Homo sapiens

122 known processes

ACVR2B

activin A receptor, type IIB

(Aliases: MGC116908,ACTRIIB,ActR-IIB)

ACVR2B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 22 0.651
Human
positive regulation of cardioblast differentiation GO:0051891 2 0.243
catagen GO:0042637 3 0.224
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.220
Human
cellular amino acid metabolic process GO:0006520 116 0.142
regulation of cellular amine metabolic process GO:0033238 11 0.137
regulation of cellular amino acid metabolic process GO:0006521 6 0.135
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.127
regulation of cellular ketone metabolic process GO:0010565 50 0.125
amine metabolic process GO:0009308 44 0.125
cellular amine metabolic process GO:0044106 41 0.125
positive regulation of cellular amine metabolic process GO:0033240 7 0.111
post embryonic development GO:0009791 2 0.109
Mouse
cellular ketone metabolic process GO:0042180 80 0.105
regulation of cell differentiation GO:0045595 393 0.101
cytoplasmic transport GO:0016482 379 0.099
enzyme linked receptor protein signaling pathway GO:0007167 303 0.093
positive regulation of phosphorylation GO:0042327 394 0.093
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.090
epithelium development GO:0060429 227 0.089
Mouse
regulation of transferase activity GO:0051338 355 0.088
Mouse
glial cell migration GO:0008347 4 0.088
negative regulation of protein metabolic process GO:0051248 391 0.082
cell adhesion GO:0007155 325 0.081
cellular response to growth factor stimulus GO:0071363 197 0.081
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.081
negative regulation of multicellular organismal process GO:0051241 317 0.080
regulation of cell migration GO:0030334 289 0.079
positive regulation of protein phosphorylation GO:0001934 313 0.078
Human Mouse
regulation of protein localization GO:0032880 296 0.078
positive regulation of developmental process GO:0051094 314 0.078
system process GO:0003008 349 0.076
response to growth factor GO:0070848 205 0.074
Human
regulation of establishment of protein localization GO:0070201 242 0.073
regulation of ossification GO:0030278 58 0.072
cell development GO:0048468 328 0.072
Zebrafish
regulation of cell cycle GO:0051726 393 0.072
mitotic cell cycle GO:0000278 326 0.070
regulation of cell growth GO:0001558 135 0.070
endodermal cell fate commitment GO:0001711 4 0.070
mapk cascade GO:0000165 288 0.069
protein localization to organelle GO:0033365 280 0.069
positive regulation of cell proliferation GO:0008284 301 0.068
negative regulation of catalytic activity GO:0043086 335 0.068
nucleocytoplasmic transport GO:0006913 176 0.068
regulation of mapk cascade GO:0043408 262 0.068
biological adhesion GO:0022610 331 0.067
positive regulation of mapk cascade GO:0043410 190 0.067
regulation of intracellular transport GO:0032386 195 0.066
regulation of intracellular protein transport GO:0033157 123 0.065
cellular response to endogenous stimulus GO:0071495 336 0.065
Human
regulation of cell motility GO:2000145 299 0.064
regulation of cell cycle process GO:0010564 266 0.064
positive regulation of cell death GO:0010942 263 0.063
positive regulation of cell differentiation GO:0045597 211 0.063
segmentation GO:0035282 4 0.063
cell fate determination GO:0001709 3 0.063
signal transduction by phosphorylation GO:0023014 297 0.063
regulation of protein transport GO:0051223 213 0.062
negative regulation of cell proliferation GO:0008285 228 0.062
cellular component morphogenesis GO:0032989 314 0.062
digestive system development GO:0055123 75 0.062
Mouse
salivary gland morphogenesis GO:0007435 4 0.062
cellular response to oxygen containing compound GO:1901701 276 0.062
single organism cellular localization GO:1902580 332 0.061
response to oxygen containing compound GO:1901700 369 0.061
Mouse
positive regulation of protein kinase activity GO:0045860 190 0.060
Mouse
multicellular organismal aging GO:0010259 3 0.060
positive regulation of cellular component organization GO:0051130 376 0.060
positive regulation of transferase activity GO:0051347 227 0.060
Mouse
regulation of cellular component movement GO:0051270 334 0.060
growth GO:0040007 202 0.059
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.058
positive regulation of bone mineralization GO:0030501 19 0.058
