|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.389
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.358
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.350
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.335
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.282
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.227
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.220
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.211
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.208
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.200
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.198
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.197
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.194
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.193
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.180
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.177
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.169
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.164
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.163
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.154
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.152
|
Mouse |
|
|
oocyte development
|
GO:0048599 |
1 |
0.151
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.151
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.150
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.150
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.150
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.147
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.147
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.146
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.146
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.143
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.141
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.140
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.138
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.138
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.137
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.135
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.134
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.130
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.130
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.128
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.127
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.127
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.126
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.123
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.123
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.121
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.120
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.120
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.119
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.119
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.118
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.115
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.114
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.114
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.113
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.111
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.111
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.109
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.108
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.106
|
Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.104
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.103
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.102
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.101
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.101
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.101
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.099
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.098
|
Mouse |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.097
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.097
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.096
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.096
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.096
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.095
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.095
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.095
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.095
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.093
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.093
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.093
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.091
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.091
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.090
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.089
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.088
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.088
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.088
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.086
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.085
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.084
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.083
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.083
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.083
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.083
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.082
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.082
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.081
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.081
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.079
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.079
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.079
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.078
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.077
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.077
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.077
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.077
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.077
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.076
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.076
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.075
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.074
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.074
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.074
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.074
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.074
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.073
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.072
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.072
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.072
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.071
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.071
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.070
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.070
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.070
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.069
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.069
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.069
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.067
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.067
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.067
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.067
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.067
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.067
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.067
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.067
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.066
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.066
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.065
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.064
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.064
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.064
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.064
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.063
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.063
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.063
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.063
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.062
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.062
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.062
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.061
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.061
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.060
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.059
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.059
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.059
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.059
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
3 |
0.058
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.058
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.058
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.057
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.057
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.056
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.056
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.056
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.055
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.055
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.055
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.055
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.055
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.055
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.054
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.054
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.054
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.054
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.054
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.053
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.053
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.053
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.053
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.053
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.050
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.050
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.050
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.050
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.049
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.049
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.049
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.049
|
Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.049
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.049
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.049
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.049
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.048
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.048
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.048
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.048
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.047
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.047
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.047
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.047
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.047
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.047
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.047
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.046
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.046
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.046
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.046
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.045
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.045
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.045
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.045
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.045
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.044
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.044
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.044
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.044
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.044
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.044
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.044
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.044
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.043
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.043
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.043
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.043
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.043
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.043
|
Mouse |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.042
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.042
|
|
|
|
endosome to lysosome transport
|
GO:0008333 |
21 |
0.042
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.042
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.042
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.042
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.042
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.041
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.041
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.041
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.041
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.041
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.041
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.040
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.040
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.040
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.040
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.039
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.039
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.039
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.039
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.039
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.039
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.039
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.038
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.038
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.038
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.038
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.038
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.038
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.037
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.037
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.037
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.036
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.036
|
Mouse |
|
|
protein import
|
GO:0017038 |
130 |
0.036
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
4 |
0.036
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.036
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.035
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.035
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.035
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.035
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.035
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.035
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.034
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.034
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.034
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.034
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.034
|
Mouse |
|
|
reproductive process
|
GO:0022414 |
106 |
0.034
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.033
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.033
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.033
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.033
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.033
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.032
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.032
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.032
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.032
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.032
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.032
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.032
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.032
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.031
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.031
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.031
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.031
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.031
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.031
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.031
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.031
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.031
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.031
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.031
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.030
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.030
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.030
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.030
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.030
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.030
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.030
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.030
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.030
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.030
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.030
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.030
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.030
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.029
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.029
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.029
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.029
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.029
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.029
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.029
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.028
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.028
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.028
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.028
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.028
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.028
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.028
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.028
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.027
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.027
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.027
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.027
|
|
|
|
head development
|
GO:0060322 |
108 |
0.027
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.027
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.027
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.027
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.027
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.027
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.026
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.026
|
|
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.026
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.026
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.026
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.026
|
|
|
|
memory
|
GO:0007613 |
3 |
0.026
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.026
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.026
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.026
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.026
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.026
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.025
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.025
|
|
|
|
aging
|
GO:0007568 |
66 |
0.025
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.025
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.025
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.025
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.025
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.025
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.025
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.025
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.024
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.024
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.024
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.024
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.024
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.024
|
Mouse |
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.024
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.024
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.024
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.024
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.024
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.024
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.024
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.024
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.024
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.024
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.024
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.023
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.023
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.023
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.023
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.023
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.023
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.023
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.023
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.023
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.023
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.023
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.022
|
|
|
|
trna processing
|
GO:0008033 |
23 |
0.022
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.022
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.022
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.022
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
2 |
0.022
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.022
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.022
|
|
|
|
cell cell recognition
|
GO:0009988 |
4 |
0.022
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.022
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.022
|
|
|
|
hair cycle phase
|
GO:0044851 |
3 |
0.022
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.022
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.021
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.021
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.021
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.021
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.021
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.021
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.021
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.021
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.021
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.021
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.021
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.021
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.021
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.021
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.020
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.020
|
Mouse |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.020
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.020
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.020
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.020
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.020
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.020
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.020
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.020
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.020
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.020
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.020
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.020
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.020
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.020
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.020
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.020
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.020
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.020
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.020
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.020
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.020
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.020
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.020
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.019
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.019
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.019
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.019
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.019
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.019
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.019
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.019
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.019
|
Mouse |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.019
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.019
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.019
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.019
|
|
|
|
hair follicle maturation
|
GO:0048820 |
3 |
0.019
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.019
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.018
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.018
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.018
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.018
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.018
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.018
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.018
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.018
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.018
|
|