Homo sapiens

134 known processes

CDK6

cyclin-dependent kinase 6

(Aliases: MGC59692,PLSTIRE)

CDK6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
enteroendocrine cell differentiation GO:0035883 6 0.999
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.996
regulation of cell cycle arrest GO:0071156 36 0.993
Human
glandular epithelial cell development GO:0002068 5 0.993
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.989
autophagic cell death GO:0048102 3 0.949
regulation of cell cycle GO:0051726 393 0.942
negative regulation of cell proliferation GO:0008285 228 0.929
type b pancreatic cell development GO:0003323 4 0.928
regulation of cellular senescence GO:2000772 13 0.920
cell cycle arrest GO:0007050 71 0.908
Human
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.898
Human
cellular senescence GO:0090398 34 0.892
regulation of protein serine threonine kinase activity GO:0071900 179 0.890
organ morphogenesis GO:0009887 147 0.881
regulation of cell differentiation GO:0045595 393 0.875
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.873
Worm
g1 s transition of mitotic cell cycle GO:0000082 78 0.867
Human Worm
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.864
negative regulation of cell growth GO:0030308 83 0.858
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.845
cellular response to dna damage stimulus GO:0006974 379 0.835
positive regulation of cell development GO:0010720 92 0.828
cell cycle g2 m phase transition GO:0044839 43 0.815
Human
cell cycle checkpoint GO:0000075 117 0.809
regulation of protein kinase activity GO:0045859 289 0.804
regulation of cell growth GO:0001558 135 0.803
g2 m transition of mitotic cell cycle GO:0000086 41 0.792
Human
glandular epithelial cell differentiation GO:0002067 6 0.769
mitotic cell cycle process GO:1903047 286 0.766
Human Worm
positive regulation of cell cycle process GO:0090068 106 0.763
Human Worm
positive regulation of cell differentiation GO:0045597 211 0.752
mitotic g1 dna damage checkpoint GO:0031571 17 0.748
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 8 0.741
Human
canonical wnt signaling pathway GO:0060070 116 0.741
cell cycle g1 s phase transition GO:0044843 80 0.726
Human Worm
negative regulation of apoptotic process GO:0043066 316 0.710
cell development GO:0048468 328 0.709
regulation of growth GO:0040008 165 0.708
negative regulation of epithelial cell proliferation GO:0050680 48 0.702
neuron fate commitment GO:0048663 2 0.702
growth GO:0040007 202 0.684
Fly
type b pancreatic cell differentiation GO:0003309 5 0.677
cell activation GO:0001775 213 0.677
Mouse
regulation of kinase activity GO:0043549 314 0.667
positive regulation of fibroblast proliferation GO:0048146 21 0.665
epithelial cell differentiation GO:0030855 141 0.651
response to uv a GO:0070141 6 0.644
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.641
negative regulation of epithelial cell differentiation GO:0030857 6 0.638
hematopoietic or lymphoid organ development GO:0048534 186 0.628
regulation of cell cycle phase transition GO:1901987 126 0.621
Human Worm
cell growth GO:0016049 160 0.621
Fly
lymphocyte activation GO:0046649 133 0.619
Mouse
wnt signaling pathway GO:0016055 156 0.612
g1 dna damage checkpoint GO:0044783 18 0.606
positive regulation of cell cycle g2 m phase transition GO:1902751 8 0.596
Human
positive regulation of mitotic cell cycle GO:0045931 60 0.585
Human Worm
negative regulation of protein phosphorylation GO:0001933 140 0.584
positive regulation of apoptotic process involved in morphogenesis GO:1902339 1 0.579
regulation of wnt signaling pathway GO:0030111 123 0.575
response to vitamin GO:0033273 13 0.571
response to uv GO:0009411 73 0.570
myeloid cell differentiation GO:0030099 117 0.557
mitotic cell cycle GO:0000278 326 0.551
Human Worm Fly
cellular component morphogenesis GO:0032989 314 0.512
mitotic g1 s transition checkpoint GO:0044819 17 0.493
lymphocyte proliferation GO:0046651 70 0.488
regulation of endopeptidase activity GO:0052548 170 0.483
positive regulation of developmental process GO:0051094 314 0.482
negative regulation of cell differentiation GO:0045596 171 0.481
regulation of proteolysis GO:0030162 293 0.466
positive regulation of cell proliferation GO:0008284 301 0.447
negative regulation of phosphate metabolic process GO:0045936 267 0.441
epithelium development GO:0060429 227 0.439
regulation of cell development GO:0060284 161 0.439
negative regulation of leukocyte differentiation GO:1902106 24 0.435
