Homo sapiens

21 known processes

FBN1

fibrillin 1

(Aliases: MFS1,SSKS,SGS,WMS,MASS,OCTD,FBN)

FBN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
elastic fiber assembly GO:0048251 3 0.996
extracellular matrix organization GO:0030198 41 0.980
extracellular structure organization GO:0043062 41 0.978
circulatory system development GO:0072359 262 0.963
positive regulation of mesenchymal stem cell differentiation GO:2000741 4 0.960
regulation of mesenchymal stem cell proliferation GO:1902460 1 0.959
skeletal system development GO:0001501 79 0.943
cardiovascular system development GO:0072358 262 0.927
cartilage development GO:0051216 31 0.908
positive regulation of locomotion GO:0040017 186 0.834
enzyme linked receptor protein signaling pathway GO:0007167 303 0.808
Mouse
multicellular organismal metabolic process GO:0044236 34 0.801
ossification GO:0001503 121 0.799
peptidyl tyrosine modification GO:0018212 170 0.793
positive regulation of developmental process GO:0051094 314 0.784
negative regulation of endodermal cell differentiation GO:1903225 2 0.775
positive regulation of stem cell differentiation GO:2000738 29 0.771
collagen fibril organization GO:0030199 10 0.769
transforming growth factor beta activation GO:0036363 1 0.753
regulation of cell adhesion GO:0030155 166 0.718
mesenchymal stem cell proliferation GO:0097168 1 0.678
regulation of cell motility GO:2000145 299 0.662
connective tissue development GO:0061448 39 0.616
negative regulation of multicellular organismal process GO:0051241 317 0.565
epithelium development GO:0060429 227 0.556
positive regulation of mesenchymal stem cell proliferation GO:1902462 1 0.530
system process GO:0003008 349 0.486
biological adhesion GO:0022610 331 0.485
blood vessel development GO:0001568 172 0.465
endodermal cell differentiation GO:0035987 31 0.463
cellular response to growth factor stimulus GO:0071363 197 0.455
Mouse
cellular component morphogenesis GO:0032989 314 0.446
cell adhesion GO:0007155 325 0.420
positive regulation of cell motility GO:2000147 177 0.399
regulation of locomotion GO:0040012 329 0.394
negative regulation of chondrocyte differentiation GO:0032331 5 0.393
anatomical structure formation involved in morphogenesis GO:0048646 284 0.389
detection of mechanical stimulus GO:0050982 4 0.384
cellular macromolecular complex assembly GO:0034622 324 0.370
negative regulation of cell differentiation GO:0045596 171 0.366
muscle structure development GO:0061061 98 0.350
positive regulation of cellular component movement GO:0051272 181 0.338
cellular response to oxygen containing compound GO:1901701 276 0.332
negative regulation of developmental process GO:0051093 247 0.331
tube development GO:0035295 125 0.313
regulation of ossification GO:0030278 58 0.301
negative regulation of gastrulation GO:2000542 4 0.295
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.284
positive regulation of cell differentiation GO:0045597 211 0.266
organ morphogenesis GO:0009887 147 0.264
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.262
Mouse
blood vessel morphogenesis GO:0048514 162 0.258
glomerular basement membrane development GO:0032836 3 0.256
cell substrate adhesion GO:0031589 132 0.254
positive regulation of cell adhesion GO:0045785 84 0.246
sensory perception GO:0007600 103 0.243
embryo development GO:0009790 123 0.235
regulation of cartilage development GO:0061035 12 0.227
sprouting angiogenesis GO:0002040 29 0.219
striated muscle tissue development GO:0014706 59 0.217
nervous system development GO:0007399 293 0.216
negative regulation of cartilage development GO:0061037 5 0.208
response to wounding GO:0009611 168 0.208
sensory perception of light stimulus GO:0050953 35 0.204
positive regulation of cellular amine metabolic process GO:0033240 7 0.204
negative regulation of embryonic development GO:0045992 4 0.203
cell matrix adhesion GO:0007160 85 0.203
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.202
regulation of cell differentiation GO:0045595 393 0.201
endoderm formation GO:0001706 33 0.200
single organismal cell cell adhesion GO:0016337 148 0.194
vasculature development GO:0001944 181 0.192
endoderm development GO:0007492 33 0.188
digestive tract morphogenesis GO:0048546 56 0.181
post embryonic development GO:0009791 2 0.178
Worm