protein targeting GO:0006605 187 0.058
response to abiotic stimulus GO:0009628 336 0.058
positive regulation of cytoplasmic transport GO:1903651 82 0.058
regulation of kinase activity GO:0043549 314 0.058
Mouse
positive regulation of programmed cell death GO:0043068 249 0.057
regulation of locomotion GO:0040012 329 0.057
mesenchymal cell development GO:0014031 50 0.057
Zebrafish
determination of adult lifespan GO:0008340 2 0.057
nervous system development GO:0007399 293 0.057
Zebrafish
regeneration GO:0031099 4 0.057
negative regulation of cell death GO:0060548 345 0.056
negative regulation of apoptotic process GO:0043066 316 0.056
positive regulation of transport GO:0051050 336 0.056
response to lipid GO:0033993 206 0.056
positive regulation of apoptotic process GO:0043065 246 0.056
negative regulation of cellular protein metabolic process GO:0032269 353 0.056
spinal cord development GO:0021510 4 0.055
mitotic cell cycle process GO:1903047 286 0.055
organ morphogenesis GO:0009887 147 0.055
Mouse
intracellular protein transport GO:0006886 270 0.055
immune system development GO:0002520 195 0.054
Human
positive regulation of cellular component movement GO:0051272 181 0.054
regulation of protein kinase activity GO:0045859 289 0.054
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.054
negative regulation of phosphate metabolic process GO:0045936 267 0.053
regulation of bone mineralization GO:0030500 29 0.053
regulation of epithelial cell migration GO:0010632 93 0.053
positive regulation of protein transport GO:0051222 135 0.052
negative regulation of developmental process GO:0051093 247 0.052
secretion by cell GO:0032940 226 0.052
Mouse
epithelial cell migration GO:0010631 119 0.051
positive regulation of immune system process GO:0002684 283 0.051
Human
cardiovascular system development GO:0072358 262 0.051
Mouse
peptidyl threonine phosphorylation GO:0018107 41 0.051
regulation of protein targeting GO:1903533 91 0.051
regulation of cytoplasmic transport GO:1903649 149 0.050
positive regulation of hydrolase activity GO:0051345 331 0.050
positive regulation of cell motility GO:2000147 177 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.050
regulation of dna metabolic process GO:0051052 153 0.050
mesenchyme development GO:0060485 59 0.050
Zebrafish
pathway restricted smad protein phosphorylation GO:0060389 38 0.050
Human
negative regulation of cell cycle GO:0045786 193 0.049
secretion GO:0046903 254 0.049
Mouse
negative regulation of cellular component movement GO:0051271 106 0.049
cell projection organization GO:0030030 252 0.049
nuclear transport GO:0051169 179 0.049
lipid metabolic process GO:0006629 381 0.049
immune response GO:0006955 307 0.048
apoptotic signaling pathway GO:0097190 268 0.048
cell morphogenesis GO:0000902 296 0.048
regulation of biomineral tissue development GO:0070167 31 0.048
regulation of protein serine threonine kinase activity GO:0071900 179 0.047
establishment of protein localization to organelle GO:0072594 172 0.047
regulation of epithelial cell proliferation GO:0050678 113 0.047
regulation of reactive oxygen species metabolic process GO:2000377 41 0.047
female gamete generation GO:0007292 2 0.045
defense response GO:0006952 315 0.045
regulation of cell adhesion GO:0030155 166 0.045
taxis GO:0042330 157 0.045
regulation of secretion GO:0051046 194 0.045
circulatory system development GO:0072359 262 0.045
Mouse
negative regulation of locomotion GO:0040013 118 0.044
negative regulation of programmed cell death GO:0043069 321 0.044
protein import GO:0017038 130 0.044
positive regulation of cell migration GO:0030335 172 0.044
regulation of endothelial cell migration GO:0010594 67 0.044
epithelium migration GO:0090132 119 0.044
mitotic cell cycle phase transition GO:0044772 162 0.044
protein localization to nucleus GO:0034504 136 0.043
carbohydrate metabolic process GO:0005975 207 0.043
reactive oxygen species metabolic process GO:0072593 75 0.043
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
neuron differentiation GO:0030182 138 0.043
regulation of catagen GO:0051794 3 0.043
regulation of growth GO:0040008 165 0.042
peptidyl threonine modification GO:0018210 45 0.042
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.042
negative regulation of epithelial cell migration GO:0010633 38 0.041