regulation of cell cycle g2 m phase transition GO:1902749 22 0.433
Human
regulation of epithelial cell differentiation GO:0030856 24 0.426
mitotic dna damage checkpoint GO:0044773 28 0.426
cellular response to oxygen containing compound GO:1901701 276 0.423
regulation of response to dna damage stimulus GO:2001020 94 0.420
negative regulation of mitotic cell cycle GO:0045930 102 0.410
regulation of epithelial cell proliferation GO:0050678 113 0.406
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.406
regulation of neuron differentiation GO:0045664 70 0.404
negative regulation of cellular protein metabolic process GO:0032269 353 0.403
tissue morphogenesis GO:0048729 96 0.403
negative regulation of wnt signaling pathway GO:0030178 69 0.396
mitotic dna integrity checkpoint GO:0044774 30 0.390
response to nutrient GO:0007584 20 0.383
chromatin organization GO:0006325 351 0.382
positive regulation of cell cycle GO:0045787 140 0.382
Human Worm
negative regulation of myeloid cell differentiation GO:0045638 42 0.381
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.373
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.372
positive regulation of cell cycle arrest GO:0071158 23 0.371
regulation of canonical wnt signaling pathway GO:0060828 88 0.362
modification dependent macromolecule catabolic process GO:0043632 212 0.360
dna integrity checkpoint GO:0031570 71 0.357
cell cycle phase transition GO:0044770 173 0.350
Human Worm
negative regulation of axonogenesis GO:0050771 4 0.349
positive regulation of epithelial cell proliferation GO:0050679 65 0.349
negative regulation of growth GO:0045926 97 0.345
hemopoiesis GO:0030097 180 0.344
intrinsic apoptotic signaling pathway GO:0097193 127 0.338
regulation of nucleocytoplasmic transport GO:0046822 98 0.334
somatic stem cell maintenance GO:0035019 4 0.332
cell morphogenesis GO:0000902 296 0.331
regulation of transferase activity GO:0051338 355 0.329
regulation of mitotic cell cycle phase transition GO:1901990 118 0.329
Human Worm
segmentation GO:0035282 4 0.326
Fly
negative regulation of catalytic activity GO:0043086 335 0.319
response to abiotic stimulus GO:0009628 336 0.317
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.316
Human Worm
negative regulation of programmed cell death GO:0043069 321 0.313
somatic stem cell division GO:0048103 1 0.312
enzyme linked receptor protein signaling pathway GO:0007167 303 0.310
jak stat cascade GO:0007259 46 0.304
Fly
negative regulation of cell cycle process GO:0010948 121 0.291
Human
negative regulation of cell death GO:0060548 345 0.283
regulation of cell cycle g1 s phase transition GO:1902806 42 0.271
Worm
positive regulation of protein kinase activity GO:0045860 190 0.271
mitotic cell cycle checkpoint GO:0007093 68 0.270
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.268
post embryonic development GO:0009791 2 0.266
Worm
mitotic cell cycle phase transition GO:0044772 162 0.266
Human Worm
negative regulation of cell cycle GO:0045786 193 0.265
neuron differentiation GO:0030182 138 0.262
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.260
response to extracellular stimulus GO:0009991 85 0.257
regulation of peptidase activity GO:0052547 180 0.256
negative regulation of developmental process GO:0051093 247 0.254
t cell differentiation in thymus GO:0033077 4 0.252
Mouse
hair follicle morphogenesis GO:0031069 2 0.244
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.244
developmental programmed cell death GO:0010623 3 0.241
response to acid chemical GO:0001101 66 0.239
cellular response to lithium ion GO:0071285 2 0.238
neurogenesis GO:0022008 169 0.236
negative regulation of phosphorylation GO:0042326 174 0.233
negative regulation of kinase activity GO:0033673 106 0.230
negative regulation of proteolysis GO:0045861 132 0.227
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.226
negative regulation of multicellular organismal process GO:0051241 317 0.225
regulation of erythrocyte differentiation GO:0045646 17 0.224
protein modification by small protein conjugation GO:0032446 342 0.224
skeletal system development GO:0001501 79 0.223
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.223
positive regulation of phosphorylation GO:0042327 394 0.223
ras protein signal transduction GO:0007265 73 0.219
regulation of neurogenesis GO:0050767 82 0.214
regulation of reactive oxygen species metabolic process GO:2000377 41 0.211
lymphocyte differentiation GO:0030098 35 0.206
