Homo sapiens

135 known processes

HSPB1

heat shock 27kDa protein 1

(Aliases: HMN2B,HS.76067,SRP27,DKFZp586P1322,CMT2F,HSP27,Hsp25,HSP28)

HSPB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of light stimulus GO:0050953 35 0.999
determination of adult lifespan GO:0008340 2 0.996
Worm Fly
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.995
visual perception GO:0007601 27 0.990
response to abiotic stimulus GO:0009628 336 0.960
Zebrafish Fly
cellular response to abiotic stimulus GO:0071214 117 0.949
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.943
response to bacterium GO:0009617 144 0.943
defense response to bacterium GO:0042742 63 0.888
cellular response to oxidative stress GO:0034599 85 0.882
Mouse
cellular response to radiation GO:0071478 65 0.875
cellular response to growth factor stimulus GO:0071363 197 0.861
defense response to other organism GO:0098542 129 0.856
post embryonic development GO:0009791 2 0.840
negative regulation of programmed cell death GO:0043069 321 0.826
Mouse
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.819
response to heat GO:0009408 21 0.794
Zebrafish
negative regulation of cell death GO:0060548 345 0.789
Mouse
multicellular organismal aging GO:0010259 3 0.782
Worm Fly
protein oligomerization GO:0051259 173 0.769
ras protein signal transduction GO:0007265 73 0.761
system process GO:0003008 349 0.754
Zebrafish
response to oxidative stress GO:0006979 121 0.735
Mouse
defense response to fungus GO:0050832 4 0.731
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.728
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.723
response to growth factor GO:0070848 205 0.715
nucleoside triphosphate metabolic process GO:0009141 422 0.689
glutathione metabolic process GO:0006749 20 0.688
response to fungus GO:0009620 4 0.679
response to estrogen GO:0043627 47 0.677
negative regulation of apoptotic process GO:0043066 316 0.667
Mouse
positive regulation of developmental process GO:0051094 314 0.663
vasculature development GO:0001944 181 0.647
defense response GO:0006952 315 0.641
biological adhesion GO:0022610 331 0.635
mapk cascade GO:0000165 288 0.630
cellular response to ionizing radiation GO:0071479 32 0.624
circulatory system development GO:0072359 262 0.620
response to radiation GO:0009314 151 0.609
response to external biotic stimulus GO:0043207 261 0.595
cellular amino acid metabolic process GO:0006520 116 0.575
signal transduction by phosphorylation GO:0023014 297 0.573
cellular response to gamma radiation GO:0071480 8 0.559
regulation of cell migration GO:0030334 289 0.556
blood vessel morphogenesis GO:0048514 162 0.517
response to hypoxia GO:0001666 96 0.511
ribonucleoside triphosphate metabolic process GO:0009199 412 0.503
negative regulation of transport GO:0051051 176 0.494
response to other organism GO:0051707 261 0.472
nucleotide catabolic process GO:0009166 408 0.468
response to ionizing radiation GO:0010212 65 0.447
regulation of jnk cascade GO:0046328 73 0.443
response to oxygen containing compound GO:1901700 369 0.442
negative regulation of protein modification process GO:0031400 200 0.439
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.438
nervous system development GO:0007399 293 0.437
small gtpase mediated signal transduction GO:0007264 78 0.428
purine containing compound catabolic process GO:0072523 411 0.426
regulation of cellular response to stress GO:0080135 244 0.425
Mouse
positive regulation of cell migration by vascular endothelial growth factor signaling pathway GO:0038089 5 0.411
ribonucleoside catabolic process GO:0042454 406 0.405
negative regulation of cell proliferation GO:0008285 228 0.403
purine nucleoside triphosphate catabolic process GO:0009146 392 0.398
regulation of endothelial cell chemotaxis GO:2001026 9 0.396
aging GO:0007568 66 0.391
Worm Fly
response to lipid GO:0033993 206 0.391
steroid metabolic process GO:0008202 94 0.383
response to temperature stimulus GO:0009266 22 0.380
Zebrafish Fly
response to gamma radiation GO:0010332 14 0.377
regulation of cell growth GO:0001558 135 0.374
response to topologically incorrect protein GO:0035966 29 0.371
response to biotic stimulus GO:0009607 276 0.370
cardiovascular system development GO:0072358 262 0.364
purine nucleoside catabolic process GO:0006152 398 0.362
embryonic placenta development GO:0001892 1 0.356
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.353
apoptotic signaling pathway GO:0097190 268 0.352
