Homo sapiens

221 known processes

HSPA1B

heat shock 70kDa protein 1B

(Aliases: HSP70-1B,HSPA1A,FLJ54328,HSP70-2)

HSPA1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein refolding GO:0042026 14 1.000
intracellular protein transmembrane transport GO:0065002 24 0.999
Yeast
establishment of protein localization to mitochondrion GO:0072655 22 0.998
Yeast
chaperone cofactor dependent protein refolding GO:0070389 4 0.996
positive regulation of meiotic cell cycle GO:0051446 2 0.995
Worm
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.994
ribonucleoprotein complex disassembly GO:0032988 7 0.994
Yeast
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.986
response to unfolded protein GO:0006986 24 0.984
cotranslational protein targeting to membrane GO:0006613 2 0.982
Yeast
cellular heat acclimation GO:0070370 3 0.981
protein folding GO:0006457 38 0.979
regulation of erythrocyte differentiation GO:0045646 17 0.978
regulation of inclusion body assembly GO:0090083 13 0.969
negative regulation of apoptotic process GO:0043066 316 0.969
srp dependent cotranslational protein targeting to membrane GO:0006614 2 0.967
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 158 0.961
negative regulation of inclusion body assembly GO:0090084 9 0.960
positive regulation of erythrocyte differentiation GO:0045648 11 0.953
ribonucleoside monophosphate metabolic process GO:0009161 187 0.952
nucleoside catabolic process GO:0009164 408 0.951
response to topologically incorrect protein GO:0035966 29 0.949
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.948
purine nucleoside triphosphate metabolic process GO:0009144 412 0.944
regulation of meiotic cell cycle GO:0051445 4 0.943
Worm
nucleoside triphosphate metabolic process GO:0009141 422 0.939
ribonucleoside catabolic process GO:0042454 406 0.936
nucleoside monophosphate metabolic process GO:0009123 191 0.936
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.931
cellular response to topologically incorrect protein GO:0035967 19 0.928
Fly
purine nucleoside catabolic process GO:0006152 398 0.927
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.923
ribonucleoside triphosphate metabolic process GO:0009199 412 0.919
purine ribonucleotide catabolic process GO:0009154 404 0.918
glycosyl compound catabolic process GO:1901658 413 0.918
purine nucleoside monophosphate metabolic process GO:0009126 186 0.916
nucleoside monophosphate catabolic process GO:0009125 159 0.911
retrograde transport endosome to golgi GO:0042147 45 0.910
Worm
atp metabolic process GO:0046034 176 0.910
ribonucleoside triphosphate catabolic process GO:0009203 391 0.903
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.899
inclusion body assembly GO:0070841 17 0.899
protein localization to endoplasmic reticulum GO:0070972 19 0.894
Yeast
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.877
regulation of fibril organization GO:1902903 1 0.875
Human
de novo protein folding GO:0006458 2 0.874
atp catabolic process GO:0006200 157 0.873
purine containing compound catabolic process GO:0072523 411 0.863
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.858
heat acclimation GO:0010286 3 0.841
erythrocyte differentiation GO:0030218 28 0.839
negative regulation of protein modification process GO:0031400 200 0.818
organophosphate catabolic process GO:0046434 430 0.817
purine nucleoside triphosphate catabolic process GO:0009146 392 0.816
nucleotide catabolic process GO:0009166 408 0.806
purine nucleoside monophosphate catabolic process GO:0009128 158 0.804
protein localization to mitochondrion GO:0070585 25 0.789
Yeast
regulation of cell cycle GO:0051726 393 0.781
Worm
de novo posttranslational protein folding GO:0051084 2 0.781
chaperone mediated protein folding GO:0061077 13 0.779
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.757
Yeast
cellular response to misfolded protein GO:0071218 2 0.751
mitochondrial transport GO:0006839 60 0.750
Yeast
negative regulation of apoptotic signaling pathway GO:2001234 97 0.742
nucleoside phosphate catabolic process GO:1901292 412 0.740
nucleoside triphosphate catabolic process GO:0009143 394 0.734
negative regulation of cellular protein metabolic process GO:0032269 353 0.727
negative regulation of cell death GO:0060548 345 0.727
cellular macromolecule catabolic process GO:0044265 380 0.723
response to abiotic stimulus GO:0009628 336 0.721
negative regulation of mitotic cell cycle GO:0045930 102 0.712