regulation of anatomical structure size GO:0090066 101 0.177
single organism membrane organization GO:0044802 268 0.175
cellular amine metabolic process GO:0044106 41 0.173
tissue morphogenesis GO:0048729 96 0.173
bone trabecula formation GO:0060346 1 0.172
ameboidal type cell migration GO:0001667 135 0.162
multicellular organismal macromolecule metabolic process GO:0044259 29 0.149
regulation of cellular amino acid metabolic process GO:0006521 6 0.146
muscle organ development GO:0007517 56 0.143
positive regulation of protein phosphorylation GO:0001934 313 0.142
response to oxygen containing compound GO:1901700 369 0.139
osteoblast differentiation GO:0001649 92 0.139
regulation of stem cell differentiation GO:2000736 56 0.139
soft palate development GO:0060023 3 0.137
embryonic skeletal joint morphogenesis GO:0060272 2 0.131
extracellular matrix assembly GO:0085029 5 0.131
circulatory system process GO:0003013 113 0.127
cell morphogenesis involved in differentiation GO:0000904 144 0.126
negative regulation of cell migration GO:0030336 102 0.124
regulation of cell migration GO:0030334 289 0.120
response to abiotic stimulus GO:0009628 336 0.118
mesenchymal stem cell differentiation GO:0072497 8 0.118
regulation of anatomical structure morphogenesis GO:0022603 286 0.117
negative regulation of cell adhesion GO:0007162 64 0.116
corticospinal tract morphogenesis GO:0021957 1 0.113
heparin biosynthetic process GO:0030210 1 0.113
integrin mediated signaling pathway GO:0007229 32 0.112
cellular protein complex assembly GO:0043623 188 0.109
bone trabecula morphogenesis GO:0061430 1 0.108
cell development GO:0048468 328 0.108
cellular amino acid metabolic process GO:0006520 116 0.105
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.105
Mouse
collagen metabolic process GO:0032963 28 0.102
apoptotic signaling pathway GO:0097190 268 0.099
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.097
glial cell migration GO:0008347 4 0.096
cellular ketone metabolic process GO:0042180 80 0.095
single organism cell adhesion GO:0098602 179 0.095
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.094
cellular response to amino acid stimulus GO:0071230 12 0.094
lung growth GO:0060437 2 0.094
sensory perception of mechanical stimulus GO:0050954 37 0.091
basement membrane organization GO:0071711 3 0.090
plasma membrane organization GO:0007009 115 0.089
negative regulation of blood vessel morphogenesis GO:2000181 41 0.088
wound healing GO:0042060 115 0.088
sensory organ development GO:0007423 52 0.083
muscle tissue development GO:0060537 62 0.079
regulation of proteolysis GO:0030162 293 0.077
regeneration GO:0031099 4 0.076
immune response GO:0006955 307 0.075
negative regulation of positive chemotaxis GO:0050928 1 0.075
cell type specific apoptotic process GO:0097285 125 0.072
cytokine production GO:0001816 247 0.072
endomembrane system organization GO:0010256 196 0.071
regulation of cellular amine metabolic process GO:0033238 11 0.071
endothelial cell cell adhesion GO:0071603 1 0.070
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.069
regulation of cellular ketone metabolic process GO:0010565 50 0.068
negative regulation of locomotion GO:0040013 118 0.065
erk1 and erk2 cascade GO:0070371 104 0.064
actomyosin structure organization GO:0031032 59 0.063
regulation of cell morphogenesis GO:0022604 153 0.062
sulfur compound biosynthetic process GO:0044272 38 0.062
chondrocyte differentiation GO:0002062 17 0.061
positive regulation of protein kinase activity GO:0045860 190 0.061
detection of stimulus GO:0051606 85 0.061
epithelial cell migration GO:0010631 119 0.060
regulation of wnt signaling pathway GO:0030111 123 0.060
negative regulation of epithelial cell migration GO:0010633 38 0.059
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.058
neurogenesis GO:0022008 169 0.058
cellular response to endogenous stimulus GO:0071495 336 0.057
Mouse
generation of neurons GO:0048699 152 0.056
neurological system process GO:0050877 163 0.056
positive regulation of exocytosis GO:0045921 35 0.056
regulation of actin filament polymerization GO:0030833 50 0.056
negative regulation of cell motility GO:2000146 104 0.056
regulation of protein kinase activity GO:0045859 289 0.055
actin cytoskeleton organization GO:0030036 207 0.054
