IMP

Process View

Homo sapiens

11 genes annotated in human

Multi-species View

positive regulation of blood coagulation

GO:0030194

Any process that activates or increases the frequency, rate or extent of blood coagulation.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of blood coagulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of blood coagulation" (in gray)

Name	Description	Probability	Func Analog Organism
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	1.000
PLAU	plasminogen activator, urokinase	1.000	Human
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.987
PLAUR	plasminogen activator, urokinase receptor	0.750
ALB	albumin	0.628
PLAT	plasminogen activator, tissue	0.514	Human
LY96	lymphocyte antigen 96	0.497
PLG	plasminogen	0.412
FGB	fibrinogen beta chain	0.325
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.299
KEAP1	kelch-like ECH-associated protein 1	0.299
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.243
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.231
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.226
ORM1	orosomucoid 1	0.226
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.223
TICAM2	toll-like receptor adaptor molecule 2	0.179
FGA	fibrinogen alpha chain	0.175
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.174
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.161
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.154
KNG1	kininogen 1	0.141
CTNND1	catenin (cadherin-associated protein), delta 1	0.134
INSR	insulin receptor	0.128
MYD88	myeloid differentiation primary response gene (88)	0.109
LPA	lipoprotein, Lp(a)	0.108	Human
VTN	vitronectin	0.095
C1R	complement component 1, r subcomponent	0.085
C1S	complement component 1, s subcomponent	0.081
MASP2	mannan-binding lectin serine peptidase 2	0.065
C8A	complement component 8, alpha polypeptide	0.060
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.053
C8B	complement component 8, beta polypeptide	0.049
CD320	CD320 molecule	0.048
CHRD	chordin	0.047
BAD	BCL2-associated agonist of cell death	0.046
AHSG	alpha-2-HS-glycoprotein	0.039
HPX	hemopexin	0.039
F13A1	coagulation factor XIII, A1 polypeptide	0.037
F11	coagulation factor XI	0.037
F10	coagulation factor X	0.036	Human
HRG	histidine-rich glycoprotein	0.034	Mouse
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.034
PRODH2	proline dehydrogenase (oxidase) 2	0.032
CPN1	carboxypeptidase N, polypeptide 1	0.027
INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	0.026
THBS1	thrombospondin 1	0.026
FRMD5	FERM domain containing 5	0.026
CD93	CD93 molecule	0.024
FGG	fibrinogen gamma chain	0.024
VCAN	versican	0.024
COL4A1	collagen, type IV, alpha 1	0.023
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.023
SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	0.022
SPP2	secreted phosphoprotein 2, 24kDa	0.022
PROCR	protein C receptor, endothelial	0.021
RANBP9	RAN binding protein 9	0.021
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.021
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.021	Human Rat
IL1R1	interleukin 1 receptor, type I	0.021
RDH16	retinol dehydrogenase 16 (all-trans)	0.020
CRP	C-reactive protein, pentraxin-related	0.020
FTCD	formiminotransferase cyclodeaminase	0.020
TXN	thioredoxin	0.019
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.019	Human
ITIH2	inter-alpha (globulin) inhibitor H2	0.019
ASGR2	asialoglycoprotein receptor 2	0.018
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.017
ITIH1	inter-alpha (globulin) inhibitor H1	0.017
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.017	Human
APOA2	apolipoprotein A-II	0.017
SDPR	serum deprivation response	0.016
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.016
C8G	complement component 8, gamma polypeptide	0.016
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.016
ITIH3	inter-alpha (globulin) inhibitor H3	0.016
PDGFC	platelet derived growth factor C	0.016
F2	coagulation factor II (thrombin)	0.015
HABP2	hyaluronan binding protein 2	0.015	Human
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.014
IGFALS	insulin-like growth factor binding protein, acid labile subunit	0.014
APCS	amyloid P component, serum	0.014
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.014
OSMR	oncostatin M receptor	0.014
SPHK1	sphingosine kinase 1	0.014
INADL	InaD-like (Drosophila)	0.014
TFEC	transcription factor EC	0.014
CYR61	cysteine-rich, angiogenic inducer, 61	0.013
SAA4	serum amyloid A4, constitutive	0.013
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.013
APOA1	apolipoprotein A-I	0.013
SLC38A3	solute carrier family 38, member 3	0.013
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.013
CAV2	caveolin 2	0.012
LIPC	lipase, hepatic	0.012
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.012
TGFB1	transforming growth factor, beta 1	0.012
ECSIT	ECSIT homolog (Drosophila)	0.012
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.012
ALDOB	aldolase B, fructose-bisphosphate	0.012
CPB2	carboxypeptidase B2 (plasma)	0.012	Rat
APOB	apolipoprotein B (including Ag(x) antigen)	0.012
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.012
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.012
INHBA	inhibin, beta A	0.012
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.012
LRP1	low density lipoprotein receptor-related protein 1	0.012
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.011
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.011
PLCG1	phospholipase C, gamma 1	0.011
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.011
AMT	aminomethyltransferase	0.011
HPN	hepsin	0.011
EMP1	epithelial membrane protein 1	0.010
AGXT	alanine-glyoxylate aminotransferase	0.010
AFM	afamin	0.010
TNC	tenascin C	0.010
PXDN	peroxidasin homolog (Drosophila)	0.010
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.010