Worm
protein ubiquitination GO:0016567 314 0.697
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.687
protein localization to membrane GO:0072657 160 0.675
Yeast
purine nucleotide catabolic process GO:0006195 405 0.671
ubiquitin dependent protein catabolic process GO:0006511 206 0.659
mrna catabolic process GO:0006402 56 0.657
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.656
positive regulation of catabolic process GO:0009896 310 0.652
apoptotic signaling pathway GO:0097190 268 0.651
negative regulation of cellular component organization GO:0051129 235 0.650
membrane organization GO:0061024 292 0.649
Yeast
generation of neurons GO:0048699 152 0.642
Fly
lipid metabolic process GO:0006629 381 0.634
regulation of myeloid cell differentiation GO:0045637 81 0.627
cellular response to heat GO:0034605 14 0.626
purine ribonucleoside catabolic process GO:0046130 398 0.621
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.604
hemopoiesis GO:0030097 180 0.599
establishment of protein localization to organelle GO:0072594 172 0.597
Yeast
protein catabolic process GO:0030163 325 0.596
Yeast
protein targeting to membrane GO:0006612 42 0.595
Yeast
negative regulation of protein metabolic process GO:0051248 391 0.595
positive regulation of developmental process GO:0051094 314 0.587
organelle disassembly GO:1903008 9 0.584
Yeast
vesicle mediated transport GO:0016192 371 0.581
Yeast Worm Fly
response to cytokine GO:0034097 232 0.578
ribonucleotide catabolic process GO:0009261 405 0.569
fibril organization GO:0097435 10 0.568
Human
secretion GO:0046903 254 0.560
Fly
signal transduction in absence of ligand GO:0038034 22 0.556
single organism membrane organization GO:0044802 268 0.538
Yeast
proteasomal protein catabolic process GO:0010498 176 0.537
regulation of apoptotic signaling pathway GO:2001233 175 0.532
regulation of nucleotide catabolic process GO:0030811 205 0.529
cell projection morphogenesis GO:0048858 129 0.527
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.521
protein localization to organelle GO:0033365 280 0.518
Yeast
regulation of homeostatic process GO:0032844 121 0.510
intracellular protein transport GO:0006886 270 0.501
Yeast
signal release GO:0023061 70 0.496
Fly
regulation of mitotic cell cycle GO:0007346 189 0.491
Worm
protein import into nucleus GO:0006606 104 0.482
Yeast
rna interference GO:0016246 4 0.478
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.465
positive regulation of cell differentiation GO:0045597 211 0.452
taxis GO:0042330 157 0.450
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.435
Fly
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.432
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.429
negative regulation of cell cycle GO:0045786 193 0.415
Worm
nucleocytoplasmic transport GO:0006913 176 0.414
Yeast
single organism nuclear import GO:1902593 104 0.411
Yeast
cell projection organization GO:0030030 252 0.408
Fly
positive regulation of cell cycle GO:0045787 140 0.404
Worm
response to temperature stimulus GO:0009266 22 0.403
regulation of peptidase activity GO:0052547 180 0.401
secretion by cell GO:0032940 226 0.392
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.387
regulation of protein kinase activity GO:0045859 289 0.386
cell type specific apoptotic process GO:0097285 125 0.385
negative regulation of programmed cell death GO:0043069 321 0.377
positive regulation of nucleotide catabolic process GO:0030813 185 0.373
establishment of protein localization to endoplasmic reticulum GO:0072599 11 0.371
Yeast
negative regulation of cell growth GO:0030308 83 0.367
negative regulation of protein ubiquitination GO:0031397 35 0.367
positive regulation of myeloid cell differentiation GO:0045639 39 0.365
response to organonitrogen compound GO:0010243 156 0.363
positive regulation of cellular amine metabolic process GO:0033240 7 0.362
protein modification by small protein conjugation GO:0032446 342 0.358
cellular protein catabolic process GO:0044257 261 0.356
Yeast
neuron projection development GO:0031175 106 0.352
Fly
modification dependent protein catabolic process GO:0019941 209 0.348
protein import GO:0017038 130 0.347
Yeast
nuclear transport GO:0051169 179 0.346
Yeast
positive regulation of hydrolase activity GO:0051345 331 0.346
protein depolymerization GO:0051261 30 0.344
Yeast
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.343
establishment of protein localization to membrane GO:0090150 121 0.325
