IMP

Process View

Homo sapiens

17 genes annotated in human

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regulation of erythrocyte differentiation

GO:0045646

Any process that modulates the frequency, rate or extent of erythrocyte differentiation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of erythrocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of erythrocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
CREBBP	CREB binding protein	0.998
TAL1	T-cell acute lymphocytic leukemia 1	0.997
HSPA1B	heat shock 70kDa protein 1B	0.978
RUNX1	runt-related transcription factor 1	0.937
KAT2B	K(lysine) acetyltransferase 2B	0.916
SMAD7	SMAD family member 7	0.853
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.829
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.799
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.797	Mouse
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.795
HSPA1A	heat shock 70kDa protein 1A	0.790
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.780
CCND1	cyclin D1	0.745
GATA2	GATA binding protein 2	0.734	Human Mouse
HOXA10	homeobox A10	0.697
HOXB5	homeobox B5	0.670	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.636	Human
FKBP1A	FK506 binding protein 1A, 12kDa	0.586
BMP2	bone morphogenetic protein 2	0.568
AR	androgen receptor	0.528
NCOA1	nuclear receptor coactivator 1	0.478
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.439
JUN	jun proto-oncogene	0.429
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.429
PPP5C	protein phosphatase 5, catalytic subunit	0.428
TP53	tumor protein p53	0.427
TGFB1	transforming growth factor, beta 1	0.423
CDK2	cyclin-dependent kinase 2	0.362
HSPH1	heat shock 105kDa/110kDa protein 1	0.266
NCOA6	nuclear receptor coactivator 6	0.259
NCOA2	nuclear receptor coactivator 2	0.253
HOXA5	homeobox A5	0.244
CDK6	cyclin-dependent kinase 6	0.224
CCND3	cyclin D3	0.220
KLF13	Kruppel-like factor 13	0.190	Mouse
EP300	E1A binding protein p300	0.187
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.176
HOXB6	homeobox B6	0.168	Human
DAXX	death-domain associated protein	0.160
ENG	endoglin	0.151
SETD8	SET domain containing (lysine methyltransferase) 8	0.150
BAG3	BCL2-associated athanogene 3	0.149
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.149
RBBP4	retinoblastoma binding protein 4	0.144
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.143
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.139	Human
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.128
RB1	retinoblastoma 1	0.119
HOXB3	homeobox B3	0.114
RXRA	retinoid X receptor, alpha	0.108
PRMT6	protein arginine methyltransferase 6	0.108
HOXB7	homeobox B7	0.102	Human
ESR1	estrogen receptor 1	0.100
SMAD2	SMAD family member 2	0.097
LMO4	LIM domain only 4	0.094
HOXA7	homeobox A7	0.093	Human
ACVR1	activin A receptor, type I	0.091	Human
GATA4	GATA binding protein 4	0.088	Human
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.088
BMPR1A	bone morphogenetic protein receptor, type IA	0.081	Human
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.075
HDAC2	histone deacetylase 2	0.070
HOXB9	homeobox B9	0.064
GDF5	growth differentiation factor 5	0.062
INSR	insulin receptor	0.060
HOXA4	homeobox A4	0.057	Human
SP1	Sp1 transcription factor	0.057
TCF12	transcription factor 12	0.056
EPOR	erythropoietin receptor	0.054
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.051
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.051
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.050
AHR	aryl hydrocarbon receptor	0.043
HDAC1	histone deacetylase 1	0.043
RFWD2	ring finger and WD repeat domain 2	0.043
PRKG1	protein kinase, cGMP-dependent, type I	0.042
HOXC6	homeobox C6	0.041	Human
PTMA	prothymosin, alpha	0.040
HMGA1	high mobility group AT-hook 1	0.040
SP100	SP100 nuclear antigen	0.039
PDX1	pancreatic and duodenal homeobox 1	0.039
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.038
TBX5	T-box 5	0.038
NFIL3	nuclear factor, interleukin 3 regulated	0.037
LMO2	LIM domain only 2 (rhombotin-like 1)	0.035	Mouse
HOXA2	homeobox A2	0.035
