Process View
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "g2 m transition of mitotic cell cycle"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
CDK2 | cyclin-dependent kinase 2 | 1.000 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 1.000 | ||
BRCA1 | breast cancer 1, early onset | 0.999 | ||
CCNE1 | cyclin E1 | 0.997 | ||
RB1 | retinoblastoma 1 | 0.991 | ||
SKP1 | S-phase kinase-associated protein 1 | 0.985 | Yeast | |
CCND3 | cyclin D3 | 0.983 | Human | |
JUN | jun proto-oncogene | 0.966 | ||
CCND1 | cyclin D1 | 0.917 | ||
FOXM1 | forkhead box M1 | 0.913 | ||
PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.899 | ||
RAD51L3 | RAD51-like 3 (S. cerevisiae) | 0.889 | ||
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.884 | ||
RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.851 | ||
NBN | nibrin | 0.848 | ||
MDC1 | mediator of DNA-damage checkpoint 1 | 0.825 | ||
CDK6 | cyclin-dependent kinase 6 | 0.792 | Human | |
BRCA2 | breast cancer 2, early onset | 0.756 | ||
C19orf39 | chromosome 19 open reading frame 39 | 0.700 | ||
CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.666 | ||
FANCD2 | Fanconi anemia, complementation group D2 | 0.657 | ||
PLK1 | polo-like kinase 1 | 0.623 | ||
CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.619 | ||
CCNA2 | cyclin A2 | 0.587 | ||
H2AFX | H2A histone family, member X | 0.577 | ||
E2F1 | E2F transcription factor 1 | 0.559 | ||
MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.537 | ||
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.534 | Fly | |
SKP2 | S-phase kinase-associated protein 2 (p45) | 0.532 | Mouse | |
CDK9 | cyclin-dependent kinase 9 | 0.525 | ||
CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.507 | Mouse Rat | |
BTRC | beta-transducin repeat containing | 0.480 | ||
CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.471 | Human Zebrafish Fly | |
BLM | Bloom syndrome, RecQ helicase-like | 0.468 | ||
CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.458 | ||
MEIS1 | Meis homeobox 1 | 0.456 | ||
ATR | ataxia telangiectasia and Rad3 related | 0.440 | Fly | |
CDHR2 | cadherin-related family member 2 | 0.438 | ||
FBXW11 | F-box and WD repeat domain containing 11 | 0.361 | ||
PRNP | prion protein | 0.340 | ||
MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.335 | ||
RAD50 | RAD50 homolog (S. cerevisiae) | 0.333 | ||
RBL1 | retinoblastoma-like 1 (p107) | 0.309 | ||
MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.290 | ||
JUNB | jun B proto-oncogene | 0.284 | ||
CDC45 | cell division cycle 45 homolog (S. cerevisiae) | 0.274 | ||
RAD51L1 | RAD51-like 1 (S. cerevisiae) | 0.266 | ||
PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.266 | ||
RBBP7 | retinoblastoma binding protein 7 | 0.264 | ||
CDK1 | cyclin-dependent kinase 1 | 0.260 | Fly | |
CUL1 | cullin 1 | 0.258 | Yeast | |
KEAP1 | kelch-like ECH-associated protein 1 | 0.251 | ||
LIN9 | lin-9 homolog (C. elegans) | 0.251 | ||
SKA1 | spindle and kinetochore associated complex subunit 1 | 0.243 | ||
TCP1 | t-complex 1 | 0.241 | ||
SNAI1 | snail homolog 1 (Drosophila) | 0.236 | ||
MSH6 | mutS homolog 6 (E. coli) | 0.232 | ||
CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.212 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.210 | ||
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.203 | ||
XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 0.197 | ||
NUP133 | nucleoporin 133kDa | 0.191 | ||
CDT1 | chromatin licensing and DNA replication factor 1 | 0.189 | ||
XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | 0.171 | ||
CCNB2 | cyclin B2 | 0.162 | Yeast | |
MCM2 | minichromosome maintenance complex component 2 | 0.159 | ||
IER2 | immediate early response 2 | 0.157 | ||