Yeast
nervous system development GO:0007399 293 0.317
Fly
regulation of microtubule based process GO:0032886 74 0.317
regulation of cellular ketone metabolic process GO:0010565 50 0.315
cellular protein complex disassembly GO:0043624 36 0.314
Yeast
protein targeting GO:0006605 187 0.307
Yeast
nuclear import GO:0051170 106 0.302
Yeast
modification dependent macromolecule catabolic process GO:0043632 212 0.299
homeostasis of number of cells GO:0048872 40 0.296
regulation of purine nucleotide metabolic process GO:1900542 264 0.295
positive regulation of homeostatic process GO:0032846 47 0.294
neuron differentiation GO:0030182 138 0.292
Fly
mitotic cell cycle GO:0000278 326 0.292
Worm
mrna metabolic process GO:0016071 175 0.291
posttranscriptional gene silencing by rna GO:0035194 25 0.287
Fly
response to heat GO:0009408 21 0.278
regulation of atp metabolic process GO:1903578 29 0.276
positive regulation of immune system process GO:0002684 283 0.271
protein maturation GO:0051604 233 0.267
cell morphogenesis GO:0000902 296 0.262
Fly
cellular response to cytokine stimulus GO:0071345 181 0.261
neurotransmitter secretion GO:0007269 4 0.260
Fly
neuron development GO:0048666 113 0.250
Fly
determination of adult lifespan GO:0008340 2 0.246
Worm
mitochondrion organization GO:0007005 156 0.237
Yeast
growth GO:0040007 202 0.236
posttranscriptional gene silencing GO:0016441 25 0.234
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.230
Fly
negative regulation of protein phosphorylation GO:0001933 140 0.230
translational initiation GO:0006413 48 0.229
negative regulation of protein maturation GO:1903318 142 0.228
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.220
endocytosis GO:0006897 159 0.216
Worm
regulation of proteolysis GO:0030162 293 0.216
cellular macromolecular complex assembly GO:0034622 324 0.213
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.210
Fly
single organism cellular localization GO:1902580 332 0.208
Yeast
ras protein signal transduction GO:0007265 73 0.204
regulation of protein serine threonine kinase activity GO:0071900 179 0.200
regulation of cell differentiation GO:0045595 393 0.200
axonogenesis GO:0007409 31 0.200
Fly
receptor mediated endocytosis GO:0006898 84 0.191
Worm
protein localization to nucleus GO:0034504 136 0.191
Yeast
gtp catabolic process GO:0006184 237 0.187
positive regulation of programmed cell death GO:0043068 249 0.183
regulation of endopeptidase activity GO:0052548 170 0.181
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.177
cytoplasmic translation GO:0002181 8 0.176
Yeast
protein import into nucleus translocation GO:0000060 22 0.176
Yeast
cell growth GO:0016049 160 0.173
regulation of cellular component biogenesis GO:0044087 281 0.171
regulation of cellular amine metabolic process GO:0033238 11 0.169
positive regulation of nucleotide metabolic process GO:0045981 230 0.167
macromolecular complex disassembly GO:0032984 60 0.166
Yeast
regulation of purine nucleotide catabolic process GO:0033121 205 0.164
translation GO:0006412 132 0.162
Yeast
protein targeting to er GO:0045047 7 0.160
Yeast
spinal cord development GO:0021510 4 0.157
regulation of nucleoside metabolic process GO:0009118 209 0.141
covalent chromatin modification GO:0016569 254 0.141
establishment of vesicle localization GO:0051650 23 0.141
cell part morphogenesis GO:0032990 137 0.140
Fly
negative regulation of cell proliferation GO:0008285 228 0.135
cell development GO:0048468 328 0.134
Fly
regulation of lipid metabolic process GO:0019216 96 0.134
negative regulation of phosphorylation GO:0042326 174 0.132
post embryonic development GO:0009791 2 0.128
Worm
response to metal ion GO:0010038 84 0.127
axon development GO:0061564 34 0.124
Fly
regulation of protein ubiquitination GO:0031396 95 0.120
protein transmembrane transport GO:0071806 25 0.117
Yeast
regulation of atpase activity GO:0043462 25 0.114
small gtpase mediated signal transduction GO:0007264 78 0.113
response to drug GO:0042493 81 0.110
cellular component disassembly GO:0022411 92 0.109
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.108
striated muscle cell apoptotic process GO:0010658 3 0.106
embryonic epithelial tube formation GO:0001838 4 0.104
circulatory system development GO:0072359 262 0.103
cellular amino acid metabolic process GO:0006520 116 0.102
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.102
cellular component morphogenesis GO:0032989 314 0.101
Fly