Mouse
oxidation reduction process GO:0055114 396 0.347
regulation of locomotion GO:0040012 329 0.344
endothelial cell migration GO:0043542 86 0.342
nucleoside catabolic process GO:0009164 408 0.330
positive regulation of epithelial cell migration GO:0010634 55 0.329
cellular senescence GO:0090398 34 0.322
vesicle mediated transport GO:0016192 371 0.322
angiogenesis GO:0001525 147 0.317
positive regulation of endothelial cell migration GO:0010595 39 0.315
cell adhesion GO:0007155 325 0.307
purine ribonucleoside metabolic process GO:0046128 437 0.306
response to wounding GO:0009611 168 0.304
cell activation GO:0001775 213 0.299
steroid biosynthetic process GO:0006694 46 0.299
stress activated mapk cascade GO:0051403 93 0.297
growth GO:0040007 202 0.296
response to extracellular stimulus GO:0009991 85 0.291
regulation of cell morphogenesis GO:0022604 153 0.284
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.284
lipid metabolic process GO:0006629 381 0.280
negative regulation of protein metabolic process GO:0051248 391 0.277
Mouse
wound healing GO:0042060 115 0.275
regulation of wnt signaling pathway GO:0030111 123 0.273
purine ribonucleotide catabolic process GO:0009154 404 0.260
response to organic cyclic compound GO:0014070 204 0.259
ribonucleotide catabolic process GO:0009261 405 0.258
regulation of anatomical structure morphogenesis GO:0022603 286 0.258
cellular modified amino acid metabolic process GO:0006575 64 0.253
cofactor metabolic process GO:0051186 87 0.252
glycosyl compound catabolic process GO:1901658 413 0.250
response to oxygen levels GO:0070482 100 0.247
regulation of anatomical structure size GO:0090066 101 0.244
Zebrafish
dna damage checkpoint GO:0000077 68 0.242
cellular protein catabolic process GO:0044257 261 0.237
erythrocyte development GO:0048821 3 0.237
purine nucleoside triphosphate metabolic process GO:0009144 412 0.231
ubiquitin dependent protein catabolic process GO:0006511 206 0.230
cytokine production GO:0001816 247 0.229
Mouse
regulation of striated muscle cell apoptotic process GO:0010662 3 0.229
cellular macromolecular complex assembly GO:0034622 324 0.228
sensory perception GO:0007600 103 0.228
actin cytoskeleton organization GO:0030036 207 0.228
response to alcohol GO:0097305 64 0.224
signal transduction in absence of ligand GO:0038034 22 0.220
erythrocyte maturation GO:0043249 1 0.218
epiboly involved in gastrulation with mouth forming second GO:0055113 1 0.217
positive regulation of phosphorylation GO:0042327 394 0.214
stress activated protein kinase signaling cascade GO:0031098 94 0.211
single organismal cell cell adhesion GO:0016337 148 0.210
cell cycle checkpoint GO:0000075 117 0.209
cellular response to tumor necrosis factor GO:0071356 63 0.205
positive regulation of hydrolase activity GO:0051345 331 0.202
positive regulation of mapk cascade GO:0043410 190 0.201
nucleoside triphosphate catabolic process GO:0009143 394 0.199
modification dependent protein catabolic process GO:0019941 209 0.196
protein homooligomerization GO:0051260 100 0.196
cellular response to endogenous stimulus GO:0071495 336 0.192
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.191
cellular component morphogenesis GO:0032989 314 0.186
response to unfolded protein GO:0006986 24 0.185
cellular response to oxygen containing compound GO:1901701 276 0.185
positive regulation of catabolic process GO:0009896 310 0.184
lipid biosynthetic process GO:0008610 177 0.181
sulfur compound metabolic process GO:0006790 101 0.180
regulation of growth GO:0040008 165 0.179
macropinocytosis GO:0044351 1 0.178
response to reactive oxygen species GO:0000302 61 0.176
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.175
negative regulation of cell growth GO:0030308 83 0.171
positive regulation of nucleotide catabolic process GO:0030813 185 0.171
neurological system process GO:0050877 163 0.168
cell aging GO:0007569 52 0.167
muscle structure development GO:0061061 98 0.166
regulation of stress activated mapk cascade GO:0032872 84 0.166
gtp catabolic process GO:0006184 237 0.163
regulation of nucleoside metabolic process GO:0009118 209 0.162
regulation of body fluid levels GO:0050878 99 0.162
regulation of tumor necrosis factor production GO:0032680 43 0.162
Mouse
organelle fission GO:0048285 149 0.162
response to decreased oxygen levels GO:0036293 96 0.160
response to nutrient levels GO:0031667 81 0.159
