulation of cell motility GO:2000145 299 0.058
post embryonic development GO:0009791 2 0.056
response to virus GO:0009615 126 0.056
Human Zebrafish Mouse Fly
behavior GO:0007610 112 0.056
cation homeostasis GO:0055080 189 0.055
response to oxygen containing compound GO:1901700 369 0.055
regulation of cell differentiation GO:0045595 393 0.054
response to lipid GO:0033993 206 0.054
ion transmembrane transport GO:0034220 338 0.052
system process GO:0003008 349 0.052
determination of adult lifespan GO:0008340 2 0.052
positive regulation of map kinase activity GO:0043406 80 0.051
regulation of multi organism process GO:0043900 157 0.051
Fly
multicellular organismal aging GO:0010259 3 0.050
regulation of cell activation GO:0050865 125 0.050
regulation of protein transport GO:0051223 213 0.050
leukocyte activation GO:0045321 164 0.050
innate immune response activating signal transduction GO:0002758 48 0.049
oogenesis GO:0048477 2 0.049
calcium ion homeostasis GO:0055074 122 0.049
hematopoietic or lymphoid organ development GO:0048534 186 0.049
cellular chemical homeostasis GO:0055082 180 0.049
defense response to other organism GO:0098542 129 0.048
Human Mouse Fly
leukocyte differentiation GO:0002521 98 0.048
cellular cation homeostasis GO:0030003 163 0.048
positive regulation of secretion by cell GO:1903532 108 0.047
divalent inorganic cation homeostasis GO:0072507 136 0.046
glycerolipid metabolic process GO:0046486 107 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.045
cellular ion homeostasis GO:0006873 168 0.044
positive regulation of protein phosphorylation GO:0001934 313 0.044
positive regulation of behavior GO:0048520 60 0.043
positive regulation of response to external stimulus GO:0032103 88 0.043
signal transduction by phosphorylation GO:0023014 297 0.043
Mouse
positive regulation of apoptotic process GO:0043065 246 0.042
anion transport GO:0006820 161 0.042
ion homeostasis GO:0050801 230 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.042
positive regulation of immune response GO:0050778 159 0.041
regulation of t cell activation GO:0050863 77 0.041
rho protein signal transduction GO:0007266 26 0.041
regulation of behavior GO:0050795 82 0.041
locomotory behavior GO:0007626 1 0.040
positive regulation of cellular component organization GO:0051130 376 0.040
cell adhesion GO:0007155 325 0.039
Fly
regulation of nucleocytoplasmic transport GO:0046822 98 0.039
biological adhesion GO:0022610 331 0.039
Fly
regulation of protein secretion GO:0050708 86 0.039
metal ion homeostasis GO:0055065 169 0.039
i kappab kinase nf kappab signaling GO:0007249 166 0.038
positive regulation of intracellular protein transport GO:0090316 76 0.038
reactive oxygen species metabolic process GO:0072593 75 0.037
hemopoiesis GO:0030097 180 0.037
immune system development GO:0002520 195 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.037
viral process GO:0016032 146 0.037
taxis GO:0042330 157 0.036
response to cytokine GO:0034097 232 0.036
viral life cycle GO:0019058 132 0.036
protein secretion GO:0009306 98 0.036
negative regulation of protein metabolic process GO:0051248 391 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
single organism cellular localization GO:1902580 332 0.035
mapk cascade GO:0000165 288 0.035
Mouse
regulation of secretion by cell GO:1903530 177 0.035
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.035
regulation of cell adhesion GO:0030155 166 0.035
apoptotic signaling pathway GO:0097190 268 0.035
positive regulation of t cell proliferation GO:0042102 33 0.035
positive regulation of leukocyte proliferation GO:0070665 48 0.035
regulation of cell cycle GO:0051726 393 0.035
blood vessel morphogenesis GO:0048514 162 0.035
response to oxidative stress GO:0006979 121 0.035
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 3 0.035
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.034
regulation of cell migration GO:0030334 289 0.034
phosphatidylinositol metabolic process GO:0046488 53 0.034
response to nitrogen compound GO:1901698 184 0.034
carbohydrate metabolic process GO:0005975 207 0.034
cellular response to organic cyclic compound GO:0071407 127 0.034
regulation of cellular component movement GO:0051270 334 0.033
regulation of leukocyte proliferation GO:0070663 67 0.033
