IMP

Process View

Homo sapiens

19 genes annotated in human

Multi-species View

regulation of t cell differentiation

GO:0045580

Any process that modulates the frequency, rate or extent of T cell differentiation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
LCK	lymphocyte-specific protein tyrosine kinase	0.780	Mouse
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.779
IL4R	interleukin 4 receptor	0.740	Mouse
B2M	beta-2-microglobulin	0.686
LAT	linker for activation of T cells	0.673
HLA-A	major histocompatibility complex, class I, A	0.552	Human
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.525
HLA-G	major histocompatibility complex, class I, G	0.512
EGFR	epidermal growth factor receptor	0.452
PLCG1	phospholipase C, gamma 1	0.333
HLA-F	major histocompatibility complex, class I, F	0.298	Human
HLA-E	major histocompatibility complex, class I, E	0.296	Human
CD80	CD80 molecule	0.275
HLA-B	major histocompatibility complex, class I, B	0.269
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.231
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.196	Human
HLA-DMB	major histocompatibility complex, class II, DM beta	0.195
HLA-C	major histocompatibility complex, class I, C	0.184	Human
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.179
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.172
CD247	CD247 molecule	0.159
PILRA	paired immunoglobin-like type 2 receptor alpha	0.143
BMPR1A	bone morphogenetic protein receptor, type IA	0.130
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.124
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.118
IL2RG	interleukin 2 receptor, gamma	0.109	Mouse
BIRC3	baculoviral IAP repeat containing 3	0.100
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.098
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.094
NCOR2	nuclear receptor corepressor 2	0.086
TAPBP	TAP binding protein (tapasin)	0.080
GRAP2	GRB2-related adaptor protein 2	0.059
TGIF1	TGFB-induced factor homeobox 1	0.059
VAV1	vav 1 guanine nucleotide exchange factor	0.058
CD86	CD86 molecule	0.056
IL2RB	interleukin 2 receptor, beta	0.055
CD22	CD22 molecule	0.055
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.054
TRAF1	TNF receptor-associated factor 1	0.051
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.051
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.049
IL15RA	interleukin 15 receptor, alpha	0.047
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.046	Human
NCOA1	nuclear receptor coactivator 1	0.046
LIN9	lin-9 homolog (C. elegans)	0.045
ICAM1	intercellular adhesion molecule 1	0.045
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.045	Human
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.042
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.040
JAK3	Janus kinase 3	0.040	Mouse
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.039
CTBP1	C-terminal binding protein 1	0.036
IL6R	interleukin 6 receptor	0.034
CXCR4	chemokine (C-X-C motif) receptor 4	0.034
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.033
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.032
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.032
FSTL1	follistatin-like 1	0.032
JAK1	Janus kinase 1	0.031
PPARA	peroxisome proliferator-activated receptor alpha	0.030
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.029
CCND3	cyclin D3	0.029
IL1R1	interleukin 1 receptor, type I	0.027
CCR7	chemokine (C-C motif) receptor 7	0.026
SMAD7	SMAD family member 7	0.026
EPOR	erythropoietin receptor	0.025
TGFB1	transforming growth factor, beta 1	0.024
BTN3A1	butyrophilin, subfamily 3, member A1	0.024
HDAC9	histone deacetylase 9	0.024
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.023
CDK6	cyclin-dependent kinase 6	0.023
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.023
TANK	TRAF family member-associated NFKB activator	0.023
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.022
IL4	interleukin 4	0.022
RXRA	retinoid X receptor, alpha	0.022
BTN3A3	butyrophilin, subfamily 3, member A3	0.022
PDPK1	3-phosphoinositide dependent protein kinase-1	0.022
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.021
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.021
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.020
CSK	c-src tyrosine kinase	0.020
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.020
SOCS3	suppressor of cytokine signaling 3	0.020
ESR1	estrogen receptor 1	0.020
NOD2	nucleotide-binding oligomerization domain containing 2	0.020
CCND1	cyclin D1	0.020
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.020
MED25	mediator complex subunit 25	0.019
EP300	E1A binding protein p300	0.019
PML	promyelocytic leukemia	0.019
SNX9	sorting nexin 9	0.018
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.018
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.018
DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	0.018
HCK	hemopoietic cell kinase	0.017
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.017
SH3BP2	SH3-domain binding protein 2	0.017
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.017
CD40	CD40 molecule, TNF receptor superfamily member 5	0.016
CHERP	calcium homeostasis endoplasmic reticulum protein	0.016
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.016
CCNE1	cyclin E1	0.016
CD33	CD33 molecule	0.016
JAK2	Janus kinase 2	0.016
IRF1	interferon regulatory factor 1	0.015	Mouse
NCK1	NCK adaptor protein 1	0.015
RBMX2	RNA binding motif protein, X-linked 2	0.015
CXCL3	chemokine (C-X-C motif) ligand 3	0.015
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.015
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.015
SOD2	superoxide dismutase 2, mitochondrial	0.015
RUNX1	runt-related transcription factor 1	0.014
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.014	Human
TGFB3	transforming growth factor, beta 3	0.014
BCL10	B-cell CLL/lymphoma 10	0.014
ITK	IL2-inducible T-cell kinase	0.014
TPP1	tripeptidyl peptidase I	0.014
FGFR1	fibroblast growth factor receptor 1	0.014
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.014
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.014
GBP1	guanylate binding protein 1, interferon-inducible	0.013
IL7R	interleukin 7 receptor	0.013	Mouse
GRB7	growth factor receptor-bound protein 7	0.013
BTN2A1	butyrophilin, subfamily 2, member A1	0.013	Mouse
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.013
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.013
ENG	endoglin	0.012
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.012
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.012
IL2RA	interleukin 2 receptor, alpha	0.012
CD6	CD6 molecule	0.012
CD320	CD320 molecule	0.012
PRKCQ	protein kinase C, theta	0.012
CD44	CD44 molecule (Indian blood group)	0.012
IL6	interleukin 6 (interferon, beta 2)	0.012	Mouse
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.012
PCDH9	protocadherin 9	0.012
TUBA1A	tubulin, alpha 1a	0.012
CD48	CD48 molecule	0.012
BTN3A2	butyrophilin, subfamily 3, member A2	0.012
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.012
INSR	insulin receptor	0.011
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.011
EGR2	early growth response 2	0.011
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.011
CD83	CD83 molecule	0.011	Mouse
CSNK1G1	casein kinase 1, gamma 1	0.011
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.011
HK3	hexokinase 3 (white cell)	0.011
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.011
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.011
IFNGR1	interferon gamma receptor 1	0.011
PLEK	pleckstrin	0.011
CD72	CD72 molecule	0.011
BTK	Bruton agammaglobulinemia tyrosine kinase	0.011
IL32	interleukin 32	0.011
HDAC5	histone deacetylase 5	0.010
IL10RA	interleukin 10 receptor, alpha	0.010
CCL20	chemokine (C-C motif) ligand 20	0.010
PRKD2	protein kinase D2	0.010
CCL4	chemokine (C-C motif) ligand 4	0.010
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.010
CD5	CD5 molecule	0.010
CD37	CD37 molecule	0.010
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.010
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.010
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.010
STAT5B	signal transducer and activator of transcription 5B	0.010	Mouse