positive regulation of cellular amine metabolic process GO:0033240 7 0.158
regulation of apoptotic signaling pathway GO:2001233 175 0.153
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.153
response to starvation GO:0042594 59 0.151
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.149
mrna metabolic process GO:0016071 175 0.148
rna stabilization GO:0043489 18 0.146
regulation of cellular component movement GO:0051270 334 0.144
cell type specific apoptotic process GO:0097285 125 0.144
regulation of intracellular transport GO:0032386 195 0.143
g2 dna damage checkpoint GO:0031572 26 0.142
response to mechanical stimulus GO:0009612 51 0.141
peptidyl serine modification GO:0018209 106 0.141
blood vessel development GO:0001568 172 0.141
purine nucleotide catabolic process GO:0006195 405 0.137
hematopoietic or lymphoid organ development GO:0048534 186 0.136
positive regulation of cellular component movement GO:0051272 181 0.136
ribonucleoside monophosphate metabolic process GO:0009161 187 0.136
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.135
Mouse
carbohydrate metabolic process GO:0005975 207 0.134
platelet aggregation GO:0070527 32 0.133
response to hydrogen peroxide GO:0042542 40 0.129
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.129
neuron differentiation GO:0030182 138 0.123
cellular response to cytokine stimulus GO:0071345 181 0.123
cellular response to topologically incorrect protein GO:0035967 19 0.123
positive regulation of cell migration GO:0030335 172 0.122
regulation of nucleotide metabolic process GO:0006140 269 0.120
ribonucleoside monophosphate catabolic process GO:0009158 158 0.119
organophosphate catabolic process GO:0046434 430 0.117
regulation of mapk cascade GO:0043408 262 0.115
protein modification by small protein conjugation GO:0032446 342 0.115
protein stabilization GO:0050821 64 0.115
purine nucleoside monophosphate metabolic process GO:0009126 186 0.114
striated muscle cell differentiation GO:0051146 43 0.114
microtubule polymerization or depolymerization GO:0031109 37 0.111
positive regulation of cellular catabolic process GO:0031331 284 0.110
retina homeostasis GO:0001895 42 0.108
cellular amine metabolic process GO:0044106 41 0.107
enzyme linked receptor protein signaling pathway GO:0007167 303 0.107
amine metabolic process GO:0009308 44 0.106
cellular response to heat GO:0034605 14 0.106
cellular response to mechanical stimulus GO:0071260 39 0.105
positive regulation of cellular component organization GO:0051130 376 0.105
regulation of cellular amine metabolic process GO:0033238 11 0.105
dna repair GO:0006281 198 0.105
vasodilation GO:0042311 4 0.105
jnk cascade GO:0007254 80 0.105
response to virus GO:0009615 126 0.104
activation of innate immune response GO:0002218 55 0.103
tumor necrosis factor production GO:0032640 43 0.103
Mouse
purine ribonucleoside catabolic process GO:0046130 398 0.102
single organism carbohydrate metabolic process GO:0044723 193 0.097
platelet activation GO:0030168 44 0.096
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.096
receptor mediated endocytosis GO:0006898 84 0.095
blood circulation GO:0008015 113 0.092
endocytosis GO:0006897 159 0.090
pattern recognition receptor signaling pathway GO:0002221 48 0.089
pinocytosis GO:0006907 8 0.088
cellular response to external stimulus GO:0071496 111 0.088
small molecule biosynthetic process GO:0044283 157 0.087
nuclear division GO:0000280 128 0.086
reactive oxygen species metabolic process GO:0072593 75 0.086
wnt signaling pathway GO:0016055 156 0.085
striated muscle cell development GO:0055002 27 0.085
positive regulation of nucleotide metabolic process GO:0045981 230 0.084
mitotic cell cycle process GO:1903047 286 0.083
positive regulation of transferase activity GO:0051347 227 0.083
actin filament based process GO:0030029 224 0.080
innate immune response GO:0045087 178 0.079
interleukin 6 production GO:0032635 37 0.079
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.079
membrane organization GO:0061024 292 0.077
nucleoside phosphate biosynthetic process GO:1901293 109 0.076
ribonucleoside triphosphate catabolic process GO:0009203 391 0.076
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.075
guanosine containing compound metabolic process GO:1901068 244 0.075
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.075
response to inorganic substance GO:0010035 127 0.075
cell development GO:0048468 328 0.074
atp catabolic process GO:0006200 157 0.074
