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Homo sapiens

30 genes annotated in human

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regulation of tor signaling

GO:0032006

Any process that modulates the frequency, rate or extent of TOR signaling.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of tor signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of tor signaling" (in gray)

Name	Description	Probability	Func Analog Organism
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	1.000
RPTOR	regulatory associated protein of MTOR, complex 1	1.000
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	1.000
RRAGC	Ras-related GTP binding C	0.999
RICTOR	RPTOR independent companion of MTOR, complex 2	0.998
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.996
TELO2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.996
SKP1	S-phase kinase-associated protein 1	0.994
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.989
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.985	Human
BTRC	beta-transducin repeat containing	0.976	Fly
FBXW11	F-box and WD repeat domain containing 11	0.965	Fly
SOS1	son of sevenless homolog 1 (Drosophila)	0.947
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.919
RHEB	Ras homolog enriched in brain	0.912
DEPTOR	DEP domain containing MTOR-interacting protein	0.906
LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.905
PRR5	proline rich 5 (renal)	0.878
AXL	AXL receptor tyrosine kinase	0.865
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.856
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.849
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.832	Human
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.826
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.825
EGFR	epidermal growth factor receptor	0.806
AKT1S1	AKT1 substrate 1 (proline-rich)	0.793
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.758
RRAGD	Ras-related GTP binding D	0.752
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.680
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.569
CDK17	cyclin-dependent kinase 17	0.462
IRS1	insulin receptor substrate 1	0.436
C7orf59	chromosome 7 open reading frame 59	0.434
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.388
FKBP1A	FK506 binding protein 1A, 12kDa	0.366
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.360
IRS2	insulin receptor substrate 2	0.352
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	0.352
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.348
MAP2K1	mitogen-activated protein kinase kinase 1	0.343
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.343
TTI1	Tel2 interacting protein 1 homolog (S. pombe)	0.340
LAT	linker for activation of T cells	0.293
CLOCK	clock homolog (mouse)	0.265
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.257
HBXIP	hepatitis B virus x interacting protein	0.251
RRAGA	Ras-related GTP binding A	0.247	Human Worm
GRB2	growth factor receptor-bound protein 2	0.239
YAP1	Yes-associated protein 1	0.238
TRAF2	TNF receptor-associated factor 2	0.231
HDAC4	histone deacetylase 4	0.211
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.201
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.190
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.185
FBXW2	F-box and WD repeat domain containing 2	0.179
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.177
GSK3B	glycogen synthase kinase 3 beta	0.173
NCF4	neutrophil cytosolic factor 4, 40kDa	0.171
DAPK1	death-associated protein kinase 1	0.147
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.144
TFRC	transferrin receptor (p90, CD71)	0.137
RHEBL1	Ras homolog enriched in brain like 1	0.121	Human Fly
ABI1	abl-interactor 1	0.114
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.111
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.103
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.099
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.096
GHR	growth hormone receptor	0.093
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.093
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.093
RANBP9	RAN binding protein 9	0.090
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.087
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.086
MARK3	MAP/microtubule affinity-regulating kinase 3	0.086
EPOR	erythropoietin receptor	0.084
C7orf25	chromosome 7 open reading frame 25	0.081
PLEC	plectin	0.070
PEF1	penta-EF-hand domain containing 1	0.068
VEGFA	vascular endothelial growth factor A	0.067
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.063
EGLN1	egl nine homolog 1 (C. elegans)	0.063
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.062
IREB2	iron-responsive element binding protein 2	0.061