PDE4DIP | phosphodiesterase 4D interacting protein | 0.151 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.150 | ||
SMAD1 | SMAD family member 1 | 0.150 | ||
PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.148 | ||
TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.148 | ||
JUND | jun D proto-oncogene | 0.144 | ||
DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.144 | ||
ARID1A | AT rich interactive domain 1A (SWI-like) | 0.139 | ||
DDIT3 | DNA-damage-inducible transcript 3 | 0.138 | ||
TIMELESS | timeless homolog (Drosophila) | 0.138 | ||
CHMP1A | chromatin modifying protein 1A | 0.136 | ||
NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.136 | Human | |
ATF3 | activating transcription factor 3 | 0.133 | Fly | |
PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.132 | Fly | |
PGR | progesterone receptor | 0.132 | ||
ATM | ataxia telangiectasia mutated | 0.126 | ||
ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.125 | ||
NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.123 | ||
CLSPN | claspin | 0.120 | ||
ELAVL3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.117 | ||
PBK | PDZ binding kinase | 0.116 | ||
IRF2BP1 | interferon regulatory factor 2 binding protein 1 | 0.115 | ||
CCNT1 | cyclin T1 | 0.112 | ||
CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.108 | ||
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.101 | ||
CCNB1 | cyclin B1 | 0.101 | Yeast | |
MEIS2 | Meis homeobox 2 | 0.100 | ||
TP53BP1 | tumor protein p53 binding protein 1 | 0.098 | ||
HIPK2 | homeodomain interacting protein kinase 2 | 0.097 | ||
TERF2 | telomeric repeat binding factor 2 | 0.091 | Human | |
YAP1 | Yes-associated protein 1 | 0.091 | ||
RUNX1 | runt-related transcription factor 1 | 0.091 | ||
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.083 | ||
PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.082 | ||
USHBP1 | Usher syndrome 1C binding protein 1 | 0.082 | ||
MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | 0.081 | Fly | |
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.080 | ||
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.080 | ||
ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.078 | ||
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.075 | ||
MCM10 | minichromosome maintenance complex component 10 | 0.074 | ||
NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | 0.073 | ||
BCL6 | B-cell CLL/lymphoma 6 | 0.069 | ||
AKAP12 | A kinase (PRKA) anchor protein 12 | 0.068 | ||
NUP107 | nucleoporin 107kDa | 0.067 | ||
WEE1 | WEE1 homolog (S. pombe) | 0.063 | ||
BAG6 | BCL2-associated athanogene 6 | 0.062 | ||
WRN | Werner syndrome, RecQ helicase-like | 0.062 | ||
LIN54 | lin-54 homolog (C. elegans) | 0.061 | ||
FOSL1 | FOS-like antigen 1 | 0.061 | Fly | |
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.060 | Yeast | |
CCNF | cyclin F | 0.060 | ||
DOCK7 | dedicator of cytokinesis 7 | 0.060 | ||
RAD52 | RAD52 homolog (S. cerevisiae) | 0.059 | ||
SLX4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | 0.058 | ||
FBXW7 | F-box and WD repeat domain containing 7 | 0.057 | Yeast | |
GATAD2B | GATA zinc finger domain containing 2B | 0.057 | ||
ASF1B | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.056 | ||
MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.056 | ||
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 0.053 | ||
MEOX2 | mesenchyme homeobox 2 | 0.053 | ||
ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.052 | ||
CCND2 | cyclin D2 | 0.052 | Human | |
TBP | TATA box binding protein | 0.049 | ||
POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.049 | ||
MECP2 | methyl CpG binding protein 2 (Rett syndrome) | 0.048 | ||
CDC7 | cell division cycle 7 homolog (S. cerevisiae) | 0.048 | ||
