Homo sapiens

72 known processes

MAPKAPK2

mitogen-activated protein kinase-activated protein kinase 2

(Aliases: MK2)

MAPKAPK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 247 0.934
response to biotic stimulus GO:0009607 276 0.884
Mouse
response to oxygen containing compound GO:1901700 369 0.797
Mouse
response to external biotic stimulus GO:0043207 261 0.775
Mouse
response to other organism GO:0051707 261 0.759
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.710
multicellular organismal aging GO:0010259 3 0.650
Worm
response to abiotic stimulus GO:0009628 336 0.636
Fly
tumor necrosis factor production GO:0032640 43 0.588
regulation of tumor necrosis factor production GO:0032680 43 0.570
defense response to fungus GO:0050832 4 0.489
regulation of protein serine threonine kinase activity GO:0071900 179 0.486
regulation of cytokine production GO:0001817 232 0.477
immune response GO:0006955 307 0.473
Mouse
embryonic placenta development GO:0001892 1 0.473
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.443
cellular response to endogenous stimulus GO:0071495 336 0.413
regulation of cell cycle GO:0051726 393 0.401
positive regulation of protein phosphorylation GO:0001934 313 0.400
response to bacterium GO:0009617 144 0.397
Mouse
regulation of kinase activity GO:0043549 314 0.390
protein autophosphorylation GO:0046777 123 0.373
Human
response to fungus GO:0009620 4 0.370
regulation of protein kinase activity GO:0045859 289 0.354
translation GO:0006412 132 0.349
Human
protein ubiquitination GO:0016567 314 0.347
cellular response to oxygen containing compound GO:1901701 276 0.346
single organism carbohydrate metabolic process GO:0044723 193 0.341
nervous system development GO:0007399 293 0.337
post embryonic development GO:0009791 2 0.323
mapk cascade GO:0000165 288 0.320
Fly
defense response to bacterium GO:0042742 63 0.317
peptidyl serine phosphorylation GO:0018105 101 0.314
erk1 and erk2 cascade GO:0070371 104 0.310
regulation of cellular amino acid metabolic process GO:0006521 6 0.299
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.298
nucleoside monophosphate metabolic process GO:0009123 191 0.296
regulation of defense response GO:0031347 154 0.286
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.280
negative regulation of catalytic activity GO:0043086 335 0.271
endomembrane system organization GO:0010256 196 0.262
negative regulation of intracellular signal transduction GO:1902532 183 0.259
positive regulation of developmental process GO:0051094 314 0.256
response to nitrogen compound GO:1901698 184 0.253
cell adhesion GO:0007155 325 0.241
Fly
carbohydrate metabolic process GO:0005975 207 0.225
negative regulation of lipid catabolic process GO:0050995 9 0.224
tor signaling GO:0031929 39 0.218
female gamete generation GO:0007292 2 0.214
signal transduction by phosphorylation GO:0023014 297 0.211
Fly
regulation of behavior GO:0050795 82 0.206
regulation of map kinase activity GO:0043405 108 0.204
peptidyl serine modification GO:0018209 106 0.203
defense response to gram negative bacterium GO:0050829 14 0.202
regulation of protein localization GO:0032880 296 0.197
biological adhesion GO:0022610 331 0.195
Fly
mrna 3 end processing GO:0031124 24 0.195
regulation of transferase activity GO:0051338 355 0.195
cellular response to growth factor stimulus GO:0071363 197 0.190
protein modification by small protein conjugation GO:0032446 342 0.189
ribonucleoside monophosphate catabolic process GO:0009158 158 0.187
defense response GO:0006952 315 0.185
Mouse
regulation of tor signaling GO:0032006 30 0.185
establishment of protein localization to organelle GO:0072594 172 0.184
defense response to other organism GO:0098542 129 0.183
determination of adult lifespan GO:0008340 2 0.181
Worm
regulation of erk1 and erk2 cascade GO:0070372 99 0.178
response to molecule of bacterial origin GO:0002237 82 0.178
