Homo sapiens

146 known processes

HNF1B

HNF1 homeobox B

(Aliases: HNF1beta,FJHN,TCF2,HPC11,VHNF1,MODY5,HNF2,LFB3,LF-B3)

HNF1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of hormone levels GO:0010817 125 0.625
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.612
Mouse
neuron fate commitment GO:0048663 2 0.448
amide transport GO:0042886 76 0.446
Human Mouse
cellular ketone metabolic process GO:0042180 80 0.397
regulation of cellular ketone metabolic process GO:0010565 50 0.394
regulation of kidney size GO:0035564 2 0.357
anion transport GO:0006820 161 0.355
epithelium development GO:0060429 227 0.335
secretion GO:0046903 254 0.327
Human Mouse
embryonic morphogenesis GO:0048598 85 0.311
Zebrafish Mouse
nitrogen compound transport GO:0071705 191 0.310
Human Mouse
hormone transport GO:0009914 68 0.299
Human Mouse
cellular amine metabolic process GO:0044106 41 0.299
lipid metabolic process GO:0006629 381 0.294
regulation of cell differentiation GO:0045595 393 0.293
Mouse
epithelial cell differentiation GO:0030855 141 0.286
Zebrafish Mouse
circulatory system development GO:0072359 262 0.273
peptide hormone secretion GO:0030072 50 0.256
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.255
cell cell signaling GO:0007267 155 0.253
Human Mouse
urate transport GO:0015747 3 0.249
organ morphogenesis GO:0009887 147 0.245
cardiovascular system development GO:0072358 262 0.243
response to oxygen containing compound GO:1901700 369 0.229
Mouse
cellular amino acid metabolic process GO:0006520 116 0.227
forebrain generation of neurons GO:0021872 3 0.224
peptide secretion GO:0002790 51 0.221
Human Mouse
regulation of cellular component biogenesis GO:0044087 281 0.216
cell projection organization GO:0030030 252 0.208
endocrine system development GO:0035270 26 0.206
post embryonic development GO:0009791 2 0.204
cellular lipid metabolic process GO:0044255 303 0.201
regulation of cellular amine metabolic process GO:0033238 11 0.200
regulation of thyroid hormone generation GO:2000609 2 0.197
monocarboxylic acid metabolic process GO:0032787 185 0.192
kidney development GO:0001822 53 0.187
cranial nerve development GO:0021545 4 0.182
cellular component morphogenesis GO:0032989 314 0.180
secretion by cell GO:0032940 226 0.180
Human Mouse
regulation of secretion by cell GO:1903530 177 0.178
positive regulation of developmental process GO:0051094 314 0.172
endocrine pancreas development GO:0031018 11 0.172
chemical homeostasis GO:0048878 306 0.170
Human
organic acid biosynthetic process GO:0016053 97 0.160
cellular homeostasis GO:0019725 196 0.157
transmembrane transport GO:0055085 399 0.155
regulation of cell development GO:0060284 161 0.150
Mouse
regulation of secretion GO:0051046 194 0.148
carboxylic acid biosynthetic process GO:0046394 97 0.147
positive regulation of cellular component organization GO:0051130 376 0.146
hormone secretion GO:0046879 65 0.146
Human Mouse
inner ear morphogenesis GO:0042472 4 0.144
Zebrafish
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.141
negative regulation of developmental process GO:0051093 247 0.140
Mouse
pattern specification involved in kidney development GO:0061004 1 0.140
anatomical structure formation involved in morphogenesis GO:0048646 284 0.140
Zebrafish Mouse
cell morphogenesis GO:0000902 296 0.139
positive regulation of cellular amine metabolic process GO:0033240 7 0.139
positive regulation of cell proliferation GO:0008284 301 0.138
small gtpase mediated signal transduction GO:0007264 78 0.135
response to organonitrogen compound GO:0010243 156 0.135
tissue morphogenesis GO:0048729 96 0.134
Zebrafish Mouse
organonitrogen compound biosynthetic process GO:1901566 200 0.130
regulation of metanephros size GO:0035566 1 0.129
positive regulation of cell differentiation GO:0045597 211 0.124
regulation of peptide hormone secretion GO:0090276 41 0.121
signal release GO:0023061 70 0.120
Human Mouse
tube morphogenesis GO:0035239 95 0.120
Zebrafish Mouse
limbic system development GO:0021761 3 0.117
organ formation GO:0048645 3 0.117
hindbrain development GO:0030902 3 0.115
Zebrafish Mouse
pancreas development GO:0031016 19 0.114
gland development GO:0048732 48 0.114
Zebrafish Mouse
negative regulation of cell differentiation GO:0045596 171 0.114
Mouse
tube development GO:0035295 125 0.113
