|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.999
|
Human |
|
|
cell matrix adhesion involved in ameboidal cell migration
|
GO:0003366 |
2 |
0.998
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.996
|
Rat |
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.992
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.991
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.991
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.990
|
|
|
|
response to prostaglandin e
|
GO:0034695 |
6 |
0.989
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.989
|
Human Rat Worm |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.987
|
Rat Worm |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.985
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.985
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.982
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.979
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.978
|
Human Rat |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.972
|
Human Zebrafish |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.971
|
Human Zebrafish |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.969
|
Human |
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.967
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.966
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.966
|
Human Zebrafish Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.959
|
Rat |
|
|
venous blood vessel morphogenesis
|
GO:0048845 |
1 |
0.958
|
|
|
|
venous blood vessel development
|
GO:0060841 |
2 |
0.956
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.948
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.948
|
Human |
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.946
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.940
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.939
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.938
|
Human Zebrafish |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.936
|
Human Zebrafish |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.935
|
Human Zebrafish Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.933
|
Rat |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.930
|
Human Zebrafish |
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.920
|
Human |
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.920
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.913
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.908
|
Human Rat |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.901
|
Rat |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.898
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.897
|
Human Rat |
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.895
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.893
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.891
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.888
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.880
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.878
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.876
|
Human Zebrafish Fly |
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.874
|
Zebrafish |
|
|
response to prostaglandin
|
GO:0034694 |
8 |
0.870
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.869
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.867
|
Human |
|
|
angiogenesis involved in wound healing
|
GO:0060055 |
4 |
0.862
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.860
|
Fly |
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.852
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.847
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.846
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.842
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.840
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.837
|
Zebrafish |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.833
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.826
|
Human Zebrafish |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.825
|
Human |
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.820
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.817
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.815
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.811
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.810
|
|
|
|
calcium independent cell matrix adhesion
|
GO:0007161 |
1 |
0.810
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.807
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.804
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.784
|
Zebrafish |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.776
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.776
|
Mouse |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.775
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
3 |
0.774
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.771
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.770
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.767
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.757
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.757
|
Human |
|
|
pericardium development
|
GO:0060039 |
2 |
0.749
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.738
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.738
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.736
|
Fly |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.735
|
Zebrafish Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.733
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.733
|
Human Worm |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.731
|
Zebrafish Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.726
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.720
|
Human Zebrafish Fly |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.720
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.715
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.712
|
Fly |
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.710
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.708
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.704
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.683
|
Human Zebrafish Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.681
|
Fly |
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.679
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.678
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.676
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.675
|
Worm |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.671
|
Zebrafish Fly |
|
|
positive regulation of cardioblast differentiation
|
GO:0051891 |
2 |
0.671
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.669
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.655
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.651
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.651
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.646
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.645
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.644
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.643
|
Fly |
|
|
nerve development
|
GO:0021675 |
4 |
0.640
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.637
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.611
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.601
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.600
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.599
|
Human |
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.597
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.596
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.589
|
Zebrafish |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.583
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.573
|
Fly |
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.568
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.558
|
Human |
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.555
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.552
|
|
|
|
negative regulation of smooth muscle cell migration
|
GO:0014912 |
7 |
0.547
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.543
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.536
|
Mouse |
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.529
|
Fly |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.523
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.519
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.513
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.513
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.512
|
|
|
|
kinin cascade
|
GO:0002254 |
1 |
0.506
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.505
|
Worm Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.504
|
Human |
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.499
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.498
|
Worm |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.479
|
Human |
|
|
positive regulation of systemic arterial blood pressure
|
GO:0003084 |
2 |
0.477
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.476
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.475
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.471
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.466
|
Zebrafish Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.466
|
Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.464
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.460
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.459
|
Fly |
|
|
establishment of blood brain barrier
|
GO:0060856 |
1 |
0.454
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.447
|
Human |
|
|
positive regulation of plasminogen activation
|
GO:0010756 |
3 |
0.447
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.445
|
|
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.444
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.439
|
Human Worm |
|
|
taxis
|
GO:0042330 |
157 |
0.436
|
Human Fly |
|
|
plasminogen activation
|
