IMP

Process View

Homo sapiens

15 genes annotated in human

Multi-species View

negative regulation of anoikis

GO:2000811

Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of anoikis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of anoikis" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.999	Human
BCL2	B-cell CLL/lymphoma 2	0.996
FHL2	four and a half LIM domains 2	0.996
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.990
FYN	FYN oncogene related to SRC, FGR, YES	0.971	Human
BAX	BCL2-associated X protein	0.912	Human
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.911	Human
PSG9	pregnancy specific beta-1-glycoprotein 9	0.873	Human
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.835
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.813
FN1	fibronectin 1	0.808
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.803
BCL2L1	BCL2-like 1	0.791
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.778
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.654
SYK	spleen tyrosine kinase	0.651
PSG6	pregnancy specific beta-1-glycoprotein 6	0.597	Human
BID	BH3 interacting domain death agonist	0.538
PXN	paxillin	0.419
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.409
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.373
CAV1	caveolin 1, caveolae protein, 22kDa	0.350
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.330
PTK2	PTK2 protein tyrosine kinase 2	0.261
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.206
PSG4	pregnancy specific beta-1-glycoprotein 4	0.195
SFN	stratifin	0.183
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.182
LCK	lymphocyte-specific protein tyrosine kinase	0.181	Human
BAD	BCL2-associated agonist of cell death	0.159
ENG	endoglin	0.147
PTPRC	protein tyrosine phosphatase, receptor type, C	0.144
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.140
JAG1	jagged 1	0.136
PSG5	pregnancy specific beta-1-glycoprotein 5	0.123	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.120
PDIA3	protein disulfide isomerase family A, member 3	0.108
EPS8	epidermal growth factor receptor pathway substrate 8	0.098
SPRR2A	small proline-rich protein 2A	0.088
FLNA	filamin A, alpha	0.083
BAK1	BCL2-antagonist/killer 1	0.081	Human
PSG3	pregnancy specific beta-1-glycoprotein 3	0.080
IRS1	insulin receptor substrate 1	0.079
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.078
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.078	Human
ITGA6	integrin, alpha 6	0.077	Human
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.062	Human
FHL3	four and a half LIM domains 3	0.058
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.051
MYO10	myosin X	0.050
CYTH1	cytohesin 1	0.049
AR	androgen receptor	0.046
PLEC	plectin	0.043
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.043	Human
HCK	hemopoietic cell kinase	0.042	Human
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.040	Human
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.039
PSG1	pregnancy specific beta-1-glycoprotein 1	0.039
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.038
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.036	Human
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.034
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.032
DLL1	delta-like 1 (Drosophila)	0.032
MED28	mediator complex subunit 28	0.032
SH3KBP1	SH3-domain kinase binding protein 1	0.031
JUB	jub, ajuba homolog (Xenopus laevis)	0.030
EGFR	epidermal growth factor receptor	0.029
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.029
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.028	Human
NOTCH1	notch 1	0.027
MATK	megakaryocyte-associated tyrosine kinase	0.027
ICAM1	intercellular adhesion molecule 1	0.026
PTPRF	protein tyrosine phosphatase, receptor type, F	0.025
PDCD6IP	programmed cell death 6 interacting protein	0.025
WIPF1	WAS/WASL interacting protein family, member 1	0.022
ITGB5	integrin, beta 5	0.022	Human
ITGB4	integrin, beta 4	0.021	Human
CAV2	caveolin 2	0.020	Human
SRCIN1	SRC kinase signaling inhibitor 1	0.020
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.020
COL17A1	collagen, type XVII, alpha 1	0.019
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.019
NCK1	NCK adaptor protein 1	0.018
CLTC	clathrin, heavy chain (Hc)	0.018
PRKCB	protein kinase C, beta	0.017
CD22	CD22 molecule	0.017
ANGPTL4	angiopoietin-like 4	0.017
CMIP	c-Maf-inducing protein	0.017
PTEN	phosphatase and tensin homolog	0.017
CLEC4M	C-type lectin domain family 4, member M	0.017
TNS4	tensin 4	0.016
NTF4	neurotrophin 4	0.016
ANXA1	annexin A1	0.016
PSG7	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)	0.016
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.015
MUC1	mucin 1, cell surface associated	0.015
VCAM1	vascular cell adhesion molecule 1	0.015
CALD1	caldesmon 1	0.015
F2R	coagulation factor II (thrombin) receptor	0.014
GRB2	growth factor receptor-bound protein 2	0.014
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.014
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.014	Human
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.014
VAV1	vav 1 guanine nucleotide exchange factor	0.014
FAS	Fas (TNF receptor superfamily, member 6)	0.014
CTGF	connective tissue growth factor	0.014
PSEN2	presenilin 2 (Alzheimer disease 4)	0.013
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.013
NOTCH2NL	notch 2 N-terminal like	0.013
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.013
ALAS1	aminolevulinate, delta-, synthase 1	0.013
HPS6	Hermansky-Pudlak syndrome 6	0.013
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.013
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.012
RNF144B	ring finger protein 144B	0.012
NCF4	neutrophil cytosolic factor 4, 40kDa	0.012
GAS7	growth arrest-specific 7	0.012
PLAUR	plasminogen activator, urokinase receptor	0.011
TLN1	talin 1	0.011
PSG2	pregnancy specific beta-1-glycoprotein 2	0.011
TRAF3IP3	TRAF3 interacting protein 3	0.010