BCL3 | B-cell CLL/lymphoma 3 | 0.048 | ||
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.047 | ||
CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.047 | ||
PSEN1 | presenilin 1 | 0.046 | ||
ORC2 | origin recognition complex, subunit 2 | 0.045 | ||
E2F4 | E2F transcription factor 4, p107/p130-binding | 0.045 | ||
HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | 0.044 | ||
ORC1 | origin recognition complex, subunit 1 | 0.044 | ||
SKA3 | spindle and kinetochore associated complex subunit 3 | 0.044 | ||
CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.043 | ||
SFN | stratifin | 0.042 | ||
MBD2 | methyl-CpG binding domain protein 2 | 0.042 | ||
CCNE2 | cyclin E2 | 0.041 | ||
CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.041 | ||
CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.041 | ||
POLE2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.041 | ||
JMJD6 | jumonji domain containing 6 | 0.040 | ||
CDHR5 | cadherin-related family member 5 | 0.040 | ||
RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.039 | ||
SERTAD4 | SERTA domain containing 4 | 0.039 | ||
RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.038 | ||
RBBP4 | retinoblastoma binding protein 4 | 0.038 | ||
RNF8 | ring finger protein 8 | 0.038 | ||
H1F0 | H1 histone family, member 0 | 0.038 | ||
RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.037 | ||
CUL2 | cullin 2 | 0.036 | ||
TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.036 | ||
EEF2K | eukaryotic elongation factor-2 kinase | 0.036 | ||
STK38L | serine/threonine kinase 38 like | 0.035 | ||
NCOR2 | nuclear receptor corepressor 2 | 0.035 | ||
MAPK10 | mitogen-activated protein kinase 10 | 0.034 | ||
ZSWIM7 | zinc finger, SWIM-type containing 7 | 0.034 | ||
SETDB1 | SET domain, bifurcated 1 | 0.034 | ||
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.034 | Human | |
MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 0.034 | ||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.033 | ||
DUSP1 | dual specificity phosphatase 1 | 0.032 | ||
EGR1 | early growth response 1 | 0.032 | ||
LMNA | lamin A/C | 0.031 | ||
SLC9A3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.031 | ||
APP | amyloid beta (A4) precursor protein | 0.031 | Mouse | |
TXNIP | thioredoxin interacting protein | 0.031 | ||
RIF1 | RAP1 interacting factor homolog (yeast) | 0.030 | ||
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.030 | ||
HBEGF | heparin-binding EGF-like growth factor | 0.030 | ||
ENO2 | enolase 2 (gamma, neuronal) | 0.030 | ||
PRC1 | protein regulator of cytokinesis 1 | 0.030 | ||
HDAC4 | histone deacetylase 4 | 0.030 | ||
VEZF1 | vascular endothelial zinc finger 1 | 0.029 | ||
ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.029 | ||
UBA5 | ubiquitin-like modifier activating enzyme 5 | 0.029 | ||
MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.029 | ||
ADAMTS10 | ADAM metallopeptidase with thrombospondin type 1 motif, 10 | 0.029 | ||
C6orf136 | chromosome 6 open reading frame 136 | 0.028 | ||
RECQL4 | RecQ protein-like 4 | 0.028 | ||
PCGF2 | polycomb group ring finger 2 | 0.027 | ||
ATRIP | ATR interacting protein | 0.027 | ||
PPME1 | protein phosphatase methylesterase 1 | 0.027 | ||
CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.026 | ||
XPO1 | exportin 1 (CRM1 homolog, yeast) | 0.026 | ||
FHL1 | four and a half LIM domains 1 | 0.026 | ||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.025 | ||
JUB | jub, ajuba homolog (Xenopus laevis) | 0.025 | ||
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.025 | ||
USP16 | ubiquitin specific peptidase 16 | 0.025 | ||
HDGF | hepatoma-derived growth factor | 0.024 | ||
ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.024 | ||