blood circulation GO:0008015 113 0.041
activation of protein kinase activity GO:0032147 90 0.041
Mouse
regulation of cell development GO:0060284 161 0.041
oogenesis GO:0048477 2 0.041
negative regulation of protein modification process GO:0031400 200 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
generation of neurons GO:0048699 152 0.040
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
chemotaxis GO:0006935 157 0.040
regulation of protein localization to nucleus GO:1900180 85 0.040
single organism membrane organization GO:0044802 268 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
epithelial cell proliferation GO:0050673 128 0.040
cell cycle phase transition GO:0044770 173 0.040
regulation of protein import into nucleus GO:0042306 78 0.040
negative regulation of cell growth GO:0030308 83 0.040
locomotory behavior GO:0007626 1 0.039
carbohydrate derivative biosynthetic process GO:1901137 207 0.039
connective tissue development GO:0061448 39 0.039
Zebrafish
purine ribonucleoside metabolic process GO:0046128 437 0.039
negative regulation of cell differentiation GO:0045596 171 0.039
hindbrain development GO:0030902 3 0.038
Zebrafish
protein catabolic process GO:0030163 325 0.038
endothelial cell migration GO:0043542 86 0.038
cytokine production GO:0001816 247 0.038
blastoderm segmentation GO:0007350 2 0.038
tissue migration GO:0090130 119 0.037
tube development GO:0035295 125 0.037
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.037
membrane organization GO:0061024 292 0.037
positive regulation of locomotion GO:0040017 186 0.037
response to organic cyclic compound GO:0014070 204 0.037
single organism carbohydrate metabolic process GO:0044723 193 0.036
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.036
digestive tract development GO:0048565 75 0.036
Mouse
regulation of cellular response to stress GO:0080135 244 0.036
response to transforming growth factor beta GO:0071559 94 0.036
regulation of smad protein import into nucleus GO:0060390 10 0.036
stem cell differentiation GO:0048863 93 0.036
Zebrafish
cation transport GO:0006812 331 0.036
positive regulation of catabolic process GO:0009896 310 0.035
cell morphogenesis involved in differentiation GO:0000904 144 0.035
anterior posterior axis specification GO:0009948 2 0.035
cellular lipid metabolic process GO:0044255 303 0.035
hemopoiesis GO:0030097 180 0.035
Human
neurogenesis GO:0022008 169 0.035
regulation of proteolysis GO:0030162 293 0.035
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.035
positive regulation of kinase activity GO:0033674 204 0.034
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.034
response to biotic stimulus GO:0009607 276 0.034
positive regulation of protein import into nucleus GO:0042307 46 0.034
protein import into nucleus GO:0006606 104 0.034
ameboidal type cell migration GO:0001667 135 0.034
Zebrafish
muscle cell fate commitment GO:0042693 4 0.034
negative regulation of trophoblast cell migration GO:1901164 3 0.034
purine ribonucleotide biosynthetic process GO:0009152 79 0.034
hematopoietic or lymphoid organ development GO:0048534 186 0.034
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.034
regulation of alkaline phosphatase activity GO:0010692 2 0.034
single organism cell adhesion GO:0098602 179 0.033
protein ubiquitination GO:0016567 314 0.033
regulation of secretion by cell GO:1903530 177 0.033
tissue regeneration GO:0042246 3 0.033
anatomical structure formation involved in morphogenesis GO:0048646 284 0.033
negative regulation of cell motility GO:2000146 104 0.033
extrinsic apoptotic signaling pathway GO:0097191 119 0.033
head development GO:0060322 108 0.033
Zebrafish
negative regulation of hydrolase activity GO:0051346 182 0.033
regulation of cytokine production GO:0001817 232 0.033
cell growth GO:0016049 160 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.032
organonitrogen compound biosynthetic process GO:1901566 200 0.032
regulation of cardioblast differentiation GO:0051890 4 0.032
negative regulation of cellular component organization GO:0051129 235 0.032
interspecies interaction between organisms GO:0044419 156 0.032
protein modification by small protein conjugation GO:0032446 342 0.032
regulation of activin receptor signaling pathway GO:0032925 14 0.032