small molecule biosynthetic process GO:0044283 157 0.113
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.112
renal system development GO:0072001 63 0.111
organic hydroxy compound transport GO:0015850 63 0.111
enzyme linked receptor protein signaling pathway GO:0007167 303 0.110
positive regulation of phosphorylation GO:0042327 394 0.108
cellular response to endogenous stimulus GO:0071495 336 0.107
ion transmembrane transport GO:0034220 338 0.106
regulation of hormone secretion GO:0046883 57 0.104
specification of organ identity GO:0010092 3 0.103
renal system pattern specification GO:0072048 1 0.102
monocarboxylic acid biosynthetic process GO:0072330 67 0.101
central nervous system development GO:0007417 123 0.100
Zebrafish Mouse
negative regulation of cell death GO:0060548 345 0.100
Mouse
response to organic cyclic compound GO:0014070 204 0.099
fatty acid metabolic process GO:0006631 115 0.098
vasculature development GO:0001944 181 0.098
organic anion transport GO:0015711 103 0.097
neuron differentiation GO:0030182 138 0.097
cation transport GO:0006812 331 0.096
response to hormone GO:0009725 175 0.096
blood vessel development GO:0001568 172 0.095
segmentation GO:0035282 4 0.092
positive regulation of kinase activity GO:0033674 204 0.090
regulation of ion transport GO:0043269 189 0.089
amine metabolic process GO:0009308 44 0.088
forebrain neuron differentiation GO:0021879 3 0.088
negative regulation of phosphate metabolic process GO:0045936 267 0.088
positive regulation of protein phosphorylation GO:0001934 313 0.087
carbohydrate metabolic process GO:0005975 207 0.087
ion homeostasis GO:0050801 230 0.085
system process GO:0003008 349 0.085
Human
response to abiotic stimulus GO:0009628 336 0.084
actin filament based process GO:0030029 224 0.084
negative regulation of protein metabolic process GO:0051248 391 0.083
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.083
lipid biosynthetic process GO:0008610 177 0.082
regulation of cell cycle GO:0051726 393 0.082
peptide transport GO:0015833 74 0.081
Human Mouse
steroid metabolic process GO:0008202 94 0.079
regulation of cell motility GO:2000145 299 0.079
regulation of anatomical structure morphogenesis GO:0022603 286 0.078
Mouse
stem cell differentiation GO:0048863 93 0.078
Mouse
regulation of growth GO:0040008 165 0.078
Mouse
locomotory behavior GO:0007626 1 0.077
peptidyl tyrosine phosphorylation GO:0018108 170 0.076
neurological system process GO:0050877 163 0.076
nervous system development GO:0007399 293 0.076
Zebrafish Mouse
regulation of cell migration GO:0030334 289 0.075
regulation of kinase activity GO:0043549 314 0.075
morphogenesis of embryonic epithelium GO:0016331 4 0.075
Mouse
determination of adult lifespan GO:0008340 2 0.074
kidney morphogenesis GO:0060993 19 0.073
regulation of protein kinase activity GO:0045859 289 0.073
peptidyl tyrosine modification GO:0018212 170 0.072
head development GO:0060322 108 0.072
Zebrafish Mouse
regulation of peptide secretion GO:0002791 42 0.072
cell adhesion GO:0007155 325 0.071
oxidation reduction process GO:0055114 396 0.070
extraocular skeletal muscle development GO:0002074 1 0.069
immune system development GO:0002520 195 0.068
positive regulation of programmed cell death GO:0043068 249 0.068
regulation of homeostatic process GO:0032844 121 0.068
embryo development GO:0009790 123 0.067
Zebrafish Mouse
cation transmembrane transport GO:0098655 238 0.067
regulation of anatomical structure size GO:0090066 101 0.067
generation of neurons GO:0048699 152 0.066
negative regulation of phosphorus metabolic process GO:0010563 267 0.065
tissue homeostasis GO:0001894 63 0.065
biological adhesion GO:0022610 331 0.065
vesicle mediated transport GO:0016192 371 0.064
hematopoietic or lymphoid organ development GO:0048534 186 0.064
positive regulation of protein kinase activity GO:0045860 190 0.063
neurogenesis GO:0022008 169 0.063
cell development GO:0048468 328 0.062
Zebrafish Mouse
carboxylic acid transport GO:0046942 63 0.062
sulfur compound metabolic process GO:0006790 101 0.062
sodium dependent organic cation transport GO:0070715 1 0.062
cellular response to oxygen containing compound GO:1901701 276 0.061
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.060
nucleoside catabolic process GO:0009164 408 0.060
regulation of protein localization GO:0032880 296 0.059