locomotory behavior GO:0007626 1 0.074
immune response activating signal transduction GO:0002757 90 0.074
protein ubiquitination GO:0016567 314 0.073
coenzyme metabolic process GO:0006732 65 0.072
nucleoside phosphate catabolic process GO:1901292 412 0.071
regulation of nucleotide catabolic process GO:0030811 205 0.071
sterol metabolic process GO:0016125 28 0.071
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.071
Mouse
response to salt stress GO:0009651 3 0.070
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.070
regulation of cell cycle process GO:0010564 266 0.070
cell morphogenesis GO:0000902 296 0.069
histone modification GO:0016570 251 0.069
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.068
central nervous system development GO:0007417 123 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.068
divalent metal ion transport GO:0070838 152 0.066
response to hormone GO:0009725 175 0.065
response to molecule of bacterial origin GO:0002237 82 0.065
tube morphogenesis GO:0035239 95 0.065
immune response GO:0006955 307 0.065
protein catabolic process GO:0030163 325 0.064
negative regulation of cytokine production GO:0001818 82 0.064
divalent inorganic cation transport GO:0072511 158 0.064
cellular response to reactive oxygen species GO:0034614 50 0.063
regulation of response to external stimulus GO:0032101 222 0.063
cellular response to organic cyclic compound GO:0071407 127 0.063
alcohol metabolic process GO:0006066 114 0.063
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.063
microtubule cytoskeleton organization GO:0000226 176 0.063
regulation of cellular ketone metabolic process GO:0010565 50 0.062
female gamete generation GO:0007292 2 0.062
intrinsic apoptotic signaling pathway GO:0097193 127 0.062
Mouse
regulation of cytokine production GO:0001817 232 0.060
Mouse
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.060
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.060
organonitrogen compound biosynthetic process GO:1901566 200 0.060
behavior GO:0007610 112 0.060
protein targeting to nucleus GO:0044744 104 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
regulation of innate immune response GO:0045088 97 0.059
organic hydroxy compound biosynthetic process GO:1901617 71 0.059
endomembrane system organization GO:0010256 196 0.058
regulation of cell shape GO:0008360 48 0.057
regulation of chemotaxis GO:0050920 74 0.057
glucose metabolic process GO:0006006 45 0.056
regulation of cell motility GO:2000145 299 0.056
epithelial cell migration GO:0010631 119 0.055
regulation of defense response GO:0031347 154 0.055
regulation of cell cycle GO:0051726 393 0.055
cellular ketone metabolic process GO:0042180 80 0.055
erk1 and erk2 cascade GO:0070371 104 0.054
dna integrity checkpoint GO:0031570 71 0.054
tissue homeostasis GO:0001894 63 0.054
regulation of binding GO:0051098 111 0.053
embryo development GO:0009790 123 0.053
negative regulation of systemic arterial blood pressure GO:0003085 1 0.053
regulation of immune response GO:0050776 201 0.053
negative regulation of growth GO:0045926 97 0.053
protein refolding GO:0042026 14 0.053
positive regulation of organelle organization GO:0010638 195 0.053
gonad development GO:0008406 34 0.053
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.052
regulation of metal ion transport GO:0010959 120 0.052
posttranscriptional regulation of gene expression GO:0010608 213 0.052
translation GO:0006412 132 0.051
regulation of reactive oxygen species metabolic process GO:2000377 41 0.051
regulation of protein ubiquitination GO:0031396 95 0.051
coenzyme biosynthetic process GO:0009108 24 0.051
peptidyl serine phosphorylation GO:0018105 101 0.051
single organism cell adhesion GO:0098602 179 0.051
extrinsic apoptotic signaling pathway GO:0097191 119 0.049
regulation of ubiquitin protein transferase activity GO:0051438 28 0.049
positive regulation of wnt signaling pathway GO:0030177 54 0.048
cellular protein complex assembly GO:0043623 188 0.048
regulation of transmembrane transport GO:0034762 139 0.048
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.047
immune system development GO:0002520 195 0.047
regulation of gtp catabolic process GO:0033124 180 0.047
regulation of cellular component size GO:0032535 82 0.046
negative regulation of apoptotic signaling pathway GO:2001234 97 0.046
Mouse
spinal cord development GO:0021510 4 0.045
regulation of protein catabolic process GO:0042176 155 0.045