Mouse
lipid metabolic process GO:0006629 381 0.177
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.169
positive regulation of immune system process GO:0002684 283 0.169
Mouse
purine ribonucleoside catabolic process GO:0046130 398 0.168
system process GO:0003008 349 0.164
positive regulation of vasoconstriction GO:0045907 3 0.163
negative regulation of apoptotic process GO:0043066 316 0.161
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.161
nuclear division GO:0000280 128 0.160
myoblast fusion GO:0007520 1 0.158
positive regulation of immune response GO:0050778 159 0.154
Mouse
cellular response to mechanical stimulus GO:0071260 39 0.154
cellular amine metabolic process GO:0044106 41 0.152
negative regulation of tor signaling GO:0032007 11 0.152
response to lipid GO:0033993 206 0.150
Mouse
mrna metabolic process GO:0016071 175 0.147
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.147
positive regulation of cellular amine metabolic process GO:0033240 7 0.146
positive regulation of cellular catabolic process GO:0031331 284 0.144
response to inorganic substance GO:0010035 127 0.143
vesicle mediated transport GO:0016192 371 0.143
Mouse
positive regulation of phosphorylation GO:0042327 394 0.141
actin filament organization GO:0007015 128 0.138
peptidyl threonine modification GO:0018210 45 0.134
positive regulation of defense response GO:0031349 87 0.134
Mouse
negative regulation of cytokine production GO:0001818 82 0.133
response to growth factor GO:0070848 205 0.132
negative regulation of protein phosphorylation GO:0001933 140 0.129
regulation of cell cycle process GO:0010564 266 0.129
cellular macromolecule catabolic process GO:0044265 380 0.129
protein targeting GO:0006605 187 0.128
intracellular protein transport GO:0006886 270 0.128
anatomical structure formation involved in morphogenesis GO:0048646 284 0.127
organelle fission GO:0048285 149 0.127
enzyme linked receptor protein signaling pathway GO:0007167 303 0.125
positive regulation of intracellular protein transport GO:0090316 76 0.123
mrna processing GO:0006397 133 0.122
regulation of translation GO:0006417 89 0.122
Human
glycosyl compound catabolic process GO:1901658 413 0.122
syncytium formation by plasma membrane fusion GO:0000768 2 0.121
oogenesis GO:0048477 2 0.119
posttranscriptional regulation of gene expression GO:0010608 213 0.119
innate immune response GO:0045087 178 0.119
Mouse
positive regulation of actin filament bundle assembly GO:0032233 25 0.119
establishment of planar polarity GO:0001736 3 0.115
positive regulation of cell size GO:0045793 3 0.113
Fly
regulation of mapk cascade GO:0043408 262 0.112
Fly
positive regulation of cell proliferation GO:0008284 301 0.109
regeneration GO:0031099 4 0.106
compound eye development GO:0048749 1 0.106
extrinsic apoptotic signaling pathway GO:0097191 119 0.106
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.105
regulation of cell migration GO:0030334 289 0.105
cellular response to molecule of bacterial origin GO:0071219 62 0.105
cellular lipid metabolic process GO:0044255 303 0.104
monosaccharide metabolic process GO:0005996 74 0.103
regulation of innate immune response GO:0045088 97 0.102
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.101
aging GO:0007568 66 0.101
Human Worm
cellular response to hormone stimulus GO:0032870 125 0.100
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.100
regulation of cell motility GO:2000145 299 0.100
actin filament based process GO:0030029 224 0.099
peptidyl threonine phosphorylation GO:0018107 41 0.098
cellular response to nitrogen compound GO:1901699 144 0.098
single organism cellular localization GO:1902580 332 0.098
innate immune response activating signal transduction GO:0002758 48 0.097
Mouse
response to extracellular stimulus GO:0009991 85 0.097
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.097
