IMP
Process View
scf dependent proteasomal ubiquitin dependent protein catabolic process
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "scf dependent proteasomal ubiquitin dependent protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CUL1 | cullin 1 | 1.000 | ||
| SKP1 | S-phase kinase-associated protein 1 | 1.000 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 1.000 | ||
| BTRC | beta-transducin repeat containing | 1.000 | Human | |
| FBXW2 | F-box and WD repeat domain containing 2 | 0.999 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.993 | ||
| YY1 | YY1 transcription factor | 0.976 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.971 | ||
| FBXO33 | F-box protein 33 | 0.964 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.795 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.733 | ||
| FBXO25 | F-box protein 25 | 0.547 | ||
| FBXO4 | F-box protein 4 | 0.528 | ||
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.507 | ||
| FBXO3 | F-box protein 3 | 0.491 | ||
| FBXW5 | F-box and WD repeat domain containing 5 | 0.234 | ||
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.179 | ||
| ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.157 | ||
| INO80 | INO80 homolog (S. cerevisiae) | 0.135 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.129 | ||
| FBXO34 | F-box protein 34 | 0.127 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.110 | ||
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.104 | ||
| CP110 | CP110 protein | 0.101 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.080 | ||
| FBXW9 | F-box and WD repeat domain containing 9 | 0.060 | ||
| E2F6 | E2F transcription factor 6 | 0.060 | ||
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | 0.052 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.050 | ||
| KDM2B | lysine (K)-specific demethylase 2B | 0.043 | ||
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.032 | ||
| FBXO7 | F-box protein 7 | 0.031 | ||
| ECD | ecdysoneless homolog (Drosophila) | 0.030 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.030 | ||
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.028 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.028 | ||
| FBXO44 | F-box protein 44 | 0.026 | Human | |
| RNF32 | ring finger protein 32 | 0.024 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.023 | ||
| ING2 | inhibitor of growth family, member 2 | 0.023 | ||
| UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.022 | ||
| NEURL4 | neuralized homolog 4 (Drosophila) | 0.022 | ||
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.021 | ||
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.018 | ||
| YBX1 | Y box binding protein 1 | 0.018 | ||
| FBXL3 | F-box and leucine-rich repeat protein 3 | 0.016 | ||
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.015 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.015 | ||
| RYBP | RING1 and YY1 binding protein | 0.015 | Fly | |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.014 | ||
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.013 | ||
| FBXO18 | F-box protein, helicase, 18 | 0.012 | ||
| RNF11 | ring finger protein 11 | 0.011 | ||
| ARRB1 | arrestin, beta 1 | 0.011 | ||
| FBXO6 | F-box protein 6 | 0.011 | ||
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.011 | ||
| SMAD1 | SMAD family member 1 | 0.011 | ||
| TRAIP | TRAF interacting protein | 0.010 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.010 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.010 | ||
| SMAD7 | SMAD family member 7 | 0.010 | ||
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.010 |