IMP

Process View

Homo sapiens

25 genes annotated in human

phosphatidylinositol biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "phosphatidylinositol biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "phosphatidylinositol biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.960	Rat
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.811
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.623
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.486
GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	0.483	Yeast
FGFR2	fibroblast growth factor receptor 2	0.469
FGFR1	fibroblast growth factor receptor 1	0.381
NOS1	nitric oxide synthase 1 (neuronal)	0.297
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.266
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.207
IRS1	insulin receptor substrate 1	0.187
PLCG1	phospholipase C, gamma 1	0.183	Human
PIGT	phosphatidylinositol glycan anchor biosynthesis, class T	0.181	Yeast
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.163
CMIP	c-Maf-inducing protein	0.130
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.101
NRP1	neuropilin 1	0.067
FGF10	fibroblast growth factor 10	0.062	Human
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.059
CD9	CD9 molecule	0.056	Human
SPAG9	sperm associated antigen 9	0.051
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.047
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.047
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.045
POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	0.044
CD81	CD81 molecule	0.044
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.037
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.035
CD63	CD63 molecule	0.034
SYK	spleen tyrosine kinase	0.033
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.031
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.030
GAB1	GRB2-associated binding protein 1	0.030
PIKFYVE	phosphoinositide kinase, FYVE finger containing	0.029
TSPAN4	tetraspanin 4	0.028
PTPRB	protein tyrosine phosphatase, receptor type, B	0.027
BLNK	B-cell linker	0.024
HSPG2	heparan sulfate proteoglycan 2	0.024
SORBS1	sorbin and SH3 domain containing 1	0.023
THBS1	thrombospondin 1	0.022
ATMIN	ATM interactor	0.022
NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	0.022
PDGFA	platelet-derived growth factor alpha polypeptide	0.022
LAT	linker for activation of T cells	0.022
FGF2	fibroblast growth factor 2 (basic)	0.022
PDGFC	platelet derived growth factor C	0.022
FGF1	fibroblast growth factor 1 (acidic)	0.021	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.021
GRB7	growth factor receptor-bound protein 7	0.020
VAV2	vav 2 guanine nucleotide exchange factor	0.020
VAV3	vav 3 guanine nucleotide exchange factor	0.019
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.019
FGF7	fibroblast growth factor 7	0.019	Human
GAB2	GRB2-associated binding protein 2	0.019
UVRAG	UV radiation resistance associated gene	0.019
PIGS	phosphatidylinositol glycan anchor biosynthesis, class S	0.019	Yeast
COL6A1	collagen, type VI, alpha 1	0.018
TLR3	toll-like receptor 3	0.018
SCAND1	SCAN domain containing 1	0.018
DLG5	discs, large homolog 5 (Drosophila)	0.018
CUTA	cutA divalent cation tolerance homolog (E. coli)	0.018
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.017
IPO11	importin 11	0.017
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.017
C1D	C1D nuclear receptor corepressor	0.016
HPS6	Hermansky-Pudlak syndrome 6	0.016
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.016
AXL	AXL receptor tyrosine kinase	0.016
CHMP2B	chromatin modifying protein 2B	0.016
ALAS1	aminolevulinate, delta-, synthase 1	0.016
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.016
GSS	glutathione synthetase	0.015
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.015
SH3KBP1	SH3-domain kinase binding protein 1	0.015
SEP15	15 kDa selenoprotein	0.014
FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	0.014	Yeast
FRS2	fibroblast growth factor receptor substrate 2	0.014
DSCAML1	Down syndrome cell adhesion molecule like 1	0.014
PFDN4	prefoldin subunit 4	0.014
PTK6	PTK6 protein tyrosine kinase 6	0.014
BAI1	brain-specific angiogenesis inhibitor 1	0.014
ARRDC3	arrestin domain containing 3	0.013
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.013	Mouse Rat
INSR	insulin receptor	0.013
PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4	0.013
SORBS3	sorbin and SH3 domain containing 3	0.012
USP16	ubiquitin specific peptidase 16	0.012
INO80B	INO80 complex subunit B	0.012
C1orf9	chromosome 1 open reading frame 9	0.012
COL5A1	collagen, type V, alpha 1	0.012
SLMO2	slowmo homolog 2 (Drosophila)	0.012
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.012
NOSTRIN	nitric oxide synthase trafficker	0.012
G6PC3	glucose 6 phosphatase, catalytic, 3	0.012
CD99	CD99 molecule	0.012
NME3	non-metastatic cells 3, protein expressed in	0.012
BCAS2	breast carcinoma amplified sequence 2	0.012
ERRFI1	ERBB receptor feedback inhibitor 1	0.012
CD28	CD28 molecule	0.012
SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)	0.011
GMFB	glia maturation factor, beta	0.011
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.011
SH3BP2	SH3-domain binding protein 2	0.011
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.011
SOS2	son of sevenless homolog 2 (Drosophila)	0.011
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.011
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.011	Human Fly
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.011
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.010
VEGFA	vascular endothelial growth factor A	0.010	Human
PIGU	phosphatidylinositol glycan anchor biosynthesis, class U	0.010
HSPA13	heat shock protein 70kDa family, member 13	0.010
TP53BP1	tumor protein p53 binding protein 1	0.010
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.010
CHID1	chitinase domain containing 1	0.010
GOLT1B	golgi transport 1B	0.010
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.010
COL2A1	collagen, type II, alpha 1	0.010