positive regulation of map kinase activity GO:0043406 80 0.097
regulation of response to external stimulus GO:0032101 222 0.095
negative regulation of cellular protein metabolic process GO:0032269 353 0.095
purine ribonucleoside metabolic process GO:0046128 437 0.094
muscle structure development GO:0061061 98 0.094
negative regulation of phosphorylation GO:0042326 174 0.094
purine nucleoside triphosphate catabolic process GO:0009146 392 0.094
reactive nitrogen species metabolic process GO:2001057 3 0.093
positive regulation of catabolic process GO:0009896 310 0.093
ras protein signal transduction GO:0007265 73 0.093
Human
growth GO:0040007 202 0.092
positive regulation of behavior GO:0048520 60 0.092
purine nucleoside monophosphate metabolic process GO:0009126 186 0.092
regulation of protein transport GO:0051223 213 0.091
nucleoside monophosphate catabolic process GO:0009125 159 0.091
positive regulation of myotube differentiation GO:0010831 3 0.090
regulation of small gtpase mediated signal transduction GO:0051056 156 0.090
cellular response to dna damage stimulus GO:0006974 379 0.089
positive regulation of transferase activity GO:0051347 227 0.089
regulation of apoptotic signaling pathway GO:2001233 175 0.089
negative regulation of cell proliferation GO:0008285 228 0.088
positive regulation of cell differentiation GO:0045597 211 0.087
response to oxidative stress GO:0006979 121 0.086
response to organonitrogen compound GO:0010243 156 0.086
protein localization to membrane GO:0072657 160 0.085
positive regulation of superoxide anion generation GO:0032930 4 0.085
chordate embryonic development GO:0043009 34 0.084
response to endoplasmic reticulum stress GO:0034976 49 0.084
ribonucleoside catabolic process GO:0042454 406 0.083
cell junction organization GO:0034330 79 0.082
response to reactive oxygen species GO:0000302 61 0.082
small gtpase mediated signal transduction GO:0007264 78 0.082
Human
positive regulation of cellular component organization GO:0051130 376 0.082
purine ribonucleotide catabolic process GO:0009154 404 0.081
peripheral nervous system development GO:0007422 2 0.081
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.081
mating GO:0007618 1 0.081
cell development GO:0048468 328 0.080
activation of mapk activity GO:0000187 45 0.080
regulation of intracellular transport GO:0032386 195 0.080
positive regulation of protein kinase activity GO:0045860 190 0.079
regulation of nucleoside metabolic process GO:0009118 209 0.078
regulation of binding GO:0051098 111 0.078
response to salt stress GO:0009651 3 0.078
Fly
response to uv GO:0009411 73 0.078
positive regulation of mapk cascade GO:0043410 190 0.078
positive regulation of glial cell proliferation GO:0060252 2 0.077
negative regulation of tumor necrosis factor production GO:0032720 20 0.076
epithelium development GO:0060429 227 0.076
Zebrafish
response to hormone GO:0009725 175 0.075
response to radiation GO:0009314 151 0.075
negative regulation of phosphorus metabolic process GO:0010563 267 0.075
nucleoside catabolic process GO:0009164 408 0.074
regulation of immune response GO:0050776 201 0.073
Mouse
single organism reproductive process GO:0044702 98 0.071
negative regulation of phosphate metabolic process GO:0045936 267 0.071
neurogenesis GO:0022008 169 0.071
blood vessel endothelial cell migration GO:0043534 42 0.071
regulation of establishment of protein localization GO:0070201 242 0.070
cellular ketone metabolic process GO:0042180 80 0.070
regulation of cytokine biosynthetic process GO:0042035 35 0.069
purine nucleoside monophosphate catabolic process GO:0009128 158 0.069
transmission of nerve impulse GO:0019226 11 0.067
nuclear import GO:0051170 106 0.067
positive regulation of transport GO:0051050 336 0.067
reproductive process GO:0022414 106 0.067
positive regulation of hydrolase activity GO:0051345 331 0.067