immune system development GO:0002520 195 0.101
peptidyl serine modification GO:0018209 106 0.100
protein oligomerization GO:0051259 173 0.099
regulation of gene expression epigenetic GO:0040029 73 0.099
Fly
brain development GO:0007420 97 0.097
axon cargo transport GO:0008088 2 0.094
cellular response to mechanical stimulus GO:0071260 39 0.093
regulation of transferase activity GO:0051338 355 0.092
negative regulation of neuron apoptotic process GO:0043524 23 0.091
negative regulation of peptidase activity GO:0010466 91 0.091
guanosine containing compound metabolic process GO:1901068 244 0.091
cellular response to inorganic substance GO:0071241 45 0.090
aging GO:0007568 66 0.090
Worm
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.089
amine metabolic process GO:0009308 44 0.088
regulation of protein stability GO:0031647 87 0.088
negative regulation of phosphate metabolic process GO:0045936 267 0.087
gene silencing by rna GO:0031047 26 0.087
Fly
anterior posterior axis specification embryo GO:0008595 2 0.085
positive regulation of glucocorticoid receptor signaling pathway GO:2000324 1 0.085
cellular response to metal ion GO:0071248 43 0.085
oocyte differentiation GO:0009994 2 0.084
segmentation GO:0035282 4 0.083
regulation of cell growth GO:0001558 135 0.083
positive regulation of nucleoside metabolic process GO:0045979 186 0.082
protein stabilization GO:0050821 64 0.077
regulation of synaptic plasticity GO:0048167 3 0.077
cell activation GO:0001775 213 0.075
neurogenesis GO:0022008 169 0.073
Fly
cellular response to abiotic stimulus GO:0071214 117 0.073
cellular response to oxygen containing compound GO:1901701 276 0.073
central nervous system development GO:0007417 123 0.072
transmembrane transport GO:0055085 399 0.071
Yeast
morphogenesis of embryonic epithelium GO:0016331 4 0.070
cellular metal ion homeostasis GO:0006875 146 0.070
cellular response to tumor necrosis factor GO:0071356 63 0.069
microtubule based process GO:0007017 210 0.068
regulation of ion transport GO:0043269 189 0.067
regulation of cellular amino acid metabolic process GO:0006521 6 0.066
negative regulation of catalytic activity GO:0043086 335 0.066
regulation of cytokine production GO:0001817 232 0.065
negative regulation of amine transport GO:0051953 1 0.065
response to calcium ion GO:0051592 46 0.063
regulation of cell cycle process GO:0010564 266 0.062
regulation of nucleotide metabolic process GO:0006140 269 0.062
embryo development ending in birth or egg hatching GO:0009792 34 0.062
Worm Fly
regulation of neuron apoptotic process GO:0043523 35 0.061
positive regulation of cytokine production GO:0001819 167 0.061
negative regulation of neuron death GO:1901215 32 0.061
cellular amine metabolic process GO:0044106 41 0.060
cellular homeostasis GO:0019725 196 0.060
sleep GO:0030431 2 0.059
behavior GO:0007610 112 0.059
positive regulation of transferase activity GO:0051347 227 0.058
regulation of secretion GO:0051046 194 0.057
cell cell signaling GO:0007267 155 0.057
Fly
monocarboxylic acid metabolic process GO:0032787 185 0.056
axon guidance GO:0007411 12 0.056
Fly
regulation of cellular response to stress GO:0080135 244 0.056
positive regulation of endothelial cell migration GO:0010595 39 0.055
tube development GO:0035295 125 0.055
female gamete generation GO:0007292 2 0.055
photoreceptor cell differentiation GO:0046530 2 0.055
regulation of protein localization GO:0032880 296 0.055
chromatin modification GO:0016568 298 0.054
positive regulation of proteolysis GO:0045862 142 0.054
neuron death GO:0070997 65 0.054
cytoplasmic transport GO:0016482 379 0.053
Yeast
cellular ketone metabolic process GO:0042180 80 0.053
regulation of microtubule cytoskeleton organization GO:0070507 61 0.052
response to interleukin 1 GO:0070555 47 0.052
cellular protein complex assembly GO:0043623 188 0.051
positive regulation of secretion by cell GO:1903532 108 0.051
circadian sleep wake cycle GO:0042745 2 0.049
regulation of growth GO:0040008 165 0.049
sequestering of calcium ion GO:0051208 17 0.049
response to alkaloid GO:0043279 20 0.049
cell recognition GO:0008037 9 0.049
Fly
response to nitrogen compound GO:1901698 184 0.049
cellular response to hydrogen peroxide GO:0070301 37 0.048
peptidyl serine phosphorylation GO:0018105 101 0.048
cation homeostasis GO:0055080 189 0.048
immune response GO:0006955 307 0.048
misfolded protein transport GO:0070843 1 0.047
positive regulation of apoptotic process GO:0043065 246 0.047
