IMP

Process View

Homo sapiens

1 genes annotated in human

positive regulation of intestinal epithelial structure maintenance

Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of intestinal epithelial structure maintenance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of intestinal epithelial structure maintenance" (in gray)

Name	Description	Probability	Func Analog Organism
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.791
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.783
NCR2	natural cytotoxicity triggering receptor 2	0.752
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.678
PRODH2	proline dehydrogenase (oxidase) 2	0.495
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.348	Human
SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	0.207
AGXT	alanine-glyoxylate aminotransferase	0.196
SLC22A8	solute carrier family 22 (organic anion transporter), member 8	0.185	Human
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.149
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	0.130
DRD2	dopamine receptor D2	0.128
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.117	Human
SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.100
FTCD	formiminotransferase cyclodeaminase	0.097
GCGR	glucagon receptor	0.093
SLC13A3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.092
GLYAT	glycine-N-acyltransferase	0.074
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.068
AQP7	aquaporin 7	0.062
SLC17A3	solute carrier family 17 (sodium phosphate), member 3	0.059
TREH	trehalase (brush-border membrane glycoprotein)	0.057
CCL1	chemokine (C-C motif) ligand 1	0.054
NAT8B	N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)	0.053
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.052
HNF4A	hepatocyte nuclear factor 4, alpha	0.051
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.049	Human
DAO	D-amino-acid oxidase	0.047
RDH16	retinol dehydrogenase 16 (all-trans)	0.046
AIRE	autoimmune regulator	0.046
GDF2	growth differentiation factor 2	0.046
FXYD2	FXYD domain containing ion transport regulator 2	0.045
GPR31	G protein-coupled receptor 31	0.044
DPYS	dihydropyrimidinase	0.043
CLCNKB	chloride channel Kb	0.043
CHRND	cholinergic receptor, nicotinic, delta	0.042
CRYBB3	crystallin, beta B3	0.041
UPB1	ureidopropionase, beta	0.040
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.039
MASP2	mannan-binding lectin serine peptidase 2	0.037
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.036
HRG	histidine-rich glycoprotein	0.036
ALDOB	aldolase B, fructose-bisphosphate	0.035
RTP3	receptor (chemosensory) transporter protein 3	0.034
CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	0.034
C21orf62	chromosome 21 open reading frame 62	0.034
HPX	hemopexin	0.033
TM4SF5	transmembrane 4 L six family member 5	0.033
ALPI	alkaline phosphatase, intestinal	0.033
HNF1B	HNF1 homeobox B	0.032
HPD	4-hydroxyphenylpyruvate dioxygenase	0.031
PKLR	pyruvate kinase, liver and RBC	0.031
KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	0.029
UMOD	uromodulin	0.028
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.028
CPN2	carboxypeptidase N, polypeptide 2	0.027
CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1	0.027
HAO2	hydroxyacid oxidase 2 (long chain)	0.027
C8A	complement component 8, alpha polypeptide	0.026
EID3	EP300 interacting inhibitor of differentiation 3	0.026
SSTR3	somatostatin receptor 3	0.026
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	0.026
IGFALS	insulin-like growth factor binding protein, acid labile subunit	0.026
LASS2	LAG1 homolog, ceramide synthase 2	0.025
AQP2	aquaporin 2 (collecting duct)	0.025
OR2F1	olfactory receptor, family 2, subfamily F, member 1	0.025
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.025
HOXC8	homeobox C8	0.024
VIL1	villin 1	0.023
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.022
UPP2	uridine phosphorylase 2	0.022
OTOF	otoferlin	0.021
PROZ	protein Z, vitamin K-dependent plasma glycoprotein	0.021