lipid localization GO:0010876 106 0.067
i kappab kinase nf kappab signaling GO:0007249 166 0.066
circadian behavior GO:0048512 2 0.066
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.066
nucleocytoplasmic transport GO:0006913 176 0.065
positive regulation of cell migration GO:0030335 172 0.064
mitochondrion organization GO:0007005 156 0.064
phospholipid catabolic process GO:0009395 12 0.064
response to metal ion GO:0010038 84 0.064
multicellular organismal reproductive process GO:0048609 40 0.063
leukocyte differentiation GO:0002521 98 0.063
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.062
positive regulation of gliogenesis GO:0014015 4 0.062
lipid modification GO:0030258 84 0.061
organonitrogen compound biosynthetic process GO:1901566 200 0.061
modification dependent protein catabolic process GO:0019941 209 0.061
cellular response to abiotic stimulus GO:0071214 117 0.061
regulation of membrane potential GO:0042391 95 0.060
protein localization to nucleus GO:0034504 136 0.060
positive regulation of kinase activity GO:0033674 204 0.059
regulation of glucosylceramide catabolic process GO:2000752 1 0.059
dephosphorylation GO:0016311 209 0.059
regulation of striated muscle cell differentiation GO:0051153 25 0.058
positive regulation of muscle cell differentiation GO:0051149 15 0.058
cytokine biosynthetic process GO:0042089 37 0.058
cardiac muscle tissue development GO:0048738 39 0.057
protein targeting to nucleus GO:0044744 104 0.057
regulation of growth GO:0040008 165 0.056
neuromuscular junction development GO:0007528 3 0.056
chromatin modification GO:0016568 298 0.056
neuronal action potential GO:0019228 9 0.056
atp metabolic process GO:0046034 176 0.056
positive regulation of cell motility GO:2000147 177 0.056
activation of immune response GO:0002253 114 0.055
Mouse
regulation of anatomical structure size GO:0090066 101 0.054
Fly
actin cytoskeleton organization GO:0030036 207 0.054
response to heat GO:0009408 21 0.054
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.054
negative regulation of tumor necrosis factor superfamily cytokine production GO:1903556 20 0.053
rna catabolic process GO:0006401 71 0.053
negative regulation of transferase activity GO:0051348 124 0.052
nucleoside triphosphate metabolic process GO:0009141 422 0.052
cell activation GO:0001775 213 0.052
reactive oxygen species biosynthetic process GO:1903409 4 0.052
lymphocyte activation GO:0046649 133 0.052
protein localization to plasma membrane GO:0072659 93 0.052
positive regulation of cell development GO:0010720 92 0.051
positive regulation of organelle organization GO:0010638 195 0.051
regulation of cellular ketone metabolic process GO:0010565 50 0.051
reproduction GO:0000003 63 0.051
positive regulation of protein transport GO:0051222 135 0.051
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.050
regulation of ras gtpase activity GO:0032318 128 0.049
positive regulation of glucosylceramide catabolic process GO:2000753 1 0.049
regulation of mrna catabolic process GO:0061013 13 0.049
regulation of peptidase activity GO:0052547 180 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.049
purine nucleotide catabolic process GO:0006195 405 0.049
cytoplasmic mrna processing body assembly GO:0033962 10 0.049
regulation of cellular response to stress GO:0080135 244 0.049
Fly
cell aging GO:0007569 52 0.049
Human
p38mapk cascade GO:0038066 9 0.049
regulation of system process GO:0044057 101 0.049
immune system development GO:0002520 195 0.049
carbohydrate biosynthetic process GO:0016051 42 0.048
single organism cell adhesion GO:0098602 179 0.048
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.047
membrane organization GO:0061024 292 0.047
oxidation reduction process GO:0055114 396 0.047
single organism nuclear import GO:1902593 104 0.046
protein catabolic process GO:0030163 325 0.046
