|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
1.000
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
1.000
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
1.000
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
protein neddylation
|
GO:0045116 |
7 |
1.000
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.999
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.998
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.998
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.998
|
Yeast Worm Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.998
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.997
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.995
|
Yeast Worm Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.995
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.991
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.986
|
Fly |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.979
|
|
|
|
cyclin catabolic process
|
GO:0008054 |
6 |
0.974
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.971
|
Worm Fly |
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.966
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.966
|
Yeast Fly |
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.960
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.958
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.952
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.946
|
Fly |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.937
|
Worm Fly |
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.933
|
Mouse |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.920
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.907
|
Fly |
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.905
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.893
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.881
|
|
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
0.879
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.872
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.870
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.845
|
Yeast Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.844
|
Worm Fly |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.839
|
Fly |
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.835
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.830
|
Fly |
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.824
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.823
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.814
|
Worm |
|
|
nuclear division
|
GO:0000280 |
128 |
0.807
|
Worm |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.804
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.800
|
Fly |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.795
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.795
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.780
|
Worm |
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.768
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.741
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.722
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.710
|
Worm |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.707
|
Worm |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.686
|
Yeast |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.681
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.674
|
Fly |
|
|
behavior
|
GO:0007610 |
112 |
0.655
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.655
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.647
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.647
|
|
|
|
regulation of centrosome duplication
|
GO:0010824 |
14 |
0.637
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.620
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.597
|
Worm |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.593
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.587
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.571
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.563
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.553
|
Worm |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.552
|
Yeast |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.542
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.531
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.530
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.526
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.518
|
Yeast |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.503
|
Fly |
|
|
centrosome organization
|
GO:0051297 |
58 |
0.498
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.492
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.489
|
Fly |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.486
|
Fly |
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.485
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.482
|
Fly |
|
|
cullin deneddylation
|
GO:0010388 |
9 |
0.478
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.476
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.463
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.454
|
Fly |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.454
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.440
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.437
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.433
|
Fly |
|
|
kinetochore organization
|
GO:0051383 |
8 |
0.429
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.426
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.423
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.420
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.415
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.411
|
Worm Fly |
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.407
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.401
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.395
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.380
|
|
|
|
centromere complex assembly
|
GO:0034508 |
10 |
0.376
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.366
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.364
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.351
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.344
|
Worm |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.342
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.325
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.323
|
Fly |
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.321
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.319
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.319
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.310
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.308
|
Worm Fly |
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.305
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.303
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.300
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.297
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.293
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.287
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.286
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.282
|
Worm |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.282
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.280
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.280
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.279
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.278
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.277
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.272
|
Fly |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.266
|
Worm |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.259
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.258
|
Yeast |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.255
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.253
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.252
|
Worm Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.251
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.248
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.246
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.245
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.242
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.237
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.236
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.235
|
Worm |
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.233
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.233
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.230
|
Worm |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.227
|
Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.224
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.224
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.219
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.219
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.217
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.212
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.212
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.210
|
Fly |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.207
|
Fly |
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.206
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.200
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.199
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.198
|
Fly |
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.197
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.196
|
Worm |
|
|
response to insulin
|
GO:0032868 |
45 |
0.194
|
Fly |
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.194
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.193
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.192
|
Worm |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.191
|
Fly |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.188
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.186
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.185
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.185
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.180
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.180
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.176
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.176
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.173
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.164
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.163
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.162
|
Worm |
|
|
positive regulation of metaphase anaphase transition of cell cycle
|
GO:1902101 |
6 |
0.162
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.157
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.156
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
16 |
0.155
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.153
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.152
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.152
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.152
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.147
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.147
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.145
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.144
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.144
|
Yeast |
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.144
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.143
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.142
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.140
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.139
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.139
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.139
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.138
|
Worm |
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.137
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.136
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.136
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.134
|
Worm |
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
6 |
0.129
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.128
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.128
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.128
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.128
|
|
|
|
negative regulation of posttranscriptional gene silencing
|
GO:0060149 |
3 |
0.126
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.126
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.125
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.124
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.121
|
|
|
|
regulation of cellular ph
|
GO:0030641 |
17 |
0.120
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.120
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.119
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.119
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.119
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.118
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.118
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.117
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.116
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.116
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.115
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.115
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.115
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.114
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.114
|
|
|
|
vesicle targeting rough er to cis golgi
|
GO:0048207 |
2 |
0.113
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.110
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.108
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.107
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.107
|
Worm |
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.106
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.103
|
Mouse |
|
|
kinetochore assembly
|
GO:0051382 |
8 |
0.102
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.100
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.098
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.098
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.097
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.097
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.096
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.096
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.095
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.094
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.093
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.093