membrane organization GO:0061024 292 0.054
extracellular fibril organization GO:0043206 7 0.054
amine metabolic process GO:0009308 44 0.053
positive regulation of cellular component organization GO:0051130 376 0.053
embryonic morphogenesis GO:0048598 85 0.053
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.053
Mouse
response to growth factor GO:0070848 205 0.052
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.052
positive regulation of stem cell proliferation GO:2000648 10 0.052
striated muscle cell differentiation GO:0051146 43 0.050
regulation of system process GO:0044057 101 0.050
negative regulation of apoptotic signaling pathway GO:2001234 97 0.049
regulation of vasculature development GO:1901342 97 0.048
stress fiber assembly GO:0043149 40 0.048
positive regulation of heterotypic cell cell adhesion GO:0034116 8 0.048
regulation of angiogenesis GO:0045765 92 0.048
inner ear morphogenesis GO:0042472 4 0.047
transforming growth factor beta production GO:0071604 14 0.047
negative regulation of angiogenesis GO:0016525 39 0.047
protein polymerization GO:0051258 71 0.047
regulation of chondrocyte differentiation GO:0032330 9 0.047
carbohydrate derivative biosynthetic process GO:1901137 207 0.046
cell projection morphogenesis GO:0048858 129 0.046
mucopolysaccharide metabolic process GO:1903510 27 0.046
morphogenesis of an epithelium GO:0002009 60 0.046
cerebral cortex cell migration GO:0021795 3 0.046
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.046
trabecula morphogenesis GO:0061383 2 0.046
regulation of peptidase activity GO:0052547 180 0.046
positive regulation of transferase activity GO:0051347 227 0.046
ras protein signal transduction GO:0007265 73 0.045
actin filament bundle organization GO:0061572 54 0.045
positive regulation of phosphorylation GO:0042327 394 0.045
regulation of protein transport GO:0051223 213 0.045
heart development GO:0007507 95 0.045
actin polymerization or depolymerization GO:0008154 56 0.044
morphogenesis of a branching structure GO:0001763 21 0.044
rho protein signal transduction GO:0007266 26 0.044
regulation of kinase activity GO:0043549 314 0.044
single organism cellular localization GO:1902580 332 0.044
regulation of cellular response to growth factor stimulus GO:0090287 76 0.043
Mouse
angiogenesis GO:0001525 147 0.043
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.043
growth GO:0040007 202 0.043
regulation of cellular component movement GO:0051270 334 0.042
blood circulation GO:0008015 113 0.041
epithelium migration GO:0090132 119 0.041
regulation of canonical wnt signaling pathway GO:0060828 88 0.041
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.041
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.040
Mouse
positive regulation of cell cell adhesion GO:0022409 22 0.040
positive regulation of kinase activity GO:0033674 204 0.040
positive regulation of cell migration GO:0030335 172 0.040
negative regulation of protein metabolic process GO:0051248 391 0.039
blood vessel endothelial cell migration GO:0043534 42 0.039
response to light stimulus GO:0009416 87 0.039
multicellular organismal aging GO:0010259 3 0.038
response to metal ion GO:0010038 84 0.038
actin filament organization GO:0007015 128 0.037
positive regulation of fibroblast migration GO:0010763 3 0.037
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.037
protein localization to organelle GO:0033365 280 0.037
regulation of protein secretion GO:0050708 86 0.036
cellular response to organonitrogen compound GO:0071417 124 0.036
skeletal system morphogenesis GO:0048705 24 0.036
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.036
embryonic camera type eye development GO:0031076 2 0.036
cellular component assembly involved in morphogenesis GO:0010927 73 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
regulation of osteoblast differentiation GO:0045667 38 0.035
actin filament bundle assembly GO:0051017 54 0.034
visual perception GO:0007601 27 0.034
regulation of cell cell adhesion GO:0022407 57 0.034
response to amino acid GO:0043200 14 0.034
positive regulation of angiogenesis GO:0045766 51 0.033
negative regulation of immune system process GO:0002683 136 0.032
response to mercury ion GO:0046689 4 0.032
platelet activation GO:0030168 44 0.032
regulation of epithelial cell migration GO:0010632 93 0.032
