|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.869
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.776
|
Fly |
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.731
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.705
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.696
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.641
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.625
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.584
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.562
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.555
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.545
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.530
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.513
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.512
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.501
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.461
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.450
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.426
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.421
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.411
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.400
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.392
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.385
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.384
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.381
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.368
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.352
|
Mouse |
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
1 |
0.348
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.347
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.346
|
|
|
|
immunoglobulin biosynthetic process
|
GO:0002378 |
2 |
0.341
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.340
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.338
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.333
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.319
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.318
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.301
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.294
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.292
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.289
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.288
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.282
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.268
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.261
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.261
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.255
|
Human Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.254
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.249
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.241
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.238
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.238
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.237
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.235
|
Mouse |
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.234
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.233
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.229
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.228
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.227
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.223
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.221
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
1 |
0.215
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.208
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.208
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.206
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.205
|
Fly |
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.204
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.203
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.201
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.195
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.193
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.193
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.192
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.191
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.191
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.191
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.190
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.190
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.189
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.189
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.186
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.185
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.181
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.174
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.174
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.174
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.172
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.165
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.163
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.161
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.159
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.157
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.156
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.156
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.153
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.152
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.150
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.150
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.148
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.148
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.147
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.147
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.146
|
Mouse |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.145
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.145
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.144
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.142
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.142
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.140
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.138
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.135
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.134
|
Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.134
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.132
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.131
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.128
|
Human |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.126
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.126
|
|
|
|
positive regulation of collateral sprouting
|
GO:0048672 |
2 |
0.123
|
|
|
|
drinking behavior
|
GO:0042756 |
1 |
0.120
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.120
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.118
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.118
|
Human Fly |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.118
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.118
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.117
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.117
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.116
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.115
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.115
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.115
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.111
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.111
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.111
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.111
|
Mouse |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.111
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.110
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.109
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.108
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.108
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.108
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.107
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.107
|
Human Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.106
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.105
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.104
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.103
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.103
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.102
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.102
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.100
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.098
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.098
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.097
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.096
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
19 |
0.092
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.092
|
Mouse |
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.091
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.090
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.090
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.090
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.089
|
Fly |
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.089
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.088
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.087
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.086
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.085
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.084
|
|
|
|
bone marrow development
|
GO:0048539 |
3 |
0.083
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.083
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.083
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.083
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.083
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.083
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.081
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.081
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.081
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.080
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.080
|
Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.079
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.078
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.076
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.076
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.074
|
Fly |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.074
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.074
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.074
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.074
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.071
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.071
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.071
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.070
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.069
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.068
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.066
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.066
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.066
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.066
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.066
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.065
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.065
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.064
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.063
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.062
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.062
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.061
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.061
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.061
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.060
|
Mouse |
|
|
nervous system development
|
GO:0007399 |
293 |
0.059
|
Fly |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.059
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.059
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.059
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.059
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.059
|
Human |
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
1 |
0.058
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.058
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.058
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.058
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.058
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.057
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.057
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.057
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.056
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.056
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.056
|
Fly |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.056
|
Mouse |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.056
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.056
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.055
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.055
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.054
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
4 |
0.054
|
|
|
|
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:0002291 |
4 |
0.053
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.053
|
Human |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.052
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.052
|
Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.052
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.052
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.051
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.051
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.050
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.050
|
Human Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.050
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.050
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.049
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.049
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.049
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.049
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.048
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
1 |
0.048
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.048
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.048
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.048
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.048
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
23 |
0.047
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.047
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.047
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.047
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.047
|
Human |
|
|
t cell mediated immunity
|
GO:0002456 |
25 |
0.046
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.046
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.046
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.046
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.045
|
Human |
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.045
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.044
|
Human Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.044
|
Human |
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.044
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.044
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
2 |
0.043
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.043
|
Human |
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.043
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.042
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.042
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.042
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.042
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.042
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.042
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.041
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.041
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.041
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.040
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.040
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.040
|
|
|
|
system process
|
GO:0003008 |
349 |
0.040
|
Human |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.040
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.040
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.040
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.040
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.039
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.039
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.039
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.038
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.038
|
Human |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.038
|
|
|
|
growth
|
GO:0040007 |
202 |
0.038
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.038
|
Fly |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.038
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.037
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.037
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.037
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.036
|
Fly |
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.036
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.036
|
|
|
|
isotype switching
|
GO:0045190 |
3 |
0.035
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.035
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.035
|
Human |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.035
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.035
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.035
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.034
|
Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.034
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.034
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.034
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.033
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.033
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.033
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.033
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.033
|
Human |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.033
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.032
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.032
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.032
|
Human |
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.032
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.032
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.032
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.032
|
Human |
|
|
immune response in mucosal associated lymphoid tissue
|
GO:0002386 |
1 |
0.032
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.031
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.031
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.030
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.030
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.030
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.030
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.030
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.030
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.030
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.030
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.030
|
Human |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.030
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.030
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.029
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.029
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.029
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.029
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.028
|
|
|
|
cell matrix adhesion involved in ameboidal cell migration
|
GO:0003366 |
2 |
0.028
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.028
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.028
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.028
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.028
|
|
|
|
receptor mediated virion attachment to host cell
|
GO:0046813 |
4 |
0.028
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.028
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.028
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.028
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.028
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.027
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.027
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.027
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.027
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.027
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.027
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.027
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.027
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.027
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.026
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.026
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.026
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.026
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.026
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.026
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.026
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.025
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.025
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.025
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.025
|
Fly |
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.025
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.025
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.025
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.025
|
Fly |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.025
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.024
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.024
|
Human |
|
|
positive regulation of cell killing
|
GO:0031343 |
19 |
0.024
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.024
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.024
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.024
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.024
|
Fly |
|
|
thiamine transmembrane transport
|
GO:0071934 |
2 |
0.024
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.023
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.023
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
18 |
0.023
|
|
|
|
memory
|
GO:0007613 |
3 |
0.023
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.023
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.023
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.023
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.023
|
|
|
|
azole transport
|
GO:0045117 |
4 |
0.023
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.023
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.023
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.023
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.023
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.023
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.023
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.022
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.022
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.022
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.022
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.022
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
Fly |
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.022
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.021
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.021
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.021
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.021
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.021
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
3 |
0.021
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.021
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.021
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.021
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.021
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.021
|
Human |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.021
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.020
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.020
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.020
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.020
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.020
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.020
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.020
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.020
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.020
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.019
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.019
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.019
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.019
|
|
|
|
regulation of cellular extravasation
|
GO:0002691 |
8 |
0.019
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.019
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.019
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.019
|
Human |
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.018
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.018
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.018
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.018
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.018
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.018
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.018
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.017
|
Human |
|
|
negative regulation of leukocyte mediated cytotoxicity
|
GO:0001911 |
5 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
Fly |
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.017
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.017
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.017
|
|
|
|
virion attachment to host cell
|
GO:0019062 |
5 |
0.017
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.017
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.017
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.017
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.017
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.017
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.017
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.017
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.017
|
|
|
|
positive t cell selection
|
GO:0043368 |
2 |
0.017
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.017
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.017
|
Fly |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.016
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.016
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.016
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.016
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.016
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.016
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.016
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.016
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.016
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.016
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.016
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.016
|
Human |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.016
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.016
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.016
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.016
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.016
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.016
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
19 |
0.016
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.015
|
Mouse |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.015
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.015
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.015
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.015
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.015
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.015
|
|
|
|
regulation of nk t cell activation
|
GO:0051133 |
4 |
0.015
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.015
|
|