negative regulation of catalytic activity GO:0043086 335 0.059
lipid transport GO:0006869 90 0.058
carnitine transmembrane transport GO:1902603 3 0.058
cell substrate adhesion GO:0031589 132 0.058
negative regulation of multicellular organismal process GO:0051241 317 0.058
Mouse
membrane organization GO:0061024 292 0.058
response to drug GO:0042493 81 0.058
peripheral nervous system development GO:0007422 2 0.057
purine containing compound catabolic process GO:0072523 411 0.057
purine nucleoside triphosphate metabolic process GO:0009144 412 0.056
regulation of insulin secretion GO:0050796 33 0.056
response to carbohydrate GO:0009743 21 0.055
Mouse
ras protein signal transduction GO:0007265 73 0.055
blastoderm segmentation GO:0007350 2 0.055
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
multicellular organismal aging GO:0010259 3 0.054
chordate embryonic development GO:0043009 34 0.054
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.054
chromatin modification GO:0016568 298 0.054
cell fate determination GO:0001709 3 0.054
regulation of peptide transport GO:0090087 62 0.053
divalent inorganic cation transport GO:0072511 158 0.053
purine nucleotide catabolic process GO:0006195 405 0.053
ribonucleotide catabolic process GO:0009261 405 0.052
glucose homeostasis GO:0042593 31 0.052
Human
skeletal system development GO:0001501 79 0.052
somatic stem cell maintenance GO:0035019 4 0.052
Mouse
negative regulation of cellular component organization GO:0051129 235 0.052
nicotinate transport GO:2001142 1 0.051
regulation of calcium ion transport GO:0051924 79 0.051
forebrain regionalization GO:0021871 3 0.051
negative regulation of cellular amine metabolic process GO:0033239 3 0.051
cytoplasmic transport GO:0016482 379 0.051
cell morphogenesis involved in differentiation GO:0000904 144 0.051
negative regulation of protein modification process GO:0031400 200 0.051
positive regulation of transport GO:0051050 336 0.051
heart development GO:0007507 95 0.051
regulation of locomotion GO:0040012 329 0.050
organic acid transport GO:0015849 65 0.050
single organism carbohydrate metabolic process GO:0044723 193 0.050
pattern specification process GO:0007389 43 0.050
Zebrafish Mouse
growth GO:0040007 202 0.049
Mouse
single organism cellular localization GO:1902580 332 0.049
cardiac right ventricle morphogenesis GO:0003215 3 0.049
regulation of mapk cascade GO:0043408 262 0.048
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.048
nucleoside phosphate catabolic process GO:1901292 412 0.047
actin cytoskeleton organization GO:0030036 207 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.046
positive regulation of cell death GO:0010942 263 0.046
purine ribonucleoside metabolic process GO:0046128 437 0.045
cell matrix adhesion GO:0007160 85 0.045
nucleoside triphosphate metabolic process GO:0009141 422 0.045
digestive system development GO:0055123 75 0.045
Zebrafish Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.045
positive regulation of cell development GO:0010720 92 0.045
organic hydroxy compound metabolic process GO:1901615 147 0.045
multicellular organismal homeostasis GO:0048871 67 0.045
regulation of cellular component movement GO:0051270 334 0.045
regulation of transferase activity GO:0051338 355 0.045
regulation of establishment of protein localization GO:0070201 242 0.044
regionalization GO:0003002 29 0.044
Zebrafish Mouse
organophosphate catabolic process GO:0046434 430 0.044
regulation of mitotic cell cycle GO:0007346 189 0.044
positive regulation of transferase activity GO:0051347 227 0.044
insulin secretion GO:0030073 39 0.044
Human Mouse
fatty acid biosynthetic process GO:0006633 46 0.044
regulation of neurogenesis GO:0050767 82 0.044
lipid localization GO:0010876 106 0.044
regulation of proteolysis GO:0030162 293 0.044
epithelium migration GO:0090132 119 0.043
neuron development GO:0048666 113 0.043
negative regulation of transport GO:0051051 176 0.043
mitotic cell cycle GO:0000278 326 0.042
regulation of lipid metabolic process GO:0019216 96 0.042
mapk cascade GO:0000165 288 0.042
regulation of protein transport GO:0051223 213 0.042
ribonucleoside catabolic process GO:0042454 406 0.041
positive regulation of cellular component biogenesis GO:0044089 158 0.041
cellular modified amino acid metabolic process GO:0006575 64 0.041