RFWD2 | ring finger and WD repeat domain 2 | 0.024 | ||
CDK4 | cyclin-dependent kinase 4 | 0.024 | ||
ARIH2 | ariadne homolog 2 (Drosophila) | 0.024 | ||
TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.024 | ||
RABGAP1 | RAB GTPase activating protein 1 | 0.024 | ||
FBXO5 | F-box protein 5 | 0.024 | ||
DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 | 0.023 | ||
FBXO4 | F-box protein 4 | 0.023 | ||
IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 0.023 | ||
RBBP8 | retinoblastoma binding protein 8 | 0.023 | ||
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.023 | ||
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.023 | ||
FBXW2 | F-box and WD repeat domain containing 2 | 0.023 | ||
RAD9A | RAD9 homolog A (S. pombe) | 0.023 | ||
TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.023 | Fly | |
ATMIN | ATM interactor | 0.023 | ||
PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.023 | Yeast | |
MBD3 | methyl-CpG binding domain protein 3 | 0.022 | ||
MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.022 | ||
PDCD6 | programmed cell death 6 | 0.022 | ||
GTSE1 | G-2 and S-phase expressed 1 | 0.022 | ||
TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.022 | ||
TPD52L1 | tumor protein D52-like 1 | 0.022 | ||
PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 0.021 | ||
DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.021 | ||
CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.021 | ||
TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa | 0.021 | ||
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.021 | ||
HIST1H4F | histone cluster 1, H4f | 0.021 | ||
CDK12 | cyclin-dependent kinase 12 | 0.021 | ||
MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.021 | ||
GLRX3 | glutaredoxin 3 | 0.020 | ||
BIRC5 | baculoviral IAP repeat containing 5 | 0.020 | ||
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.020 | ||
MESDC2 | mesoderm development candidate 2 | 0.020 | ||
PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.020 | Mouse | |
KRTAP4-12 | keratin associated protein 4-12 | 0.020 | ||
AZIN1 | antizyme inhibitor 1 | 0.020 | ||
TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.020 | ||
LARP7 | La ribonucleoprotein domain family, member 7 | 0.020 | ||
CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.019 | ||
MTA1 | metastasis associated 1 | 0.019 | ||
PPP4C | protein phosphatase 4, catalytic subunit | 0.019 | ||
AMOT | angiomotin | 0.019 | ||
SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.019 | ||
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.019 | ||
CSRNP1 | cysteine-serine-rich nuclear protein 1 | 0.019 | ||
CDC25B | cell division cycle 25 homolog B (S. pombe) | 0.019 | Human Zebrafish Fly | |
MAFK | v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) | 0.019 | ||
BACE1 | beta-site APP-cleaving enzyme 1 | 0.018 | ||
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.018 | ||
LMTK2 | lemur tyrosine kinase 2 | 0.018 | ||
DBN1 | drebrin 1 | 0.018 | ||
DCLRE1B | DNA cross-link repair 1B | 0.018 | ||
AMOTL2 | angiomotin like 2 | 0.018 | ||
MUS81 | MUS81 endonuclease homolog (S. cerevisiae) | 0.018 | ||
AMOTL1 | angiomotin like 1 | 0.018 | ||
SPAG5 | sperm associated antigen 5 | 0.018 | ||
APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.018 | ||
KLF4 | Kruppel-like factor 4 (gut) | 0.017 | ||
SMC1A | structural maintenance of chromosomes 1A | 0.017 | ||
ERCC4 | excision repair cross-complementing rodent repair deficiency, complementation group 4 | 0.017 | ||
POLQ | polymerase (DNA directed), theta | 0.017 | ||
ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.017 | ||
HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.017 | ||
FANCC | Fanconi anemia, complementation group C | 0.017 | ||