Mouse
regulation of cellular response to stress GO:0080135 244 0.206
mononuclear cell proliferation GO:0032943 71 0.205
response to lipid GO:0033993 206 0.203
protein ubiquitination GO:0016567 314 0.200
negative regulation of protein kinase activity GO:0006469 98 0.200
tube development GO:0035295 125 0.200
regulation of cell cycle process GO:0010564 266 0.196
Human Worm
sensory organ morphogenesis GO:0090596 21 0.194
osteoblast differentiation GO:0001649 92 0.193
positive regulation of wnt signaling pathway GO:0030177 54 0.190
positive regulation of transferase activity GO:0051347 227 0.190
notch signaling pathway GO:0007219 31 0.190
Mouse
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 1 0.189
positive regulation of protein phosphorylation GO:0001934 313 0.189
leukocyte differentiation GO:0002521 98 0.188
Mouse
regulation of mononuclear cell proliferation GO:0032944 65 0.187
negative regulation of protein modification process GO:0031400 200 0.187
negative regulation of cellular senescence GO:2000773 5 0.186
cell projection organization GO:0030030 252 0.184
response to radiation GO:0009314 151 0.182
regulation of leukocyte differentiation GO:1902105 61 0.177
dna damage checkpoint GO:0000077 68 0.177
cell type specific apoptotic process GO:0097285 125 0.177
regulation of leukocyte activation GO:0002694 115 0.174
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.173
leukocyte activation GO:0045321 164 0.172
Mouse
epithelial cell proliferation GO:0050673 128 0.171
regulation of mitotic cell cycle GO:0007346 189 0.170
Human Worm
response to nutrient levels GO:0031667 81 0.168
negative regulation of cell cycle arrest GO:0071157 12 0.167
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.166
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.163
response to light stimulus GO:0009416 87 0.163
immune system development GO:0002520 195 0.162
regeneration GO:0031099 4 0.160
response to calcium ion GO:0051592 46 0.160
regulation of myeloid cell differentiation GO:0045637 81 0.159
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.159
negative regulation of phosphorus metabolic process GO:0010563 267 0.159
positive regulation of cell death GO:0010942 263 0.158
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.157
regulation of fibroblast proliferation GO:0048145 32 0.155
leukocyte proliferation GO:0070661 74 0.154
branching morphogenesis of an epithelial tube GO:0048754 19 0.152
regulation of homeostatic process GO:0032844 121 0.150
apoptotic process involved in morphogenesis GO:0060561 3 0.148
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.148
negative regulation of peptidase activity GO:0010466 91 0.144
positive regulation of cell growth GO:0030307 48 0.143
tube morphogenesis GO:0035239 95 0.142
fibroblast proliferation GO:0048144 33 0.139
positive regulation of programmed cell death GO:0043068 249 0.138
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.134
generation of neurons GO:0048699 152 0.130
regulation of lymphocyte activation GO:0051249 103 0.130
columnar cuboidal epithelial cell development GO:0002066 5 0.130
hepaticobiliary system development GO:0061008 10 0.127
actin filament based process GO:0030029 224 0.127
response to magnesium ion GO:0032026 3 0.126
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.124
hematopoietic progenitor cell differentiation GO:0002244 38 0.123
Mouse
positive regulation of kinase activity GO:0033674 204 0.123
response to cytokine GO:0034097 232 0.121
regulation of ossification GO:0030278 58 0.119
protein processing GO:0016485 226 0.116
response to estradiol GO:0032355 23 0.115
regulation of cell adhesion GO:0030155 166 0.114
apoptotic signaling pathway GO:0097190 268 0.114
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.114
response to inorganic substance GO:0010035 127 0.112
response to organonitrogen compound GO:0010243 156 0.112
positive regulation of neurogenesis GO:0050769 49 0.112
regulation of apoptotic process involved in morphogenesis GO:1902337 1 0.111
negative regulation of intracellular signal transduction GO:1902532 183 0.109
negative regulation of apoptotic signaling pathway GO:2001234 97 0.107
positive regulation of proteolysis GO:0045862 142 0.106
response to alcohol GO:0097305 64 0.105
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.104
negative regulation of transferase activity GO:0051348 124 0.101
cell part morphogenesis GO:0032990 137 0.101
chromatin modification GO:0016568 298 0.101