regulation of protein serine threonine kinase activity GO:0071900 179 0.041
regulation of intracellular transport GO:0032386 195 0.041
positive regulation of cellular catabolic process GO:0031331 284 0.041
nucleoside triphosphate catabolic process GO:0009143 394 0.040
digestive tract morphogenesis GO:0048546 56 0.040
Zebrafish Mouse
single organism membrane organization GO:0044802 268 0.040
neuromuscular junction development GO:0007528 3 0.040
negative regulation of programmed cell death GO:0043069 321 0.039
Mouse
negative regulation of phosphorylation GO:0042326 174 0.039
negative regulation of apoptotic process GO:0043066 316 0.039
Mouse
digestive tract development GO:0048565 75 0.039
Zebrafish Mouse
menstrual cycle phase GO:0022601 2 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
formation of primary germ layer GO:0001704 42 0.038
Zebrafish Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
cell projection assembly GO:0030031 126 0.038
regulation of cell growth GO:0001558 135 0.038
rho protein signal transduction GO:0007266 26 0.038
gastrulation GO:0007369 51 0.038
Zebrafish Mouse
cellular response to hormone stimulus GO:0032870 125 0.037
brain development GO:0007420 97 0.037
Zebrafish Mouse
regulation of stem cell differentiation GO:2000736 56 0.037
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.037
activation of protein kinase activity GO:0032147 90 0.037
embryonic camera type eye development GO:0031076 2 0.037
morphogenesis of an epithelium GO:0002009 60 0.037
Zebrafish Mouse
kidney epithelium development GO:0072073 25 0.037
regulation of cell cycle process GO:0010564 266 0.037
response to hexose GO:0009746 20 0.037
Mouse
hemopoiesis GO:0030097 180 0.037
angiogenesis GO:0001525 147 0.037
regulation of peptidase activity GO:0052547 180 0.036
inorganic cation transmembrane transport GO:0098662 194 0.036
cell projection morphogenesis GO:0048858 129 0.036
mesenchyme development GO:0060485 59 0.036
sodium independent organic anion transport GO:0043252 2 0.036
response to nitrogen compound GO:1901698 184 0.036
positive regulation of protein complex assembly GO:0031334 86 0.036
cellular response to abiotic stimulus GO:0071214 117 0.036
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.035
cardiac chamber morphogenesis GO:0003206 26 0.035
regulation of endopeptidase activity GO:0052548 170 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
myeloid cell differentiation GO:0030099 117 0.035
regulation of nervous system development GO:0051960 88 0.035
negative regulation of locomotion GO:0040013 118 0.035
positive regulation of cell motility GO:2000147 177 0.035
glycerolipid metabolic process GO:0046486 107 0.034
appendage morphogenesis GO:0035107 16 0.034
neuroendocrine cell differentiation GO:0061101 2 0.034
gtp catabolic process GO:0006184 237 0.034
interspecies interaction between organisms GO:0044419 156 0.034
anatomical structure homeostasis GO:0060249 100 0.034
negative regulation of cell motility GO:2000146 104 0.034
embryonic camera type eye formation GO:0060900 2 0.034
female gamete generation GO:0007292 2 0.034
regulation of wnt signaling pathway GO:0030111 123 0.034
Mouse
leukocyte migration GO:0050900 107 0.033
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.033
ribonucleoside triphosphate metabolic process GO:0009199 412 0.033
organic hydroxy compound biosynthetic process GO:1901617 71 0.033
neural tube patterning GO:0021532 2 0.033
lipid modification GO:0030258 84 0.033
anterior posterior axis specification GO:0009948 2 0.033
protein processing GO:0016485 226 0.033
negative regulation of intracellular signal transduction GO:1902532 183 0.033
epithelial cell fate commitment GO:0072148 3 0.033
renal system process GO:0003014 25 0.033
Human
negative regulation of cell migration GO:0030336 102 0.033
behavior GO:0007610 112 0.033
cell part morphogenesis GO:0032990 137 0.033
regeneration GO:0031099 4 0.032
cellular chemical homeostasis GO:0055082 180 0.032
cardiocyte differentiation GO:0035051 23 0.032
immune response GO:0006955 307 0.032
cellular metal ion homeostasis GO:0006875 146 0.032
positive regulation of intestinal epithelial structure maintenance GO:0060731 1 0.032
nucleotide catabolic process GO:0009166 408 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.032