NRIP1 | nuclear receptor interacting protein 1 | 0.017 | ||
ACTL6B | actin-like 6B | 0.017 | ||
CIZ1 | CDKN1A interacting zinc finger protein 1 | 0.017 | ||
ATF2 | activating transcription factor 2 | 0.017 | ||
TCTEX1D2 | Tctex1 domain containing 2 | 0.017 | ||
SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.017 | ||
ZCCHC8 | zinc finger, CCHC domain containing 8 | 0.017 | ||
CUL5 | cullin 5 | 0.017 | ||
PARP1 | poly (ADP-ribose) polymerase 1 | 0.017 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.017 | ||
TMEM194A | transmembrane protein 194A | 0.017 | ||
SKA2 | spindle and kinetochore associated complex subunit 2 | 0.017 | ||
TRAP1 | TNF receptor-associated protein 1 | 0.017 | ||
AHCTF1 | AT hook containing transcription factor 1 | 0.017 | ||
RAD54L | RAD54-like (S. cerevisiae) | 0.017 | ||
NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.016 | ||
CHD8 | chromodomain helicase DNA binding protein 8 | 0.016 | ||
CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.016 | ||
CALR | calreticulin | 0.016 | ||
CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 0.016 | ||
ZFP28 | zinc finger protein 28 homolog (mouse) | 0.016 | ||
ZBTB17 | zinc finger and BTB domain containing 17 | 0.016 | ||
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.016 | ||
BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 0.016 | ||
LDHB | lactate dehydrogenase B | 0.016 | ||
TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.016 | ||
COBRA1 | cofactor of BRCA1 | 0.016 | ||
SMAD3 | SMAD family member 3 | 0.016 | ||
CDCA4 | cell division cycle associated 4 | 0.016 | ||
BTBD1 | BTB (POZ) domain containing 1 | 0.016 | ||
NLK | nemo-like kinase | 0.016 | ||
ZNF655 | zinc finger protein 655 | 0.016 | ||
TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 0.016 | ||
GATAD2A | GATA zinc finger domain containing 2A | 0.016 | ||
HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.016 | ||
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.016 | ||
TFDP1 | transcription factor Dp-1 | 0.016 | ||
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 0.016 | ||
SH2D1A | SH2 domain containing 1A | 0.016 | ||
TPD52 | tumor protein D52 | 0.016 | Human | |
ERCC6L | excision repair cross-complementing rodent repair deficiency, complementation group 6-like | 0.015 | ||
DCLRE1C | DNA cross-link repair 1C | 0.015 | ||
GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.015 | ||
SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.015 | ||
ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 0.015 | Human | |
DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.015 | ||
NOL8 | nucleolar protein 8 | 0.015 | ||
PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.015 | ||
NEMF | nuclear export mediator factor | 0.015 | ||
RAB3A | RAB3A, member RAS oncogene family | 0.015 | ||
A2M | alpha-2-macroglobulin | 0.015 | ||
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.015 | ||
CCDC6 | coiled-coil domain containing 6 | 0.015 | ||
CHAF1B | chromatin assembly factor 1, subunit B (p60) | 0.015 | ||
FBXO33 | F-box protein 33 | 0.015 | ||
RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.015 | ||
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.015 | ||
CD2 | CD2 molecule | 0.015 | ||
NFIB | nuclear factor I/B | 0.015 | ||
HMGXB3 | HMG box domain containing 3 | 0.014 | ||
RAD18 | RAD18 homolog (S. cerevisiae) | 0.014 | ||
PKM2 | pyruvate kinase, muscle | 0.014 | ||
MAF1 | MAF1 homolog (S. cerevisiae) | 0.014 | ||
GOLT1B | golgi transport 1B | 0.014 | ||
MOBKL1A | MOB1, Mps One Binder kinase activator-like 1A (yeast) | 0.014 | ||
LRCH2 | leucine-rich repeats and calponin homology (CH) domain containing 2 | 0.014 | ||
LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.014 | ||
