|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
1.000
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
1.000
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
1.000
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
1.000
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
1.000
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
1.000
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
1.000
|
Fly |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
1.000
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
1.000
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
1.000
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
1.000
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
1.000
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
1.000
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
1.000
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
1.000
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
1.000
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
1.000
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
1.000
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
1.000
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
1.000
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
1.000
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
1.000
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
1.000
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
1.000
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
1.000
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
1.000
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
1.000
|
Human |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
1.000
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
1.000
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
1.000
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
1.000
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
1.000
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
1.000
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
1.000
|
Worm |
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
1.000
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
1.000
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
1.000
|
|
|
|
cell development
|
GO:0048468 |
328 |
1.000
|
Fly |
|
|
nerve development
|
GO:0021675 |
4 |
1.000
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
1.000
|
Fly |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
1.000
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
1.000
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
1.000
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
1.000
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
1.000
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
1.000
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
1.000
|
|
|
|
behavior
|
GO:0007610 |
112 |
1.000
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
1.000
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
1.000
|
Fly |
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
1.000
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
1.000
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
1.000
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
1.000
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
1.000
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
1.000
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
1.000
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
1.000
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
1.000
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
1.000
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
1.000
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
1.000
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
1.000
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
1.000
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
1.000
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
1.000
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
1.000
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
1.000
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
1.000
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
1.000
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
1 |
1.000
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
1.000
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
1.000
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
1.000
|
Fly |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
1.000
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
1.000
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
1.000
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
1.000
|
Fly |
|
|
mammary gland involution
|
GO:0060056 |
1 |
1.000
|
|
|
|
glial cell development
|
GO:0021782 |
7 |
1.000
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
1.000
|
Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
1.000
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
1.000
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
1.000
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
1.000
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
1.000
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
1.000
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
1.000
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
1.000
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
1.000
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
1.000
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
1.000
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
1.000
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
1.000
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
1.000
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
1.000
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
1.000
|
Fly |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
1.000
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
1.000
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
1.000
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
1.000
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
1.000
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
1.000
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
1.000
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
1.000
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
1.000
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
1.000
|
Worm Fly |
|
|
response to estrogen
|
GO:0043627 |
47 |
1.000
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
1.000
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
1.000
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
1.000
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
1.000
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
1.000
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
1.000
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
1.000
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
1.000
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
1.000
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
1.000
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
1.000
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
1.000
|
Human |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
1.000
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
1.000
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
1.000
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
1.000
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
1.000
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
1.000
|
Fly |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
1.000
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
1.000
|
|
|
|
stat protein import into nucleus
|
GO:0007262 |
2 |
1.000
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
1.000
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
1.000
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
1.000
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
1.000
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
1.000
|
Fly |
|
|
neural crest cell migration
|
GO:0001755 |
2 |
1.000
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
1.000
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
1.000
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
1.000
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
1.000
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
1.000
|
Human Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
1.000
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
1.000
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
1.000
|
|
|
|
immune system development
|
GO:0002520 |
195 |
1.000
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
1.000
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
1.000
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
1.000
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
1.000
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
1.000
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
1.000
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
1.000
|
Human |
|
|
positive chemotaxis
|
GO:0050918 |
33 |
1.000
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
1.000
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
1.000
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
1.000
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
1.000
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
1.000
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
1.000
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
1.000
|
Worm Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
1.000
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
1.000
|
Fly |
|
|
tube development
|
GO:0035295 |
125 |
1.000
|
Fly |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
1.000
|
Human |
|
|
growth
|
GO:0040007 |
202 |
1.000
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
1.000
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
1.000
|
Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.999
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.999
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.999
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.999
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.999
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.999
|
Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.999
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.999
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.999
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.999
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.999
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.999
|
Fly |
|
|
tor signaling
|
GO:0031929 |
39 |
0.999
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.999
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.999
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.999
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.999
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.999
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.999
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.999
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.999
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.999
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.999
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.999
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.999
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031657 |
9 |
0.999
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.999
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.999
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.999
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.999
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.999
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.999
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.999
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.998
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.998
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.998
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.998
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.998
|
Fly |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.998
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.998
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.998
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.998
|
Human |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.998
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.998
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.998
|
Fly |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.998
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.998
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.998
|
Fly |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.998
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.998
|
Fly |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.998
|
Human |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.998
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.998
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.998
|
Fly |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.998
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.998
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.998
|
Human |
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.998
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.998
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.998
|
|
|
|
body fluid secretion
|
GO:0007589 |
9 |
0.998
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.997
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.997
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.997
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.997
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.997
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.997
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.997
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.997
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.997
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.997
|
Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.997
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.997
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.997
|
Fly |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.997
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.997
