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Homo sapiens

23 genes annotated in human

reproductive organ cancer

DOID:193

An organ system cancer that is manifested in the reproductive organs.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "reproductive organ cancer"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "reproductive organ cancer" (in gray)

Name	Description	Probability	Func Analog Organism
APC	adenomatous polyposis coli	0.323
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.262
IRS1	insulin receptor substrate 1	0.213
BRCA1	breast cancer 1, early onset	0.185
FANCD2	Fanconi anemia, complementation group D2	0.163
ZNF746	zinc finger protein 746	0.154
JUP	junction plakoglobin	0.150	Human
JUN	jun proto-oncogene	0.125
PSEN1	presenilin 1	0.120
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.115
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.114
GSK3B	glycogen synthase kinase 3 beta	0.106
CTNND1	catenin (cadherin-associated protein), delta 1	0.105
STRADA	STE20-related kinase adaptor alpha	0.088
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.086
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.081
KITLG	KIT ligand	0.080
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.072
RB1	retinoblastoma 1	0.072
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.067
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.064
BARD1	BRCA1 associated RING domain 1	0.064
BTRC	beta-transducin repeat containing	0.063
FGFR1	fibroblast growth factor receptor 1	0.058	Human
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.057
DUSP1	dual specificity phosphatase 1	0.057
GLIS2	GLIS family zinc finger 2	0.055
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.048
FGF1	fibroblast growth factor 1 (acidic)	0.048
MSH3	mutS homolog 3 (E. coli)	0.040
TCF4	transcription factor 4	0.039
TP53	tumor protein p53	0.038
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.033
KLF4	Kruppel-like factor 4 (gut)	0.032	Human
PDPK1	3-phosphoinositide dependent protein kinase-1	0.031
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.030
KRT8	keratin 8	0.030
STRADB	STE20-related kinase adaptor beta	0.029
TNIP2	TNFAIP3 interacting protein 2	0.029
NCOA2	nuclear receptor coactivator 2	0.029
MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	0.029
AXIN1	axin 1	0.026
FERMT2	fermitin family member 2	0.022
PALB2	partner and localizer of BRCA2	0.022
DCTN1	dynactin 1	0.022
AR	androgen receptor	0.022
FHL2	four and a half LIM domains 2	0.022
CMIP	c-Maf-inducing protein	0.020
SYK	spleen tyrosine kinase	0.020
FOXO1	forkhead box O1	0.020
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.019
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.019
GAB1	GRB2-associated binding protein 1	0.019
EMD	emerin	0.018
MAD2L1BP	MAD2L1 binding protein	0.017
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.017
CLSPN	claspin	0.017
C5orf41	chromosome 5 open reading frame 41	0.017
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.017
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.017
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.016
ADAM17	ADAM metallopeptidase domain 17	0.016
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.016
PMS1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	0.016
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.015
SMC1A	structural maintenance of chromosomes 1A	0.015
MYST2	MYST histone acetyltransferase 2	0.015
BLM	Bloom syndrome, RecQ helicase-like	0.014
TLR3	toll-like receptor 3	0.014
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.014
MDC1	mediator of DNA-damage checkpoint 1	0.014
CREBBP	CREB binding protein	0.014
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.014
PLEKHA7	pleckstrin homology domain containing, family A member 7	0.013
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.013
AXL	AXL receptor tyrosine kinase	0.013
SYCP3	synaptonemal complex protein 3	0.013
PPL	periplakin	0.013
FGFR2	fibroblast growth factor receptor 2	0.013	Human
ANAPC4	anaphase promoting complex subunit 4	0.013
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.013
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
FOXO3	forkhead box O3	0.012
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.012
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.012
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.012
FOXA1	forkhead box A1	0.012
FANCA	Fanconi anemia, complementation group A	0.012
MAPT	microtubule-associated protein tau	0.012
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.012
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.012
JUND	jun D proto-oncogene	0.012
H2AFX	H2A histone family, member X	0.011
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.011	Human
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.011	Human
BTG1	B-cell translocation gene 1, anti-proliferative	0.011
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.011
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.011
CDK2	cyclin-dependent kinase 2	0.011
PACRG	PARK2 co-regulated	0.011
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
SKP1	S-phase kinase-associated protein 1	0.011
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.011
FBXW11	F-box and WD repeat domain containing 11	0.010
FRMD5	FERM domain containing 5	0.010
PER3	period homolog 3 (Drosophila)	0.010
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.010	Human
EZR	ezrin	0.010
PEBP4	phosphatidylethanolamine-binding protein 4	0.010
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.008
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.007
BRCA2	breast cancer 2, early onset	0.007
PTEN	phosphatase and tensin homolog	0.005
MSMB	microseminoprotein, beta-	0.004
RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	0.004
ZFHX3	zinc finger homeobox 3	0.004
MLH3	mutL homolog 3 (E. coli)	0.004
FGFR3	fibroblast growth factor receptor 3	0.003
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	0.003
MXI1	MAX interactor 1	0.003
EHBP1	EH domain binding protein 1	0.003
OPCML	opioid binding protein/cell adhesion molecule-like	0.002
MSR1	macrophage scavenger receptor 1	0.002
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.002
STK11	serine/threonine kinase 11	0.002
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.002
KLF6	Kruppel-like factor 6	0.001
MSH6	mutS homolog 6 (E. coli)	0.000