regulation of secretion GO:0051046 194 0.033
positive regulation of mapk cascade GO:0043410 190 0.033
Mouse
regulation of mapk cascade GO:0043408 262 0.033
Mouse
intracellular receptor signaling pathway GO:0030522 104 0.033
positive regulation of developmental process GO:0051094 314 0.033
negative regulation of cell proliferation GO:0008285 228 0.032
protein maturation GO:0051604 233 0.032
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
positive regulation of cell migration GO:0030335 172 0.032
immune response activating signal transduction GO:0002757 90 0.032
myeloid cell differentiation GO:0030099 117 0.032
cellular response to oxygen containing compound GO:1901701 276 0.032
regulation of ion transport GO:0043269 189 0.032
fatty acid metabolic process GO:0006631 115 0.032
phosphatidylinositol mediated signaling GO:0048015 55 0.032
glycosyl compound catabolic process GO:1901658 413 0.032
glycerophospholipid metabolic process GO:0006650 84 0.032
cellular metal ion homeostasis GO:0006875 146 0.031
positive regulation of cell death GO:0010942 263 0.031
secretion by cell GO:0032940 226 0.031
ribonucleotide catabolic process GO:0009261 405 0.030
cell fate determination GO:0001709 3 0.030
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.030
protein localization to organelle GO:0033365 280 0.030
enzyme linked receptor protein signaling pathway GO:0007167 303 0.030
response to wounding GO:0009611 168 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.029
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.029
organic acid biosynthetic process GO:0016053 97 0.029
purine containing compound catabolic process GO:0072523 411 0.029
circulatory system development GO:0072359 262 0.029
activation of protein kinase activity GO:0032147 90 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.029
positive regulation of mononuclear cell proliferation GO:0032946 47 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.028
divalent metal ion transport GO:0070838 152 0.028
positive regulation of lymphocyte activation GO:0051251 73 0.028
mitotic cell cycle GO:0000278 326 0.028
regulation of transmembrane transport GO:0034762 139 0.028
regulation of neuronal synaptic plasticity GO:0048168 1 0.028
regulation of binding GO:0051098 111 0.028
positive regulation of lymphocyte proliferation GO:0050671 46 0.027
cytosolic calcium ion homeostasis GO:0051480 89 0.027
response to organic cyclic compound GO:0014070 204 0.027
cellular calcium ion homeostasis GO:0006874 117 0.027
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
regulation of proteolysis GO:0030162 293 0.027
cellular response to endogenous stimulus GO:0071495 336 0.027
chemotaxis GO:0006935 157 0.027
defense response to virus GO:0051607 71 0.026
Human Mouse Fly
response to molecule of bacterial origin GO:0002237 82 0.026
anatomical structure homeostasis GO:0060249 100 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
sequestering of calcium ion GO:0051208 17 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
lymphocyte activation GO:0046649 133 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
cell development GO:0048468 328 0.025
spermatid development GO:0007286 4 0.025
single organism cell adhesion GO:0098602 179 0.025
leukocyte chemotaxis GO:0030595 76 0.025
sensory perception of pain GO:0019233 4 0.025
spermatid differentiation GO:0048515 4 0.025
female gamete generation GO:0007292 2 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.024
glycerophospholipid biosynthetic process GO:0046474 40 0.024
regulation of map kinase activity GO:0043405 108 0.024
nuclear transport GO:0051169 179 0.024
protein targeting GO:0006605 187 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
positive regulation of programmed cell death GO:0043068 249 0.024
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.024
Mouse
regulation of protein binding GO:0043393 66 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
regulation of chemotaxis GO:0050920 74 0.024
negative regulation of multi organism process GO:0043901 92 0.024
negative regulation of response to external stimulus GO:0032102 83 0.024
interferon gamma production GO:0032609 39 0.024
regulation of tumor necrosis factor production GO:0032680 43 0.024