|
Fly |
|
|
developmental maturation
|
GO:0021700 |
28 |
0.093
|
Fly |
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.091
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.091
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.090
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.089
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.089
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.089
|
|
|
|
neuron maturation
|
GO:0042551 |
5 |
0.088
|
Fly |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.086
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.085
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.085
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.085
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.085
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.084
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.083
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.082
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.081
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
62 |
0.081
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.081
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.081
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.081
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.080
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.079
|
|
|
|
regulation of rna stability
|
GO:0043487 |
23 |
0.077
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.077
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.075
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.075
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.074
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.073
|
Worm |
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.073
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.073
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.073
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.071
|
Fly |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.071
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.071
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.070
|
|
|
|
copii vesicle coating
|
GO:0048208 |
2 |
0.070
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.070
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.069
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.069
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.068
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.067
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.067
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.066
|
Worm |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.066
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.066
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.064
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.063
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.063
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.063
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.061
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.061
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.061
|
Worm |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.061
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.060
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.059
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.059
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.058
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.058
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.057
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.057
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.057
|
Fly |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.055
|
Fly |
|
|
embryonic axis specification
|
GO:0000578 |
5 |
0.055
|
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.055
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.055
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.055
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.054
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.054
|
Worm |
|
|
response to radiation
|
GO:0009314 |
151 |
0.053
|
|
|
|
aging
|
GO:0007568 |
66 |
0.053
|
Worm |
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.052
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.052
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.051
|
|
|
|
rrna processing
|
GO:0006364 |
35 |
0.051
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.051
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.051
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.050
|
|
|
|
positive regulation of circadian rhythm
|
GO:0042753 |
1 |
0.050
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.049
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.049
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.049
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.049
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.049
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.048
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.048
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.048
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.048
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.047
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.047
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.047
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.047
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.046
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.046
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.046
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.045
|
|
|
|
centriole replication
|
GO:0007099 |
13 |
0.045
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.045
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.045
|
|
|
|
cellular hyperosmotic response
|
GO:0071474 |
4 |
0.044
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.044
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.044
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.044
|
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.043
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.043
|
Worm |
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.043
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.043
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.043
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.043
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.042
|
Worm |
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.042
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.042
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.042
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.041
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.040
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.040
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.040
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.039
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.039
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.039
|
Worm |
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.038
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.037
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.037
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.037
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
8 |
0.036
|
Fly |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.036
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.036
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.036
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.036
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.036
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.036
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.036
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.035
|
|
|
|
system process
|
GO:0003008 |
349 |
0.035
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.035
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.035
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.035
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.034
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.034
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.034
|
Worm |
|
|
srebp signaling pathway
|
GO:0032933 |
4 |
0.033
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.033
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.033
|
Worm |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.033
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.032
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.032
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.032
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.032
|
|
|
|
ribosome biogenesis
|
GO:0042254 |
48 |
0.031
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.031
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.031
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.031
|
Fly |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.031
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.031
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.031
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.031
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.031
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.031
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.031
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.031
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.030
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.030
|
|
|
|
maturation of lsu rrna
|
GO:0000470 |
3 |
0.030
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.029
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.029
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.029
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.029
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.029
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.029
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.029
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.029
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.029
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.028
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.028
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.027
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.027
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.027
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.027
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.027
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.027
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.027
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.026
|
Worm |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.026
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.026
|
Worm Fly |
|
|
translation
|
GO:0006412 |
132 |
0.026
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.026
|
Fly |
|
|
regulation of lipid storage
|
GO:0010883 |
21 |
0.025
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.025
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.025
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.025
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
12 |
0.025
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.025
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.025
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.025
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.024
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.024
|
|
|
|
regulation of ph
|
GO:0006885 |
20 |
0.024
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.023
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.023
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.023
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.023
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.023
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.023
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.023
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.022
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.022
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.022
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.022
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
8 |
0.022
|
Fly |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.022
|
|
|
|
memory
|
GO:0007613 |
3 |
0.022
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.022
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.022
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.022
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.021
|
|
|
|
endoplasmic reticulum organization
|
GO:0007029 |
20 |
0.021
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.021
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.021
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.021
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.021
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.021
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.021
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.021
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.020
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.020
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.020
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.020
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.019
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.019
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.019
|
Worm |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.019
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.019
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.019
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.019
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.019
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.019
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.018
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.018
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.018
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.018
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.018
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.018
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.018
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.018
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.018
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.018
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.018
|
|
|
|
negative regulation of nf kappab import into nucleus
|
GO:0042347 |
12 |
0.018
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.017
|
|
|
|
cellular response to sterol depletion
|
GO:0071501 |
4 |
0.017
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.017
|
|
