IMP

Process View

Homo sapiens

15 genes annotated in human

Multi-species View

regulation of smooth muscle cell migration

GO:0014910

Any process that modulates the frequency, rate or extent of smooth muscle cell migration.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of smooth muscle cell migration"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of smooth muscle cell migration" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	1.000
VEGFA	vascular endothelial growth factor A	1.000	Human
C1QA	complement component 1, q subcomponent, A chain	0.998	Human
EGFR	epidermal growth factor receptor	0.997
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.973
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.973
NRP1	neuropilin 1	0.952
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.942	Human
CCR5	chemokine (C-C motif) receptor 5	0.935
FN1	fibronectin 1	0.892
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.799
PLAU	plasminogen activator, urokinase	0.760
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.755	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.747
PLAT	plasminogen activator, tissue	0.720	Human
IGF2R	insulin-like growth factor 2 receptor	0.712
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.674
NCOR2	nuclear receptor corepressor 2	0.644
PXN	paxillin	0.642
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.637	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.616
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.549
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.544
BCAR1	breast cancer anti-estrogen resistance 1	0.537
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.533
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.520
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.518
CCL2	chemokine (C-C motif) ligand 2	0.516	Human
DCN	decorin	0.487
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.484
C1QC	complement component 1, q subcomponent, C chain	0.473	Human
CCL4	chemokine (C-C motif) ligand 4	0.447	Human
GRB2	growth factor receptor-bound protein 2	0.446
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.444
COL1A1	collagen, type I, alpha 1	0.364
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.305
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.303
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.246
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.239	Human
C1QB	complement component 1, q subcomponent, B chain	0.224	Human
PLAUR	plasminogen activator, urokinase receptor	0.216
THBS1	thrombospondin 1	0.211
CXCL9	chemokine (C-X-C motif) ligand 9	0.205
JDP2	Jun dimerization protein 2	0.170
GAB1	GRB2-associated binding protein 1	0.169
CCL5	chemokine (C-C motif) ligand 5	0.165
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.161
CCL8	chemokine (C-C motif) ligand 8	0.156	Human
ESRRG	estrogen-related receptor gamma	0.155
HSPG2	heparan sulfate proteoglycan 2	0.149
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.139
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.129
COL4A1	collagen, type IV, alpha 1	0.129
PDGFC	platelet derived growth factor C	0.128
IL8	interleukin 8	0.127
PPARG	peroxisome proliferator-activated receptor gamma	0.119
PLCG1	phospholipase C, gamma 1	0.106
MAPK8	mitogen-activated protein kinase 8	0.088
OSMR	oncostatin M receptor	0.088
CCL13	chemokine (C-C motif) ligand 13	0.087	Human
JAK2	Janus kinase 2	0.086
AXL	AXL receptor tyrosine kinase	0.083
APOE	apolipoprotein E	0.083
CDH5	cadherin 5, type 2 (vascular endothelium)	0.082
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.080
C1S	complement component 1, s subcomponent	0.079
CCL3	chemokine (C-C motif) ligand 3	0.078	Human
STC1	stanniocalcin 1	0.077
S100B	S100 calcium binding protein B	0.074
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.073
TGFB3	transforming growth factor, beta 3	0.073
IL1B	interleukin 1, beta	0.071
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.070
ITGB1BP3	integrin beta 1 binding protein 3	0.065
CXCL12	chemokine (C-X-C motif) ligand 12	0.064
SYNRG	synergin, gamma	0.064
ADAM12	ADAM metallopeptidase domain 12	0.064
ENG	endoglin	0.062
BCL2L1	BCL2-like 1	0.060
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.059
TF	transferrin	0.057
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.057
PARVA	parvin, alpha	0.056
IGF1R	insulin-like growth factor 1 receptor	0.055
TIMP3	TIMP metallopeptidase inhibitor 3	0.054
IGF1	insulin-like growth factor 1 (somatomedin C)	0.053
LDLR	low density lipoprotein receptor	0.052
HNF4A	hepatocyte nuclear factor 4, alpha	0.051
LAT	linker for activation of T cells	0.049
IGF2	insulin-like growth factor 2 (somatomedin A)	0.048	Human
ATF5	activating transcription factor 5	0.047
STAB1	stabilin 1	0.047
NNMT	nicotinamide N-methyltransferase	0.046
MEF2A	myocyte enhancer factor 2A	0.046
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.045
PGF	placental growth factor	0.044	Human
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.044
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.042
LTBP2	latent transforming growth factor beta binding protein 2	0.041
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.041	Rat
CCR1	chemokine (C-C motif) receptor 1	0.040
CCL7	chemokine (C-C motif) ligand 7	0.040	Human
VEGFC	vascular endothelial growth factor C	0.040	Human