dephosphorylation GO:0016311 209 0.031
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.031
negative regulation of dna metabolic process GO:0051053 57 0.031
actin filament based process GO:0030029 224 0.031
response to other organism GO:0051707 261 0.031
embryo development GO:0009790 123 0.031
Mouse
organophosphate biosynthetic process GO:0090407 163 0.030
regulation of response to external stimulus GO:0032101 222 0.030
chromatin modification GO:0016568 298 0.030
positive regulation of cytokine production GO:0001819 167 0.030
regulation of peptidase activity GO:0052547 180 0.030
regulation of stem cell differentiation GO:2000736 56 0.030
negative regulation of phosphorylation GO:0042326 174 0.030
hair cycle GO:0042633 28 0.030
negative regulation of protein phosphorylation GO:0001933 140 0.030
negative regulation of cell adhesion GO:0007162 64 0.030
negative regulation of alkaline phosphatase activity GO:0010693 2 0.030
cellular response to dna damage stimulus GO:0006974 379 0.030
response to external biotic stimulus GO:0043207 261 0.029
response to wounding GO:0009611 168 0.029
brain development GO:0007420 97 0.029
Zebrafish
regulation of cell morphogenesis GO:0022604 153 0.029
transmembrane transport GO:0055085 399 0.029
peptidyl serine phosphorylation GO:0018105 101 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
nuclear import GO:0051170 106 0.029
peptidyl serine modification GO:0018209 106 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
ossification GO:0001503 121 0.029
biomineral tissue development GO:0031214 39 0.029
urogenital system development GO:0001655 65 0.028
Mouse
response to hormone GO:0009725 175 0.028
single organismal cell cell adhesion GO:0016337 148 0.028
chemical homeostasis GO:0048878 306 0.028
nitrogen compound transport GO:0071705 191 0.028
Mouse
positive regulation of biomineral tissue development GO:0070169 20 0.028
defense response to fungus GO:0050832 4 0.028
ras protein signal transduction GO:0007265 73 0.028
negative regulation of growth GO:0045926 97 0.028
regulation of nucleocytoplasmic transport GO:0046822 98 0.028
protein targeting to nucleus GO:0044744 104 0.028
memory GO:0007613 3 0.027
wnt signaling pathway GO:0016055 156 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
motor neuron axon guidance GO:0008045 2 0.027
positive regulation of cell development GO:0010720 92 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
negative regulation of cell cycle process GO:0010948 121 0.027
cellular response to organic cyclic compound GO:0071407 127 0.027
purine containing compound catabolic process GO:0072523 411 0.027
positive regulation of fibroblast migration GO:0010763 3 0.026
central nervous system development GO:0007417 123 0.026
Zebrafish
cellular macromolecule catabolic process GO:0044265 380 0.026
positive regulation of protein localization to nucleus GO:1900182 48 0.026
blood vessel endothelial cell migration GO:0043534 42 0.026
positive regulation of intracellular transport GO:0032388 104 0.026
endomembrane system organization GO:0010256 196 0.026
nucleotide biosynthetic process GO:0009165 109 0.026
negative regulation of cell migration GO:0030336 102 0.026
neuroblast proliferation GO:0007405 4 0.026
pattern specification process GO:0007389 43 0.026
embryonic epithelial tube formation GO:0001838 4 0.026
purine nucleoside monophosphate metabolic process GO:0009126 186 0.026
dna replication GO:0006260 116 0.025
renal system development GO:0072001 63 0.025
Mouse
positive regulation of dna metabolic process GO:0051054 73 0.025
viral process GO:0016032 146 0.025
neuromuscular junction development GO:0007528 3 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
ribonucleoside monophosphate metabolic process GO:0009161 187 0.025
epithelial to mesenchymal transition GO:0001837 48 0.025
neuron projection development GO:0031175 106 0.025
regulation of dephosphorylation GO:0035303 96 0.025
regulation of map kinase activity GO:0043405 108 0.025
positive regulation of secretion by cell GO:1903532 108 0.024
cell cycle checkpoint GO:0000075 117 0.024
positive regulation of hair follicle maturation GO:0048818 2 0.024
cellular protein complex assembly GO:0043623 188 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
regulation of phosphatase activity GO:0010921 81 0.024