negative regulation of cellular component movement GO:0051271 106 0.032
negative regulation of stem cell differentiation GO:2000737 22 0.031
Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.031
metencephalon development GO:0022037 2 0.031
inorganic ion transmembrane transport GO:0098660 231 0.031
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
cellular macromolecule catabolic process GO:0044265 380 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
gtp metabolic process GO:0046039 239 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
renal tubular secretion GO:0097254 1 0.031
regulation of epithelial cell migration GO:0010632 93 0.030
protein localization to organelle GO:0033365 280 0.030
positive regulation of nucleotide metabolic process GO:0045981 230 0.030
positive regulation of cardioblast differentiation GO:0051891 2 0.030
nucleoside phosphate biosynthetic process GO:1901293 109 0.030
regulation of protein maturation GO:1903317 150 0.030
regulation of body fluid levels GO:0050878 99 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
alcohol metabolic process GO:0006066 114 0.030
pronephros development GO:0048793 2 0.030
epithelial tube morphogenesis GO:0060562 38 0.030
Mouse
positive regulation of proteolysis GO:0045862 142 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
cellular cation homeostasis GO:0030003 163 0.030
cellular ion homeostasis GO:0006873 168 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.029
response to growth factor GO:0070848 205 0.029
memory GO:0007613 3 0.029
regulation of cellular response to stress GO:0080135 244 0.029
cellular response to growth factor stimulus GO:0071363 197 0.029
response to inorganic substance GO:0010035 127 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.029
embryonic forelimb morphogenesis GO:0035115 4 0.029
metal ion transport GO:0030001 272 0.029
nephron epithelium development GO:0072009 23 0.029
protein localization to membrane GO:0072657 160 0.029
intracellular protein transport GO:0006886 270 0.028
multi organism cellular process GO:0044764 156 0.028
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 2 0.028
regulation of neuron differentiation GO:0045664 70 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.028
epithelial cell migration GO:0010631 119 0.028
wnt signaling pathway GO:0016055 156 0.028
Mouse
hemostasis GO:0007599 76 0.028
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.028
Mouse
response to biotic stimulus GO:0009607 276 0.028
regulation of heart growth GO:0060420 4 0.028
developmental programmed cell death GO:0010623 3 0.028
Mouse
monosaccharide metabolic process GO:0005996 74 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
blastocyst development GO:0001824 3 0.028
Mouse
sterol transport GO:0015918 39 0.028
positive regulation of catabolic process GO:0009896 310 0.028
cellular response to organonitrogen compound GO:0071417 124 0.028
regulation of cell morphogenesis GO:0022604 153 0.027
negative regulation of protein phosphorylation GO:0001933 140 0.027
guanosine containing compound catabolic process GO:1901069 239 0.027
soft palate development GO:0060023 3 0.027
cell type specific apoptotic process GO:0097285 125 0.027
Mouse
epidermal cell differentiation GO:0009913 45 0.027
glycosyl compound catabolic process GO:1901658 413 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
steroid biosynthetic process GO:0006694 46 0.026
cellular calcium ion homeostasis GO:0006874 117 0.026
stem cell development GO:0048864 69 0.026
Mouse
regulation of cell adhesion GO:0030155 166 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
regulation of protein complex assembly GO:0043254 147 0.026
negative regulation of cell cycle GO:0045786 193 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
regulation of cell matrix adhesion GO:0001952 42 0.026
cartilage condensation GO:0001502 1 0.026
regulation of gtp catabolic process GO:0033124 180 0.026
response to monosaccharide GO:0034284 20 0.025
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.025
divalent inorganic cation homeostasis GO:0072507 136 0.025
oogenesis GO:0048477 2 0.025
anion transmembrane transport GO:0098656 76 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
cellular response to hypoxia GO:0071456 51 0.025
mesenchymal cell differentiation GO:0048762 52 0.025
reproductive process GO:0022414 106 0.025