positive regulation of cell development GO:0010720 92 0.045
cellular response to misfolded protein GO:0071218 2 0.045
organic hydroxy compound metabolic process GO:1901615 147 0.045
positive regulation of meiotic cell cycle GO:0051446 2 0.045
neural nucleus development GO:0048857 47 0.044
cellular macromolecule catabolic process GO:0044265 380 0.044
regulation of synaptic plasticity GO:0048167 3 0.044
head development GO:0060322 108 0.044
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.044
regulation of epithelial cell proliferation GO:0050678 113 0.043
nucleotide biosynthetic process GO:0009165 109 0.043
brain development GO:0007420 97 0.043
carbohydrate biosynthetic process GO:0016051 42 0.043
protein folding GO:0006457 38 0.043
single organism reproductive process GO:0044702 98 0.043
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.042
positive regulation of growth GO:0045927 58 0.042
purine nucleoside monophosphate catabolic process GO:0009128 158 0.042
covalent chromatin modification GO:0016569 254 0.042
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.042
striated muscle cell apoptotic process GO:0010658 3 0.042
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.042
microtubule based process GO:0007017 210 0.041
response to steroid hormone GO:0048545 80 0.041
regulation of transporter activity GO:0032409 82 0.041
homeostasis of number of cells GO:0048872 40 0.041
negative regulation of cellular catabolic process GO:0031330 83 0.041
regulation of ion transport GO:0043269 189 0.039
regulation of cell development GO:0060284 161 0.039
negative regulation of organelle organization GO:0010639 126 0.039
protein maturation GO:0051604 233 0.039
carbohydrate catabolic process GO:0016052 36 0.039
regulation of calcium ion transport GO:0051924 79 0.039
activation of immune response GO:0002253 114 0.039
ameboidal type cell migration GO:0001667 135 0.039
cation transport GO:0006812 331 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
Mouse
developmental growth GO:0048589 48 0.038
chromatin modification GO:0016568 298 0.038
regulation of behavior GO:0050795 82 0.038
proteasomal protein catabolic process GO:0010498 176 0.038
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.038
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.038
regulation of cellular response to growth factor stimulus GO:0090287 76 0.037
cofactor biosynthetic process GO:0051188 31 0.037
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.037
positive regulation of immune system process GO:0002684 283 0.037
regulation of ion transmembrane transport GO:0034765 132 0.036
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.036
regulation of protein kinase activity GO:0045859 289 0.036
Mouse
striated muscle myosin thick filament assembly GO:0071688 2 0.036
anatomical structure formation involved in morphogenesis GO:0048646 284 0.036
transmembrane transport GO:0055085 399 0.036
positive regulation of cell proliferation GO:0008284 301 0.036
establishment of protein localization to organelle GO:0072594 172 0.036
hemostasis GO:0007599 76 0.035
sequestering of metal ion GO:0051238 24 0.035
positive regulation of protein phosphorylation GO:0001934 313 0.035
cellular component assembly involved in morphogenesis GO:0010927 73 0.034
oocyte differentiation GO:0009994 2 0.034
regulation of vasculature development GO:1901342 97 0.034
anatomical structure homeostasis GO:0060249 100 0.034
nucleoside monophosphate metabolic process GO:0009123 191 0.034
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.034
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.033
cellular response to lipid GO:0071396 127 0.033
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
neurogenesis GO:0022008 169 0.033
embryo development ending in birth or egg hatching GO:0009792 34 0.033
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.032
regulation of chromatin modification GO:1903308 51 0.032
mitotic cell cycle checkpoint GO:0007093 68 0.032
cytokine mediated signaling pathway GO:0019221 109 0.032
positive regulation of nucleoside metabolic process GO:0045979 186 0.032
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.031
protein import GO:0017038 130 0.031
negative regulation of endopeptidase activity GO:0010951 84 0.031
regulation of transferase activity GO:0051338 355 0.031
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.031