skeletal muscle tissue development GO:0007519 24 0.032
muscle system process GO:0003012 81 0.031
regulation of erk1 and erk2 cascade GO:0070372 99 0.031
positive regulation of cell proliferation GO:0008284 301 0.031
regulation of receptor mediated endocytosis GO:0048259 32 0.031
neuronal glial interaction involved in cerebral cortex radial glia guided migration GO:0021812 1 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.031
optokinetic behavior GO:0007634 1 0.031
response to calcium ion GO:0051592 46 0.031
skeletal muscle satellite cell proliferation GO:0014841 1 0.031
muscle contraction GO:0006936 73 0.030
striated muscle contraction GO:0006941 52 0.030
sensory perception of sound GO:0007605 37 0.030
chondroitin sulfate proteoglycan metabolic process GO:0050654 10 0.030
protein modification by small protein conjugation GO:0032446 342 0.030
positive regulation of wnt signaling pathway GO:0030177 54 0.029
regulation of body fluid levels GO:0050878 99 0.029
response to uv b GO:0010224 10 0.029
cellular response to reactive oxygen species GO:0034614 50 0.029
taxis GO:0042330 157 0.029
heart morphogenesis GO:0003007 48 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.029
actin filament based process GO:0030029 224 0.028
tissue regeneration GO:0042246 3 0.028
regulation of cell development GO:0060284 161 0.028
actin filament based movement GO:0030048 17 0.028
response to hormone GO:0009725 175 0.028
heterotypic cell cell adhesion GO:0034113 28 0.028
cellular response to nitrogen compound GO:1901699 144 0.028
positive regulation of cell development GO:0010720 92 0.028
substrate adhesion dependent cell spreading GO:0034446 41 0.027
response to cytokine GO:0034097 232 0.027
protein ubiquitination GO:0016567 314 0.027
cell activation GO:0001775 213 0.027
response to acid chemical GO:0001101 66 0.027
innate immune response GO:0045087 178 0.026
mesenchymal cell development GO:0014031 50 0.026
regulation of immune response GO:0050776 201 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
maintenance of location GO:0051235 112 0.026
Mouse
sphingolipid mediated signaling pathway GO:0090520 1 0.026
negative regulation of response to external stimulus GO:0032102 83 0.026
detection of external stimulus GO:0009581 15 0.026
response to transforming growth factor beta GO:0071559 94 0.026
Mouse
secretion by cell GO:0032940 226 0.025
negative regulation of chemotaxis GO:0050922 13 0.025
negative regulation of cell death GO:0060548 345 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
transmembrane transport GO:0055085 399 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
cerebral cortex radially oriented cell migration GO:0021799 1 0.025
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.024
wound healing spreading of cells GO:0044319 8 0.024
retinal ganglion cell axon guidance GO:0031290 2 0.024
regulation of transferase activity GO:0051338 355 0.024
regulation of actin filament based process GO:0032970 141 0.024
heparin metabolic process GO:0030202 1 0.024
muscle cell development GO:0055001 29 0.023
embryonic organ development GO:0048568 36 0.023
female gamete generation GO:0007292 2 0.023
positive regulation of transport GO:0051050 336 0.023
regulation of mesenchymal stem cell differentiation GO:2000739 6 0.023
response to fibroblast growth factor GO:0071774 39 0.023
respiratory tube development GO:0030323 20 0.023
regulation of protein complex assembly GO:0043254 147 0.023
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.023
response to reactive oxygen species GO:0000302 61 0.023
embryonic skeletal joint development GO:0072498 2 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
mesenchymal cell differentiation GO:0048762 52 0.022
wnt signaling pathway GO:0016055 156 0.022
positive regulation of endocytosis GO:0045807 42 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
nitrogen compound transport GO:0071705 191 0.022
mitotic cell cycle process GO:1903047 286 0.022
regulation of blood circulation GO:1903522 59 0.022
regulation of response to external stimulus GO:0032101 222 0.022
regulation of endocytosis GO:0030100 72 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.021
kidney epithelium development GO:0072073 25 0.021
regulation of satellite cell proliferation GO:0014842 1 0.021