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.046
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.046
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.046
single organism reproductive process GO:0044702 98 0.045
long term synaptic potentiation GO:0060291 1 0.045
reproduction GO:0000003 63 0.044
Worm
neural tube formation GO:0001841 3 0.044
neuron projection morphogenesis GO:0048812 50 0.044
Fly
myeloid cell differentiation GO:0030099 117 0.044
response to organic cyclic compound GO:0014070 204 0.044
dna catabolic process GO:0006308 49 0.043
mitochondrial respiratory chain complex assembly GO:0033108 23 0.043
serotonin uptake GO:0051610 2 0.042
oxidation reduction process GO:0055114 396 0.042
chromatin organization GO:0006325 351 0.042
cellular lipid metabolic process GO:0044255 303 0.041
endosomal transport GO:0016197 129 0.041
Worm
cell cycle phase transition GO:0044770 173 0.040
negative regulation of hydrolase activity GO:0051346 182 0.040
system process GO:0003008 349 0.040
histone modification GO:0016570 251 0.040
embryonic morphogenesis GO:0048598 85 0.039
gtp metabolic process GO:0046039 239 0.039
positive regulation of phosphorylation GO:0042327 394 0.039
response to lithium ion GO:0010226 2 0.039
reproductive process GO:0022414 106 0.039
negative regulation of protein processing GO:0010955 142 0.039
response to inorganic substance GO:0010035 127 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.038
sex differentiation GO:0007548 45 0.038
cellular divalent inorganic cation homeostasis GO:0072503 128 0.037
blastoderm segmentation GO:0007350 2 0.037
defense response GO:0006952 315 0.037
enzyme linked receptor protein signaling pathway GO:0007167 303 0.037
protein targeting to nucleus GO:0044744 104 0.036
Yeast
primary neural tube formation GO:0014020 3 0.036
cellular chemical homeostasis GO:0055082 180 0.036
mitotic cell cycle phase transition GO:0044772 162 0.036
tissue migration GO:0090130 119 0.036
regulation of metal ion transport GO:0010959 120 0.035
embryonic placenta development GO:0001892 1 0.035
regulation of proteasomal protein catabolic process GO:0061136 87 0.035
calcium ion transport GO:0006816 147 0.035
mitotic cell cycle process GO:1903047 286 0.035
response to starvation GO:0042594 59 0.035
positive regulation of transport GO:0051050 336 0.034
protein targeting to mitochondrion GO:0006626 19 0.034
Yeast
oogenesis GO:0048477 2 0.034
ion homeostasis GO:0050801 230 0.034
oocyte development GO:0048599 1 0.034
regulation of glucocorticoid receptor signaling pathway GO:2000322 2 0.034
alcohol metabolic process GO:0006066 114 0.033
cellular response to oxidative stress GO:0034599 85 0.033
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.033
protein peptidyl prolyl isomerization GO:0000413 8 0.033
neuron apoptotic process GO:0051402 39 0.033
embryo development GO:0009790 123 0.032
Worm Fly
negative regulation of proteolysis GO:0045861 132 0.032
positive regulation of protein phosphorylation GO:0001934 313 0.032
locomotory behavior GO:0007626 1 0.032
positive regulation of cell death GO:0010942 263 0.032
peptidyl tyrosine modification GO:0018212 170 0.032
sequestering of metal ion GO:0051238 24 0.031
blood vessel development GO:0001568 172 0.031
divalent inorganic cation transport GO:0072511 158 0.031
myeloid cell homeostasis GO:0002262 34 0.031
regulation of response to oxidative stress GO:1902882 26 0.030
fatty acid metabolic process GO:0006631 115 0.030
protein processing GO:0016485 226 0.030
peptidyl tyrosine phosphorylation GO:0018108 170 0.030
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.030
rho protein signal transduction GO:0007266 26 0.030
head development GO:0060322 108 0.030
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.030
regulation of cell migration GO:0030334 289 0.029
intracellular receptor signaling pathway GO:0030522 104 0.029
centrosome organization GO:0051297 58 0.029
response to tumor necrosis factor GO:0034612 76 0.029
peptidyl lysine modification GO:0018205 144 0.029
regulation of circadian sleep wake cycle GO:0042749 2 0.029
regulation of secretion by cell GO:1903530 177 0.028
negative regulation of jun kinase activity GO:0043508 4 0.028
regulation of protein processing GO:0070613 150 0.028
regulation of gtpase activity GO:0043087 180 0.028
regulation of kinase activity GO:0043549 314 0.028
response to nutrient levels GO:0031667 81 0.027