negative regulation of t cell apoptotic process GO:0070233 4 0.046
polysaccharide biosynthetic process GO:0000271 27 0.046
stress fiber assembly GO:0043149 40 0.045
reproductive system development GO:0061458 56 0.045
endocytosis GO:0006897 159 0.044
Mouse
negative regulation of catabolic process GO:0009895 104 0.044
mitotic cell cycle GO:0000278 326 0.044
positive regulation of cell activation GO:0050867 81 0.043
reproductive structure development GO:0048608 55 0.043
mucopolysaccharide metabolic process GO:1903510 27 0.043
response to uv a GO:0070141 6 0.043
oocyte differentiation GO:0009994 2 0.042
apoptotic signaling pathway GO:0097190 268 0.042
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.042
negative regulation of glial cell apoptotic process GO:0034351 6 0.042
regulation of carbohydrate metabolic process GO:0006109 54 0.041
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.041
embryo development GO:0009790 123 0.041
Zebrafish
positive regulation of myoblast fusion GO:1901741 1 0.041
response to topologically incorrect protein GO:0035966 29 0.041
regulation of protein targeting GO:1903533 91 0.041
striated muscle cell differentiation GO:0051146 43 0.041
nuclear transport GO:0051169 179 0.041
multicellular organism reproduction GO:0032504 42 0.040
negative regulation of cell death GO:0060548 345 0.040
regulation of intracellular protein transport GO:0033157 123 0.040
cellular component morphogenesis GO:0032989 314 0.040
Fly
regulation of gtpase activity GO:0043087 180 0.040
organophosphate catabolic process GO:0046434 430 0.040
regulation of protein catabolic process GO:0042176 155 0.039
cytoplasmic transport GO:0016482 379 0.039
response to nitrosative stress GO:0051409 4 0.039
protein localization to organelle GO:0033365 280 0.039
cellular response to biotic stimulus GO:0071216 71 0.039
t cell activation GO:0042110 99 0.039
apoptotic mitochondrial changes GO:0008637 57 0.039
glial cell migration GO:0008347 4 0.039
protein maturation GO:0051604 233 0.039
cellular response to reactive oxygen species GO:0034614 50 0.038
regulation of reactive oxygen species metabolic process GO:2000377 41 0.038
regulation of locomotion GO:0040012 329 0.038
osteoblast differentiation GO:0001649 92 0.038
covalent chromatin modification GO:0016569 254 0.038
establishment of tissue polarity GO:0007164 3 0.038
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.038
viral process GO:0016032 146 0.038
positive regulation of cell growth GO:0030307 48 0.038
activation of innate immune response GO:0002218 55 0.037
Mouse
nuclear transcribed mrna catabolic process GO:0000956 48 0.037
regulation of ubiquitin protein transferase activity GO:0051438 28 0.037
negative regulation of protein modification process GO:0031400 200 0.037
protein import into nucleus GO:0006606 104 0.037
response to wounding GO:0009611 168 0.037
developmental process involved in reproduction GO:0003006 66 0.037
cell cycle checkpoint GO:0000075 117 0.037
generation of neurons GO:0048699 152 0.037
positive regulation of growth GO:0045927 58 0.037
rna 3 end processing GO:0031123 35 0.036
regulation of cell differentiation GO:0045595 393 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
cell morphogenesis GO:0000902 296 0.036
Fly
cell aggregation GO:0098743 1 0.036
membrane lipid metabolic process GO:0006643 53 0.036
spindle checkpoint GO:0031577 26 0.036
ossification GO:0001503 121 0.036
positive regulation of cell cycle GO:0045787 140 0.036
cytokine metabolic process GO:0042107 38 0.036
cellular response to external stimulus GO:0071496 111 0.036
ribonucleotide catabolic process GO:0009261 405 0.036
establishment of protein localization to plasma membrane GO:0090002 68 0.036
spermatid differentiation GO:0048515 4 0.036
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.036
regulation of protein ubiquitination GO:0031396 95 0.036