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.997
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.997
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.996
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.996
|
Human |
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
19 |
0.996
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.996
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.996
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.996
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.996
|
Human |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.996
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.996
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.996
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.996
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.996
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.996
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.996
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.995
|
Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.995
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.995
|
|
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.995
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.995
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.995
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.995
|
Human |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.995
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.995
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.995
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.995
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.994
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.994
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.994
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.994
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.994
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.994
|
Human Fly |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.994
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.994
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.994
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.994
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.994
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.994
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.994
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.993
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.993
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.993
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.993
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.993
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.993
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.993
|
|
|
|
negative regulation of immature t cell proliferation
|
GO:0033087 |
1 |
0.993
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.993
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.993
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.993
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.992
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.992
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.992
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.992
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.992
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.992
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.992
|
Fly |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.992
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.992
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.992
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.992
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.992
|
|
|
|
peptidyl tyrosine autophosphorylation
|
GO:0038083 |
5 |
0.992
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.992
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.992
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.992
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.992
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.991
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.991
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.991
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.991
|
Fly |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.991
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.991
|
Fly |
|
|
developmental growth
|
GO:0048589 |
48 |
0.990
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.990
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.990
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.990
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.990
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.990
|
Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.990
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.990
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.990
|
|
|
|
schwann cell development
|
GO:0014044 |
1 |
0.990
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.989
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.988
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.988
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.988
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.988
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.987
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.987
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.987
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.986
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.986
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.986
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.986
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.986
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.986
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.986
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.986
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.986
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.985
|
Human |
|
|
memory
|
GO:0007613 |
3 |
0.985
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.985
|
|
|
|
exocrine system development
|
GO:0035272 |
7 |
0.985
|
Fly |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.985
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.985
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.985
|
Human |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.985
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.985
|
|
|
|
system process
|
GO:0003008 |
349 |
0.984
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.984
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.983
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.983
|
Worm Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.983
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.982
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.982
|
Fly |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.982
|
Fly |
|
|
single organism behavior
|
GO:0044708 |
28 |
0.982
|
Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.981
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.981
|
Worm Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.980
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.980
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.979
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.979
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.979
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.979
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.978
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.978
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.978
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.978
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.978
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.977
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.977
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.977
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.977
|
Fly |
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.976
|
Human |
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.975
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.975
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.975
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.975
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.974
|
Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.974
|
Human Fly |
|
|
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling
|
GO:0060665 |
1 |
0.974
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.974
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.974
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.973
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
12 |
0.973
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.972
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.972
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.972
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.971
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.971
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.971
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.970
|
|
|
|
immature t cell proliferation
|
GO:0033079 |
1 |
0.970
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.970
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.969
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.969
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.969
|
|
|
|
positive regulation of transcription from rna polymerase iii promoter
|
GO:0045945 |
10 |
0.966
|
Human |
|
|
keratinization
|
GO:0031424 |
2 |
0.966
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.966
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.965
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.965
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.964
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.964
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.964
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.963
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.963
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.963
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.963
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.962
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.962
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.962
|
|
|
|
mating
|
GO:0007618 |
1 |
0.960
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.959
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.958
|
Fly |
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.958
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.958
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.958
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.957
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.956
|
|
|
|
negative regulation of t cell differentiation in thymus
|
GO:0033085 |
2 |
0.956
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.956
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.956
|
|
|
|
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway
|
GO:1900238 |
2 |
0.955
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.955
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.955
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.954
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.954
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.954
|
|
|
|
neuron migration
|
GO:0001764 |
11 |
0.954
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.954
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.953
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.952
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.952
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.952
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.951
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.951
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.949
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.948
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.948
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.948
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.947
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.947
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.947
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.946
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.946
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.946
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.945
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.945
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.944
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
8 |
0.942
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.942
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.941
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.941
|
Human |
|
|
cellular response to alcohol
|
GO:0097306 |
29 |
0.941
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.940
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.939
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
5 |
0.939
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.937
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.937
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.935
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.934
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.934
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.934
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.934
|
|
|
|
regulation of positive chemotaxis
|
GO:0050926 |
14 |
0.934
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.933
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.932
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.931
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.930
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.929
|
Fly |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
13 |
0.929
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.928
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.927
|
Human |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.925
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.924
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.923
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.922
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.921
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.920
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.920
|
|