LARS	leucyl-tRNA synthetase	0.060	Yeast
KAT2B	K(lysine) acetyltransferase 2B	0.060
GRB10	growth factor receptor-bound protein 10	0.058
MTA1	metastasis associated 1	0.058
CUL1	cullin 1	0.057	Fly
DDB1	damage-specific DNA binding protein 1, 127kDa	0.057
DLG1	discs, large homolog 1 (Drosophila)	0.056
SCYL2	SCY1-like 2 (S. cerevisiae)	0.054
WEE1	WEE1 homolog (S. pombe)	0.054
RAB2A	RAB2A, member RAS oncogene family	0.054
PDCD6IP	programmed cell death 6 interacting protein	0.053
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.052	Mouse
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.052
TXNL4A	thioredoxin-like 4A	0.051
MAPK1	mitogen-activated protein kinase 1	0.051
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	0.049
TSG101	tumor susceptibility gene 101	0.048
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.048
PRR5L	proline rich 5 like	0.047
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.046
TSC2	tuberous sclerosis 2	0.044	Mouse Rat Fly
AXIN1	axin 1	0.044
JAK2	Janus kinase 2	0.044
BECN1	beclin 1, autophagy related	0.043
PRKCE	protein kinase C, epsilon	0.042
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.042
FKBP8	FK506 binding protein 8, 38kDa	0.042
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.042
C8orf41	chromosome 8 open reading frame 41	0.041
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.041
RABIF	RAB interacting factor	0.040
SH3RF1	SH3 domain containing ring finger 1	0.039
KSR1	kinase suppressor of ras 1	0.038	Human
KIF1B	kinesin family member 1B	0.038
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.038
DENND4A	DENN/MADD domain containing 4A	0.038
TRIM9	tripartite motif containing 9	0.037
SIRT1	sirtuin 1	0.036
BCAR1	breast cancer anti-estrogen resistance 1	0.035
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.035
BIRC6	baculoviral IAP repeat containing 6	0.034
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.033
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.032
SOS2	son of sevenless homolog 2 (Drosophila)	0.032
STAT5A	signal transducer and activator of transcription 5A	0.032
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.032
PDPK1	3-phosphoinositide dependent protein kinase-1	0.032
EPAS1	endothelial PAS domain protein 1	0.032
LYSMD3	LysM, putative peptidoglycan-binding, domain containing 3	0.031
ARHGAP5	Rho GTPase activating protein 5	0.030
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.030
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.030
TH1L	TH1-like (Drosophila)	0.029
MPRIP	myosin phosphatase Rho interacting protein	0.028
CCDC6	coiled-coil domain containing 6	0.028
FBXO33	F-box protein 33	0.028
FOXO3	forkhead box O3	0.028
GAB1	GRB2-associated binding protein 1	0.027
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.027
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.027
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.026
STK38	serine/threonine kinase 38	0.026
MARK2	MAP/microtubule affinity-regulating kinase 2	0.026
EGLN3	egl nine homolog 3 (C. elegans)	0.025
SLK	STE20-like kinase	0.025
FBXO3	F-box protein 3	0.024
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.024	Fly
HEBP2	heme binding protein 2	0.024
BAG1	BCL2-associated athanogene	0.024
ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	0.023
MBNL2	muscleblind-like 2 (Drosophila)	0.023
MAP2K2	mitogen-activated protein kinase kinase 2	0.023
MAF1	MAF1 homolog (S. cerevisiae)	0.023
FNIP1	folliculin interacting protein 1	0.023
KIAA0930	KIAA0930	0.022
FAM82A2	family with sequence similarity 82, member A2	0.022
MAPK3	mitogen-activated protein kinase 3	0.022
AHR	aryl hydrocarbon receptor	0.022
TXNIP	thioredoxin interacting protein	0.021
ARL15	ADP-ribosylation factor-like 15	0.021
SOCS5	suppressor of cytokine signaling 5	0.021
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.021
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.020
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.020
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.020	Mouse
TBK1	TANK-binding kinase 1	0.020
DCTN4	dynactin 4 (p62)	0.020
FEM1B	fem-1 homolog b (C. elegans)	0.020
FEM1C	fem-1 homolog c (C. elegans)	0.020
RIOK3	RIO kinase 3 (yeast)	0.019
ARHGAP12	Rho GTPase activating protein 12	0.019
NCF1	neutrophil cytosolic factor 1	0.019
GAB2	GRB2-associated binding protein 2	0.019
ACVR1	activin A receptor, type I	0.019
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.019
RASAL2	RAS protein activator like 2	0.018
SH3GL2	SH3-domain GRB2-like 2	0.018
RAP1A	RAP1A, member of RAS oncogene family	0.018
ZNF295	zinc finger protein 295	0.018
HSPA1B	heat shock 70kDa protein 1B	0.018
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.018
