IMP
Process View
cell dedifferentiation
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cell dedifferentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.647 | ||
| IL4R | interleukin 4 receptor | 0.588 | ||
| CCND1 | cyclin D1 | 0.440 | ||
| CDK4 | cyclin-dependent kinase 4 | 0.180 | Human | |
| CCND3 | cyclin D3 | 0.139 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.090 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.041 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.032 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.014 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.014 | ||
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.014 | ||
| INSR | insulin receptor | 0.012 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.012 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.011 | ||
| CCND2 | cyclin D2 | 0.011 | ||
| STAP2 | signal transducing adaptor family member 2 | 0.011 | ||
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.010 | ||
| RUNX1 | runt-related transcription factor 1 | 0.010 |