IMP
Process View
negative regulation of neurotrophin trk receptor signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of neurotrophin trk receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.819 | ||
| RLN3 | relaxin 3 | 0.817 | ||
| DNM2 | dynamin 2 | 0.625 | ||
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.324 | Mouse | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.289 | ||
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.216 | ||
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.208 | ||
| ARRB1 | arrestin, beta 1 | 0.201 | ||
| ZNF512B | zinc finger protein 512B | 0.133 | ||
| BLNK | B-cell linker | 0.125 | ||
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.103 | Mouse | |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.091 | ||
| SSR1 | signal sequence receptor, alpha | 0.069 | ||
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.055 | ||
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.051 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.036 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.030 | ||
| CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.028 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.026 | ||
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 0.026 | ||
| ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.026 | ||
| EGFR | epidermal growth factor receptor | 0.025 | ||
| C3 | complement component 3 | 0.023 | ||
| ELANE | elastase, neutrophil expressed | 0.023 | ||
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.022 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.022 | ||
| FBN1 | fibrillin 1 | 0.019 | ||
| EDNRB | endothelin receptor type B | 0.019 | ||
| GSDMB | gasdermin B | 0.019 | ||
| RET | ret proto-oncogene | 0.018 | ||
| REPS2 | RALBP1 associated Eps domain containing 2 | 0.018 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.018 | ||
| PPL | periplakin | 0.017 | ||
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.017 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.015 | ||
| DDN | dendrin | 0.014 | ||
| SH2B2 | SH2B adaptor protein 2 | 0.014 | ||
| TFPI2 | tissue factor pathway inhibitor 2 | 0.014 | ||
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.013 | ||
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.012 | ||
| RAB7A | RAB7A, member RAS oncogene family | 0.012 | ||
| CRIP2 | cysteine-rich protein 2 | 0.012 | ||
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.012 | ||
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.011 | ||
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | 0.011 | ||
| SH3GL3 | SH3-domain GRB2-like 3 | 0.011 | ||
| SDC2 | syndecan 2 | 0.011 | ||
| LYZ | lysozyme | 0.011 | ||
| STC1 | stanniocalcin 1 | 0.011 | ||
| SYNJ2 | synaptojanin 2 | 0.011 | ||
| AGTR1 | angiotensin II receptor, type 1 | 0.011 | Human | |
| LAMC3 | laminin, gamma 3 | 0.010 | ||
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | 0.010 | ||
| REN | renin | 0.010 | ||
| DUSP6 | dual specificity phosphatase 6 | 0.010 | ||
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.010 | Human | |
| PDCD6IP | programmed cell death 6 interacting protein | 0.010 |