regulation of actin filament based process GO:0032970 141 0.030
peptide metabolic process GO:0006518 51 0.030
golgi organization GO:0007030 38 0.030
cellular lipid metabolic process GO:0044255 303 0.030
cytoplasmic transport GO:0016482 379 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.030
cell division GO:0051301 168 0.030
ribonucleoprotein complex disassembly GO:0032988 7 0.030
regulation of gtpase activity GO:0043087 180 0.030
negative regulation of protein maturation GO:1903318 142 0.030
embryonic organ development GO:0048568 36 0.030
neurotransmitter secretion GO:0007269 4 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
response to light stimulus GO:0009416 87 0.029
mitotic cell cycle phase transition GO:0044772 162 0.029
positive regulation of cell cycle process GO:0090068 106 0.029
rho protein signal transduction GO:0007266 26 0.029
regulation of peptidase activity GO:0052547 180 0.029
protein targeting GO:0006605 187 0.029
regulation of small gtpase mediated signal transduction GO:0051056 156 0.029
monosaccharide metabolic process GO:0005996 74 0.029
cellular amide metabolic process GO:0043603 69 0.029
positive regulation of gtp catabolic process GO:0033126 166 0.029
cellular homeostasis GO:0019725 196 0.029
positive regulation of cell differentiation GO:0045597 211 0.029
cellular component disassembly GO:0022411 92 0.029
protein deubiquitination GO:0016579 79 0.028
ion transmembrane transport GO:0034220 338 0.028
alcohol biosynthetic process GO:0046165 52 0.028
regulation of dna metabolic process GO:0051052 153 0.028
midbrain development GO:0030901 45 0.028
regulation of rho protein signal transduction GO:0035023 79 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
protein import into nucleus GO:0006606 104 0.027
digestive tract development GO:0048565 75 0.027
embryonic morphogenesis GO:0048598 85 0.027
protein processing GO:0016485 226 0.027
positive regulation of protein ubiquitination GO:0031398 53 0.027
maintenance of location GO:0051235 112 0.027
regulation of cell division GO:0051302 116 0.027
gtp metabolic process GO:0046039 239 0.027
response to tumor necrosis factor GO:0034612 76 0.027
endocrine process GO:0050886 25 0.027
regulation of multicellular organism growth GO:0040014 8 0.027
skin development GO:0043588 76 0.027
regulation of cytoskeleton organization GO:0051493 177 0.027
meiotic cell cycle GO:0051321 13 0.026
erythrocyte homeostasis GO:0034101 31 0.026
atp metabolic process GO:0046034 176 0.026
tube development GO:0035295 125 0.026
regulation of translation GO:0006417 89 0.026
response to xenobiotic stimulus GO:0009410 30 0.026
regulation of actin cytoskeleton organization GO:0032956 116 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
membrane lipid metabolic process GO:0006643 53 0.026
cytosolic calcium ion transport GO:0060401 48 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
Mouse
vitamin d receptor signaling pathway GO:0070561 4 0.025
vasoconstriction GO:0042310 11 0.025
regulation of epithelial cell migration GO:0010632 93 0.025
positive regulation of dendrite morphogenesis GO:0050775 3 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
inflammatory response GO:0006954 79 0.025
actin filament organization GO:0007015 128 0.025
cellular response to organonitrogen compound GO:0071417 124 0.025
guanosine containing compound catabolic process GO:1901069 239 0.025

HSPB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.996
myopathy DOID:423 104 0.995
muscular disease DOID:0080000 114 0.995
heart disease DOID:114 68 0.995
cardiomyopathy DOID:0050700 50 0.995
musculoskeletal system disease DOID:17 223 0.995
muscle tissue disease DOID:66 113 0.995
dilated cardiomyopathy DOID:12930 32 0.983
intrinsic cardiomyopathy DOID:0060036 50 0.983
neuromuscular disease DOID:440 38 0.806
charcot marie tooth disease type 2 DOID:0050539 15 0.806
charcot marie tooth disease DOID:10595 33 0.806
nervous system disease DOID:863 431 0.806
neuropathy DOID:870 52 0.806
sensory system disease DOID:0050155 203 0.636
eye and adnexa disease DOID:1492 150 0.636
eye disease DOID:5614 149 0.636
motor neuron disease DOID:231 27 0.377
distal hereditary motor neuropathy DOID:0050582 5 0.377
central nervous system disease DOID:331 186 0.377
motor neuritis DOID:683 5 0.377
neurodegenerative disease DOID:1289 102 0.377
disease of cellular proliferation DOID:14566 174 0.065
cancer DOID:162 167 0.037
organ system cancer DOID:0050686 164 0.037