urogenital system development GO:0001655 65 0.021
axis elongation GO:0003401 4 0.021
peptidyl serine modification GO:0018209 106 0.021
myosin filament assembly GO:0031034 2 0.021
chondroitin sulfate metabolic process GO:0030204 7 0.021
determination of adult lifespan GO:0008340 2 0.021
response to bacterium GO:0009617 144 0.021
response to drug GO:0042493 81 0.021
axon regeneration GO:0031103 1 0.021
protein maturation GO:0051604 233 0.020
regulation of gastrulation GO:0010470 12 0.020
vesicle organization GO:0016050 62 0.020
synaptic transmission cholinergic GO:0007271 2 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
activation of protein kinase activity GO:0032147 90 0.020
positive regulation of cell substrate adhesion GO:0010811 37 0.020
receptor metabolic process GO:0043112 81 0.020
cellular component disassembly GO:0022411 92 0.020
protein catabolic process GO:0030163 325 0.020
mapk cascade GO:0000165 288 0.020
regulation of exocytosis GO:0017157 46 0.020
regulation of collagen metabolic process GO:0010712 15 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
response to lipid GO:0033993 206 0.020
protein secretion GO:0009306 98 0.020
behavior GO:0007610 112 0.020
positive regulation of osteoblast proliferation GO:0033690 3 0.020
epidermal growth factor receptor signaling pathway GO:0007173 39 0.020
regulation of vesicle mediated transport GO:0060627 130 0.019
cellular response to radiation GO:0071478 65 0.019
negative regulation of immune response GO:0050777 40 0.019
regulation of endothelial cell migration GO:0010594 67 0.019
organelle assembly GO:0070925 176 0.019
cellular protein catabolic process GO:0044257 261 0.019
protein processing GO:0016485 226 0.019
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
secretion GO:0046903 254 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
cartilage condensation GO:0001502 1 0.019
vesicle mediated transport GO:0016192 371 0.019
striated muscle myosin thick filament assembly GO:0071688 2 0.019
sulfur compound metabolic process GO:0006790 101 0.019
response to oxygen levels GO:0070482 100 0.019
chemical homeostasis GO:0048878 306 0.018
zymogen activation GO:0031638 70 0.018
tissue migration GO:0090130 119 0.018
cerebral cortex development GO:0021987 10 0.018
maintenance of protein location GO:0045185 57 0.018
Mouse
chemotaxis GO:0006935 157 0.018
neuron projection regeneration GO:0031102 1 0.018
response to organic cyclic compound GO:0014070 204 0.018
receptor mediated endocytosis GO:0006898 84 0.018
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.018
cell morphogenesis GO:0000902 296 0.018
anatomical structure homeostasis GO:0060249 100 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
organonitrogen compound biosynthetic process GO:1901566 200 0.018
negative regulation of transport GO:0051051 176 0.018
metencephalon development GO:0022037 2 0.018
neuromuscular junction development GO:0007528 3 0.018
cation homeostasis GO:0055080 189 0.018
gastrulation GO:0007369 51 0.018
regulation of biomineral tissue development GO:0070167 31 0.018
sequestering of extracellular ligand from receptor GO:0035581 3 0.018
Mouse
embryonic organ morphogenesis GO:0048562 24 0.018
regulation of protein ubiquitination GO:0031396 95 0.018
cellular response to decreased oxygen levels GO:0036294 51 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
regulation of cell substrate adhesion GO:0010810 68 0.017
cell part morphogenesis GO:0032990 137 0.017
neuron migration GO:0001764 11 0.017
epiboly involved in wound healing GO:0090505 8 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
response to steroid hormone GO:0048545 80 0.017
protein activation cascade GO:0072376 22 0.017
regulation of chemotaxis GO:0050920 74 0.017
regulation of mapk cascade GO:0043408 262 0.017
positive regulation of endothelial cell migration GO:0010595 39 0.017
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
tube morphogenesis GO:0035239 95 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.017
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.017
positive regulation of epithelial cell migration GO:0010634 55 0.016
response to radiation GO:0009314 151 0.016
glycosaminoglycan metabolic process GO:0030203 35 0.016
protein localization to nucleus GO:0034504 136 0.016