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
startle response GO:0001964 3 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.023
cell type specific apoptotic process GO:0097285 125 0.023
cellular component morphogenesis GO:0032989 314 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
sequestering of metal ion GO:0051238 24 0.023
protein targeting to nucleus GO:0044744 104 0.023
positive regulation of cell differentiation GO:0045597 211 0.023
salivary gland morphogenesis GO:0007435 4 0.023
positive regulation of stress activated mapk cascade GO:0032874 60 0.023
Mouse
t cell selection GO:0045058 4 0.023
neuromuscular junction development GO:0007528 3 0.023
cellular response to molecule of bacterial origin GO:0071219 62 0.023
negative regulation of immune system process GO:0002683 136 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.022
cell morphogenesis GO:0000902 296 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
positive regulation of rig i signaling pathway GO:1900246 4 0.022
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.022
negative regulation of cell cycle GO:0045786 193 0.022
response to inorganic substance GO:0010035 127 0.021
nucleoside catabolic process GO:0009164 408 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
regulation of mononuclear cell proliferation GO:0032944 65 0.021
protein catabolic process GO:0030163 325 0.021
response to bacterium GO:0009617 144 0.021
Zebrafish Fly
regulation of hormone levels GO:0010817 125 0.021
cytoplasmic transport GO:0016482 379 0.021
regulation of intracellular transport GO:0032386 195 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
vasculature development GO:0001944 181 0.021
regulation of leukocyte activation GO:0002694 115 0.021
monocarboxylic acid metabolic process GO:0032787 185 0.021
protein processing GO:0016485 226 0.021
regulation of protein processing GO:0070613 150 0.021
cellular response to nitrogen compound GO:1901699 144 0.021
blastoderm segmentation GO:0007350 2 0.021
blood vessel development GO:0001568 172 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
leukocyte migration GO:0050900 107 0.021
carboxylic acid biosynthetic process GO:0046394 97 0.021
negative regulation of developmental process GO:0051093 247 0.021
ras protein signal transduction GO:0007265 73 0.021
regulation of metal ion transport GO:0010959 120 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
cellular response to external stimulus GO:0071496 111 0.021
photoreceptor cell differentiation GO:0046530 2 0.020
negative regulation of catabolic process GO:0009895 104 0.020
oxidation reduction process GO:0055114 396 0.020
regulation of body fluid levels GO:0050878 99 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
cellular protein catabolic process GO:0044257 261 0.020
regulation of leukocyte differentiation GO:1902105 61 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
regulation of jnk cascade GO:0046328 73 0.020
Mouse
regulation of cell development GO:0060284 161 0.020
t cell activation GO:0042110 99 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.020
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
rhythmic behavior GO:0007622 2 0.020
response to extracellular stimulus GO:0009991 85 0.020
cellular response to biotic stimulus GO:0071216 71 0.020
maintenance of location GO:0051235 112 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
small molecule biosynthetic process GO:0044283 157 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
positive regulation of cellular component movement GO:0051272 181 0.020
regulation of response to biotic stimulus GO:0002831 55 0.020
Fly
regulation of protein maturation GO:1903317 150 0.020
negative regulation of protein processing GO:0010955 142 0.020
cytokine secretion GO:0050663 64 0.020
positive regulation of protein kinase b signaling GO:0051897 42 0.020
response to metal ion GO:0010038 84 0.020
response to fungus GO:0009620 4 0.020
mitotic cell cycle process GO:1903047 286 0.020
positive regulation of leukocyte chemotaxis GO:0002690 38 0.019
epithelium development GO:0060429 227 0.019
response to abiotic stimulus GO:0009628 336 0.019
nucleotide catabolic process GO:0009166 408 0.019
single organism membrane organization GO:0044802 268 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.019