GO:0031639 |
11 |
0.436
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.436
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.428
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.422
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.421
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.416
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.416
|
Rat |
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.414
|
Human Mouse |
|
|
positive regulation of fibrinolysis
|
GO:0051919 |
4 |
0.413
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.412
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.410
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.404
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.400
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.397
|
Human |
|
|
endocardium development
|
GO:0003157 |
2 |
0.397
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.395
|
Human |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.388
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.387
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.386
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.384
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.370
|
Human |
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.365
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.359
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.356
|
Fly |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.352
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.352
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.350
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.339
|
Fly |
|
|
stem cell development
|
GO:0048864 |
69 |
0.326
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.323
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.322
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.321
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.321
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.320
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.320
|
|
|
|
regulation of lipoprotein metabolic process
|
GO:0050746 |
7 |
0.320
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.320
|
Human Zebrafish Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.319
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.318
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.317
|
Human Worm |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.312
|
Human Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.311
|
Human |
|
|
positive regulation of hair follicle maturation
|
GO:0048818 |
2 |
0.309
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.308
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.305
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.305
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.304
|
Human |
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.303
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.302
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.298
|
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.297
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.296
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.293
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.290
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.289
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.288
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.288
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.286
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.285
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.283
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.282
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.281
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.280
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.280
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.280
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.278
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.277
|
Human |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.273
|
|
|
|
vascular wound healing
|
GO:0061042 |
4 |
0.268
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.267
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.263
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.262
|
Worm |
|
|
response to hormone
|
GO:0009725 |
175 |
0.260
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.260
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.260
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.258
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.258
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.257
|
|
|
|
integrin activation
|
GO:0033622 |
8 |
0.257
|
|
|
|
chronological cell aging
|
GO:0001300 |
2 |
0.252
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
12 |
0.251
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.250
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.247
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.244
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.241
|
Human Fly |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.241
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.238
|
Zebrafish Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.235
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.235
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.235
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.232
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.231
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.229
|
Fly |
|
|
leukotriene production involved in inflammatory response
|
GO:0002540 |
1 |
0.228
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.224
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.222
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.221
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.221
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.219
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.219
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.218
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.214
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.211
|
Human |
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.211
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.210
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.208
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.207
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.206
|
|
|
|
negative regulation of plasminogen activation
|
GO:0010757 |
4 |
0.203
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.202
|
Human Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.201
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.201
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.201
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.200
|
|
|
|
response to gonadotropin
|
GO:0034698 |
5 |
0.199
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.193
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.192
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.190
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.190
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.189
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.186
|
Fly |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.185
|
Worm |
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.180
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.179
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.179
|
Fly |
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.179
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.179
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.177
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.176
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.175
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.175
|
Zebrafish |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.174
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.174
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.174
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.173
|
Fly |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.173
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.172
|
|
|
|
regulation of fibrinolysis
|
GO:0051917 |
8 |
0.168
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.168
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.165
|
Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.164
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.164
|
Fly |
|
|
positive regulation of blood coagulation
|
GO:0030194 |
11 |
0.161
|
|
|
|
negative regulation of skeletal muscle tissue development
|
GO:0048642 |
2 |
0.161
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.160
|
Fly |
|
|
muscle system process
|
GO:0003012 |
81 |
0.160
|
Worm |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.160
|
Zebrafish |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.159
|
|
|
|
system process
|
GO:0003008 |
349 |
0.159
|
Human Mouse Worm Fly |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.159
|
Human |
|
|
axon development
|
GO:0061564 |
34 |
0.159
|
Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.158
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.158
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.157
|
Human |
|
|
cell aging
|
GO:0007569 |
52 |
0.156
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
55 |
0.156
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.156
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.154
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.152
|
Fly |
|
|
response to ketone
|
GO:1901654 |
19 |
0.152
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.149
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.149
|
|
|
|
regulation of collagen catabolic process
|
GO:0010710 |
3 |
0.149
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.147
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.144
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.141
|
Human |
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.141