quorum sensing involved in interaction with host GO:0052106 1 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
epidermis development GO:0008544 59 0.025
response to lipid GO:0033993 206 0.025
cellular amide metabolic process GO:0043603 69 0.024
embryonic epithelial tube formation GO:0001838 4 0.024
Mouse
negative regulation of endopeptidase activity GO:0010951 84 0.024
carbohydrate homeostasis GO:0033500 31 0.024
Human
lipid catabolic process GO:0016042 84 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.024
response to disaccharide GO:0034285 1 0.024
regulation of cell projection organization GO:0031344 107 0.024
response to salt stress GO:0009651 3 0.024
protein targeting to nucleus GO:0044744 104 0.024
protein catabolic process GO:0030163 325 0.024
protein oligomerization GO:0051259 173 0.024
tissue migration GO:0090130 119 0.024
adult locomotory behavior GO:0008344 1 0.024
negative regulation of protein processing GO:0010955 142 0.024
regulation of cell substrate adhesion GO:0010810 68 0.024
chromatin organization GO:0006325 351 0.024
gabaergic neuron differentiation GO:0097154 1 0.023
metal ion homeostasis GO:0055065 169 0.023
bile acid metabolic process GO:0008206 14 0.023
response to acid chemical GO:0001101 66 0.023
apoptotic signaling pathway GO:0097190 268 0.023
response to mercury ion GO:0046689 4 0.023
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.023
heart morphogenesis GO:0003007 48 0.023
protein targeting GO:0006605 187 0.023
protein localization to nucleus GO:0034504 136 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
positive regulation of immune system process GO:0002684 283 0.023
ectodermal placode formation GO:0060788 1 0.023
Zebrafish
response to other organism GO:0051707 261 0.023
forebrain development GO:0030900 26 0.023
regulation of gtpase activity GO:0043087 180 0.023
cofactor metabolic process GO:0051186 87 0.023
ventral spinal cord development GO:0021517 1 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
positive regulation of homeostatic process GO:0032846 47 0.023
hippocampus development GO:0021766 1 0.023
regulation of myeloid cell differentiation GO:0045637 81 0.023
positive regulation of gtpase activity GO:0043547 166 0.023
response to external biotic stimulus GO:0043207 261 0.023
positive regulation of synaptic transmission GO:0050806 4 0.023
azole transport GO:0045117 4 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
salivary gland morphogenesis GO:0007435 4 0.022
urogenital system development GO:0001655 65 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
leukocyte differentiation GO:0002521 98 0.022
positive regulation of cell cycle GO:0045787 140 0.022
regulation of blood volume by renin angiotensin GO:0002016 1 0.022
nucleocytoplasmic transport GO:0006913 176 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.022
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
wound healing GO:0042060 115 0.022
hexose metabolic process GO:0019318 55 0.022
microtubule based process GO:0007017 210 0.022
ameboidal type cell migration GO:0001667 135 0.022
single organismal cell cell adhesion GO:0016337 148 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
nephron tubule development GO:0072080 17 0.022
embryonic organ morphogenesis GO:0048562 24 0.021
Zebrafish Mouse
regulation of epithelial cell proliferation GO:0050678 113 0.021
defense response GO:0006952 315 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
protein ubiquitination GO:0016567 314 0.021
cellular carbohydrate metabolic process GO:0044262 84 0.021
muscle structure development GO:0061061 98 0.021
cellular component disassembly GO:0022411 92 0.021

HNF1B disease predictions

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 11 0.226
kidney disease DOID:557 36 0.226
urinary system disease DOID:18 40 0.226
disease of metabolism DOID:0014667 295 0.148
acquired metabolic disease DOID:0060158 58 0.148
cancer DOID:162 167 0.065
disease of cellular proliferation DOID:14566 174 0.065
diabetes mellitus DOID:9351 31 0.045
type 2 diabetes mellitus DOID:9352 28 0.045
carbohydrate metabolism disease DOID:0050013 32 0.045
glucose metabolism disease DOID:4194 32 0.045
organ system cancer DOID:0050686 164 0.043
sensory system disease DOID:0050155 203 0.029
nervous system disease DOID:863 431 0.029