actin filament organization GO:0007015 128 0.019
phospholipid biosynthetic process GO:0008654 44 0.019
neurological system process GO:0050877 163 0.019
negative regulation of transport GO:0051051 176 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
regulation of cellular response to stress GO:0080135 244 0.019
Mouse
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
regulation of ion transmembrane transport GO:0034765 132 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
divalent inorganic cation transport GO:0072511 158 0.019
epithelial cell differentiation GO:0030855 141 0.019
positive regulation of organelle organization GO:0010638 195 0.019
negative regulation of cellular catabolic process GO:0031330 83 0.019
cell matrix adhesion GO:0007160 85 0.018
response to oxygen levels GO:0070482 100 0.018
cranial nerve development GO:0021545 4 0.018
monosaccharide metabolic process GO:0005996 74 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
segmentation GO:0035282 4 0.018
organophosphate catabolic process GO:0046434 430 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
coagulation GO:0050817 78 0.018
myeloid leukocyte migration GO:0097529 62 0.018
protein localization to nucleus GO:0034504 136 0.018
cell projection organization GO:0030030 252 0.018
positive regulation of cell activation GO:0050867 81 0.018
response to lipopolysaccharide GO:0032496 70 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
gtp catabolic process GO:0006184 237 0.018
phosphatidylinositol biosynthetic process GO:0006661 25 0.018
cellular response to lipid GO:0071396 127 0.018
positive regulation of cell cycle process GO:0090068 106 0.018
nitrogen compound transport GO:0071705 191 0.018
regulation of lymphocyte activation GO:0051249 103 0.018
monocarboxylic acid biosynthetic process GO:0072330 67 0.018
positive regulation of t cell activation GO:0050870 54 0.018
cell cell signaling GO:0007267 155 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
cell division GO:0051301 168 0.018
myeloid leukocyte differentiation GO:0002573 60 0.017
angiogenesis GO:0001525 147 0.017
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.017
peripheral nervous system development GO:0007422 2 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.017
Mouse
calcium ion transport GO:0006816 147 0.017
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.017
hemostasis GO:0007599 76 0.017
regulation of cytokine secretion GO:0050707 57 0.017
regulation of lipase activity GO:0060191 37 0.017
cellular response to nutrient levels GO:0031669 69 0.017
oocyte differentiation GO:0009994 2 0.017
response to nutrient levels GO:0031667 81 0.017
actin filament based process GO:0030029 224 0.017
interleukin 2 secretion GO:0070970 3 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
regulation of lipid metabolic process GO:0019216 96 0.017
positive regulation of protein transport GO:0051222 135 0.017
rna interference GO:0016246 4 0.017
inorganic cation transmembrane transport GO:0098662 194 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.016
Mouse
establishment of protein localization to organelle GO:0072594 172 0.016
regulation of growth GO:0040008 165 0.016
cell substrate adhesion GO:0031589 132 0.016
positive regulation of cell size GO:0045793 3 0.016
response to hormone GO:0009725 175 0.016
regulation of cell cycle process GO:0010564 266 0.016
somatic stem cell division GO:0048103 1 0.016
regeneration GO:0031099 4 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
oocyte development GO:0048599 1 0.016
positive regulation of chemotaxis GO:0050921 57 0.016
regulation of calcium ion transport GO:0051924 79 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.016
positive regulation of secretion GO:0051047 116 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
regulation of t cell proliferation GO:0042129 42 0.016
cellular protein complex assembly GO:0043623 188 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
compound eye development GO:0048749 1 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
anion transmembrane transport GO:0098656 76 0.016
positive regulation of defense response GO:0031349 87 0.016
regulation of interferon gamma production GO:0032649 36 0.016