positive regulation of osteoblast differentiation GO:0045669 23 0.016
establishment or maintenance of cell polarity GO:0007163 31 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
positive regulation of axon extension GO:0045773 4 0.016
stem cell differentiation GO:0048863 93 0.016
regulation of secretion by cell GO:1903530 177 0.016
peptide hormone secretion GO:0030072 50 0.016
skin development GO:0043588 76 0.016
response to uv GO:0009411 73 0.016
negative regulation of protein modification process GO:0031400 200 0.016
cardiac muscle contraction GO:0060048 34 0.016
sensory organ morphogenesis GO:0090596 21 0.015
positive regulation of chemotaxis GO:0050921 57 0.015
ear development GO:0043583 14 0.015
tooth mineralization GO:0034505 6 0.015
striated muscle cell development GO:0055002 27 0.015
positive regulation of secretion GO:0051047 116 0.015
endothelial cell apoptotic process GO:0072577 26 0.015
response to decreased oxygen levels GO:0036293 96 0.015
visual behavior GO:0007632 2 0.015
cellular response to light stimulus GO:0071482 34 0.015
regulation of epithelial to mesenchymal transition GO:0010717 37 0.015
negative regulation of vasculature development GO:1901343 43 0.015
regulation of endodermal cell differentiation GO:1903224 3 0.015
positive regulation of vasoconstriction GO:0045907 3 0.015
hindbrain development GO:0030902 3 0.015
activation of immune response GO:0002253 114 0.014
response to mechanical stimulus GO:0009612 51 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.014
regulation of protein binding GO:0043393 66 0.014
morphogenesis of an epithelial sheet GO:0002011 12 0.014
regulation of behavior GO:0050795 82 0.014
positive regulation of immune system process GO:0002684 283 0.014
lipid transport GO:0006869 90 0.014
cellular response to lipid GO:0071396 127 0.014
cellular response to oxygen levels GO:0071453 55 0.014
regulation of neuron projection development GO:0010975 57 0.014
protein localization to cell surface GO:0034394 28 0.014
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.014
cellular response to oxidative stress GO:0034599 85 0.014
anterior posterior axis specification GO:0009948 2 0.014
negative regulation of granulocyte chemotaxis GO:0071623 2 0.014
response to nitrogen compound GO:1901698 184 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.013
segmentation GO:0035282 4 0.013
embryonic viscerocranium morphogenesis GO:0048703 1 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
extracellular matrix disassembly GO:0022617 16 0.013
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.013
formation of primary germ layer GO:0001704 42 0.013
response to external biotic stimulus GO:0043207 261 0.013
neuron projection development GO:0031175 106 0.013
protein targeting GO:0006605 187 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
skeletal muscle organ development GO:0060538 26 0.013
response to axon injury GO:0048678 1 0.013
eye development GO:0001654 42 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
protein oligomerization GO:0051259 173 0.013
ureteric bud development GO:0001657 13 0.013
cell projection organization GO:0030030 252 0.013
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.013
regulation of cellular component size GO:0032535 82 0.012

FBN1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.638
Human
sensory system disease DOID:0050155 203 0.317
nervous system disease DOID:863 431 0.317
retinal disease DOID:5679 118 0.172
eye and adnexa disease DOID:1492 150 0.172
eye disease DOID:5614 149 0.172
heart disease DOID:114 68 0.128
cardiovascular system disease DOID:1287 106 0.128
muscular disease DOID:0080000 114 0.117
Human
muscle tissue disease DOID:66 113 0.117
Human
connective tissue disease DOID:65 109 0.116
retinal degeneration DOID:8466 89 0.084
collagen disease DOID:854 9 0.066
ehlers danlos syndrome DOID:13359 9 0.066
degeneration of macula and posterior pole DOID:2007 17 0.057
macular degeneration DOID:4448 20 0.057
age related macular degeneration DOID:10871 17 0.045
osteochondrodysplasia DOID:2256 35 0.029
osteogenesis imperfecta DOID:12347 13 0.029
bone development disease DOID:0080006 55 0.029
bone disease DOID:0080001 88 0.029
myopathy DOID:423 104 0.026
distal arthrogryposis DOID:0050646 9 0.013
Human