positive regulation of fat cell differentiation GO:0045600 12 0.036
regulation of mrna metabolic process GO:1903311 53 0.036
regulation of actin cytoskeleton organization GO:0032956 116 0.036
purine containing compound catabolic process GO:0072523 411 0.036
glucosylceramide metabolic process GO:0006678 3 0.035
regulation of myoblast fusion GO:1901739 1 0.035
positive regulation of neuron projection development GO:0010976 34 0.035
neuron projection morphogenesis GO:0048812 50 0.035
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 2 0.035
chemical homeostasis GO:0048878 306 0.034
negative regulation of mapk cascade GO:0043409 56 0.034
leukocyte activation GO:0045321 164 0.034
ribonucleoside monophosphate metabolic process GO:0009161 187 0.034
response to light stimulus GO:0009416 87 0.034
peptidyl tyrosine modification GO:0018212 170 0.034
response to hydrogen peroxide GO:0042542 40 0.034
peroxisome degradation GO:0030242 1 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.034
positive regulation of binding GO:0051099 45 0.034
positive regulation of cell projection organization GO:0031346 64 0.034
neuron development GO:0048666 113 0.033
regulation of muscle hypertrophy GO:0014743 10 0.033
locomotory behavior GO:0007626 1 0.033
negative regulation of developmental process GO:0051093 247 0.033
gonad development GO:0008406 34 0.033
immune effector process GO:0002252 159 0.033
placenta development GO:0001890 10 0.033
regulation of cellular component size GO:0032535 82 0.033
Fly
heart development GO:0007507 95 0.033
response to cytokine GO:0034097 232 0.033
regulation of polysaccharide biosynthetic process GO:0032885 20 0.032
fatty acid metabolic process GO:0006631 115 0.032
neuron projection regeneration GO:0031102 1 0.032
negative regulation of erk1 and erk2 cascade GO:0070373 14 0.032
response to mechanical stimulus GO:0009612 51 0.032
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.032
liposaccharide metabolic process GO:1903509 27 0.032
positive regulation of gtpase activity GO:0043547 166 0.032
rna processing GO:0006396 255 0.032
mitotic cell cycle phase transition GO:0044772 162 0.031
regulation of chemotaxis GO:0050920 74 0.031
regulation of dna metabolic process GO:0051052 153 0.031
positive regulation of ras gtpase activity GO:0032320 117 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
regulation of protein localization to nucleus GO:1900180 85 0.031
positive regulation of stress fiber assembly GO:0051496 22 0.031
activation induced cell death of t cells GO:0006924 2 0.031
negative regulation of protein kinase activity GO:0006469 98 0.031
cellular response to organic cyclic compound GO:0071407 127 0.030
positive regulation of axon extension GO:0045773 4 0.030
stress activated protein kinase signaling cascade GO:0031098 94 0.030
Fly
negative regulation of protein catabolic process GO:0042177 59 0.030
alcohol metabolic process GO:0006066 114 0.030
myeloid leukocyte differentiation GO:0002573 60 0.030
regulation of dna binding GO:0051101 37 0.030
nucleotide catabolic process GO:0009166 408 0.030
activation of protein kinase activity GO:0032147 90 0.029
organelle assembly GO:0070925 176 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.029
receptor mediated endocytosis GO:0006898 84 0.029
morphogenesis of embryonic epithelium GO:0016331 4 0.029
striated muscle myosin thick filament assembly GO:0071688 2 0.029
single organism membrane organization GO:0044802 268 0.029
meiotic nuclear division GO:0007126 10 0.029
glucose metabolic process GO:0006006 45 0.029
response to nutrient levels GO:0031667 81 0.029
defense response to gram positive bacterium GO:0050830 29 0.029
tissue regeneration GO:0042246 3 0.029
positive regulation of apoptotic process GO:0043065 246 0.028
morphogenesis of a polarized epithelium GO:0001738 3 0.028
regulation of cellular protein catabolic process GO:1903362 96 0.028