positive regulation of catabolic process GO:0009896 310 0.016
Fly
neurogenesis GO:0022008 169 0.016
jak stat cascade GO:0007259 46 0.016
regulation of membrane potential GO:0042391 95 0.016
ribonucleoside catabolic process GO:0042454 406 0.015
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.015
sensory perception GO:0007600 103 0.015
regulation of actin filament based process GO:0032970 141 0.015
inner ear morphogenesis GO:0042472 4 0.015
blood circulation GO:0008015 113 0.015
dephosphorylation GO:0016311 209 0.015
visual behavior GO:0007632 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
positive regulation of cell adhesion GO:0045785 84 0.015
negative regulation of viral process GO:0048525 66 0.015
regulation of sensory perception GO:0051931 3 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
positive regulation of jnk cascade GO:0046330 52 0.015
Mouse
single organismal cell cell adhesion GO:0016337 148 0.015
blood coagulation GO:0007596 76 0.015
cerebral cortex cell migration GO:0021795 3 0.015
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
regulation of innate immune response GO:0045088 97 0.015
positive regulation of calcium ion transport GO:0051928 51 0.015
positive regulation of interferon beta production GO:0032728 17 0.015
positive regulation of protein secretion GO:0050714 60 0.015
response to decreased oxygen levels GO:0036293 96 0.015
negative regulation of proteolysis GO:0045861 132 0.015
nervous system development GO:0007399 293 0.015
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.015
Mouse
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.014
positive regulation of endothelial cell migration GO:0010595 39 0.014
regulation of erk1 and erk2 cascade GO:0070372 99 0.014
single organism reproductive process GO:0044702 98 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.014
glial cell migration GO:0008347 4 0.014
lipid catabolic process GO:0016042 84 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
jnk cascade GO:0007254 80 0.014
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.014
positive regulation of jak stat cascade GO:0046427 35 0.014
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.014
astrocyte differentiation GO:0048708 4 0.014
platelet activation GO:0030168 44 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
regulation of chemokine production GO:0032642 31 0.014
tissue homeostasis GO:0001894 63 0.014
neuroblast proliferation GO:0007405 4 0.014
regulation of protein kinase b signaling GO:0051896 61 0.014
inositol lipid mediated signaling GO:0048017 55 0.014
regulation of cytokine biosynthetic process GO:0042035 35 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
Fly
positive regulation of homeostatic process GO:0032846 47 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
positive regulation of transmembrane transport GO:0034764 41 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
cellular response to lipopolysaccharide GO:0071222 57 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
lipid modification GO:0030258 84 0.014
stress activated mapk cascade GO:0051403 93 0.014
Mouse
negative regulation of mitotic cell cycle GO:0045930 102 0.014
negative regulation of protein maturation GO:1903318 142 0.014
protein import into nucleus GO:0006606 104 0.014
positive regulation of multi organism process GO:0043902 56 0.014
growth of symbiont in host GO:0044117 1 0.014
lipid transport GO:0006869 90 0.014
inflammatory response GO:0006954 79 0.013
positive regulation of lipase activity GO:0060193 28 0.013
nerve development GO:0021675 4 0.013

TLR3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.043
cancer DOID:162 167 0.035
disease of cellular proliferation DOID:14566 174 0.035
organ system cancer DOID:0050686 164 0.035
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
nervous system disease DOID:863 431 0.022
eye disease DOID:5614 149 0.022
immune system disease DOID:2914 155 0.021
hematopoietic system disease DOID:74 100 0.021
central nervous system disease DOID:331 186 0.020
musculoskeletal system disease DOID:17 223 0.019
gastrointestinal system cancer DOID:3119 52 0.018
inherited metabolic disorder DOID:655 242 0.018
retinal disease DOID:5679 118 0.016
reproductive organ cancer DOID:193 23 0.014