response to retinoic acid GO:0032526 33 0.101
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.100
response to ionizing radiation GO:0010212 65 0.100
response to metal ion GO:0010038 84 0.099
cell aging GO:0007569 52 0.099
regulation of cell morphogenesis GO:0022604 153 0.098
regulation of cellular amine metabolic process GO:0033238 11 0.097
regulation of mammary gland epithelial cell proliferation GO:0033599 6 0.096
positive regulation of collateral sprouting GO:0048672 2 0.095
protein polyubiquitination GO:0000209 110 0.095
regulation of osteoblast differentiation GO:0045667 38 0.094
cartilage condensation GO:0001502 1 0.093
fat cell differentiation GO:0045444 32 0.093
peptidyl tyrosine phosphorylation GO:0018108 170 0.093
regulation of protein processing GO:0070613 150 0.093
response to oxygen containing compound GO:1901700 369 0.091
dna repair GO:0006281 198 0.090
cell dedifferentiation GO:0043697 1 0.090
response to ethanol GO:0045471 11 0.089
negative regulation of cell cycle phase transition GO:1901988 89 0.088
transmembrane transport GO:0055085 399 0.088
astrocyte differentiation GO:0048708 4 0.086
vesicle mediated transport GO:0016192 371 0.086
cellular response to growth factor stimulus GO:0071363 197 0.086
cell adhesion GO:0007155 325 0.085
nervous system development GO:0007399 293 0.085
cellular response to external stimulus GO:0071496 111 0.085
regulation of cellular component size GO:0032535 82 0.084
hematopoietic stem cell differentiation GO:0060218 4 0.083
Mouse
dna conformation change GO:0071103 113 0.083
small gtpase mediated signal transduction GO:0007264 78 0.082
cellular response to extracellular stimulus GO:0031668 72 0.080
multicellular organismal response to stress GO:0033555 1 0.079
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.076
glycerolipid catabolic process GO:0046503 18 0.075
mammary gland morphogenesis GO:0060443 2 0.075
er nucleus signaling pathway GO:0006984 23 0.075
regulation of lymphocyte proliferation GO:0050670 64 0.075
regulation of cell migration GO:0030334 289 0.075
mitochondrion organization GO:0007005 156 0.074
Fly
hindbrain development GO:0030902 3 0.073
cell fate determination GO:0001709 3 0.072
regulation of b cell activation GO:0050864 24 0.072
negative regulation of immune system process GO:0002683 136 0.071
positive regulation of cellular component organization GO:0051130 376 0.071
cellular amine metabolic process GO:0044106 41 0.071
cardiac ventricle formation GO:0003211 2 0.070
neuron projection development GO:0031175 106 0.069
regulation of dna replication GO:0006275 68 0.069
anatomical structure formation involved in morphogenesis GO:0048646 284 0.068
regulation of b cell proliferation GO:0030888 18 0.067
response to organic cyclic compound GO:0014070 204 0.067
positive regulation of response to dna damage stimulus GO:2001022 43 0.067
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 15 0.067
motor neuron axon guidance GO:0008045 2 0.067
regulation of protein ubiquitination GO:0031396 95 0.067
positive regulation of growth GO:0045927 58 0.066
ossification GO:0001503 121 0.066
response to transition metal nanoparticle GO:1990267 29 0.065
t cell proliferation GO:0042098 45 0.065
regulation of leukocyte proliferation GO:0070663 67 0.065
negative regulation of transport GO:0051051 176 0.064
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.064
establishment of planar polarity GO:0001736 3 0.063
cellular response to nitrogen compound GO:1901699 144 0.063
cell differentiation in spinal cord GO:0021515 1 0.062
positive regulation of endopeptidase activity GO:0010950 84 0.062
vasculature development GO:0001944 181 0.062
b cell activation GO:0042113 33 0.061
histone modification GO:0016570 251 0.061
regulation of anatomical structure morphogenesis GO:0022603 286 0.060
stem cell development GO:0048864 69 0.060
neuron development GO:0048666 113 0.059
dedifferentiation GO:0043696 1 0.059
cellular response to peptide GO:1901653 59 0.059
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.059
positive regulation of apoptotic process GO:0043065 246 0.059
regulation of protein catabolic process GO:0042176 155 0.059
pancreas development GO:0031016 19 0.058
cellular macromolecule catabolic process GO:0044265 380 0.058
cation homeostasis GO:0055080 189 0.058
lens development in camera type eye GO:0002088 2 0.058
positive regulation of leukocyte activation GO:0002696 80 0.058
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.058