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.139
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.139
|
|
|
|
extracellular matrix disassembly
|
GO:0022617 |
16 |
0.137
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.137
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.136
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.134
|
|
|
|
regulation of protein homodimerization activity
|
GO:0043496 |
9 |
0.134
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.134
|
|
|
|
response to luteinizing hormone
|
GO:0034699 |
1 |
0.134
|
|
|
|
collagen catabolic process
|
GO:0030574 |
10 |
0.133
|
|
|
|
response to bmp
|
GO:0071772 |
8 |
0.133
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.131
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.131
|
Human |
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.131
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.127
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.125
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.124
|
Human |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.124
|
Human Worm |
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.123
|
Fly |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.121
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.121
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.121
|
Fly |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.120
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.119
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.119
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.119
|
|
|
|
growth
|
GO:0040007 |
202 |
0.119
|
Human |
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.119
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.118
|
|
|
|
negative regulation of nitric oxide synthase activity
|
GO:0051001 |
3 |
0.117
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.117
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.116
|
Human |
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.115
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
1 |
0.115
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.115
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.112
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.112
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.111
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.111
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.110
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.110
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.110
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.110
|
|
|
|
positive regulation of mesonephros development
|
GO:0061213 |
2 |
0.110
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.110
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.109
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.107
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.107
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.106
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.105
|
Rat |
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.104
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.104
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.104
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.103
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.103
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.102
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.102
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.101
|
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
6 |
0.100
|
|
|
|
collagen biosynthetic process
|
GO:0032964 |
15 |
0.099
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
6 |
0.098
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.098
|
|
|
|
negative regulation of macrophage cytokine production
|
GO:0010936 |
3 |
0.096
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.095
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.093
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.093
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.092
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.092
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.092
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.092
|
Fly |
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.092
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
8 |
0.091
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.089
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.089
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.089
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.089
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.088
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.087
|
|
|
|
artery morphogenesis
|
GO:0048844 |
7 |
0.087
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.087
|
Human |
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.086
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.086
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.086
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.086
|
Fly |
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.086
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.086
|
|
|
|
vasculogenesis
|
GO:0001570 |
8 |
0.086
|
|
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
3 |
0.085
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.085
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.084
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.084
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.084
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.083
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.083
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.083
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
11 |
0.083
|
|
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
1 |
0.082
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.082
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.081
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.081
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.081
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.081
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.080
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.080
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
9 |
0.079
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.079
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.079
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
1 |
0.079
|
Worm |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.079
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.078
|
Mouse Worm |
|
|
negative regulation of alkaline phosphatase activity
|
GO:0010693 |
2 |
0.078
|
|
|
|
cell cell adhesion mediated by integrin
|
GO:0033631 |
8 |
0.078
|
Mouse |
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.078
|
|
|
|
cellular response to vitamin d
|
GO:0071305 |
5 |
0.078
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.078
|
Human |
|
|
gastrulation
|
GO:0007369 |
51 |
0.077
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.077
|
|
|
|
fibrinolysis
|
GO:0042730 |
11 |
0.076
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.076
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.075
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.075
|
|
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.074
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.074
|
|
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.074
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.074
|
Fly |
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.072
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.072
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.071
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.071
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.071
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
11 |
0.070
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.070
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.070
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.070
|
Fly |
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.070
|
|
|
|
negative regulation of low density lipoprotein particle receptor biosynthetic process
|
GO:0045715 |
3 |
0.070
|
Human |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.070
|
Human |
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.069
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.069
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.069
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.069
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.069
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.069
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.068
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.068
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.068
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.067
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.067
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.067
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.066
|
|
|
|
positive regulation of striated muscle contraction
|
GO:0045989 |
1 |
0.066
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.065
|
Zebrafish |
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.065
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.065
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.065
|
Human |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.064
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.064
|
|
|
|
cellular response to vitamin
|
GO:0071295 |
6 |
0.064
|
|
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.064
|
|
|
|
regulation of fibroblast migration
|
GO:0010762 |
7 |
0.063
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.063
|
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.063
|
|
|
|
programmed cell death in response to reactive oxygen species
|
GO:0097468 |
4 |
0.063
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.063
|
|