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.040
PTPRB	protein tyrosine phosphatase, receptor type, B	0.039
INHBA	inhibin, beta A	0.039
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.038
NOV	nephroblastoma overexpressed gene	0.038
VCAM1	vascular cell adhesion molecule 1	0.038
IL6	interleukin 6 (interferon, beta 2)	0.038
KITLG	KIT ligand	0.038
DDIT3	DNA-damage-inducible transcript 3	0.036
TTR	transthyretin	0.036
COL1A2	collagen, type I, alpha 2	0.036
GAB2	GRB2-associated binding protein 2	0.035
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.034
CXCL3	chemokine (C-X-C motif) ligand 3	0.033
TFPI2	tissue factor pathway inhibitor 2	0.033
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.033
IGFBP3	insulin-like growth factor binding protein 3	0.033
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.032
CCL20	chemokine (C-C motif) ligand 20	0.030	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.030
IRS1	insulin receptor substrate 1	0.030
MEF2C	myocyte enhancer factor 2C	0.030
CUEDC2	CUE domain containing 2	0.030
OCRL	oculocerebrorenal syndrome of Lowe	0.030
IGFBP5	insulin-like growth factor binding protein 5	0.029
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.028	Rat
MARCO	macrophage receptor with collagenous structure	0.027
PDGFA	platelet-derived growth factor alpha polypeptide	0.027
CXCL2	chemokine (C-X-C motif) ligand 2	0.026
CXCL13	chemokine (C-X-C motif) ligand 13	0.026
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.025
CCL19	chemokine (C-C motif) ligand 19	0.025	Human
DARC	Duffy blood group, chemokine receptor	0.025
RICTOR	RPTOR independent companion of MTOR, complex 2	0.025
PTK2	PTK2 protein tyrosine kinase 2	0.025	Rat
COL5A1	collagen, type V, alpha 1	0.024
COL4A2	collagen, type IV, alpha 2	0.024
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.023
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.022
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.022
ANGPTL2	angiopoietin-like 2	0.022
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.021
SOCS3	suppressor of cytokine signaling 3	0.021
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.020
DPP4	dipeptidyl-peptidase 4	0.019
SOS1	son of sevenless homolog 1 (Drosophila)	0.019
SLAMF8	SLAM family member 8	0.019
COL6A2	collagen, type VI, alpha 2	0.019
SELE	selectin E	0.019
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.018
LAMA4	laminin, alpha 4	0.018
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.018
THBS2	thrombospondin 2	0.018
CSF1	colony stimulating factor 1 (macrophage)	0.018
FLNA	filamin A, alpha	0.017
NRP2	neuropilin 2	0.017
PTRF	polymerase I and transcript release factor	0.016
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.016
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.015
ANGPTL4	angiopoietin-like 4	0.015
MMP19	matrix metallopeptidase 19	0.015
LRRC32	leucine rich repeat containing 32	0.015
COL6A1	collagen, type VI, alpha 1	0.015
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.015
PDIA3	protein disulfide isomerase family A, member 3	0.015
CCL11	chemokine (C-C motif) ligand 11	0.015	Human
TGFB1	transforming growth factor, beta 1	0.014
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.014
CXCL5	chemokine (C-X-C motif) ligand 5	0.014
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.014
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.014
EEA1	early endosome antigen 1	0.014
CCL21	chemokine (C-C motif) ligand 21	0.014
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.013
CD83	CD83 molecule	0.013
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.013
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.013
CD248	CD248 molecule, endosialin	0.013
RGS16	regulator of G-protein signaling 16	0.013
ZYX	zyxin	0.013
TNC	tenascin C	0.013
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.013	Human
THY1	Thy-1 cell surface antigen	0.013
ORM1	orosomucoid 1	0.012
KNG1	kininogen 1	0.012
ICAM1	intercellular adhesion molecule 1	0.012
FST	follistatin	0.012
COL3A1	collagen, type III, alpha 1	0.012
GNLY	granulysin	0.012
EHD1	EH-domain containing 1	0.012
SPRR2A	small proline-rich protein 2A	0.012
CD163	CD163 molecule	0.012
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.012
CXCL14	chemokine (C-X-C motif) ligand 14	0.012
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.012
MAP2	microtubule-associated protein 2	0.011
DDR2	discoidin domain receptor tyrosine kinase 2	0.011
AMBRA1	autophagy/beclin-1 regulator 1	0.011
CCR7	chemokine (C-C motif) receptor 7	0.011
PTHLH	parathyroid hormone-like hormone	0.011
CCR3	chemokine (C-C motif) receptor 3	0.011
IGFBP4	insulin-like growth factor binding protein 4	0.011	Human
COLEC12	collectin sub-family member 12	0.011
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.011
PXDN	peroxidasin homolog (Drosophila)	0.011
SRPX	sushi-repeat containing protein, X-linked	0.011
IL32	interleukin 32	0.011
PCDH17	protocadherin 17	0.011
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.010	Human
COL18A1	collagen, type XVIII, alpha 1	0.010
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.010
POSTN	periostin, osteoblast specific factor	0.010
IL10	interleukin 10	0.010
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.010
TLN1	talin 1	0.010
FRZB	frizzled-related protein	0.010
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.010