TIAM1	T-cell lymphoma invasion and metastasis 1	0.018
ANXA11	annexin A11	0.018
UBXN7	UBX domain protein 7	0.018
RAD18	RAD18 homolog (S. cerevisiae)	0.017
TJP2	tight junction protein 2 (zona occludens 2)	0.017
CUL4A	cullin 4A	0.017
CXCR5	chemokine (C-X-C motif) receptor 5	0.017
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.017
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.017
LARP1	La ribonucleoprotein domain family, member 1	0.017
CAPN7	calpain 7	0.017
KIF1C	kinesin family member 1C	0.017
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.016
RRAGB	Ras-related GTP binding B	0.016
PRKCA	protein kinase C, alpha	0.016
PEBP1	phosphatidylethanolamine binding protein 1	0.016
PPTC7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.016
EEF2K	eukaryotic elongation factor-2 kinase	0.016
PNPLA8	patatin-like phospholipase domain containing 8	0.016
SEC24B	SEC24 family, member B (S. cerevisiae)	0.015
SPAG9	sperm associated antigen 9	0.015
CMIP	c-Maf-inducing protein	0.015
PIK3C3	phosphoinositide-3-kinase, class 3	0.015
OSBPL3	oxysterol binding protein-like 3	0.015
RAI14	retinoic acid induced 14	0.015
RGS19	regulator of G-protein signaling 19	0.015
FBXW7	F-box and WD repeat domain containing 7	0.014
YY1	YY1 transcription factor	0.014
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.014
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.014
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.014	Human
ACACA	acetyl-CoA carboxylase alpha	0.014
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.014
HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1	0.014
CHMP4B	chromatin modifying protein 4B	0.013
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.013
CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	0.013
CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	0.013
STAT5B	signal transducer and activator of transcription 5B	0.013
MAP2K5	mitogen-activated protein kinase kinase 5	0.013
PRPF39	PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae)	0.013
UBR2	ubiquitin protein ligase E3 component n-recognin 2	0.013
PCGF5	polycomb group ring finger 5	0.013
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.013
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
USP24	ubiquitin specific peptidase 24	0.013
RDX	radixin	0.012
RAB21	RAB21, member RAS oncogene family	0.012
RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	0.012
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.012
BCR	breakpoint cluster region	0.012
TM2D3	TM2 domain containing 3	0.012
C16orf80	chromosome 16 open reading frame 80	0.012
CTTN	cortactin	0.012
PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2	0.012
SPRY2	sprouty homolog 2 (Drosophila)	0.012
DDX55	DEAD (Asp-Glu-Ala-Asp) box polypeptide 55	0.012
NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	0.012
CSNK1G3	casein kinase 1, gamma 3	0.012
TYK2	tyrosine kinase 2	0.012
AXIN2	axin 2	0.011
TRIM23	tripartite motif containing 23	0.011
LIMK1	LIM domain kinase 1	0.011
PICALM	phosphatidylinositol binding clathrin assembly protein	0.011
PTK2	PTK2 protein tyrosine kinase 2	0.011
ASS1	argininosuccinate synthase 1	0.011
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.011
NFIL3	nuclear factor, interleukin 3 regulated	0.011
SLAIN2	SLAIN motif family, member 2	0.011
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.011
ZRANB1	zinc finger, RAN-binding domain containing 1	0.011
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.011
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.011
KLC1	kinesin light chain 1	0.011
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.011
CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1	0.011
FBXO4	F-box protein 4	0.011
CCNY	cyclin Y	0.011
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.011
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.011
MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	0.011
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.011
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.011
SMAD7	SMAD family member 7	0.010
C10orf26	chromosome 10 open reading frame 26	0.010
SSFA2	sperm specific antigen 2	0.010
EIF1	eukaryotic translation initiation factor 1	0.010
VPS4B	vacuolar protein sorting 4 homolog B (S. cerevisiae)	0.010
ZBTB37	zinc finger and BTB domain containing 37	0.010
IGF1R	insulin-like growth factor 1 receptor	0.010	Human
RAB9A	RAB9A, member RAS oncogene family	0.010
FLOT2	flotillin 2	0.010
PRKCB	protein kinase C, beta	0.010
MORC3	MORC family CW-type zinc finger 3	0.010
FNBP1L	formin binding protein 1-like	0.010
PTPRS	protein tyrosine phosphatase, receptor type, S	0.010
SPSB2	splA/ryanodine receptor domain and SOCS box containing 2	0.010