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.035
BAG1	BCL2-associated athanogene	0.034
MTA3	metastasis associated 1 family, member 3	0.034
HOXA6	homeobox A6	0.034	Human
DDIT3	DNA-damage-inducible transcript 3	0.034
CCND2	cyclin D2	0.034
IRS2	insulin receptor substrate 2	0.033
FSTL1	follistatin-like 1	0.033
TWIST2	twist homolog 2 (Drosophila)	0.032
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.032
HOXC10	homeobox C10	0.032
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.032
HIPK2	homeodomain interacting protein kinase 2	0.031
HTT	huntingtin	0.031
LYL1	lymphoblastic leukemia derived sequence 1	0.031	Human
CDCA8	cell division cycle associated 8	0.030
HMGB1	high mobility group box 1	0.030	Human
MAPK8	mitogen-activated protein kinase 8	0.030
VEGFA	vascular endothelial growth factor A	0.028
HOXA11	homeobox A11	0.028
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.027
HSF1	heat shock transcription factor 1	0.027
CREB1	cAMP responsive element binding protein 1	0.027
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.025	Human
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.024
CUX1	cut-like homeobox 1	0.024
RCC1	regulator of chromosome condensation 1	0.022
MYOD1	myogenic differentiation 1	0.022
HOXA3	homeobox A3	0.022
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.021
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.020
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.020
IFIT1	interferon-induced protein with tetratricopeptide repeats 1	0.019
HOXD12	homeobox D12	0.019
USPL1	ubiquitin specific peptidase like 1	0.018
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.018
TGFB3	transforming growth factor, beta 3	0.018
JAK2	Janus kinase 2	0.018
CCNE1	cyclin E1	0.018
RLIM	ring finger protein, LIM domain interacting	0.017
HMGN2	high mobility group nucleosomal binding domain 2	0.017
LDLR	low density lipoprotein receptor	0.017
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.017
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.016
VIM	vimentin	0.016
HOXC4	homeobox C4	0.016	Human
TWIST1	twist homolog 1 (Drosophila)	0.016	Human
STAP2	signal transducing adaptor family member 2	0.016
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.016
IRF3	interferon regulatory factor 3	0.016
GSK3B	glycogen synthase kinase 3 beta	0.016
USP18	ubiquitin specific peptidase 18	0.015
PHOX2A	paired-like homeobox 2a	0.015
SFRP5	secreted frizzled-related protein 5	0.015
HOXC11	homeobox C11	0.014
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.014
AURKB	aurora kinase B	0.014
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.014
NCOA3	nuclear receptor coactivator 3	0.013
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.013
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.013
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.013
JAG2	jagged 2	0.013
GHR	growth hormone receptor	0.013
ACVR1B	activin A receptor, type IB	0.012
HOXB2	homeobox B2	0.012
BMP4	bone morphogenetic protein 4	0.012
DUSP5	dual specificity phosphatase 5	0.012
ATF3	activating transcription factor 3	0.012
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.012
FOXD3	forkhead box D3	0.012
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.012
HOXB13	homeobox B13	0.011
SMAD6	SMAD family member 6	0.011
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.011
HOXC8	homeobox C8	0.011	Human
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
DEK	DEK oncogene	0.011
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.011
POU2F2	POU class 2 homeobox 2	0.011
FHL2	four and a half LIM domains 2	0.011
PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285	0.011
ZFPM1	zinc finger protein, multitype 1	0.011
HOXB4	homeobox B4	0.011	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.010
GLIS2	GLIS family zinc finger 2	0.010
NEUROG1	neurogenin 1	0.010	Human
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.010
HOXC5	homeobox C5	0.010	Human
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.010
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.010
MEOX2	mesenchyme homeobox 2	0.010