blastoderm segmentation GO:0007350 2 0.057
Fly
endocrine pancreas development GO:0031018 11 0.057
response to other organism GO:0051707 261 0.057
reactive oxygen species metabolic process GO:0072593 75 0.057
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.057
positive regulation of cell cycle phase transition GO:1901989 22 0.057
Human Worm
cellular response to nutrient GO:0031670 12 0.056
internal peptidyl lysine acetylation GO:0018393 97 0.056
negative regulation of endopeptidase activity GO:0010951 84 0.056
negative regulation of phosphatase activity GO:0010923 61 0.055
endocrine system development GO:0035270 26 0.054
negative regulation of neurogenesis GO:0050768 26 0.054
epithelial cell development GO:0002064 34 0.054
dna biosynthetic process GO:0071897 40 0.054
cell projection morphogenesis GO:0048858 129 0.054
cellular response to endogenous stimulus GO:0071495 336 0.054
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.053
positive regulation of meiotic cell cycle GO:0051446 2 0.053
collateral sprouting GO:0048668 2 0.053
regulation of cytoplasmic transport GO:1903649 149 0.053
oogenesis GO:0048477 2 0.052
activation of cysteine type endopeptidase activity GO:0097202 57 0.051
chemotaxis GO:0006935 157 0.051
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.051
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.050
regulation of cell activation GO:0050865 125 0.050
embryonic skeletal system development GO:0048706 13 0.050
mammary gland epithelium development GO:0061180 10 0.050
tissue remodeling GO:0048771 16 0.050
rna processing GO:0006396 255 0.050
neutral lipid catabolic process GO:0046461 12 0.050
cellular response to unfolded protein GO:0034620 16 0.050
cellular response to organic cyclic compound GO:0071407 127 0.049
positive regulation of gliogenesis GO:0014015 4 0.049
cellular response to abiotic stimulus GO:0071214 117 0.049
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.049
regulation of cell aging GO:0090342 18 0.049
response to endoplasmic reticulum stress GO:0034976 49 0.049
compound eye development GO:0048749 1 0.049
positive regulation of muscle cell apoptotic process GO:0010661 4 0.049
positive regulation of neuron differentiation GO:0045666 40 0.049
posttranscriptional regulation of gene expression GO:0010608 213 0.049
myeloid leukocyte differentiation GO:0002573 60 0.049
positive regulation of peptidase activity GO:0010952 88 0.048
negative regulation of hydrolase activity GO:0051346 182 0.048
camera type eye development GO:0043010 25 0.048
sensory perception GO:0007600 103 0.048
stem cell division GO:0017145 2 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.048
response to vitamin d GO:0033280 10 0.047
endoplasmic reticulum unfolded protein response GO:0030968 16 0.046
dna packaging GO:0006323 77 0.046
negative regulation of dephosphorylation GO:0035305 63 0.046
amide transport GO:0042886 76 0.046
b cell proliferation GO:0042100 22 0.045
eye development GO:0001654 42 0.045
single organism reproductive process GO:0044702 98 0.044
Worm
morphogenesis of an epithelium GO:0002009 60 0.044
cellular response to lipid GO:0071396 127 0.044
regulation of cysteine type endopeptidase activity GO:2000116 127 0.043
mitotic cell cycle arrest GO:0071850 4 0.043
protein maturation GO:0051604 233 0.043
gland development GO:0048732 48 0.043
cellular component assembly involved in morphogenesis GO:0010927 73 0.043
regulation of hair follicle cell proliferation GO:0071336 1 0.043
morphogenesis of a polarized epithelium GO:0001738 3 0.043
cytoplasmic transport GO:0016482 379 0.043
dephosphorylation GO:0016311 209 0.042
cellular response to oxidative stress GO:0034599 85 0.042
organelle fission GO:0048285 149 0.042
Worm
neuroblast proliferation GO:0007405 4 0.042
lactation GO:0007595 3 0.041
cellular ketone metabolic process GO:0042180 80 0.041
regulation of t cell activation GO:0050863 77 0.041
regulation of ion transport GO:0043269 189 0.041
t cell activation GO:0042110 99 0.041
Mouse
monovalent inorganic cation transport GO:0015672 128 0.041
organelle assembly GO:0070925 176 0.040
developmental process involved in reproduction GO:0003006 66 0.040
Worm
regulation of locomotion GO:0040012 329 0.040
response to estrogen GO:0043627 47 0.040
response to camp GO:0051591 25 0.040
female gamete generation GO:0007292 2 0.040
regulation of cellular component movement GO:0051270 334 0.040
regulation of meiotic cell cycle GO:0051445 4 0.040
regulation of dendrite development GO:0050773 18 0.040