cellular response to external stimulus GO:0071496 111 0.027
metal ion transport GO:0030001 272 0.027
regulation of protein catabolic process GO:0042176 155 0.027
endothelial cell migration GO:0043542 86 0.027
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.027
regulation of neuron death GO:1901214 56 0.027
mitochondrial membrane organization GO:0007006 40 0.027
internal peptidyl lysine acetylation GO:0018393 97 0.026
microtubule organizing center organization GO:0031023 62 0.026
cation transport GO:0006812 331 0.026
regulation of peptidyl serine phosphorylation GO:0033135 50 0.026
blood vessel morphogenesis GO:0048514 162 0.026
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
regulation of hormone levels GO:0010817 125 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
activation of mapkk activity GO:0000186 18 0.026
somitogenesis GO:0001756 2 0.026
leukocyte activation GO:0045321 164 0.026
response to misfolded protein GO:0051788 5 0.025
regulation of atp catabolic process GO:1903289 25 0.025
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.025
positive regulation of peptidase activity GO:0010952 88 0.025
regulation of postsynaptic membrane potential GO:0060078 1 0.025
ribonucleoprotein complex subunit organization GO:0071826 81 0.025
Yeast
regulation of blood vessel endothelial cell migration GO:0043535 30 0.025
hindbrain development GO:0030902 3 0.024
regulation of cellular protein catabolic process GO:1903362 96 0.024
response to other organism GO:0051707 261 0.024
positive regulation of gtpase activity GO:0043547 166 0.024
histone acetylation GO:0016573 93 0.024
positive regulation of atpase activity GO:0032781 19 0.024
mesendoderm development GO:0048382 1 0.024
cellular response to reactive oxygen species GO:0034614 50 0.024
regulation of body fluid levels GO:0050878 99 0.024
toxin transport GO:1901998 4 0.024
tripartite regional subdivision GO:0007351 2 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.023
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
carbohydrate metabolic process GO:0005975 207 0.023
somatic stem cell maintenance GO:0035019 4 0.023
tube morphogenesis GO:0035239 95 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.023
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.023
regulation of mapk cascade GO:0043408 262 0.023
zymogen activation GO:0031638 70 0.023
divalent metal ion transport GO:0070838 152 0.023
muscle structure development GO:0061061 98 0.023
regulation of intracellular transport GO:0032386 195 0.022
regulation of lipase activity GO:0060191 37 0.022
regulation of epithelial cell migration GO:0010632 93 0.022
anterior posterior axis specification GO:0009948 2 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
negative regulation of organelle organization GO:0010639 126 0.022
protein acetylation GO:0006473 116 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
cell division GO:0051301 168 0.021
spermatid differentiation GO:0048515 4 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.021
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
epithelial cell migration GO:0010631 119 0.021
negative regulation of protein kinase activity GO:0006469 98 0.021
cellular cation homeostasis GO:0030003 163 0.021
hormone metabolic process GO:0042445 61 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
response to mechanical stimulus GO:0009612 51 0.020
negative regulation of secretion GO:0051048 58 0.020
negative regulation of transport GO:0051051 176 0.020
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.020

HSPA1B disease predictions

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 68 0.373
cardiovascular system disease DOID:1287 106 0.373
myopathy DOID:423 104 0.189
muscular disease DOID:0080000 114 0.189
cardiomyopathy DOID:0050700 50 0.189
intrinsic cardiomyopathy DOID:0060036 50 0.189
musculoskeletal system disease DOID:17 223 0.189
muscle tissue disease DOID:66 113 0.189
dilated cardiomyopathy DOID:12930 32 0.166
neuromuscular disease DOID:440 38 0.126
charcot marie tooth disease DOID:10595 33 0.126
nervous system disease DOID:863 431 0.126
neuropathy DOID:870 52 0.126
central nervous system disease DOID:331 186 0.072
neurodegenerative disease DOID:1289 102 0.062
parkinson s disease DOID:14330 18 0.036
synucleinopathy DOID:0050890 22 0.036
disease of mental health DOID:150 70 0.026
charcot marie tooth disease type 2 DOID:0050539 15 0.025
gastrointestinal system disease DOID:77 36 0.022