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.021
WNT10B	wingless-type MMTV integration site family, member 10B	0.021
HABP2	hyaluronan binding protein 2	0.020
NPFFR1	neuropeptide FF receptor 1	0.020
ESRRB	estrogen-related receptor beta	0.020
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.020
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.020
IL27	interleukin 27	0.019
GIP	gastric inhibitory polypeptide	0.019
AQP6	aquaporin 6, kidney specific	0.019
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.019
G6PC	glucose-6-phosphatase, catalytic subunit	0.019
CA5A	carbonic anhydrase VA, mitochondrial	0.019
SLC22A2	solute carrier family 22 (organic cation transporter), member 2	0.018	Human
RDH12	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)	0.018
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.018
C9	complement component 9	0.018
SLC26A1	solute carrier family 26 (sulfate transporter), member 1	0.017
TTBK1	tau tubulin kinase 1	0.017
RTDR1	rhabdoid tumor deletion region gene 1	0.017
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.017
BPI	bactericidal/permeability-increasing protein	0.017
SPATA21	spermatogenesis associated 21	0.017
ALPPL2	alkaline phosphatase, placental-like 2	0.017
TNNI1	troponin I type 1 (skeletal, slow)	0.017
PRLH	prolactin releasing hormone	0.017
KRT37	keratin 37	0.017
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.017
GFRA4	GDNF family receptor alpha 4	0.017
A1CF	APOBEC1 complementation factor	0.017
LPA	lipoprotein, Lp(a)	0.017
IL1RL2	interleukin 1 receptor-like 2	0.016
MIOX	myo-inositol oxygenase	0.016
OR10S1	olfactory receptor, family 10, subfamily S, member 1	0.016
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.016
GGTLC1	gamma-glutamyltransferase light chain 1	0.016
IFNA6	interferon, alpha 6	0.016
UNC93A	unc-93 homolog A (C. elegans)	0.016
CXCR1	chemokine (C-X-C motif) receptor 1	0.016
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.016
AGXT2	alanine--glyoxylate aminotransferase 2	0.016
CDHR5	cadherin-related family member 5	0.016
AMN	amnionless homolog (mouse)	0.016
CDH16	cadherin 16, KSP-cadherin	0.016
SAA4	serum amyloid A4, constitutive	0.016
KLK15	kallikrein-related peptidase 15	0.016
CCIN	calicin	0.016
TEX13A	testis expressed 13A	0.016
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.015
PDZK1	PDZ domain containing 1	0.015
CRYAA	crystallin, alpha A	0.015
IL1F10	interleukin 1 family, member 10 (theta)	0.015
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.015
CRP	C-reactive protein, pentraxin-related	0.015
NYX	nyctalopin	0.015
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.015
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.015
EXOC3L1	exocyst complex component 3-like 1	0.015
CELA1	chymotrypsin-like elastase family, member 1	0.015
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.015
GRPR	gastrin-releasing peptide receptor	0.014
PGLYRP4	peptidoglycan recognition protein 4	0.014
SYT11	synaptotagmin XI	0.014
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.014
SCT	secretin	0.014
DUSP13	dual specificity phosphatase 13	0.014
KISS1	KiSS-1 metastasis-suppressor	0.014
SLC1A7	solute carrier family 1 (glutamate transporter), member 7	0.014
SLC17A2	solute carrier family 17 (sodium phosphate), member 2	0.014
FUT5	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	0.014
NPHS1	nephrosis 1, congenital, Finnish type (nephrin)	0.014
TMEM174	transmembrane protein 174	0.014
LHB	luteinizing hormone beta polypeptide	0.014
GGTLC2	gamma-glutamyltransferase light chain 2	0.014
PRM2	protamine 2	0.013
FSHB	follicle stimulating hormone, beta polypeptide	0.013
HCRTR1	hypocretin (orexin) receptor 1	0.013
CHRNA10	cholinergic receptor, nicotinic, alpha 10	0.013
CNGB3	cyclic nucleotide gated channel beta 3	0.013
APH1B	anterior pharynx defective 1 homolog B (C. elegans)	0.013
ASGR2	asialoglycoprotein receptor 2	0.013
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.013
PLG	plasminogen	0.013
PAX8	paired box 8	0.013
TBX10	T-box 10	0.013