oocyte differentiation GO:0009994 2 0.024
organophosphate catabolic process GO:0046434 430 0.024
single organism nuclear import GO:1902593 104 0.024
metal ion transport GO:0030001 272 0.024
stem cell development GO:0048864 69 0.024
Zebrafish
ribonucleotide catabolic process GO:0009261 405 0.024
organ formation GO:0048645 3 0.024
mucopolysaccharide metabolic process GO:1903510 27 0.024
cellular response to lipid GO:0071396 127 0.024
tissue morphogenesis GO:0048729 96 0.024
regulation of protein secretion GO:0050708 86 0.024
response to fungus GO:0009620 4 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
positive regulation of secretion GO:0051047 116 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.023
cell projection morphogenesis GO:0048858 129 0.023
muscle structure development GO:0061061 98 0.023
circulatory system process GO:0003013 113 0.023
regulation of multi organism process GO:0043900 157 0.023
maintenance of location GO:0051235 112 0.023
negative regulation of endothelial cell migration GO:0010596 29 0.023
positive regulation of ossification GO:0045778 32 0.023
oocyte development GO:0048599 1 0.023
chromatin organization GO:0006325 351 0.023
regulation of system process GO:0044057 101 0.023
pituitary gland development GO:0021983 2 0.023
regulation of carbohydrate metabolic process GO:0006109 54 0.023
ion homeostasis GO:0050801 230 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.023
angiogenesis GO:0001525 147 0.023
cellular protein catabolic process GO:0044257 261 0.023
ion transmembrane transport GO:0034220 338 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.023
positive regulation of epithelial cell migration GO:0010634 55 0.023
positive regulation of intracellular protein transport GO:0090316 76 0.023
nucleoside catabolic process GO:0009164 408 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
cell part morphogenesis GO:0032990 137 0.022
cardiac epithelial to mesenchymal transition GO:0060317 3 0.022
skeletal system development GO:0001501 79 0.022
Zebrafish Mouse
regulation of cell cycle phase transition GO:1901987 126 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
cation homeostasis GO:0055080 189 0.022
cell cycle arrest GO:0007050 71 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.022
negative regulation of epithelial cell proliferation GO:0050680 48 0.022
positive regulation of map kinase activity GO:0043406 80 0.022
cell type specific apoptotic process GO:0097285 125 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
nucleoside phosphate biosynthetic process GO:1901293 109 0.022
positive regulation of organelle organization GO:0010638 195 0.022
embryonic morphogenesis GO:0048598 85 0.022
Mouse
somatic stem cell maintenance GO:0035019 4 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.022
nucleotide catabolic process GO:0009166 408 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
regulation of binding GO:0051098 111 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
atp metabolic process GO:0046034 176 0.021
tripartite regional subdivision GO:0007351 2 0.021
innate immune response GO:0045087 178 0.021
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.021
negative regulation of mitotic cell cycle GO:0045930 102 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
cell junction organization GO:0034330 79 0.021
positive regulation of immune response GO:0050778 159 0.021
heart morphogenesis GO:0003007 48 0.021
positive regulation of proteolysis GO:0045862 142 0.021
blood vessel development GO:0001568 172 0.021
Mouse
regulation of immune response GO:0050776 201 0.021
calcium ion transport GO:0006816 147 0.021
histone modification GO:0016570 251 0.021
regulation of heart contraction GO:0008016 50 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
response to drug GO:0042493 81 0.021
epithelial cell fate commitment GO:0072148 3 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
metal ion homeostasis GO:0055065 169 0.021
plasma membrane organization GO:0007009 115 0.020
metencephalon development GO:0022037 2 0.020
cartilage development GO:0051216 31 0.020
Zebrafish
positive regulation of cellular component biogenesis GO:0044089 158 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
nerve development GO:0021675 4 0.020
