IMP

Process View

Homo sapiens

14 genes annotated in human

Multi-species View

mitochondrial fission

GO:0000266

The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitochondrial fission"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitochondrial fission" (in gray)

Name	Description	Probability	Func Analog Organism
DNM1L	dynamin 1-like	1.000
EGFR	epidermal growth factor receptor	0.999	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.990	Human
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.888
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.883	Human
BCL2	B-cell CLL/lymphoma 2	0.881	Human
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.863
BAX	BCL2-associated X protein	0.784
BCL2L1	BCL2-like 1	0.784	Human
BAK1	BCL2-antagonist/killer 1	0.599	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.415	Human
MFN2	mitofusin 2	0.340
ZNF746	zinc finger protein 746	0.267
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.242
SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	0.210
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.208
RNF144B	ring finger protein 144B	0.158
SMCR7	Smith-Magenis syndrome chromosome region, candidate 7	0.156
FBXO7	F-box protein 7	0.133
SKA3	spindle and kinetochore associated complex subunit 3	0.123
UBASH3B	ubiquitin associated and SH3 domain containing B	0.114
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.076
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.070
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.065
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.051
RNR2	l-rRNA	0.048
SERTAD4	SERTA domain containing 4	0.044
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.043	Human
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.040
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.037
SKA2	spindle and kinetochore associated complex subunit 2	0.037
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.033
FIS1	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	0.030
BID	BH3 interacting domain death agonist	0.029
TMEM11	transmembrane protein 11	0.026
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.025
DBN1	drebrin 1	0.021
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.021
GAB2	GRB2-associated binding protein 2	0.021
DLG2	discs, large homolog 2 (Drosophila)	0.021
MUC1	mucin 1, cell surface associated	0.021
DLG4	discs, large homolog 4 (Drosophila)	0.019
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.018
VDAC1	voltage-dependent anion channel 1	0.017
TRO	trophinin	0.017
SKA1	spindle and kinetochore associated complex subunit 1	0.017
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.016
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.016
GNB5	guanine nucleotide binding protein (G protein), beta 5	0.015
BCAP31	B-cell receptor-associated protein 31	0.015
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.014
DAXX	death-domain associated protein	0.013
BAG2	BCL2-associated athanogene 2	0.013
ZFAND5	zinc finger, AN1-type domain 5	0.013
VAV3	vav 3 guanine nucleotide exchange factor	0.013
HDAC6	histone deacetylase 6	0.012
HIPK2	homeodomain interacting protein kinase 2	0.012
INSR	insulin receptor	0.012
BIK	BCL2-interacting killer (apoptosis-inducing)	0.012
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.012
HUWE1	HECT, UBA and WWE domain containing 1	0.012
HAGH	hydroxyacylglutathione hydrolase	0.011
NBR1	neighbor of BRCA1 gene 1	0.011
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.011
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.011
DLG3	discs, large homolog 3 (Drosophila)	0.011
AMBRA1	autophagy/beclin-1 regulator 1	0.011
BAD	BCL2-associated agonist of cell death	0.011
UBASH3A	ubiquitin associated and SH3 domain containing A	0.010
ZFYVE1	zinc finger, FYVE domain containing 1	0.010
ELK1	ELK1, member of ETS oncogene family	0.010
PTK6	PTK6 protein tyrosine kinase 6	0.010
UVRAG	UV radiation resistance associated gene	0.010
MKRN1	makorin ring finger protein 1	0.010