mammary gland development GO:0030879 17 0.040
spinal cord development GO:0021510 4 0.039
embryonic viscerocranium morphogenesis GO:0048703 1 0.039
cellular response to ionizing radiation GO:0071479 32 0.039
regulation of protein localization GO:0032880 296 0.039
organ formation GO:0048645 3 0.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.038
regulation of phosphatase activity GO:0010921 81 0.038
regulation of dephosphorylation GO:0035303 96 0.038
sex differentiation GO:0007548 45 0.038
Worm
sensory organ development GO:0007423 52 0.038
regulation of endothelial cell differentiation GO:0045601 4 0.037
regulation of organ morphogenesis GO:2000027 24 0.037
response to lithium ion GO:0010226 2 0.037
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.037
peptide hormone secretion GO:0030072 50 0.037
negative regulation of myeloid leukocyte differentiation GO:0002762 16 0.037
reproductive structure development GO:0048608 55 0.037
Worm
histone h3 acetylation GO:0043966 45 0.036
cell morphogenesis involved in differentiation GO:0000904 144 0.036
negative regulation of neuron differentiation GO:0045665 21 0.036
regulation of myeloid leukocyte differentiation GO:0002761 39 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.036
embryonic camera type eye development GO:0031076 2 0.035
regulation of cell motility GO:2000145 299 0.035
cellular macromolecular complex assembly GO:0034622 324 0.035
myosin filament assembly GO:0031034 2 0.035
regulation of granulocyte differentiation GO:0030852 11 0.035
skeletal system morphogenesis GO:0048705 24 0.035
intracellular bile acid receptor signaling pathway GO:0038185 1 0.035
system process GO:0003008 349 0.034
regulation of protein maturation GO:1903317 150 0.034
inner ear morphogenesis GO:0042472 4 0.034
carbohydrate metabolic process GO:0005975 207 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.034
regulation of astrocyte differentiation GO:0048710 3 0.034
establishment of tissue polarity GO:0007164 3 0.034
signal transduction by phosphorylation GO:0023014 297 0.034
taxis GO:0042330 157 0.034
hair cycle GO:0042633 28 0.034
cellular response to hydrogen peroxide GO:0070301 37 0.034
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.034
negative regulation of protein maturation GO:1903318 142 0.034
positive regulation of cell adhesion GO:0045785 84 0.033
regulation of neuron projection development GO:0010975 57 0.033
nucleocytoplasmic transport GO:0006913 176 0.033
cranial nerve development GO:0021545 4 0.033
positive regulation of chromosome organization GO:2001252 41 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9 0.033
embryonic epithelial tube formation GO:0001838 4 0.032
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.032
ion homeostasis GO:0050801 230 0.032
response to steroid hormone GO:0048545 80 0.032
pattern specification process GO:0007389 43 0.032
Fly
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 10 0.032
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.031
negative regulation of protein processing GO:0010955 142 0.031
cardiac right ventricle formation GO:0003219 1 0.031
striated muscle cell differentiation GO:0051146 43 0.031
nerve development GO:0021675 4 0.031
regulation of cell substrate adhesion GO:0010810 68 0.031
hair cell differentiation GO:0035315 2 0.030
embryonic organ development GO:0048568 36 0.030
reactive oxygen species biosynthetic process GO:1903409 4 0.030
cell substrate adhesion GO:0031589 132 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.030
regulation of ubiquitin protein transferase activity GO:0051438 28 0.030

CDK6 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.177
disease of cellular proliferation DOID:14566 174 0.177
immune system cancer DOID:0060083 36 0.177
organ system cancer DOID:0050686 164 0.177
bone marrow cancer DOID:4960 10 0.177
hematologic cancer DOID:2531 36 0.177
myeloma DOID:0070004 7 0.177
gastrointestinal system cancer DOID:3119 52 0.062
connective tissue disease DOID:65 109 0.061
bone disease DOID:0080001 88 0.061
musculoskeletal system disease DOID:17 223 0.061
colorectal cancer DOID:9256 29 0.045
large intestine cancer DOID:5672 29 0.045
intestinal cancer DOID:10155 29 0.045
colon cancer DOID:219 25 0.045
acute myeloid leukemia DOID:9119 17 0.037
myeloid leukemia DOID:8692 18 0.037
leukemia DOID:1240 21 0.037
nervous system disease DOID:863 431 0.030
sensory system disease DOID:0050155 203 0.030
eye and adnexa disease DOID:1492 150 0.030