muscle system process GO:0003012 81 0.020
cellular homeostasis GO:0019725 196 0.020
activin receptor signaling pathway GO:0032924 24 0.020
neuron development GO:0048666 113 0.020
adult locomotory behavior GO:0008344 1 0.020
purine containing compound biosynthetic process GO:0072522 88 0.020
rho protein signal transduction GO:0007266 26 0.020
peripheral nervous system development GO:0007422 2 0.020
hair cycle process GO:0022405 12 0.020
osteoblast differentiation GO:0001649 92 0.020
modification of morphology or physiology of other organism GO:0035821 43 0.020
morphogenesis of an epithelium GO:0002009 60 0.020
regulation of protein catabolic process GO:0042176 155 0.020
protein maturation GO:0051604 233 0.020
positive regulation of hormone biosynthetic process GO:0046886 4 0.020
lipid biosynthetic process GO:0008610 177 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
blood vessel morphogenesis GO:0048514 162 0.019
cell matrix adhesion GO:0007160 85 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
negative regulation of transport GO:0051051 176 0.019
cardiac muscle cell fate commitment GO:0060923 4 0.019
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.019
positive regulation of cell cycle GO:0045787 140 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
covalent chromatin modification GO:0016569 254 0.019
atrioventricular valve development GO:0003171 3 0.019
protein dephosphorylation GO:0006470 81 0.019
morphogenesis of a polarized epithelium GO:0001738 3 0.019
cranial nerve development GO:0021545 4 0.019
divalent inorganic cation transport GO:0072511 158 0.019
specification of organ identity GO:0010092 3 0.019
regulation of hormone levels GO:0010817 125 0.019
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
cell division GO:0051301 168 0.019
regulation of cell cell adhesion GO:0022407 57 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
regulation of neuron differentiation GO:0045664 70 0.018
retinal ganglion cell axon guidance GO:0031290 2 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
purine nucleotide biosynthetic process GO:0006164 84 0.018
neural tube formation GO:0001841 3 0.018
heart development GO:0007507 95 0.018
Mouse
endoderm development GO:0007492 33 0.018
mesenchymal cell differentiation GO:0048762 52 0.018
Zebrafish
mitral valve development GO:0003174 3 0.018
vesicle mediated transport GO:0016192 371 0.018
kidney development GO:0001822 53 0.018
Mouse
receptor metabolic process GO:0043112 81 0.018
actin cytoskeleton organization GO:0030036 207 0.018
ncrna metabolic process GO:0034660 108 0.018
regionalization GO:0003002 29 0.018
stress activated protein kinase signaling cascade GO:0031098 94 0.018
response to radiation GO:0009314 151 0.018
bmp signaling pathway GO:0030509 49 0.018
cell substrate adhesion GO:0031589 132 0.018
negative regulation of blood pressure GO:0045776 3 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.018
establishment of planar polarity GO:0001736 3 0.018
regulation of homeostatic process GO:0032844 121 0.018
Human
compound eye development GO:0048749 1 0.017
circadian behavior GO:0048512 2 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
multi organism cellular process GO:0044764 156 0.017
protein processing GO:0016485 226 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
cardiac muscle tissue development GO:0048738 39 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.017
rhythmic behavior GO:0007622 2 0.017
regulation of protein complex assembly GO:0043254 147 0.017
cellular chemical homeostasis GO:0055082 180 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
negative regulation of immune system process GO:0002683 136 0.017
negative regulation of phosphatase activity GO:0010923 61 0.017

ACVR2B disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.031
nervous system disease DOID:863 431 0.031
musculoskeletal system disease DOID:17 223 0.029
disease of metabolism DOID:0014667 295 0.027
disease of cellular proliferation DOID:14566 174 0.023
cancer DOID:162 167 0.023
central nervous system disease DOID:331 186 0.022
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.021
organ system cancer DOID:0050686 164 0.021
inherited metabolic disorder DOID:655 242 0.019
retinal disease DOID:5679 118 0.018
connective tissue disease DOID:65 109 0.018