IMP

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Homo sapiens

29 genes annotated in human

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regulation of cell junction assembly

GO:1901888

Any process that modulates the frequency, rate or extent of cell junction assembly.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell junction assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cell junction assembly" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.999	Human
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.989	Human
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.970
BCAR1	breast cancer anti-estrogen resistance 1	0.946
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.928	Human
VEGFA	vascular endothelial growth factor A	0.896
PTK2	PTK2 protein tyrosine kinase 2	0.889
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.785
RHOA	ras homolog gene family, member A	0.692
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.663
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.622	Human
NRP1	neuropilin 1	0.615
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.602
S100A1	S100 calcium binding protein A1	0.593	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.582	Human
S100B	S100 calcium binding protein B	0.569	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.501	Human
SMAD2	SMAD family member 2	0.467
FYN	FYN oncogene related to SRC, FGR, YES	0.428
EGFR	epidermal growth factor receptor	0.360
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.351	Human
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.347
CDH5	cadherin 5, type 2 (vascular endothelium)	0.297
NCK2	NCK adaptor protein 2	0.284
FKBP1A	FK506 binding protein 1A, 12kDa	0.257
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.250
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.242
PTPRB	protein tyrosine phosphatase, receptor type, B	0.241	Human
ANGPT2	angiopoietin 2	0.234
BMP2	bone morphogenetic protein 2	0.230
SFN	stratifin	0.225
EPHA2	EPH receptor A2	0.217	Human
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.195
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.182
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.180
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.168
ENG	endoglin	0.163
GAB1	GRB2-associated binding protein 1	0.156
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.143
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.119
S100A6	S100 calcium binding protein A6	0.111	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.106
EFNA1	ephrin-A1	0.104	Human
ANXA2	annexin A2	0.100
ZNF746	zinc finger protein 746	0.097
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.097
NCF1	neutrophil cytosolic factor 1	0.093
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.089	Mouse
S100A9	S100 calcium binding protein A9	0.088	Human
PGF	placental growth factor	0.081	Human
PXN	paxillin	0.080	Human
ILK	integrin-linked kinase	0.079
ANXA1	annexin A1	0.076
EFNA5	ephrin-A5	0.072
SMAD7	SMAD family member 7	0.071
AREG	amphiregulin	0.068
S100A8	S100 calcium binding protein A8	0.067	Human
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.066
GDF5	growth differentiation factor 5	0.065
APC	adenomatous polyposis coli	0.065
DSP	desmoplakin	0.064
PDGFA	platelet-derived growth factor alpha polypeptide	0.064	Human
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.062
TGFB1	transforming growth factor, beta 1	0.057
PLCG1	phospholipase C, gamma 1	0.056
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.055
ADRBK1	adrenergic, beta, receptor kinase 1	0.055
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.051
S100A2	S100 calcium binding protein A2	0.051	Human
FKBP4	FK506 binding protein 4, 59kDa	0.050
GIPC1	GIPC PDZ domain containing family, member 1	0.049
NCF2	neutrophil cytosolic factor 2	0.047
BMPR1A	bone morphogenetic protein receptor, type IA	0.046	Human
EPHA7	EPH receptor A7	0.046	Human
AKIP1	A kinase (PRKA) interacting protein 1	0.045
IQGAP1	IQ motif containing GTPase activating protein 1	0.045
TEK	TEK tyrosine kinase, endothelial	0.045
TMSB10	thymosin beta 10	0.044
GRB7	growth factor receptor-bound protein 7	0.044
TGFB3	transforming growth factor, beta 3	0.043
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.043
ANGPT1	angiopoietin 1	0.042
LIMK1	LIM domain kinase 1	0.042
PDGFC	platelet derived growth factor C	0.042
RUNDC3A	RUN domain containing 3A	0.041
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.039	Rat
PRKG1	protein kinase, cGMP-dependent, type I	0.038
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.038
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.037
S100A4	S100 calcium binding protein A4	0.037	Human
SYNJ1	synaptojanin 1	0.036
TSC2	tuberous sclerosis 2	0.036
RYR2	ryanodine receptor 2 (cardiac)	0.036
TRIP6	thyroid hormone receptor interactor 6	0.036
TGFBR1	transforming growth factor, beta receptor 1	0.036	Human
DPYSL4	dihydropyrimidinase-like 4	0.034
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.034
ACVR1	activin A receptor, type I	0.032	Human
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.032
LMNA	lamin A/C	0.031
PHC2	polyhomeotic homolog 2 (Drosophila)	0.031
HOXA1	homeobox A1	0.031
MARK3	MAP/microtubule affinity-regulating kinase 3	0.031
ZYX	zyxin	0.031
AGER	advanced glycosylation end product-specific receptor	0.030
TNK2	tyrosine kinase, non-receptor, 2	0.030
AKAP11	A kinase (PRKA) anchor protein 11	0.030
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.028
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.028
RALGDS	ral guanine nucleotide dissociation stimulator	0.028
BMP1	bone morphogenetic protein 1	0.028
DPPA4	developmental pluripotency associated 4	0.027
MSN	moesin	0.027
LGALS3	lectin, galactoside-binding, soluble, 3	0.027
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.027	Human
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.026
EZR	ezrin	0.026
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.026
RAP1A	RAP1A, member of RAS oncogene family	0.025
SORBS3	sorbin and SH3 domain containing 3	0.024
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.024
NCL	nucleolin	0.024
MAPK8	mitogen-activated protein kinase 8	0.024
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.024