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.013
SLC39A5	solute carrier family 39 (metal ion transporter), member 5	0.013
PTH1R	parathyroid hormone 1 receptor	0.013
ARR3	arrestin 3, retinal (X-arrestin)	0.013
HIST1H1T	histone cluster 1, H1t	0.013
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.013
SLC7A9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.013
UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	0.013
HYAL3	hyaluronoglucosaminidase 3	0.013
KRTAP5-8	keratin associated protein 5-8	0.013
SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.012
TAL2	T-cell acute lymphocytic leukemia 2	0.012
GPHB5	glycoprotein hormone beta 5	0.012
BTNL3	butyrophilin-like 3	0.012
KRT84	keratin 84	0.012
FOLR3	folate receptor 3 (gamma)	0.012
BHMT	betaine--homocysteine S-methyltransferase	0.012
HIPK4	homeodomain interacting protein kinase 4	0.012
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.012
AMELY	amelogenin, Y-linked	0.012
SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.012
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	0.012
MYL10	myosin, light chain 10, regulatory	0.012
GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.012
KRTAP17-1	keratin associated protein 17-1	0.012
CST2	cystatin SA	0.012
ANKRD53	ankyrin repeat domain 53	0.012
C8B	complement component 8, beta polypeptide	0.012
CCL24	chemokine (C-C motif) ligand 24	0.012
ZAN	zonadhesin	0.011
C9orf71	chromosome 9 open reading frame 71	0.011
P2RY4	pyrimidinergic receptor P2Y, G-protein coupled, 4	0.011
APOB	apolipoprotein B (including Ag(x) antigen)	0.011
CASR	calcium-sensing receptor	0.011
KNG1	kininogen 1	0.011
TRPM8	transient receptor potential cation channel, subfamily M, member 8	0.011
CRYGC	crystallin, gamma C	0.011
HOXD10	homeobox D10	0.011
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.011
FOXN1	forkhead box N1	0.011
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.011
KRT82	keratin 82	0.011
ADCY8	adenylate cyclase 8 (brain)	0.011
CLCN1	chloride channel 1, skeletal muscle	0.011
CREB3L3	cAMP responsive element binding protein 3-like 3	0.011
TGM5	transglutaminase 5	0.011
AANAT	aralkylamine N-acetyltransferase	0.011
OR6T1	olfactory receptor, family 6, subfamily T, member 1	0.011
ACSM2A	acyl-CoA synthetase medium-chain family member 2A	0.011
DMP1	dentin matrix acidic phosphoprotein 1	0.011
NEU2	sialidase 2 (cytosolic sialidase)	0.011
ESPNL	espin-like	0.011
FITM1	fat storage-inducing transmembrane protein 1	0.011
AVPR2	arginine vasopressin receptor 2	0.011
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.011
ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	0.011
LRTM1	leucine-rich repeats and transmembrane domains 1	0.011
KLK3	kallikrein-related peptidase 3	0.011
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.011
LELP1	late cornified envelope-like proline-rich 1	0.011
ACPT	acid phosphatase, testicular	0.011
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.011
LIPC	lipase, hepatic	0.010
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.010
NPC1L1	NPC1 (Niemann-Pick disease, type C1, gene)-like 1	0.010
PBOV1	prostate and breast cancer overexpressed 1	0.010
F11	coagulation factor XI	0.010
AGXT2L1	alanine-glyoxylate aminotransferase 2-like 1	0.010
SLC25A47	solute carrier family 25, member 47	0.010
TRPC7	transient receptor potential cation channel, subfamily C, member 7	0.010
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.010
UROC1	urocanase domain containing 1	0.010
PNMA3	paraneoplastic antigen MA3	0.010
SLC25A20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	0.010
CST5	cystatin D	0.010
ADM2	adrenomedullin 2	0.010
SLC5A12	solute carrier family 5 (sodium/glucose cotransporter), member 12	0.010
SPP2	secreted phosphoprotein 2, 24kDa	0.010
SLC38A3	solute carrier family 38, member 3	0.010
FOXI1	forkhead box I1	0.010
IBSP	integrin-binding sialoprotein	0.010
PLA2G12B	phospholipase A2, group XIIB	0.010
GCM1	glial cells missing homolog 1 (Drosophila)	0.010