SOX4 | SRY (sex determining region Y)-box 4 | 0.014 | ||
GPR135 | G protein-coupled receptor 135 | 0.014 | ||
FAM50A | family with sequence similarity 50, member A | 0.014 | ||
APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.014 | ||
JDP2 | Jun dimerization protein 2 | 0.014 | Fly | |
USH1G | Usher syndrome 1G (autosomal recessive) | 0.014 | ||
C22orf39 | chromosome 22 open reading frame 39 | 0.014 | ||
CNTROB | centrobin, centrosomal BRCA2 interacting protein | 0.014 | ||
TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa | 0.014 | ||
PPARA | peroxisome proliferator-activated receptor alpha | 0.014 | ||
TCF19 | transcription factor 19 | 0.014 | ||
PPP1R14A | protein phosphatase 1, regulatory (inhibitor) subunit 14A | 0.013 | ||
SFSWAP | splicing factor, suppressor of white-apricot homolog (Drosophila) | 0.013 | ||
TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | 0.013 | ||
MYO7B | myosin VIIB | 0.013 | ||
EXO1 | exonuclease 1 | 0.013 | ||
FOXP1 | forkhead box P1 | 0.013 | ||
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.013 | ||
BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) | 0.013 | ||
GORAB | golgin, RAB6-interacting | 0.013 | ||
MED12 | mediator complex subunit 12 | 0.013 | ||
SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.013 | ||
LOXL4 | lysyl oxidase-like 4 | 0.013 | ||
EP300 | E1A binding protein p300 | 0.013 | ||
UIMC1 | ubiquitin interaction motif containing 1 | 0.013 | ||
NLRP2 | NLR family, pyrin domain containing 2 | 0.013 | ||
ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.013 | ||
TROAP | trophinin associated protein (tastin) | 0.013 | ||
PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.013 | ||
STK39 | serine threonine kinase 39 | 0.013 | ||
KDM6B | lysine (K)-specific demethylase 6B | 0.013 | ||
GSG2 | germ cell associated 2 (haspin) | 0.013 | ||
CDK14 | cyclin-dependent kinase 14 | 0.013 | ||
AXIN2 | axin 2 | 0.013 | ||
MYH10 | myosin, heavy chain 10, non-muscle | 0.013 | ||
TRAF4 | TNF receptor-associated factor 4 | 0.013 | ||
BCL10 | B-cell CLL/lymphoma 10 | 0.013 | ||
GAS2L3 | growth arrest-specific 2 like 3 | 0.013 | ||
ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.013 | ||
RHOB | ras homolog gene family, member B | 0.013 | ||
LIMK1 | LIM domain kinase 1 | 0.013 | ||
EME1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.012 | ||
DCAF7 | DDB1 and CUL4 associated factor 7 | 0.012 | ||
ZW10 | ZW10, kinetochore associated, homolog (Drosophila) | 0.012 | ||
PER1 | period homolog 1 (Drosophila) | 0.012 | ||
CCNA1 | cyclin A1 | 0.012 | ||
LIMD1 | LIM domains containing 1 | 0.012 | ||
MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 0.012 | ||
FOXO1 | forkhead box O1 | 0.012 | ||
C20orf94 | chromosome 20 open reading frame 94 | 0.012 | ||
PFN2 | profilin 2 | 0.012 | ||
ING1 | inhibitor of growth family, member 1 | 0.012 | ||
ING2 | inhibitor of growth family, member 2 | 0.012 | ||
RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.012 | ||
UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.012 | ||
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.012 | ||
PIM1 | pim-1 oncogene | 0.012 | ||
STK36 | serine/threonine kinase 36 | 0.012 | ||
BTG3 | BTG family, member 3 | 0.012 | ||
PTMA | prothymosin, alpha | 0.012 | ||
PCM1 | pericentriolar material 1 | 0.012 | ||
BTG2 | BTG family, member 2 | 0.012 | ||
RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) | 0.012 | ||
MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.012 | ||
ZNF420 | zinc finger protein 420 | 0.012 | ||
SRRM2 | serine/arginine repetitive matrix 2 | 0.012 | ||
NDE1 | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 0.012 | ||
HIST1H3B | histone cluster 1, H3b | 0.012 | ||
ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.012 | ||
DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.012 | ||
RNF32 | ring finger protein 32 | 0.012 | ||
PALB2 | partner and localizer of BRCA2 | 0.012 | ||
NGFR | nerve growth factor receptor | 0.012 | ||
SEPT7 | septin 7 | 0.012 | ||
ELL | elongation factor RNA polymerase II | 0.012 | ||
GEN1 | Gen homolog 1, endonuclease (Drosophila) | 0.012 | ||
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.012 | ||
TAF4 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | 0.011 | ||
SMG5 | Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) | 0.011 | ||
ANKRD32 | ankyrin repeat domain 32 | 0.011 | ||
E2F2 | E2F transcription factor 2 | 0.011 | ||
WDR62 | WD repeat domain 62 | 0.011 | ||
C10orf18 | chromosome 10 open reading frame 18 | 0.011 | ||
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.011 | ||
ATXN2L | ataxin 2-like | 0.011 | ||
TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.011 | ||
ANKRD28 | ankyrin repeat domain 28 | 0.011 | ||
ZNF267 | zinc finger protein 267 | 0.011 | ||
SLC6A8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 0.011 | ||
PIAS4 | protein inhibitor of activated STAT, 4 | 0.011 | ||
SMC4 | structural maintenance of chromosomes 4 | 0.011 | ||
PRRC2A | proline-rich coiled-coil 2A | 0.011 | ||
CDH23 | cadherin-related 23 | 0.011 | ||
EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.011 | Fly | |
PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.011 | ||
HDAC1 | histone deacetylase 1 | 0.011 | ||
CARM1 | coactivator-associated arginine methyltransferase 1 | 0.011 | ||
FBRS | fibrosin | 0.011 | ||
PLK3 | polo-like kinase 3 | 0.011 | Human | |
FEM1B | fem-1 homolog b (C. elegans) | 0.011 | ||
TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 0.011 | ||
FAM57B | family with sequence similarity 57, member B | 0.011 | ||
ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.011 | ||
ARNT | aryl hydrocarbon receptor nuclear translocator | 0.011 | ||
TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.011 | ||
AFF4 | AF4/FMR2 family, member 4 | 0.011 | ||
TRMT61B | tRNA methyltransferase 61 homolog B (S. cerevisiae) | 0.011 | ||
TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 0.011 | ||
HOXA1 | homeobox A1 | 0.011 | ||
PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.011 | ||
FBXW5 | F-box and WD repeat domain containing 5 | 0.011 | ||
ALAS1 | aminolevulinate, delta-, synthase 1 | 0.011 | ||
ZNF367 | zinc finger protein 367 | 0.011 | ||
CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.010 | ||
KIF2A | kinesin heavy chain member 2A | 0.010 | ||
GFI1B | growth factor independent 1B transcription repressor | 0.010 | ||
KCTD9 | potassium channel tetramerisation domain containing 9 | 0.010 | ||
ZNF71 | zinc finger protein 71 | 0.010 | ||
PAPD7 | PAP associated domain containing 7 | 0.010 | ||
CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | 0.010 | ||
DNM1L | dynamin 1-like | 0.010 | ||
FAM64A | family with sequence similarity 64, member A | 0.010 | ||
RAD51C | RAD51 homolog C (S. cerevisiae) | 0.010 | ||
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.010 | ||
TSC22D4 | TSC22 domain family, member 4 | 0.010 | ||
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.010 | ||
TESK1 | testis-specific kinase 1 | 0.010 | ||
BCAS2 | breast carcinoma amplified sequence 2 | 0.010 | ||
BATF2 | basic leucine zipper transcription factor, ATF-like 2 | 0.010 | ||
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.010 | ||
INADL | InaD-like (Drosophila) | 0.010 | ||
SMC6 | structural maintenance of chromosomes 6 | 0.010 | ||
PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.010 | ||
SNRK | SNF related kinase | 0.010 | ||
KIF2C | kinesin family member 2C | 0.010 | ||
TRIM37 | tripartite motif containing 37 | 0.010 |