S100P	S100 calcium binding protein P	0.024	Human
FEM1B	fem-1 homolog b (C. elegans)	0.023
CSK	c-src tyrosine kinase	0.023
PRKCD	protein kinase C, delta	0.022
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.022
FAF1	Fas (TNFRSF6) associated factor 1	0.022
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.022
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.022
COL6A1	collagen, type VI, alpha 1	0.021
ATXN1	ataxin 1	0.021
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.020
FURIN	furin (paired basic amino acid cleaving enzyme)	0.020
PHF21A	PHD finger protein 21A	0.020
ACVR1B	activin A receptor, type IB	0.020	Human
DIAPH1	diaphanous homolog 1 (Drosophila)	0.020
GHR	growth hormone receptor	0.020
AHNAK	AHNAK nucleoprotein	0.020
KRT8	keratin 8	0.019
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.019
GAB2	GRB2-associated binding protein 2	0.019
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.019
USP15	ubiquitin specific peptidase 15	0.019
FLT4	fms-related tyrosine kinase 4	0.018	Human
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.017
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.017
RYBP	RING1 and YY1 binding protein	0.017
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.017
MAP2K3	mitogen-activated protein kinase kinase 3	0.017
BMP4	bone morphogenetic protein 4	0.016
ATF7IP	activating transcription factor 7 interacting protein	0.016
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.016
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.016
KRT18	keratin 18	0.016
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.016	Rat
S100A11	S100 calcium binding protein A11	0.016	Human
EPHA3	EPH receptor A3	0.016
HSPG2	heparan sulfate proteoglycan 2	0.016
NRP2	neuropilin 2	0.016
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.016
FN1	fibronectin 1	0.016
MAP2	microtubule-associated protein 2	0.015
PARVA	parvin, alpha	0.015
PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme	0.015
LDLR	low density lipoprotein receptor	0.015
PHLDA3	pleckstrin homology-like domain, family A, member 3	0.015
VEGFC	vascular endothelial growth factor C	0.015	Human
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.015
RHOG	ras homolog gene family, member G (rho G)	0.014	Human
TIMP3	TIMP metallopeptidase inhibitor 3	0.014
THBS1	thrombospondin 1	0.014
CTTN	cortactin	0.014
RHOC	ras homolog gene family, member C	0.014
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.014
FNDC3B	fibronectin type III domain containing 3B	0.014
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.014
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.014
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.013
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.013
ITSN2	intersectin 2	0.013
CNKSR1	connector enhancer of kinase suppressor of Ras 1	0.013
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.013
EMCN	endomucin	0.013
JAG1	jagged 1	0.013
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.013
AKAP10	A kinase (PRKA) anchor protein 10	0.013
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.013
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.013
S100A12	S100 calcium binding protein A12	0.013	Human
ZNF426	zinc finger protein 426	0.012
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.012
SETD7	SET domain containing (lysine methyltransferase) 7	0.012
WNK1	WNK lysine deficient protein kinase 1	0.012
VCL	vinculin	0.012
CD34	CD34 molecule	0.012
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.012
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.012
PLAU	plasminogen activator, urokinase	0.012
TFRC	transferrin receptor (p90, CD71)	0.012
SHB	Src homology 2 domain containing adaptor protein B	0.012
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.012
ATP8	ATP synthase F0 subunit 8	0.012
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.012	Human
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.012
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.012
LRP1	low density lipoprotein receptor-related protein 1	0.012
LAMB3	laminin, beta 3	0.012
BCR	breakpoint cluster region	0.012
PDE2A	phosphodiesterase 2A, cGMP-stimulated	0.012
PI3	peptidase inhibitor 3, skin-derived	0.012
MYH9	myosin, heavy chain 9, non-muscle	0.012
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.012
CTSB	cathepsin B	0.011
ZMYND11	zinc finger, MYND-type containing 11	0.011
ACVRL1	activin A receptor type II-like 1	0.011
KIAA1539	KIAA1539	0.011
DUSP7	dual specificity phosphatase 7	0.011
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.011
PSG5	pregnancy specific beta-1-glycoprotein 5	0.011
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.011
MCAM	melanoma cell adhesion molecule	0.011
USP2	ubiquitin specific peptidase 2	0.011
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.011
HIPK3	homeodomain interacting protein kinase 3	0.011
REPS2	RALBP1 associated Eps domain containing 2	0.011
EPHB6	EPH receptor B6	0.011	Human
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.011
BGN	biglycan	0.011
GPR116	G protein-coupled receptor 116	0.011
EHD2	EH-domain containing 2	0.011
RICTOR	RPTOR independent companion of MTOR, complex 2	0.011
NOTCH4	notch 4	0.011
EPAS1	endothelial PAS domain protein 1	0.011
PDLIM4	PDZ and LIM domain 4	0.011
ANTXR2	anthrax toxin receptor 2	0.011
TRIM9	tripartite motif containing 9	0.011
ANGPTL4	angiopoietin-like 4	0.011
JUB	jub, ajuba homolog (Xenopus laevis)	0.011
EFHD2	EF-hand domain family, member D2	0.010
LUM	lumican	0.010
PLAUR	plasminogen activator, urokinase receptor	0.010
GSK3B	glycogen synthase kinase 3 beta	0.010
TGFB2	transforming growth factor, beta 2	0.010
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.010
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.010
EGR1	early growth response 1	0.010
COL18A1	collagen, type XVIII, alpha 1	0.010
SIK3	SIK family kinase 3	0.010
IGF2	insulin-like growth factor 2 (somatomedin A)	0.010
INHBA	inhibin, beta A	0.010
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.010
MAPT	microtubule-associated protein tau	0.010
CSTA	cystatin A (stefin A)	0.010
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.010
KLF5	Kruppel-like factor 5 (intestinal)	0.010