multi organism reproductive process GO:0044703 54 0.028
spermatid development GO:0007286 4 0.028
hemopoiesis GO:0030097 180 0.028
atp catabolic process GO:0006200 157 0.028
neuron differentiation GO:0030182 138 0.028
negative regulation of response to external stimulus GO:0032102 83 0.028
dna repair GO:0006281 198 0.028
regulation of multi organism process GO:0043900 157 0.027
response to lipopolysaccharide GO:0032496 70 0.027
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.027
circulatory system process GO:0003013 113 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.027
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
cardiovascular system development GO:0072358 262 0.027
establishment of protein localization to membrane GO:0090150 121 0.027
developmental growth GO:0048589 48 0.027
t cell homeostasis GO:0043029 3 0.027
regulation of stress fiber assembly GO:0051492 32 0.027
regulation of cell projection organization GO:0031344 107 0.027
regulation of neuron differentiation GO:0045664 70 0.027
cellular polysaccharide biosynthetic process GO:0033692 21 0.026
cellular response to lipopolysaccharide GO:0071222 57 0.026
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.026
immune response regulating signaling pathway GO:0002764 97 0.026
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.026
jun phosphorylation GO:0007258 28 0.026
endochondral bone morphogenesis GO:0060350 3 0.026
regulation of plasma lipoprotein particle levels GO:0097006 32 0.026
anatomical structure homeostasis GO:0060249 100 0.026
wnt signaling pathway GO:0016055 156 0.026
response to axon injury GO:0048678 1 0.026
positive regulation of neuron differentiation GO:0045666 40 0.026
regulation of response to wounding GO:1903034 101 0.026
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.025
organic hydroxy compound metabolic process GO:1901615 147 0.025
mitotic cell cycle process GO:1903047 286 0.025
termination of signal transduction GO:0023021 3 0.025
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.025
regulation of sphingomyelin catabolic process GO:2000754 1 0.025
t cell differentiation in thymus GO:0033077 4 0.025
blood vessel morphogenesis GO:0048514 162 0.025
stress activated mapk cascade GO:0051403 93 0.025
Fly
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.025
regulation of actin filament based process GO:0032970 141 0.025
multicellular organismal signaling GO:0035637 34 0.025
protein processing GO:0016485 226 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
glycolipid metabolic process GO:0006664 27 0.025
negative regulation of apoptotic signaling pathway GO:2001234 97 0.024
regulation of cell junction assembly GO:1901888 29 0.024
lipid biosynthetic process GO:0008610 177 0.024
hexose metabolic process GO:0019318 55 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
muscle system process GO:0003012 81 0.024
t helper 2 cell differentiation GO:0045064 1 0.024
cell cell junction organization GO:0045216 69 0.024

MAPKAPK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 38 0.111
nervous system disease DOID:863 431 0.111
neuropathy DOID:870 52 0.111
immune system disease DOID:2914 155 0.106
muscular disease DOID:0080000 114 0.100
musculoskeletal system disease DOID:17 223 0.100
muscle tissue disease DOID:66 113 0.100
central nervous system disease DOID:331 186 0.074
neurodegenerative disease DOID:1289 102 0.074
myopathy DOID:423 104 0.060
charcot marie tooth disease type 2 DOID:0050539 15 0.048
charcot marie tooth disease DOID:10595 33 0.048
heart disease DOID:114 68 0.045
cardiomyopathy DOID:0050700 50 0.045
cardiovascular system disease DOID:1287 106 0.045
kidney disease DOID:557 36 0.035
urinary system disease DOID:18 40 0.035
cancer DOID:162 167 0.031
disease of cellular proliferation DOID:14566 174 0.031
organ system cancer DOID:0050686 164 0.031